Search Results - "ccf-mtDNA"

Extracellular Vesicle Mitochondrial DNA Levels Are Associated With Chronic Kidney Disease and Mitochondrial Haplogroup in Obese Individuals

Authors: Jaida E. Morgan Nicole Noren Hooten Nicolle A. Mode et al.

Source: J Extracell Biol
Journal of Extracellular Biology, Vol 4, Iss 7, Pp n/a-n/a (2025)

Subject Terms: QH573-671, ancestry, circulating cell‐free mitochondrial DNA, exosomes, ccf‐mtDNA, Cytology, EVs, chronic kidney disease, Research Article

Access URL: https://doaj.org/article/fe273fa884434eb38a157696370c9579

Imeglimin-based therapies improve glycemic control and reduce mitochondrial stress in type 2 diabetes: a prospective cohort study

Authors: Abhishek Satheesan Janardanan Subramonia Kumar Leela Kakithakara Vajravelu et al.

Source: Frontiers in Endocrinology, Vol 16 (2025)

Subject Terms: Imeglimin, type 2 diabetes mellitus, ccf-mtDNA, NLRP3 inflammasome, HbA1c, oral hypoglycemic agents, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2025.1639046/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/3b827bc23f2e4eada875b8db5b60b4bc

Effects of the VIVIFRAIL Exercise Protocol on Circulatory and Intracellular Peripheral Mediators Bridging Mitochondrial Dynamics and Inflammation in Robust and Frail Older People

Authors: Fiona Limanaqi Evelyn Ferri Pasquale Ogno et al.

Source: Aging Cell

Subject Terms: apoptosis, ccf‐mtDNA, cytokines, exercise, inflammaging, mitochondria, mitophagy, peripheral blood cells, Research Article

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40033883
https://hdl.handle.net/2434/1152375
https://doi.org/10.1111/acel.70029

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism

Authors: Christian Deuschle Alexander Balck Jenny Ghelfi et al.

Contributors: Christian Deuschle Alexander Balck Jenny Ghelfi et al.

Source: Brain
Brain 143(10), 3041-3051 (2020). doi:10.1093/brain/awaa246
info:eu-repo/grantAgreement/EC/H2020/668738

Subject Terms: Adult, Male, 0301 basic medicine, Parkinson's disease, Ubiquitin-Protein Ligases, blood [Inflammation], blood [DNA, Mitochondrial], Biochemistry, biophysics & molecular biology [F05] [Life sciences], DNA, Mitochondrial, genetics [Inflammation], 03 medical and health sciences, Parkinsonian Disorders, Humans, blood [Interleukin-6], parkin, ddc:610, Biochimie, biophysique & biologie moléculaire [F05] [Sciences du vivant], Aged, Retrospective Studies, genetics [Ubiquitin-Protein Ligases], Inflammation, 0303 health sciences, blood [Biomarkers], Interleukin-6, PINK1, genetics [Protein Kinases], Original Articles, Middle Aged, IL6, 3. Good health, il6, pink1, parkinson's disease, ccf-mtdna, blood [Parkinsonian Disorders], Cross-Sectional Studies, genetics [Parkinsonian Disorders], Female, ccf-mtDNA, Protein Kinases, Biomarkers

File Description: application/pdf

Access URL: https://academic.oup.com/brain/article-pdf/143/10/3041/34032369/awaa246.pdf
https://pubmed.ncbi.nlm.nih.gov/33029617
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586086/
https://moh-it.pure.elsevier.com/en/publications/mitochondrial-damage-associated-inflammation-highlights-biomarker
https://academic.oup.com/brain/article/143/10/3041/5919102
https://orbilu.uni.lu/handle/10993/44651
https://orbilu.uni.lu/bitstream/10993/44651/1/Borsche2020%20-%20mitochondrial%20damage-associated%20inflammation%20highlights%20biomarkers%20in%20PRKN%20PINK1%20parkinsonism.pdf
https://pubmed.ncbi.nlm.nih.gov/33029617/
https://pub.dzne.de/record/164313
http://orbilu.uni.lu/handle/10993/44651

Association of psychosocial stress and poverty with plasma and extracellular vesicle mitochondrial DNA levels.

Authors: Hunter, Tayla D Noren Hooten, Nicole Maul, Hannah E et al.

Source: Psychoneuroendocrinology ; ISSN:1873-3360 ; Volume:182

Subject Terms: Ccf-mtDNA, Chronic disease, DAMP, Extracellular vesicles, Inflammation, Perceived discrimination, Psychosocial stress, Social determinants of health

Relation: https://doi.org/10.1016/j.psyneuen.2025.107622; https://pubmed.ncbi.nlm.nih.gov/41056622

Availability: https://doi.org/10.1016/j.psyneuen.2025.107622
https://pubmed.ncbi.nlm.nih.gov/41056622

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism

Authors: Borsche, Max Koenig, Inke DELCAMBRE, Sylvie et al.

Source: Brain: a Journal of Neurology (2020-10-08)

Subject Terms: Parkinson’s disease, ccf-mtDNA, IL6, PINK1, parkin, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: info:eu-repo/grantAgreement/EC/H2020/668738; https://doi.org/10.1093/brain/awaa246; FNR9631103 - Modelling Idiopathic Parkinson'S Disease-associated Somatic Variation In Dopaminergic Neurons, 2015 (01/01/2016-31/12/2022) - Anne Grünewald; urn:issn:0006-8950; urn:issn:1460-2156; https://orbilu.uni.lu/handle/10993/44651; info:hdl:10993/44651; info:pmid:25744962; wos:000359655000008

Availability: https://orbilu.uni.lu/handle/10993/44651
https://orbilu.uni.lu/bitstream/10993/44651/1/Borsche2020%20-%20mitochondrial%20damage-associated%20inflammation%20highlights%20biomarkers%20in%20PRKN%20PINK1%20parkinsonism.pdf
https://doi.org/10.1093/NTR/NTV039

Circulating Cell-Free mtDNA Contributes to AIM2 Inflammasome-Mediated Chronic Inflammation in Patients with Type 2 Diabetes

Authors: Jung Hwan Bae Seung Jo Seong Jin Kim et al.

Source: Cells, Vol 8, Iss 4, p 328 (2019)

Subject Terms: ccf-mtDNA, chronic inflammation, AIM2 inflammasome, type 2 diabetes, Cytology, QH573-671

Relation: https://www.mdpi.com/2073-4409/8/4/328; https://doaj.org/toc/2073-4409; https://doaj.org/article/e2c58700ab774dcb892fb9285b9c29b6

Availability: https://doi.org/10.3390/cells8040328
https://doaj.org/article/e2c58700ab774dcb892fb9285b9c29b6

Cellular Stress and Effects on Mitochondrial DNA: An Assessment of Stress Reduction & Protective Effects

Authors: Tiwana, Jasmin Kaur Ritvo, Paul G.

Contributors: Tiwana, Jasmin Kaur Ritvo, Paul G.

Subject Terms: Health sciences, Kinesiology, Circulating cell-free mitochondrial DNA (ccf-mtDNA), Acute psychological stress, Mindfulness meditation, Mood, Randomized controlled trial, Psychobiology, Mitochondrial biomarkers

File Description: application/pdf

Relation: https://hdl.handle.net/10315/43386

Availability: https://hdl.handle.net/10315/43386

Circulating cell-free mtDNA release is associated with the activation of cGAS-STING pathway and inflammation in mitochondrial diseases.

Authors: Zhao, Xutong Yu, Meng Zhao, Yawen et al.

Source: J Neurol ; ISSN:1432-1459 ; Volume:269 ; Issue:9

Subject Terms: Ccf-mtDNA, Inflammation, Mitochondrial diseases, cGAS-STING pathway

Relation: https://doi.org/10.1007/s00415-022-11146-3; https://pubmed.ncbi.nlm.nih.gov/35486214

Availability: https://doi.org/10.1007/s00415-022-11146-3
https://pubmed.ncbi.nlm.nih.gov/35486214

Serbest Mitokondriyal Dna nın Sistemik Dolaşımdaki Rolü Ve Hastalıkların Patogenezine Etkisi

Authors: AYDINOĞLU, Ayşe Tülay MENGEŞ, Evrim Aksu HAYTA, Burcu Balcı

Source: Volume:, Issue: 3 372-379
Acıbadem Üniversitesi Sağlık Bilimleri Dergisi

Subject Terms: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, ccf-mtDNA, systemic circulation, inflammation, sistemik dolaşım, inflamasyon, 3. Good health

File Description: application/pdf

Access URL: http://acibadem.dergisi.org/abstract.php?id=549
https://app.trdizin.gov.tr/makale/TXpnME56ZzNOdz09/serbest-mitokondriyal-dna-nin-sistemik-dolasimdaki-rolu-ve-hastaliklarin-patogenezine-etkisi
http://journal.acibadem.edu.tr/en/download/article-file/1701919
https://dergipark.org.tr/tr/pub/acusaglik/issue/61329/914744

İnflamasyon İle İlişkili Nöromüsküler Hastalıklarda Dolaşımdaki Mitokondriyal DNA'nın Araştırılması ; Investigation of the Circulating Mitochondrial DNA in Inflammation Related Neuromuscular Diseases

Authors: AYDINOĞLU, Ayşe Tülay HAYTA, Burcu Tıbbi Biyoloji

Contributors: AYDINOĞLU, Ayşe Tülay HAYTA, Burcu Tıbbi Biyoloji

Subject Terms: absolut kantitasyon, ccf-mtDNA, inflamasyon, nöromüsküler hastalıklar, absolute quantitation, inflammation, neuromuscular diseases, Konu Başlıkları Listesi::Tıp, Mathematics Subject Classification::Biology and other natural sciences, IEEE Thesaurus Terms::Science - general, ERIC Thesaurus::Science and Technology

File Description: application/pdf

Relation: Aydınoğlu, A.T., İnflamasyon İle İlişkili Nöromüsküler Hastalıklarda Dolaşımdaki Mitokondriyal DNA’nın Araştırılması, Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü Tıbbi Biyoloji Yüksek Lisans Tezi, Ankara, 2019.; http://hdl.handle.net/11655/8587

Availability: http://hdl.handle.net/11655/8587

İnflamasyon ile ilişkili nöromüsküler hastalıklarda dolaşımdaki mitokondriyal DNA'nın araştırılması

Authors: AYDINOĞLU, Ayşe Tülay Hayta, Burcu Tıbbi Biyoloji Anabilim Dalı et al.

Contributors: AYDINOĞLU, Ayşe Tülay Hayta, Burcu Tıbbi Biyoloji Anabilim Dalı et al.

Subject Terms: Inflammation, neuromuscular diseases, DNA, nöromüsküler hastalıklar, Tıbbi Biyoloji, Mitochondria, Neuromuscular diseases, ERIC Thesaurus::Science and Technology, inflammation, Diagnosis, Genetics, IEEE Thesaurus Terms::Science - general, inflamasyon, ccf-mtDNA, absolut kantitasyon, absolute quantitation, Genetik, Mathematics Subject Classification::Biology and other natural sciences, Biology, Konu Başlıkları Listesi::Tıp, Biyoloji, Medical Biology, Biomarkers

File Description: application/pdf

Access URL: https://acikbilim.yok.gov.tr/handle/20.500.12812/490428
http://hdl.handle.net/11655/8587

An examination of psychological stress and its effects on the mitochondrial DNA

Authors: Mirzadeh, Parsa Ritvo, Paul G.

Contributors: Mirzadeh, Parsa Ritvo, Paul G.

Subject Terms: Psychobiology, Physiological psychology, Clinical psychology, Mitochondrial psychobiology, Acute stress, ccf-mtDNA, Mitochondria, Mitochondria energy production, International Affective Picture System (IAPS), Mitochondrial science, Mitochondria physiology, Mitochondria health, Mitochondrial stress, Acute stress and the mitochondria, Mitochondrial DNA

File Description: application/pdf

Relation: https://hdl.handle.net/10315/41723

Availability: https://hdl.handle.net/10315/41723

The Role of Circulating Cell-Free Mitochondrial Dna In Systemic Circulation and Its Effect On Diseases Pathogenesis ; Serbest Mitokondriyal DNA’nın Sistemik Dolaşımdaki Rolü ve Hastalıkların Patogenezine Etkisi

Authors: Aydınoğlu, Ayşe Tülay Mengeş, Evrim Aksu Hayta, Burcu Balcı

Source: Volume: , Issue: 3372-379 ; 1309-470X ; 1309-5994 ; Acıbadem Üniversitesi Sağlık Bilimleri Dergisi

Subject Terms: ccf-mtDNA, systemic circulation, inflammation, sistemik dolaşım, inflamasyon

File Description: application/pdf

Relation: https://dergipark.org.tr/tr/download/article-file/1701919; https://dergipark.org.tr/tr/pub/acusaglik/issue/61329/914744

Availability: https://dergipark.org.tr/tr/pub/acusaglik/issue/61329/914744

Roles of mitochondrial DNA in dynamics of the immune response to COVID-19.

Authors: Mahmoodpoor A Sanaie S Ostadi Z et al.

Source: Gene [Gene] 2022 Aug 20; Vol. 836, pp. 146681. Date of Electronic Publication: 2022 Jun 18.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE

MeSH Terms: COVID-19*/genetics , DNA, Mitochondrial*/genetics , DNA, Mitochondrial*/metabolism, Humans ; Immunity ; Mitochondria/genetics ; Mitochondria/metabolism ; SARS-CoV-2

Mitochondria Can Cross Cell Boundaries: An Overview of the Biological Relevance, Pathophysiological Implications and Therapeutic Perspectives of Intercellular Mitochondrial Transfer.

Authors: Valenti D Vacca RA Moro L et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 02; Vol. 22 (15). Date of Electronic Publication: 2021 Aug 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Mitochondrial Dynamics*, Metabolic Diseases/*physiopathology , Mitochondria/*physiology , Neoplasms/*physiopathology , Neurodegenerative Diseases/*physiopathology, Animals ; Humans ; Metabolic Diseases/therapy ; Neoplasms/therapy

An automated, high-throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasma.

Authors: Ware SA Desai N Lopez M et al.

Source: The Journal of biological chemistry [J Biol Chem] 2020 Nov 13; Vol. 295 (46), pp. 15677-15691. Date of Electronic Publication: 2020 Sep 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

MeSH Terms: Cell Nucleus/*genetics , Cell-Free Nucleic Acids/*blood , DNA, Mitochondrial/*blood , High-Throughput Screening Assays/*methods , Mitochondria/*genetics, Automation ; Cell-Free Nucleic Acids/isolation & purification ; Cell-Free Nucleic Acids/metabolism ; DNA, Mitochondrial/isolation & purification ; DNA, Mitochondrial/metabolism ; Endopeptidase K/metabolism ; Humans ; Magnetics ; Microarray Analysis ; Real-Time Polymerase Chain Reaction ; Temperature

Peripheral biomarkers of mitochondrial dysfunction in adolescents with bipolar disorder.

Authors: Jeong H Dimick MK Sultan A et al.

Source: Journal of psychiatric research [J Psychiatr Res] 2020 Apr; Vol. 123, pp. 187-193. Date of Electronic Publication: 2020 Feb 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0376331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1379 (Electronic) Linking ISSN: 00223956 NLM ISO Abbreviation: J Psychiatr Res Subsets: MEDLINE

MeSH Terms: Bipolar Disorder*, Adolescent ; Adult ; Biomarkers ; DNA, Mitochondrial/genetics ; Humans ; Mitochondria

Predictors of ccf-mtDNA reactivity to acute psychological stress identified using machine learning classifiers: A proof-of-concept.

Authors: Trumpff C Marsland AL Sloan RP et al.

Source: Psychoneuroendocrinology [Psychoneuroendocrinology] 2019 Sep; Vol. 107, pp. 82-92. Date of Electronic Publication: 2019 May 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 7612148 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3360 (Electronic) Linking ISSN: 03064530 NLM ISO Abbreviation: Psychoneuroendocrinology Subsets: MEDLINE

MeSH Terms: Cell-Free Nucleic Acids/*genetics , DNA, Mitochondrial/*genetics , Stress, Psychological/*genetics, Adult ; Cardiovascular System/metabolism ; Case-Control Studies ; Cell-Free Nucleic Acids/blood ; DNA, Mitochondrial/blood ; DNA, Mitochondrial/metabolism ; Female ; Humans ; Machine Learning ; Male ; Middle Aged ; Mitochondria/genetics ; Mitochondria/metabolism ; Mitochondria/pathology ; Proof of Concept Study ; Stress, Psychological/metabolism