Výsledky vyhľadávania - "diffuse intrinsic pontine glioma"

Diffuse pontine glioma (DPG): shorter or longer treatment time?

Autori: Ghalibafian M Mirzaei S Sadeghi Y a ďalší

Zdroj: Journal of neuro-oncology [J Neurooncol] 2025 Oct 24; Vol. 176 (1), pp. 40. Date of Electronic Publication: 2025 Oct 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Brain Stem Neoplasms*/radiotherapy , Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/therapy , Brain Stem Neoplasms*/mortality , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Diffuse Intrinsic Pontine Glioma*/pathology , Diffuse Intrinsic Pontine Glioma*/therapy , Glioma*/radiotherapy , Glioma*/pathology , Radiation Dose Hypofractionation*, Humans ; Male ; Female ; Adult ; Middle Aged ; Young Adult ; Aged ; Retrospective Studies ; Adolescent ; Child ; Prognosis ; Follow-Up Studies ; Time Factors ; Survival Rate

Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma.

Autori: Song EZ Timpanaro A Meechan M a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Nov 11; Vol. 16 (1), pp. 9914. Date of Electronic Publication: 2025 Nov 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Receptors, CXCR3*/genetics , Receptors, CXCR3*/metabolism , Receptors, CXCR3*/immunology , Immunotherapy, Adoptive*/methods , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , B7 Antigens*/metabolism , B7 Antigens*/immunology , B7 Antigens*/genetics , Diffuse Intrinsic Pontine Glioma*/therapy , Diffuse Intrinsic Pontine Glioma*/immunology , Diffuse Intrinsic Pontine Glioma*/genetics , Diffuse Intrinsic Pontine Glioma*/pathology , Brain Stem Neoplasms*/therapy , Brain Stem Neoplasms*/immunology , Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/genetics, Animals ; Humans ; Mice ; Cell Movement/immunology ; Cell Line, Tumor ; Chemokine CXCL10/metabolism ; Chemokine CXCL10/genetics ; Xenograft Model Antitumor Assays ; Female

Postradiation MR Imaging Features in Molecular and Mutational Analyses in Pontine Pediatric Diffuse Midline Gliomas.

Autori: Rameh V Ziaei A Vajapeyam S a ďalší

Zdroj: AJNR. American journal of neuroradiology [AJNR Am J Neuroradiol] 2025 Nov 03; Vol. 46 (11), pp. 2385-2392. Date of Electronic Publication: 2025 Nov 03.

Spôsob vydávania: Journal Article; Multicenter Study

Informácie o časopise: Publisher: American Society of Neuroradiology Country of Publication: United States NLM ID: 8003708 Publication Model: Electronic Cited Medium: Internet ISSN: 1936-959X (Electronic) Linking ISSN: 01956108 NLM ISO Abbreviation: AJNR Am J Neuroradiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Brain Stem Neoplasms*/genetics , Brain Stem Neoplasms*/radiotherapy , Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/diagnostic imaging , Brain Stem Neoplasms*/mortality , Glioma*/genetics , Glioma*/radiotherapy , Glioma*/pathology , Magnetic Resonance Imaging*/methods , Histones*/genetics , Diffuse Intrinsic Pontine Glioma*/genetics , Diffuse Intrinsic Pontine Glioma*/radiotherapy, Humans ; Child ; Male ; Female ; Adolescent ; Child, Preschool ; Infant ; Mutation ; Treatment Outcome ; DNA Mutational Analysis

Three and Four Courses of Radiation for Children With Recurrent Diffuse Intrinsic Pontine Glioma.

Autori: Shariff N Lausch A Bouffet E a ďalší

Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2025 Nov; Vol. 72 (11), pp. e31695. Date of Electronic Publication: 2025 Apr 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE

Výrazy zo slovníka MeSH: Brain Stem Neoplasms*/radiotherapy , Brain Stem Neoplasms*/mortality , Brain Stem Neoplasms*/pathology , Neoplasm Recurrence, Local*/radiotherapy , Neoplasm Recurrence, Local*/mortality , Neoplasm Recurrence, Local*/pathology , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Diffuse Intrinsic Pontine Glioma*/mortality , Glioma*/radiotherapy , Glioma*/mortality , Glioma*/pathology , Re-Irradiation*, Humans ; Male ; Child ; Retrospective Studies ; Female ; Child, Preschool ; Adolescent ; Survival Rate ; Infant

Nimotuzumab Combined With Chemoradiation Therapy in Newly Diagnosed Pediatric Diffuse Intrinsic Pontine Glioma.

Autori: Liu Y Liu C Wang G a ďalší

Zdroj: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2025 Nov 01; Vol. 123 (3), pp. 839-847. Date of Electronic Publication: 2025 Jun 19.

Spôsob vydávania: Journal Article; Multicenter Study

Informácie o časopise: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 7603616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-355X (Electronic) Linking ISSN: 03603016 NLM ISO Abbreviation: Int J Radiat Oncol Biol Phys Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diffuse Intrinsic Pontine Glioma*/therapy , Diffuse Intrinsic Pontine Glioma*/mortality , Antibodies, Monoclonal, Humanized*/therapeutic use , Antibodies, Monoclonal, Humanized*/adverse effects , Antibodies, Monoclonal, Humanized*/administration & dosage , Chemoradiotherapy*/methods , Chemoradiotherapy*/adverse effects , Brain Stem Neoplasms*/therapy , Brain Stem Neoplasms*/mortality, Humans ; Child ; Male ; Female ; Adolescent ; Child, Preschool ; Temozolomide/therapeutic use ; Temozolomide/administration & dosage ; Temozolomide/adverse effects ; Prospective Studies ; Progression-Free Survival ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use

Evaluating the Role of Re-Irradiation in the Management of DIPG: A Systematic Review and Meta-Analysis of Current Evidence.

Autori: Nuryadi E Raissa N Handoko H a ďalší

Zdroj: Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2025 Oct 01; Vol. 26 (10), pp. 3561-3570. Date of Electronic Publication: 2025 Oct 01.

Spôsob vydávania: Journal Article; Systematic Review; Meta-Analysis

Informácie o časopise: Publisher: Asian Pacific Organization for Cancer Prevention Country of Publication: Thailand NLM ID: 101130625 Publication Model: Electronic Cited Medium: Internet ISSN: 2476-762X (Electronic) Linking ISSN: 15137368 NLM ISO Abbreviation: Asian Pac J Cancer Prev Subsets: MEDLINE

Výrazy zo slovníka MeSH: Re-Irradiation*/methods , Re-Irradiation*/mortality , Brain Stem Neoplasms*/radiotherapy , Brain Stem Neoplasms*/mortality , Brain Stem Neoplasms*/pathology , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Diffuse Intrinsic Pontine Glioma*/mortality , Diffuse Intrinsic Pontine Glioma*/pathology , Neoplasm Recurrence, Local*/radiotherapy , Neoplasm Recurrence, Local*/pathology, Humans ; Survival Rate ; Prognosis

Managing diffuse intrinsic Pontine glioma (DIPG) through japan's pediatric home medical care (PHMC) system, originally designed for medically complex children.

Autori: Osumi T Yamamoto M Inaba N a ďalší

Zdroj: BMC palliative care [BMC Palliat Care] 2025 Sep 29; Vol. 24 (1), pp. 236. Date of Electronic Publication: 2025 Sep 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101088685 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-684X (Electronic) Linking ISSN: 1472684X NLM ISO Abbreviation: BMC Palliat Care Subsets: MEDLINE

Výrazy zo slovníka MeSH: Home Care Services*/standards , Home Care Services*/statistics & numerical data , Home Care Services*/organization & administration , Diffuse Intrinsic Pontine Glioma*/therapy , Diffuse Intrinsic Pontine Glioma*/complications , Diffuse Intrinsic Pontine Glioma*/psychology , Brain Stem Neoplasms*/therapy, Humans ; Male ; Female ; Retrospective Studies ; Japan ; Child ; Child, Preschool ; Adolescent ; Cohort Studies ; Infant ; Palliative Care/methods ; Pediatrics/methods ; Quality of Life/psychology

Phase 1 dose-escalation trial using convection-enhanced delivery of radio-immunotheranostic 124I-Omburtamab for diffuse intrinsic pontine glioma.

Autori: Souweidane MM Bander ED Zanzonico P a ďalší

Zdroj: Neuro-oncology [Neuro Oncol] 2025 Sep 17; Vol. 27 (8), pp. 2117-2126.

Spôsob vydávania: Journal Article; Clinical Trial, Phase I

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/radiotherapy , Brain Stem Neoplasms*/therapy , Brain Stem Neoplasms*/diagnostic imaging , Diffuse Intrinsic Pontine Glioma*/diagnostic imaging , Diffuse Intrinsic Pontine Glioma*/drug therapy , Diffuse Intrinsic Pontine Glioma*/pathology , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Iodine Radioisotopes*/administration & dosage , Radiopharmaceuticals*/administration & dosage, Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Convection ; Follow-Up Studies ; Prognosis ; Survival Rate

Re-irradiation in progressive diffuse infiltrative pontine glioma in children and young adults.

Autori: Kahvecioglu A Cengiz M Burca Aydin G a ďalší

Zdroj: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] [Strahlenther Onkol] 2025 Sep; Vol. 201 (9), pp. 894-902. Date of Electronic Publication: 2025 Mar 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Urban & Vogel Country of Publication: Germany NLM ID: 8603469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-099X (Electronic) Linking ISSN: 01797158 NLM ISO Abbreviation: Strahlenther Onkol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Re-Irradiation*/methods , Brain Stem Neoplasms*/radiotherapy , Brain Stem Neoplasms*/mortality , Brain Stem Neoplasms*/pathology , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Diffuse Intrinsic Pontine Glioma*/mortality , Diffuse Intrinsic Pontine Glioma*/pathology , Glioma*/radiotherapy , Glioma*/mortality, Humans ; Child ; Adolescent ; Female ; Young Adult ; Male ; Child, Preschool ; Disease Progression ; Retrospective Studies ; Radiotherapy Dosage ; Combined Modality Therapy

The oncolytic adenovirus Ad-TD-nsIL12 in primary or progressive pediatric IDH wild-type diffuse intrinsic pontine glioma results of two phase I clinical trials.

Autori: Qian X Ning W Yang J a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Jul 28; Vol. 16 (1), pp. 6934. Date of Electronic Publication: 2025 Jul 28.

Spôsob vydávania: Journal Article; Clinical Trial, Phase I

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Oncolytic Virotherapy*/methods , Oncolytic Virotherapy*/adverse effects , Adenoviridae*/genetics , Diffuse Intrinsic Pontine Glioma*/therapy , Diffuse Intrinsic Pontine Glioma*/genetics , Diffuse Intrinsic Pontine Glioma*/mortality , Diffuse Intrinsic Pontine Glioma*/pathology , Brain Stem Neoplasms*/therapy , Brain Stem Neoplasms*/genetics , Brain Stem Neoplasms*/mortality , Brain Stem Neoplasms*/pathology , Oncolytic Viruses*/genetics , Isocitrate Dehydrogenase*/genetics, Humans ; Male ; Female ; Child ; Child, Preschool ; Adolescent ; Treatment Outcome

A Multicenter Phase II Trial of Nimustine Hydrochloride Administered via Convection-Enhanced Delivery in Children With DIPG.

Autori: Saito R Kanamori M Arakawa Y a ďalší

Zdroj: Cancer science [Cancer Sci] 2025 Jun; Vol. 116 (6), pp. 1679-1690. Date of Electronic Publication: 2025 Mar 27.

Spôsob vydávania: Journal Article; Clinical Trial, Phase II; Multicenter Study

Informácie o časopise: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Brain Stem Neoplasms*/drug therapy , Brain Stem Neoplasms*/mortality , Brain Stem Neoplasms*/pathology , Diffuse Intrinsic Pontine Glioma*/drug therapy , Diffuse Intrinsic Pontine Glioma*/mortality , Nimustine*/administration & dosage , Nimustine*/adverse effects , Antineoplastic Agents*/administration & dosage, Humans ; Child ; Female ; Male ; Child, Preschool ; Adolescent ; Young Adult ; Convection ; Treatment Outcome ; Drug Delivery Systems/methods ; Survival Rate

Phase I Study of Vorinostat and Temsirolimus in Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma.

Autori: Stitzlein LM Baig MU Chandra J a ďalší

Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2025 May; Vol. 72 (5), pp. e31619. Date of Electronic Publication: 2025 Feb 25.

Spôsob vydávania: Journal Article; Clinical Trial, Phase I

Informácie o časopise: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE

Výrazy zo slovníka MeSH: Brain Stem Neoplasms*/drug therapy , Brain Stem Neoplasms*/pathology , Diffuse Intrinsic Pontine Glioma*/drug therapy , Diffuse Intrinsic Pontine Glioma*/pathology , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/adverse effects, Humans ; Vorinostat/administration & dosage ; Vorinostat/adverse effects ; Male ; Female ; Child ; Maximum Tolerated Dose ; Sirolimus/analogs & derivatives ; Sirolimus/administration & dosage ; Sirolimus/adverse effects ; Child, Preschool ; Adolescent ; Follow-Up Studies

Re-Irradiation for the Progressive Pediatric Diffuse Intrinsic Pontine Glioma: A Report on 109 Children From a Single Center.

Autori: Zaghloul MS Bishr MK Refaat A a ďalší

Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2025 Apr; Vol. 72 (4), pp. e31587. Date of Electronic Publication: 2025 Feb 04.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE

Výrazy zo slovníka MeSH: Brain Stem Neoplasms*/radiotherapy , Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/mortality , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Diffuse Intrinsic Pontine Glioma*/pathology , Diffuse Intrinsic Pontine Glioma*/mortality , Re-Irradiation*/mortality, Humans ; Male ; Female ; Child ; Retrospective Studies ; Child, Preschool ; Adolescent ; Survival Rate ; Disease Progression ; Follow-Up Studies ; Infant ; Prognosis

Exploring the tumor microenvironment in diffuse intrinsic pontine glioma: immunological insights and therapeutic challenges.

Autori: Van den Ende B Riva M De Smet F a ďalší

Zdroj: Journal for immunotherapy of cancer [J Immunother Cancer] 2025 Jun 12; Vol. 13 (6). Date of Electronic Publication: 2025 Jun 12.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tumor Microenvironment*/immunology , Diffuse Intrinsic Pontine Glioma*/immunology , Diffuse Intrinsic Pontine Glioma*/therapy , Diffuse Intrinsic Pontine Glioma*/pathology , Brain Stem Neoplasms*/immunology , Brain Stem Neoplasms*/therapy , Brain Stem Neoplasms*/pathology , Immunotherapy*/methods, Humans

Targeting the SP/KLF Transcriptional Regulatory Network Synergizes with HDAC Inhibition to Impede Progression of H3K27M Diffuse Intrinsic Pontine Glioma.

Autori: Kong Y Wang F Jing R a ďalší

Zdroj: Cancer research [Cancer Res] 2025 Jun 02; Vol. 85 (11), pp. 2100-2116.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diffuse Intrinsic Pontine Glioma*/genetics , Diffuse Intrinsic Pontine Glioma*/drug therapy , Diffuse Intrinsic Pontine Glioma*/pathology , Diffuse Intrinsic Pontine Glioma*/metabolism , Histone Deacetylase Inhibitors*/pharmacology , Brain Stem Neoplasms*/genetics , Brain Stem Neoplasms*/drug therapy , Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/metabolism , Kruppel-Like Transcription Factors*/genetics , Kruppel-Like Transcription Factors*/metabolism , Kruppel-Like Transcription Factors*/antagonists & inhibitors , Gene Regulatory Networks*/drug effects , Histones*/genetics , Sp1 Transcription Factor*/genetics , Sp1 Transcription Factor*/metabolism, Humans ; Animals ; Mice ; Xenograft Model Antitumor Assays ; Gene Expression Regulation, Neoplastic/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Synergism ; Disease Progression ; Mutation ; Plicamycin/pharmacology ; Plicamycin/analogs & derivatives

Determination of the Intralesional Distribution of Theranostic ¹²⁴ I-Omburtamab Convection-Enhanced Delivery in Treatment of Diffuse Intrinsic Pontine Glioma.

Autori: França Velo A Giantini Larsen A Humm JL a ďalší

Zdroj: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2025 Jun 02; Vol. 66 (6), pp. 886-891. Date of Electronic Publication: 2025 Jun 02.

Spôsob vydávania: Journal Article; Clinical Trial, Phase I

Informácie o časopise: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Iodine Radioisotopes*/therapeutic use , Diffuse Intrinsic Pontine Glioma*/diagnostic imaging , Diffuse Intrinsic Pontine Glioma*/metabolism , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Convection* , Brain Stem Neoplasms*/diagnostic imaging , Brain Stem Neoplasms*/metabolism , Brain Stem Neoplasms*/radiotherapy , Drug Delivery Systems* , Antibodies, Monoclonal*/therapeutic use , Antibodies, Monoclonal*/pharmacokinetics , Antibodies, Monoclonal*/administration & dosage , Glioma*/diagnostic imaging , Glioma*/metabolism , Glioma*/radiotherapy , Theranostic Nanomedicine*/methods, Humans ; Child ; Male ; Female ; Child, Preschool ; Adolescent ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; Tissue Distribution ; Infant

Re-irradiation for children with diffuse intrinsic pontine glioma and diffuse midline glioma.

Autori: Shariff N Moreno AS Bennett J a ďalší

Zdroj: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2025 Jun; Vol. 207, pp. 110865. Date of Electronic Publication: 2025 Mar 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Re-Irradiation*/methods , Brain Stem Neoplasms*/radiotherapy , Brain Stem Neoplasms*/mortality , Brain Stem Neoplasms*/pathology , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Diffuse Intrinsic Pontine Glioma*/mortality , Glioma*/radiotherapy , Glioma*/mortality , Glioma*/pathology, Humans ; Child ; Male ; Female ; Child, Preschool ; Retrospective Studies ; Adolescent ; Infant ; Neoplasm Recurrence, Local/radiotherapy

Inhibition of mitochondrial bioenergetics and hypoxia to radiosensitize diffuse intrinsic pontine glioma.

Autori: Shen H Mudassar F Ma S a ďalší

Zdroj: Neuro-oncology [Neuro Oncol] 2025 May 15; Vol. 27 (4), pp. 1061-1075.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mitochondria*/metabolism , Mitochondria*/radiation effects , Mitochondria*/drug effects , Diffuse Intrinsic Pontine Glioma*/metabolism , Diffuse Intrinsic Pontine Glioma*/pathology , Diffuse Intrinsic Pontine Glioma*/radiotherapy , Brain Stem Neoplasms*/metabolism , Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/radiotherapy , Energy Metabolism* , Radiation Tolerance* , Glioma*/metabolism , Glioma*/radiotherapy , Glioma*/pathology, Humans ; Animals ; Mice ; Xenograft Model Antitumor Assays ; Tumor Cells, Cultured

An oncohistone-driven H3.3K27M/CREB5/ID1 axis maintains the stemness and malignancy of diffuse intrinsic pontine glioma.

Autori: Zhou W Xu C Yang S a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Apr 17; Vol. 16 (1), pp. 3675. Date of Electronic Publication: 2025 Apr 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Histones*/metabolism , Histones*/genetics , Diffuse Intrinsic Pontine Glioma*/genetics , Diffuse Intrinsic Pontine Glioma*/pathology , Diffuse Intrinsic Pontine Glioma*/metabolism , Brain Stem Neoplasms*/genetics , Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/metabolism , Cyclic AMP Response Element-Binding Protein*/metabolism , Cyclic AMP Response Element-Binding Protein*/genetics , Neoplastic Stem Cells*/metabolism , Neoplastic Stem Cells*/pathology , Glioma*/genetics , Glioma*/pathology , Glioma*/metabolism, Humans ; Animals ; Mice ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Transcription Factors/metabolism ; Transcription Factors/genetics ; DNA Helicases/metabolism ; DNA Helicases/genetics ; Nuclear Proteins/metabolism ; Nuclear Proteins/genetics ; Epigenesis, Genetic ; Signal Transduction ; Inhibitor of Differentiation Protein 1

Anti-OAcGD2 antibody in combination with ceramide kinase inhibitor mediates potent antitumor cytotoxicity against breast cancer and diffuse intrinsic pontine glioma cells.

Autori: Kasprowicz A Cavdarli S Delannoy P a ďalší

Zdroj: Molecular and cellular biochemistry [Mol Cell Biochem] 2025 Apr; Vol. 480 (4), pp. 2555-2571. Date of Electronic Publication: 2024 Oct 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Phosphotransferases (Alcohol Group Acceptor)*/antagonists & inhibitors , Phosphotransferases (Alcohol Group Acceptor)*/metabolism , Breast Neoplasms*/pathology , Breast Neoplasms*/drug therapy , Breast Neoplasms*/immunology , Breast Neoplasms*/metabolism , Gangliosides*/immunology , Diffuse Intrinsic Pontine Glioma*/pathology , Diffuse Intrinsic Pontine Glioma*/drug therapy , Diffuse Intrinsic Pontine Glioma*/immunology , Diffuse Intrinsic Pontine Glioma*/metabolism , Brain Stem Neoplasms*/pathology , Brain Stem Neoplasms*/drug therapy , Brain Stem Neoplasms*/immunology , Antibodies, Monoclonal*/pharmacology, Humans ; Female ; Cell Line, Tumor ; Animals ; Mice