Search Results - "challenge"

Role of human infection challenge studies (HICs) in drug development for respiratory syncytial virus (RSV): systematic review and meta-analysis.

Authors: Kundu P Quinn M Thomas E et al.

Source: EBioMedicine [EBioMedicine] 2025 Jul; Vol. 117, pp. 105765. Date of Electronic Publication: 2025 May 29.

Publication Type: Journal Article; Systematic Review; Meta-Analysis

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

MeSH Terms: Antiviral Agents*/therapeutic use , Antiviral Agents*/pharmacology , Drug Development*/methods , Respiratory Syncytial Virus Infections*/drug therapy , Respiratory Syncytial Virus Infections*/virology , Respiratory Syncytial Virus, Human*/drug effects , Human Challenge Trials as Topic*, Humans ; Viral Load/drug effects

Safety, Efficacy, and Immunogenicity of a Salmonella Paratyphi A Vaccine.

Authors: McCann N Paganotti Vicentine M Ebrahimi N et al.

Corporate Authors: McCann N Paganotti Vicentine M Ebrahimi N et al.

Source: The New England journal of medicine [N Engl J Med] 2025 Oct 30; Vol. 393 (17), pp. 1704-1714.

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial

Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

MeSH Terms: Immunogenicity, Vaccine* , Paratyphoid Fever*/immunology , Paratyphoid Fever*/microbiology , Paratyphoid Fever*/prevention & control , Salmonella paratyphi A*/immunology , Typhoid-Paratyphoid Vaccines*/administration & dosage , Typhoid-Paratyphoid Vaccines*/adverse effects , Typhoid-Paratyphoid Vaccines*/immunology, Adult ; Female ; Humans ; Male ; Young Adult ; Administration, Oral ; Antibodies, Bacterial/blood ; Double-Blind Method ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Vaccine Efficacy ; Vaccines, Attenuated/administration & dosage ; Vaccines, Attenuated/adverse effects ; Vaccines, Attenuated/immunology ; Human Challenge Trials as Topic ; Healthy Volunteers ; Immunoglobulin A/blood ; Immunoglobulin A/immunology ; Immunization, Secondary/adverse effects ; Immunization, Secondary/methods

“Batalla de idiomas”: análisis de prácticas sobre variación hispanoamericana en YouTube

Authors: Panzuto Piccini, Nicolás

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Traducció i Ciències del llenguatge

Thesis Advisors: Cassany, Daniel

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Variación léxica hispanoamericana, YouTube, ELE, Retos, Percepción multifocal, Variació lèxica hispanoamericana, Reptes, Percepció multifocal, Spanish language variation, Spanish as a Foreign Language, Challenge, Multifocal perception

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/694680

Innovative approach for the clinical development of a Chlamydia trachomatis vaccine through a human challenge model in women.

Authors: Cohen CR; Department of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA. Electronic address: craig.cohen@ucsf.edu.

Source: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2025 May; Vol. 154, pp. 107861. Date of Electronic Publication: 2025 Mar 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Canada NLM ID: 9610933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3511 (Electronic) Linking ISSN: 12019712 NLM ISO Abbreviation: Int J Infect Dis Subsets: MEDLINE

MeSH Terms: Bacterial Vaccines*/immunology , Chlamydia Infections*/prevention & control , Chlamydia Infections*/immunology , Chlamydia trachomatis*/immunology , Vaccine Development*/methods, Female ; Humans ; Antibodies, Bacterial/blood ; Antibodies, Bacterial/immunology ; Human Challenge Trials as Topic ; Clinical Trials, Phase II as Topic

Students’ Motivation in Challenge-Based Learning in Higher Engineering Education: A scoping review

Authors: Pantzos, Panagiotis, Doctoral Student Pears, Arnold, Professor Ampadu, Ernest

Source: International Journal of Engineering Pedagogy. 15(6):4-34

Subject Terms: Scoping review, motivation, challenge-based learning, engineering education, learning, Teknik och lärande, Technology and Learning

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-372590
https://doi.org/10.3991/ijep.v15i6.54571

Analysing Student Motivation in Challenge-Based Learning in Higher Engineering Education Using the Self-Determination Theory

Authors: Pantzos, Panagiotis, Doctoral Student Pears, Arnold, Professor Buckley, Jeffrey

Source: Innovations in Pedagogy and Technology. 1(1):27-46

Subject Terms: Challenge-based Learning, Motivation, Self-deteermination Theory, Engineering Education, Qualitative study, Teknik och lärande, Technology and Learning

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-369238
https://doi.org/10.63385/ipt.v1i1.45

Developing Surveys on Questionable Research Practices: Four Challenging Design Problems

Authors: Berggren, Christian Gerdin, Bengt, MD, PhD, professor Karabag, Solmaz Filiz

Source: Journal of Academic Ethics. 23(3):1189-1210

Subject Terms: Questionable Research Practices, QRPs, Normative Environment, Organizational Climate, Survey Development, Design Problems, Problem of Incomplete Coverage, Survey Design Process, Baseline Survey, Pre-testing, Technical Assessment, Cognitive Interviews, Social Desirability, Sensitivity, Organizational Controversiality, Challenge of Nonresponse, Qualitative Research, Quantitative Research

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-566340
https://doi.org/10.1007/s10805-024-09565-0

Entrepreneurial education in a pandemic era: Timeframes, demographics, and the nexus between teaching and experiential learning

Authors: Ghannad, Navid Sörensson, Anna

Source: Industry & higher education. 39(1):8-16

Subject Terms: Entrepreneurial education, class diversity, entrepreneurial challenge, opportunity process, COVID-19, case study

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-53320
https://doi.org/10.1177/09504222241249898

mCaptcha: Replacing Captchas with Rate limiters to Improve Security and Accessibility.

Authors: Manivannan, Aravinth Sethuraman, Sibi Chakkaravarthy Vimala Sudhakaran, Devi Priya

Source: Communications of the ACM. Oct2024, Vol. 67 Issue 10, p70-80. 11p.

Subject Terms: *DATA security, CAPTCHA (Challenge-response test), CACHE memory, DENIAL of service attacks, COMPUTER crime prevention, USER-centered system design, PRIVACY

Food safety evaluation and management approaches in dry-cured meat products

Authors: Austrich i Comas, Anna

Contributors: University/Department: Universitat de Girona. Departament d'Enginyeria Química, Agrària i Tecnologia Agroalimentària

Thesis Advisors: Bover i Cid, Sara, Parés i Oliva, Dolors, Gou i Botó, Pere

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Microbiologia predictiva, Microbiología predictiva, Predictive microbiology, Patògens alimentaris, Patógenos alimentarios, Food pathogens, Embotits de pollastre, Embutidos de pollo, Chicken dry-ferented sausages, Pernil curat, Jamón curado, Dry-cured ham, Processament d'aliments, Procesado de los alimentos, Food processing, Conservació d'aliments, Conservación de los alimentos, Food preservation, Estudis d'inoculació, Estudios de inoculación, Challenge tests, Eines fàcils d'utilitzar, Herramientas fáciles de usar, User-friendly tools

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/691260

Navigating Infrastructural Rivalries in Global Politics: The MCC, the BRI, and Nepal’s Domestic Agency.

Authors: Adhikari, Monalisa Acharya, Anurag

Source: Asian Studies Review. Nov2025, p1-22. 22p.

Subject Terms: *BELT & Road Initiative, *NEPALI people, *INTERNATIONAL economic assistance, *NATIONALISM, *INFRASTRUCTURE (Economics), *REGIONALISM (International organization), *LOBBYING, CHINA-United States relations

Geographic Terms: UNITED States, NEPAL, CHINA

Company/Entity: MILLENNIUM Challenge Corp. (U.S.)

Brown macroalgae (Phaeophyceae) as an alternative and sustainable source of novel antimicrobial compounds to improve food safety

Authors: Rubiño Campoy, Susana

Contributors: University/Department: Universitat de Girona. Departament d'Enginyeria Química, Agrària i Tecnologia Agroalimentària

Thesis Advisors: Hortós Bahí, Maria, Aymerich Calvet, Mª Teresa, Parés i Oliva, Dolors, Institut de Tecnologia Agroalimentària

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Macroalgues brunes, Brown macroalgae, Macroalgas pardas, Phaeophyceae, Potencial antimicrobià, Antimicrobial potential, Potencial antimicrobiano, Compostos bioactius, Bioactive compounds, Compuestos bioactivos, Patògens alimentaris, Foodborne pathogens, Patógenos alimentarios, Challenge test, Formatge fresc, Fresh cheese, Queso fresco

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/689508

Fermentation of sugar kelp (Saccharina latissima): exploring the potential of the kelp's native microbiota as starter culture and the microbiological food safety of fermented products

Authors: Stevant, Pierrick Zioga, Evangelia Sorensen, Jonas Steenholdt et al.

Source: FRONTIERS IN FOOD SCIENCE AND TECHNOLOGY. 4

Subject Terms: processing, preservation, seaweed, macroalgae, lactic acid bacteria, challenge test

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Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-373433
https://doi.org/10.3389/frfst.2024.1490547

Innate immune molecular landscape following controlled human influenza virus infection

Authors: Thistlethwaite, William Vangeti, Sindhu Cheng, Wan-Sze et al.

Source: Cell Reports. 44(10)

Subject Terms: human challenge, influenza, innate immunity, multi-omics, scATAC-seq, scRNA-seq, transcriptomics

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Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-247871
https://doi.org/10.1016/j.celrep.2025.116312

Navigating Global Environmental Challenges: Disciplinarity, Transdisciplinarity, and the Emergence of Mega-Expertise

Authors: Lidskog, Rolf, professor, 1961

Source: Samhällsvetenskaplig expertis roller för transformativ förändring Climate. 13(1)

Subject Terms: expertise, global environmental assessment (GEA), global environmental challenge, IPCC, science–policy interface, science–policy relations, sustainable development goals (SDGs), transdisciplinary, transformative change, Sociologi, Sociology

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-118601
https://doi.org/10.3390/cli13010020

Software engineering team project courses with industrial customers: Students’ insights on challenges and lessons learned

Authors: Nasir, Nayla Usman, Muhammad Börstler, Jürgen, Professor et al.

Source: Journal of Systems and Software. 226

Subject Terms: Challenges, Industrial customers, Lessons learned, Project courses, Software engineering, Team projects, Students, Challenge, Complex programs, Engineering teams, Industrial customer, Lesson learned, Project course, Soft skills, Software industry, Thematic analysis, Sales

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:bth-27696
https://doi.org/10.1016/j.jss.2025.112441

The Surface-Topography Challenge: A Multi-Laboratory Benchmark Study to Advance the Characterization of Topography

Authors: Pradhan, A. Müser, M. H. Miller, N. et al.

Source: Tribology letters. 73(3)

Subject Terms: Surface topography, Roughness metrics, Multi-scale topography, Challenge, Open Science, Machine Elements, Maskinelement

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-114163
https://doi.org/10.1007/s11249-025-02014-y

Maneuvering responsive, tactical, and preventive innovation in an innovation ecosystem to address the grand challenge of organized crime

Authors: Nilsson, Susanne Ritzén, Sofia

Source: Creativity and Innovation Management. 33(2):139-165

Subject Terms: divergence and convergence, grand challenge, hybrid interorganizational structure, inductive study, innovation, innovation ecosystem, innovation process, organized crime

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Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-350327
https://doi.org/10.1111/caim.12570

High Degree of Desensitization After 1 Year of Early-Life Peanut Oral Immunotherapy: Small Children Oral Immunotherapy (SmaChO) Randomized Controlled Trial

Authors: Uhl, Carina Klevebro, Susanna Sverremark-Ekström, Eva et al.

Source: Journal of Allergy and Clinical Immunology. 12(5):1297-1305

Subject Terms: Food allergy, Peanut allergy, Oral immunotherapy, Treatment, Ara h 2, Children, Oral peanut challenge

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Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-232514
https://doi.org/10.1016/j.jaip.2024.02.030

The Meaning of Religion and Spirituality in the Lives of Youth: The Case of Finnish Christian School Students

Authors: Rinne, Emmi Räihä, Pekka Kuusisto, Arniika et al.

Source: Growing up radical Journal of Youth and Theology. 23(1):124-150

Subject Terms: Religion, personal religious worldview, resource, challenge, youth, experience, barn- och ungdomsvetenskap med inriktning mot utbildningsvetenskap, Child and Youth Studies with Focus on Educational Science

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Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-212531
https://doi.org/10.1163/24055093-bja10045