Výsledky vyhledávání - "coding datasets"

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    Figure 5—figure supplement 2. Results of shuffling analysis. ; (A–D) The analysis of Foster and Wilson (2007) and (E–F) a corrected analysis. (A) Spike phases were initially calculated by interpolation between theta peaks, shown as dotted lines. (B) After shuffling the phases of spikes, a new spike time is calculated by interpolation between the nearest two theta troughs (dotted lines) to the original spike, which often generates erroneous spike times. The shuffled spike in this case acquires a small phase jitter, but a large temporal jitter. (C) The unshuffled sequence correlations between cell rank order and spike times. The red line shows the mean correlation. (D) Shuffled sequence correlations remained greater than zero, but were significantly reduced relative to the unshuffled case as in experimental data (Foster and Wilson, 2007). (E) Results of a corrected shuffling procedure applied to simulated independent coding datasets and an experimental dataset (height magnified for comparison). Displayed are the average changes in sequence correlations caused by shuffling for each simulated dataset. In 74% of simulated datasets, there was no significant difference between the original and shuffled distributions. (F) Results of the corrected shuffling procedure when applied to datasets simulated with coordinated assemblies. In 81% of simulated coordinated coding datasets, shuffling significantly changed the distribution of sequence correlations. The experimental dataset was not significantly affected by shuffling (p = 0.28, t-test, 2436 putative sequences).

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