Search Results - "detection"

Suzetrigine in Equestrian Sports: Optimized Extraction and LC-HRMS Detection Strategies.

Authors: Ajeebsanu MM Koshy SA Karakka Kal AK et al.

Source: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2025 Dec 15; Vol. 39 (23), pp. e10135.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley And Sons Ltd Country of Publication: England NLM ID: 8802365 Publication Model: Print Cited Medium: Internet ISSN: 1097-0231 (Electronic) Linking ISSN: 09514198 NLM ISO Abbreviation: Rapid Commun Mass Spectrom Subsets: MEDLINE

MeSH Terms: Doping in Sports* , Substance Abuse Detection*/methods, Horses/urine ; Animals ; Solid Phase Extraction/methods ; Limit of Detection ; Reproducibility of Results ; Chromatography, Liquid/methods ; Liquid-Liquid Extraction/methods ; Tandem Mass Spectrometry/methods ; Mass Spectrometry/methods

Dual nanozyme sensor enables rapid at-home cancer surveillance.

Authors: Miao P Peng H Zhao X et al.

Source: Talanta [Talanta] 2025 Dec 01; Vol. 295, pp. 128237. Date of Electronic Publication: 2025 May 09.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2984816R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3573 (Electronic) Linking ISSN: 00399140 NLM ISO Abbreviation: Talanta Subsets: MEDLINE

MeSH Terms: Biomarkers, Tumor*/blood , Biosensing Techniques*/methods , Metal Nanoparticles*/chemistry , Neoplasms*/diagnosis , Neoplasms*/blood , Early Detection of Cancer*, Humans ; Carcinoembryonic Antigen/blood ; Smartphone ; Gold/chemistry ; alpha-Fetoproteins/analysis ; Prostate-Specific Antigen/blood ; Limit of Detection ; Copper/chemistry ; Aptamers, Nucleotide/chemistry

A portable fluorescent lateral flow immunoassay system for ultrasensitive point-of-care detection of multiple illicit drugs.

Authors: Li W Cheng X Wang D et al.

Source: Analytical methods : advancing methods and applications [Anal Methods] 2025 Nov 27; Vol. 17 (46), pp. 9454-9466. Date of Electronic Publication: 2025 Nov 27.

Publication Type: Journal Article

Journal Info: Publisher: RSC Pub Country of Publication: England NLM ID: 101519733 Publication Model: Electronic Cited Medium: Internet ISSN: 1759-9679 (Electronic) Linking ISSN: 17599660 NLM ISO Abbreviation: Anal Methods Subsets: MEDLINE

MeSH Terms: Illicit Drugs*/analysis , Substance Abuse Detection*/methods , Substance Abuse Detection*/instrumentation , Point-of-Care Systems*, Quantum Dots/chemistry ; Immunoassay/methods ; Immunoassay/instrumentation ; Humans ; Limit of Detection ; Cocaine/analogs & derivatives ; Cocaine/analysis ; Silicon Dioxide/chemistry

Development of smartphone-based AIE fluorescence-quenching immunochromatographic sensors for the detection of illicit drugs in various complex sample matrices.

Authors: Liu L He G Ye L et al.

Source: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2025 Nov; Vol. 417 (27), pp. 6165-6177. Date of Electronic Publication: 2025 Sep 11.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-2650 (Electronic) Linking ISSN: 16182642 NLM ISO Abbreviation: Anal Bioanal Chem Subsets: MEDLINE

MeSH Terms: Illicit Drugs*/analysis , Illicit Drugs*/urine , Smartphone* , Substance Abuse Detection*/methods , Substance Abuse Detection*/instrumentation , Fluorescence Resonance Energy Transfer*/methods , Fluorescence Resonance Energy Transfer*/instrumentation , Chromatography, Affinity*/instrumentation , Chromatography, Affinity*/methods, Humans ; Limit of Detection ; Gold/chemistry ; Metal Nanoparticles/chemistry ; Methamphetamine/analysis ; Fluorescence

Screening and validation of sponge materials assembled to a sampling device for enrichment and determination of amphetamine drugs in exhaled breath by HPLC-TQ-MS/MS.

Authors: Xu F Zhou J Huang Q et al.

Source: Talanta [Talanta] 2025 Oct 01; Vol. 293, pp. 127994. Date of Electronic Publication: 2025 Mar 20.

Publication Type: Journal Article; Validation Study

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2984816R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3573 (Electronic) Linking ISSN: 00399140 NLM ISO Abbreviation: Talanta Subsets: MEDLINE

MeSH Terms: Amphetamine*/analysis , Substance Abuse Detection*/instrumentation , Substance Abuse Detection*/methods , Amphetamines*/analysis, Tandem Mass Spectrometry/methods ; Chromatography, High Pressure Liquid/methods ; Humans ; Breath Tests/instrumentation ; Breath Tests/methods ; Exhalation ; Adsorption ; Limit of Detection

Development and validation of general urine screening method for performance enhancing drugs in racehorses utilizing liquid chromatography-high resolution mass spectrometry (LC-HRMS).

Authors: Dubey S Lomnicka I Waller P et al.

Source: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2025 Dec 15; Vol. 1267, pp. 124786. Date of Electronic Publication: 2025 Sep 10.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

MeSH Terms: Mass Spectrometry*/methods , Performance-Enhancing Substances*/urine , Doping in Sports* , Substance Abuse Detection*/methods, Horses/urine ; Animals ; Reproducibility of Results ; Chromatography, High Pressure Liquid/methods ; Chromatography, Liquid/methods ; Linear Models ; Sensitivity and Specificity ; Limit of Detection

Multi-residue screening method of 195 drugs of abuse and metabolites in whole blood using LC-MS/MS and application to real blood samples.

Authors: Lee S Lee J Ok H et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Dec 15; Vol. 266, pp. 117096. Date of Electronic Publication: 2025 Aug 08.

Publication Type: Journal Article; Validation Study

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Illicit Drugs*/blood , Illicit Drugs*/metabolism , Substance Abuse Detection*/methods, Humans ; Limit of Detection ; Chromatography, Liquid/methods ; Reproducibility of Results ; Liquid-Liquid Extraction/methods ; Liquid Chromatography-Mass Spectrometry

A Novel and Validated GC-MS/MS Method for the Detection of Four Opioids and Seven Fentanoids in Oral Fluid for Forensic Applications.

Authors: Tittarelli R Filardi D Mineo F et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2025 Nov 20; Vol. 30 (22). Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

MeSH Terms: Gas Chromatography-Mass Spectrometry*/methods , Analgesics, Opioid*/analysis , Saliva*/chemistry , Fentanyl*/analogs & derivatives , Fentanyl*/analysis , Substance Abuse Detection*/methods , Forensic Toxicology*/methods, Humans ; Tandem Mass Spectrometry/methods ; Solid Phase Extraction ; Limit of Detection ; Reproducibility of Results

Comparability of different analytical workflows for steroid esters detection in doping control field.

Authors: Mazzarino M Van Gansbeke W Albertsdóttir AD et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Nov 15; Vol. 265, pp. 117048. Date of Electronic Publication: 2025 Jul 02.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

MeSH Terms: Esters*/blood , Esters*/analysis , Substance Abuse Detection*/methods , Doping in Sports*/prevention & control , Dried Blood Spot Testing*/methods , Dried Blood Spot Testing*/instrumentation , Steroids*/blood, Tandem Mass Spectrometry/methods ; Humans ; Chromatography, Liquid/methods ; Workflow ; Solvents/chemistry ; Limit of Detection

Method Development of Pegmolesatide for Doping Analysis: A Novel Synthetic Erythropoietin-Mimetic Agent.

Authors: Liu L Wang Z Zhao L et al.

Source: Drug testing and analysis [Drug Test Anal] 2025 Nov; Vol. 17 (11), pp. 2210-2219. Date of Electronic Publication: 2025 Jul 17.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 101483449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-7611 (Electronic) Linking ISSN: 19427603 NLM ISO Abbreviation: Drug Test Anal Subsets: MEDLINE

MeSH Terms: Doping in Sports*/prevention & control , Substance Abuse Detection*/methods , Peptides*/analysis , Erythropoietin*, Humans ; Tandem Mass Spectrometry/methods ; Limit of Detection ; Reproducibility of Results ; Chromatography, Liquid/methods

Comprehensive Screening of Multiple Prohibited Substances in Chinese Traditional Patent Medicine by UHPLC-Q-Orbitrap HRMS.

Authors: Fei Q Feng Y Wang J et al.

Source: Drug testing and analysis [Drug Test Anal] 2025 Nov; Vol. 17 (11), pp. 2178-2209. Date of Electronic Publication: 2025 Jul 15.

Publication Type: Journal Article; Validation Study

Journal Info: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 101483449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-7611 (Electronic) Linking ISSN: 19427603 NLM ISO Abbreviation: Drug Test Anal Subsets: MEDLINE

MeSH Terms: Drugs, Chinese Herbal*/analysis , Drugs, Chinese Herbal*/chemistry , Medicine, Chinese Traditional* , Substance Abuse Detection*/methods, Humans ; Chromatography, High Pressure Liquid/methods ; Doping in Sports/prevention & control ; Limit of Detection ; Tandem Mass Spectrometry/methods

The first report from Ankara on the presence of xylazine abuse in blood and urine samples using a validated LC-HRMS method.

Authors: Erol Öztürk Y Yeter O Aslıyüksek H et al.

Source: International journal of legal medicine [Int J Legal Med] 2025 Nov; Vol. 139 (6), pp. 2695-2705. Date of Electronic Publication: 2025 Jul 05.

Publication Type: Journal Article; Validation Study

Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9101456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-1596 (Electronic) Linking ISSN: 09379827 NLM ISO Abbreviation: Int J Legal Med Subsets: MEDLINE

MeSH Terms: Xylazine*/urine , Xylazine*/blood , Xylazine*/analogs & derivatives , Substance Abuse Detection*/methods , Substance-Related Disorders*/epidemiology , Illicit Drugs* , Adrenergic alpha-2 Receptor Agonists*/urine , Adrenergic alpha-2 Receptor Agonists*/blood, Humans ; Chromatography, Liquid ; Mass Spectrometry ; Male ; Female ; Adult ; Limit of Detection ; Forensic Toxicology ; Solid Phase Extraction

Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients.

Authors: Polke M Zapf F Restin T et al.

Source: Drug testing and analysis [Drug Test Anal] 2025 Nov; Vol. 17 (11), pp. 2246-2254. Date of Electronic Publication: 2025 Jul 27.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 101483449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-7611 (Electronic) Linking ISSN: 19427603 NLM ISO Abbreviation: Drug Test Anal Subsets: MEDLINE

MeSH Terms: Hair*/chemistry , Analgesics, Opioid*/analysis , Analgesics, Opioid*/therapeutic use , Analgesics, Opioid*/metabolism , Substance Abuse Detection*/methods, Humans ; Infant, Newborn ; Tandem Mass Spectrometry/methods ; Child ; Infant ; Female ; Chromatography, Liquid/methods ; Child, Preschool ; Male ; Limit of Detection ; Fentanyl/analysis ; Adolescent

A biosensor based on tetrahydroxyborate-bismuth vanadate for early diagnosis towards lncRNA markers in cervical cancer tumors.

Authors: Cong C Liu R Sun Y et al.

Source: Talanta [Talanta] 2025 Nov 01; Vol. 294, pp. 128218. Date of Electronic Publication: 2025 Apr 25.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2984816R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3573 (Electronic) Linking ISSN: 00399140 NLM ISO Abbreviation: Talanta Subsets: MEDLINE

MeSH Terms: Biosensing Techniques*/methods , Uterine Cervical Neoplasms*/diagnosis , Uterine Cervical Neoplasms*/genetics , RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/analysis , Biomarkers, Tumor*/genetics , Biomarkers, Tumor*/analysis , Vanadates*/chemistry , Early Detection of Cancer*/methods , Borates*/chemistry, Humans ; Female ; Limit of Detection ; Electrochemical Techniques

Development and validation of a 'dilute and shoot' LC-MS/MS method in urine suitable for screening and confirmation analyses in a clinical setting.

Authors: Florou D Orfanidis A Boumba VA

Source: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2025 Nov 01; Vol. 1265, pp. 124750. Date of Electronic Publication: 2025 Aug 07.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Substance Abuse Detection*/methods, Humans ; Reproducibility of Results ; Chromatography, Liquid/methods ; Limit of Detection ; Linear Models ; Pharmaceutical Preparations/urine ; Liquid Chromatography-Mass Spectrometry

Portable and wireless DNA nanosensor for early detection of lung cancer using ultrafast synthesis of 1T-MoS 2 /liposome-AuNP modified transducer.

Authors: Imran H Ko M Dharuman V et al.

Source: International journal of biological macromolecules [Int J Biol Macromol] 2025 Nov; Vol. 329 (Pt 2), pp. 147736. Date of Electronic Publication: 2025 Sep 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH Terms: Lung Neoplasms*/diagnosis , Lung Neoplasms*/genetics , Liposomes*/chemistry , Biosensing Techniques*/methods , Gold*/chemistry , Metal Nanoparticles*/chemistry , Molybdenum*/chemistry , Early Detection of Cancer*/methods , Disulfides*/chemistry , DNA*, Humans ; Quaternary Ammonium Compounds/chemistry ; Wireless Technology ; Electrochemical Techniques ; Limit of Detection ; Transducers ; Fatty Acids, Monounsaturated

Ultrasensitive Detection of m ⁶ A-Modified RNA Using CRISPR/Cas12a-Integrated Iontronic Biosensor with Hydrophobized Nanochannels: Toward Early Cancer Diagnosis by Machine Learning.

Authors: Gao Z Yang X Ren X et al.

Source: Analytical chemistry [Anal Chem] 2025 Oct 28; Vol. 97 (42), pp. 23609-23621. Date of Electronic Publication: 2025 Oct 14.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

MeSH Terms: Biosensing Techniques*/methods , Machine Learning* , Adenosine*/analogs & derivatives , Adenosine*/analysis , Adenosine*/chemistry , CRISPR-Cas Systems* , Early Detection of Cancer*/methods , RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/analysis , Neoplasms*/diagnosis, Humans ; Hydrophobic and Hydrophilic Interactions ; Limit of Detection ; Aluminum Oxide/chemistry

Development of an Aptamer/CRISPR-Cas12a-Based Dual-Modal Biosensor for Fusobacterium nucleatum Detection in Non-Invasive Colorectal Cancer Screening.

Authors: Wang X Feng S Chen H et al.

Source: Analytical chemistry [Anal Chem] 2025 Oct 28; Vol. 97 (42), pp. 23360-23369. Date of Electronic Publication: 2025 Oct 13.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

MeSH Terms: Fusobacterium nucleatum*/isolation & purification , Colorectal Neoplasms*/diagnosis , Colorectal Neoplasms*/microbiology , Biosensing Techniques*/methods , CRISPR-Cas Systems* , Aptamers, Nucleotide*/chemistry , Early Detection of Cancer*/methods, Humans ; Feces/microbiology ; Limit of Detection ; Bacterial Proteins ; Endodeoxyribonucleases ; CRISPR-Associated Proteins

Analysis of Methyltestosterone and Testosterone Propionate in Dried Blood Spots After Transdermal Application.

Authors: Miyamoto A Okano M Ota M et al.

Source: Drug testing and analysis [Drug Test Anal] 2025 Oct; Vol. 17 (10), pp. 2045-2053. Date of Electronic Publication: 2025 Jun 05.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 101483449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-7611 (Electronic) Linking ISSN: 19427603 NLM ISO Abbreviation: Drug Test Anal Subsets: MEDLINE

MeSH Terms: Dried Blood Spot Testing*/methods , Testosterone Propionate*/blood , Testosterone Propionate*/administration & dosage , Methyltestosterone*/blood , Methyltestosterone*/administration & dosage , Substance Abuse Detection*/methods, Humans ; Male ; Administration, Cutaneous ; Tandem Mass Spectrometry/methods ; Limit of Detection ; Adult ; Doping in Sports ; Chromatography, Liquid/methods

Novel approach to urinary 11-nor-9-carboxy-delta-9-tetrahydrocannabinol analysis in forensic applications using disposable, graphene-based electrochemical sensor coupled with monolithic micro-solid-phase extraction.

Authors: Ar-Sanork K Kamsong W Woensanthia R et al.

Source: Analytica chimica acta [Anal Chim Acta] 2025 Oct 01; Vol. 1369, pp. 344359. Date of Electronic Publication: 2025 Jun 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4324 (Electronic) Linking ISSN: 00032670 NLM ISO Abbreviation: Anal Chim Acta Subsets: MEDLINE

MeSH Terms: Dronabinol*/urine , Dronabinol*/analogs & derivatives , Dronabinol*/isolation & purification , Graphite*/chemistry , Electrochemical Techniques*/instrumentation , Substance Abuse Detection*/methods , Solid Phase Microextraction*, Humans ; Electrodes ; Limit of Detection ; Solid Phase Extraction