Suchergebnisse - "eGFR"

Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Autoren: Rinne, Sara S. Yin, Wen Li, Ruonan et al.

Quelle: ACS Pharmacology & Translational Science. 8(11):3872-3885

Schlagwörter: ABD, ADC, affibody, antibody, cancer, DM1, EGFR, epidermal growth factor receptor

Dateibeschreibung: print

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-373615
https://doi.org/10.1021/acsptsci.5c00079

Posible rol de las neuregulinas en la fisiología del tejido adiposo en asociación con obesidad y diabetes mellitus tipo 2

Autoren: Martínez Merchan, Cristina

Weitere Verfasser: University/Department: Universitat de Girona. Departament de Ciències Mèdiques

Thesis Advisors: Moreno Navarrete, José María, Fernández-Real Lemos, José Manuel, Ricart, Wifredo

Quelle: TDX (Tesis Doctorals en Xarxa)

Schlagwörter: Neuregulines, Neuregulinas, Neuregulins, Teixit adipós, Tejido adiposo, Adipose tissue, Adipogènesi, Adipogénesis, Adipogenesis, EGFR, Resistència a la insulina, Resistencia a la insulina, Insulin resistance, Respiració mitocondrial, Respiración mitocondrial, Mitochondrial respiration, Obesitat, Obesidad, Obesity

Time: 616.4

Dateibeschreibung: application/pdf

Zugangs-URL: http://hdl.handle.net/10803/689257

Inhibition of sialyltransferases in pancreatic cancer: effects on the EGFR pathway and on the tumour phenotype

Autoren: Miró Domènech, Laura

Weitere Verfasser: University/Department: Universitat de Girona. Departament de Biologia

Thesis Advisors: Peracaula Miró, Rosa, Massaguer i Vall-llovera, Anna

Quelle: TDX (Tesis Doctorals en Xarxa)

Schlagwörter: Càncer de pàncrees, Cáncer de páncreas, Pancreatic cancer, Àcid siàlic, Ácido siálico, Sialic acid, EGFR, Receptor del factor de creixement epidèrmic, Receptor del factor de crecimiento epidérmico, Epidermal growth factor receptor, Sialyl-Lewis X, Inhibidor de sialiltransferases, Inhibidor de sialiltransferasas, Sialyltransferase inhibitor, Fenotip tumoral, Fenotipo tumoral, Tumour phenotype, Ratolins singènics, Ratones singénicos, Syngeneic mice

Dateibeschreibung: application/pdf

Zugangs-URL: http://hdl.handle.net/10803/688165

Updated treatment recommendations for systemic treatment: from the ESMO non-oncogene-addicted metastatic NSCLC Living Guideline: from the ESMO oncogene-addicted metastatic NSCLC Living Guideline†

Autoren: Hendriks, L E L Cortiula, F Martins-Branco, D et al.

Quelle: Annals of Oncology. 36:1223-1227

Schlagwörter: BRAF mutation, immune checkpoint inhibitor (ICI), metastatic non-oncogene-addicted non-small cell lung cancer (mNSCLC), metastatic oncogene-addicted non-small cell lung cancer (mNSCLC), treatment, combination treatment, KRAS G12C mutation, Chemotherapy (ChT), EGFR mutation, guideline

Zugangs-URL: https://cris.maastrichtuniversity.nl/en/publications/6d146f89-9a81-407e-a2a9-8b3621575e83
https://doi.org/10.1016/j.annonc.2025.06.007
https://cris.maastrichtuniversity.nl/en/publications/02e20350-8a22-429d-8d97-32f5c06a4580
https://doi.org/10.1016/j.annonc.2025.06.004

Network pharmacology and molecular dynamics simulation reveal antineoplastic potential of Antarctic sponge-derived suberitenones

Autoren: Bhowmik, Prasenjit Mallick, Rahul Duttaroy, Asim K.

Quelle: Frontiers in Chemistry. 13

Schlagwörter: network pharmacology, molecular docking, molecular dynamics simulation, suberitenone, CASP3, MAPK3, EGFR

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-561470
https://doi.org/10.3389/fchem.2025.1545834

Estimation of kidney function in Graves' disease using creatinine and cystatin C

Autoren: Abbaszadeh, Sorena Lundqvist, Martin H. Ljunggren, Östen et al.

Quelle: Endocrine Connections. 14(5)

Schlagwörter: Graves’ disease, hyperthyroidism, estimated glomerular filtration rate (eGFR), kidney function, creatinine, cystatin C

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-554217
https://doi.org/10.1530/EC-24-0698

EGFR Levels in NSCLC Are Associated With Expression of SATB1 and EMT-promoting Factors

Autoren: NATALIA GLATZEL-PLUCINSKA ALEKSANDRA PIOTROWSKA MATEUSZ OLBROMSKI et al.

Quelle: Anticancer Research. 45:3639-3660

Schlagwörter: EGFR, EMT, EMT-promoting factors, NSCLC, SATB1

Zugangs-URL: https://ar.iiarjournals.org/content/45/9/3639
https://doi.org/10.21873/anticanres.17728

Comparing Cystatin C Estimated GFR With Creatinine Estimated GFR in Acute Kidney Injury Recovery

Autoren: Kerry L. Horne Rebecca Packington John Monaghan et al.

Quelle: Kidney International Reports, Vol 10, Iss 8, Pp 2741-2750 (2025)

Schlagwörter: acute kidney injury, cystatin C, creatinine, eGFR, RC870-923, chronic kidney disease, Diseases of the genitourinary system. Urology

Zugangs-URL: https://doaj.org/article/deaa0cda6ff14ccf92cec320e599483a

The Role of Cetuximab in Non-Melanoma Skin Cancer: A Review of Clinical Evidence and Emerging Strategies

Autoren: Nuzzolese I. Cavalieri S. Licitra L. F. et al.

Quelle: Current Treatment Options in Oncology. 26:673-687

Schlagwörter: Basal cell carcinoma, Cetuximab, Cutaneous squamous cell carcinoma, EGFR inhibitors, Epidermal growth factor receptor, Immunotherapy resistance, Non-melanoma skin cancer, Targeted therapy

Zugangs-URL: https://hdl.handle.net/2434/1183457
https://doi.org/10.1007/s11864-025-01335-3

Asprosin Levels in Adults with Type 2 Diabetes Mellitus and Diabetic Kidney Disease: A Systematic Review and Meta-Analysis

Autoren: Jovana Ristic Sena Kodalak Gonzalo Peralta-Jiménez et al.

Quelle: Diabetes Metab Syndr Obes
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 18, Iss Issue 1, Pp 2493-2506 (2025)

Schlagwörter: adipokine, RC581-951, diabetes mellitus, eGFR, Specialties of internal medicine, Review, diabetic kidney disease, asprosin

Zugangs-URL: https://doaj.org/article/0bb336a9183d42a3a870f94533b90eaa

Integrated Traditional Chinese and Western Medicine in Lung Adenocarcinoma with Rare EGFR Mutation and Nephrotic Syndrome: A Case Report

Autoren: Lirong Zhang Liye Cai Luwei Ruan et al.

Quelle: Cancer Manag Res
Cancer Management and Research, Vol Volume 17, Iss Issue 1, Pp 1293-1299 (2025)

Schlagwörter: malignant pleural effusion, Nephrotic syndrome, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Endostar, Case Report, EGFR mutation, lung adenocarcinoma, RC254-282, albumin-bound paclitaxel

Zugangs-URL: https://doaj.org/article/ba7c041c7d1d473e918835af26a1e0a7

Pretreatment GFR Slopes Predict Dapagliflozin Response in IgA Nephropathy

Autoren: Hiroyuki Ueda Nobuo Tsuboi Kei Matsumoto et al.

Quelle: Kidney Int Rep
Kidney International Reports, Vol 10, Iss 7, Pp 2405-2413 (2025)

Schlagwörter: eGFR slope, Clinical Research, dapagliflozin, IgA nephropathy, RC870-923, proteinuria, Diseases of the genitourinary system. Urology

Zugangs-URL: https://doaj.org/article/4999a1406cf54604b5e02c766d4602b0

Efficacy and safety of finerenone in patients with an acute change in estimated glomerular filtration rate in the prespecified FIDELITY pool analysis

Autoren: Sankar D. Navaneethan Stefan D. Anker Gerasimos Filippatos et al.

Quelle: Navaneethan, S D, Anker, S D, Filippatos, G, Pitt, B, Rossing, P, Ruilope, L M, August, P, Brinker, M, Lage, A, Roberts, L, Scott, C, Sarafidis, P & FIDELIO-DKD and FIGARO-DKD Investigators 2025, ' Efficacy and safety of finerenone in patients with an acute change in estimated glomerular filtration rate in the prespecified FIDELITY pool analysis ', Kidney International, vol. 108, no. 1, pp. 136-144 . https://doi.org/10.1016/j.kint.2025.03.018

Schlagwörter: kidney outcomes, nonsteroidal mineralocorticoid receptor antagonist, acute eGFR decline, finerenone, cardiovascular outcomes

Dateibeschreibung: application/pdf

Zugangs-URL: https://curis.ku.dk/ws/files/511225612/1-s2.0-S0085253825003230-main.pdf

Finerenone and Estimated GFR Slope in Type 2 Diabetes and CKD

Autoren: Masayuki Yamanouchi Yuki Oba Hisashi Kamido et al.

Quelle: Kidney Int Rep
Kidney International Reports, Vol 10, Iss 7, Pp 2461-2465 (2025)

Schlagwörter: eGFR slope, type 2 diabetes mellitus, Research Letter, nonsteroidal mineralocorticoid receptor (MR) antagonist, RC870-923, finerenone, chronic kidney disease, Diseases of the genitourinary system. Urology, real-world study

Zugangs-URL: https://doaj.org/article/892c48a796de4e6c8f87914a9886cae2

Exploring 1,3,4-oxadiazole derivatives for hepatocellular carcinoma: synthesis, and bioactivity evaluation

Autoren: Patidar, Mohini Dubey , Raghvendra Deshmukh, Nitin

Quelle: Journal of Applied Pharmaceutical Research, Vol 13, Iss 2, Pp 127-138 (2025)
Journal of Applied Pharmaceutical Research; Vol. 13 No. 2 (2025); 127-138

Schlagwörter: RS1-441, tyrosine kinase inhibitor, Pharmacy and materia medica, Hepatocellular carcinoma, in-vitro study, 1,3,4-oxadiazole, Tyrosine kinase inhibitor, egfr, hepatocellular carcinoma, Therapeutics. Pharmacology, RM1-950, In-vitro study, EGFR

Dateibeschreibung: application/pdf

Zugangs-URL: https://doaj.org/article/9d740e0f905b49c0b767f8a9e92d1030
https://www.japtronline.com/index.php/joapr/article/view/1008

Decoding the Clinical and Molecular Signatures of EGFR Common, Compound, and Uncommon Mutations in NSCLC: A Brief Report

Autoren: Daniele Tavernari Maxime Borgeaud Ximeng Liu et al.

Quelle: Journal of thoracic oncology, vol. 20, no. 4, pp. 500-506

Schlagwörter: Uncommon EGFR mutations, Male, Adult, Aged, 80 and over, Lung Neoplasms, Humans, Female, ErbB Receptors/genetics, Mutation, Lung Neoplasms/genetics, Lung Neoplasms/pathology, Lung Neoplasms/drug therapy, Carcinoma, Non-Small-Cell Lung/genetics, Carcinoma, Non-Small-Cell Lung/pathology, Carcinoma, Non-Small-Cell Lung/drug therapy, Middle Aged, Aged, Co-mutations, Compound EGFR mutations, EGFR, Non–small-cell lung cancer, ErbB Receptors, Carcinoma, Non-Small-Cell Lung

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39694414
https://archive-ouverte.unige.ch/unige:183984
https://doi.org/10.1016/j.jtho.2024.12.012
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_55E39726C98A3
https://serval.unil.ch/notice/serval:BIB_55E39726C98A
https://serval.unil.ch/resource/serval:BIB_55E39726C98A.P001/REF.pdf

Mutaciones del gen del receptor del factor de crecimiento epidérmico (EGFR) en pacientes con carcinoma no microcítico de pulmón: cribado poblacional, significado predictivo y pronóstico y estrategias terapéuticas a la progresión

Autoren: Morán Bueno, María Teresa

Weitere Verfasser: University/Department: Universitat Autònoma de Barcelona. Departament de Medicina

Thesis Advisors: Felip Font, Enriqueta, Rosell Costa, R

Quelle: TDX (Tesis Doctorals en Xarxa)

Schlagwörter: Mutacions d'EGFR, Mutaciones de EGFR, EGFR mutations, Carcinoma no microcític de pulmó, Carcinoma no microcítico de pulmón, Non-small cell lung cancer, Inhibidors de tirsonia quinasa, Inhibidores de tirosina quinasa, Tyrosine kinase inhibitors, Ciències de la Salut

Dateibeschreibung: application/pdf

Zugangs-URL: http://hdl.handle.net/10803/667726

A comparative study of preclinical and clinical molecular imaging response to EGFR inhibition using osimertinib in glioblastoma

Autoren: Ellingson, Benjamin M Okobi, Quincy Chong, Robert et al.

Quelle: Neuro-Oncology Advances. 7(1)

Schlagwörter: 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), 3211 Oncology and Carcinogenesis (for-2020), Biomedical Imaging (rcdc), Brain Disorders (rcdc), Rare Diseases (rcdc), Neurosciences (rcdc), Clinical Research (rcdc), Brain Cancer (rcdc), Cancer (rcdc), 4.2 Evaluation of markers and technologies (hrcs-rac), 4.1 Discovery and preclinical testing of markers and technologies (hrcs-rac), Cancer (hrcs-hc), 3 Good Health and Well Being (sdg), EGFR, FDG PET, glioblastoma, imaging biomarker, osimertinib, molecular imaging, EGFR, FDG PET, glioblastoma, imaging biomarker, molecular imaging, osimertinib

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/0s363429
https://escholarship.org/content/qt0s363429/qt0s363429.pdf

The impact of kidney function on Alzheimer’s disease blood biomarkers: implications for predicting amyloid-β positivity

Autoren: Arslan, Burak Brum, Wagner S Pola, Ilaria et al.

Quelle: Alzheimer's Research & Therapy. 17(1)

Schlagwörter: 32 Biomedical and Clinical Sciences (for-2020), 42 Health Sciences (for-2020), Kidney Disease (rcdc), Acquired Cognitive Impairment (rcdc), Neurosciences (rcdc), Alzheimer's Disease (rcdc), Dementia (rcdc), Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) (rcdc), Aging (rcdc), Neurodegenerative (rcdc), Clinical Research (rcdc), Prevention (rcdc), Brain Disorders (rcdc), 4.1 Discovery and preclinical testing of markers and technologies (hrcs-rac), 2.1 Biological and endogenous factors (hrcs-rac), 4.2 Evaluation of markers and technologies (hrcs-rac), Renal and urogenital (hrcs-hc), Neurological (hrcs-hc), Humans (mesh), Male (mesh), Female (mesh), Alzheimer Disease (mesh), Amyloid beta-Peptides (mesh), Biomarkers (mesh), Aged (mesh), Glomerular Filtration Rate (mesh), Cognitive Dysfunction (mesh), tau Proteins (mesh), Peptide Fragments (mesh), Aged, 80 and over (mesh), Creatinine (mesh), Middle Aged (mesh), Cohort Studies (mesh), Positron-Emission Tomography (mesh), Glial Fibrillary Acidic Protein (mesh), Neurofilament Proteins (mesh), Humans (mesh), Alzheimer Disease (mesh), Creatinine (mesh), Glial Fibrillary Acidic Protein (mesh), Neurofilament Proteins (mesh), Peptide Fragments (mesh), tau Proteins (mesh), Positron-Emission Tomography (mesh), Glomerular Filtration Rate (mesh), Cohort Studies (mesh), Aged (mesh), Aged, 80 and over (mesh), Middle Aged (mesh), Female (mesh), Male (mesh), Amyloid beta-Peptides (mesh), Biomarkers (mesh), Cognitive Dysfunction (mesh), Amyloid, GFAP, Kidney impairment, NfL, eGFR, p-tau, Humans (mesh), Male (mesh), Female (mesh), Alzheimer Disease (mesh), Amyloid beta-Peptides (mesh), Biomarkers (mesh), Aged (mesh), Glomerular Filtration Rate (mesh), Cognitive Dysfunction (mesh), tau Proteins (mesh), Peptide Fragments (mesh), Aged, 80 and over (mesh), Creatinine (mesh), Middle Aged (mesh), Cohort Studies (mesh), Positron-Emission Tomography (mesh), Glial Fibrillary Acidic Protein (mesh), Neurofilament Proteins (mesh), 11 Medical and Health Sciences (for), 32 Biomedical and clinical sciences (for-2020), 42 Health sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/5zq824x5
https://escholarship.org/content/qt5zq824x5/qt5zq824x5.pdf

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

Autoren: Tharsagini V. Nanthaprakash Campbell W. Gourlay Ina Oehme et al.

Quelle: FEBS Open Bio, Vol 15, Iss 11, Pp 1854-1873 (2025)

Schlagwörter: acquired drug resistance, cell line, EGFR, EGFR tyrosine kinase inhibitor, non‐small cell lung cancer, plasticity, Biology (General), QH301-705.5

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2211-5463

Zugangs-URL: https://doaj.org/article/e2aaa71bec0e4306a66a7f526ec32d48