Search Results - "brain and muscle arnt-like 1"

Repetitive Transcranial Magnetic Stimulation Alleviates MPTP-Induced Parkinson’s Disease Symptoms by Regulating CaMKII-CREB-BMAL1 Pathway in Mice Model

Authors: Chen D Qian S Qian W et al.

Source: Neuropsychiatr Dis Treat
Neuropsychiatric Disease and Treatment, Vol Volume 20, Pp 1693-1710 (2024)

Subject Terms: brain and muscle arnt-like 1, parkinson's disease, transcranial magnetic stimulation, ca2+/calmodulin-dependent protein kinase, Neurosciences. Biological psychiatry. Neuropsychiatry, Neurology. Diseases of the nervous system, RC346-429, camp-response-element-binding protein, RC321-571, Original Research

Access URL: https://pubmed.ncbi.nlm.nih.gov/39279880
https://doaj.org/article/639e0bed21bf4ff0910eac3dcad80990

Sex Differences and Bmal1/Acetylcholine- or Bmal1/Noradrenaline-Mediated Effects of Blue Light Irradiation on Dextran-Sodium-Sulfate-Induced Ulcerative Colitis Model Mice

Authors: Keiichi Hiramoto Sayaka Kubo Keiko Tsuji et al.

Source: Gastrointestinal Disorders, Vol 6, Iss 3, Pp 720-732 (2024)

Subject Terms: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, noradrenaline, Medicine, RC799-869, clock/brain and muscle arnt-like 1, Diseases of the digestive system. Gastroenterology, blue light, acetylcholine, ulcerative colitis

Access URL: https://doaj.org/article/e31d83b31a784159a66c034bb50baaaa

Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-beta-myoCAF-Dependent Mechanism

Authors: Wu, Jieyu Jing, Xu Du, Qiqiao et al.

Source: Advanced Science. 10(24)

Subject Terms: brain and muscle ARNT-like 1, cancer, circadian clock, fibroblasts, metastasis

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-196061
https://liu.diva-portal.org/smash/get/diva2:1779328/FULLTEXT01.pdf

Decreased Memory and Learning Ability Mediated by Bmal1/M1 Macrophages/Angptl2/Inflammatory Cytokine Pathway in Mice Exposed to Long-Term Blue Light Irradiation

Authors: Keiichi Hiramoto Sayaka Kubo Keiko Tsuji et al.

Source: Curr Issues Mol Biol
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4924-4934 (2024)

Subject Terms: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, arginase-1, QH301-705.5, brain and muscle arnt-like 1, angiopoietin like protein 2, interleukin-6, Communication, inducible nitric oxide synthase, Biology (General), blue light

Access URL: https://pubmed.ncbi.nlm.nih.gov/38785563
https://doaj.org/article/62a1ecd3872648c888643435dd79a462

IRF8 aggravates nonalcoholic fatty liver disease via BMAL1/PPARγ axis

Authors: Xinyue Li Hong Zhang Fan Yu et al.

Source: Genes and Diseases, Vol 12, Iss 3, Pp 101333- (2025)

Subject Terms: Brain and muscle ARNT-Like 1, Hepatic steatosis, Interferon regulatory factor 8, Lipogenesis, Non-alcoholic fatty liver disease, Peroxisome proliferator-activated receptor γ, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304224001302; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/dfa8bbebd1db4eb6b91c854ad0be24d9

Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity

Authors: Vera B. Schrauwen-Hinderling Jan Hansen Frank A.J.L. Scheer et al.

Source: Mol Metab
Molecular Metabolism, Vol 5, Iss 8, Pp 635-645 (2016)
Molecular Metabolism

Subject Terms: 0301 basic medicine, FCCP, type 2 diabetes mellitus, CRY, CLOCK, T2DM, Skeletal muscle, body mass index, brain and muscle ARNT-like 1, BMI, 03 medical and health sciences, RT-QPCR, circadian locomotor output cycles kaput, TCA cycle, Internal medicine, 0303 health sciences, Biological rhythm, Molecular clock, BMAL1, Energy metabolism, respiratory exchange ratio, RC31-1245, Mitochondria, PER, period, RER, NADH, tricarboxylic acid cycle, Oxidative capacity, reduced nicotinamide adenine dinucleotide, carbonyl cyanide-4-trifluoromethoxyphenylhydrazone, Original Article, cryptochrome, Real-Time Quantitative Polymerase Chain Reaction

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/27656401
https://doaj.org/article/9f303dfa6f434cfeb3d0dccd2ca4cb13
https://pubmed.ncbi.nlm.nih.gov/27656401/
https://www.sciencedirect.com/science/article/abs/pii/S2212877816300758
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021670
https://cris.maastrichtuniversity.nl/en/publications/demonstration-of-a-day-night-rhythm-in-human-skeletal-muscle-oxid
https://www.narcis.nl/publication/RecordID/oai%3Acris.maastrichtuniversity.nl%3Apublications%2F1a652e28-4ae8-49c8-88e1-e95aabcb706c
https://core.ac.uk/display/154876558

Bioaminergic Responses in an In Vitro System Studying Human Gut Microbiota–Kiwifruit Interactions

Authors: Shanthi Parkar Carel Jobsis Tania Trower et al.

Source: Microorganisms
Microorganisms, Vol 8, Iss 10, p 1582 (2020)
Volume 8
Issue 10

Subject Terms: SCFAs, 0301 basic medicine, 0303 health sciences, QH301-705.5, gamma-amino butyric acid (GABA), short-chain fatty acids, clock gene, green-fleshed kiwifruit, Article, 3. Good health, 03 medical and health sciences, biogenic amines (BAs), Zespri® Green kiwifruit, Gold3 kiwifruit, gold-fleshed kiwifruit, Biology (General), Zespri® SunGold kiwifruit, Brain and Muscle ARNT-Like 1 (Bmal1)

File Description: application/pdf

Access URL: https://www.mdpi.com/2076-2607/8/10/1582/pdf
https://pubmed.ncbi.nlm.nih.gov/33066564
https://doaj.org/article/4f215a8fac6a460cb0e40585a78ed73f
https://www.mdpi.com/2076-2607/8/10/1582
https://www.ncbi.nlm.nih.gov/pubmed/33066564
https://europepmc.org/article/MED/33066564
https://www.mdpi.com/2076-2607/8/10/1582/pdf
https://pubmed.ncbi.nlm.nih.gov/33066564/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602194

Circadian genes CLOCK and BMAL1 in cancer: mechanistic insights and therapeutic strategies.

Authors: Shen Y Zhao Y Sun X et al.

Source: Journal of Zhejiang University. Science. B [J Zhejiang Univ Sci B] 2025 Oct 20; Vol. 26 (10), pp. 935-948.

Publication Type: Journal Article; Review

Journal Info: Publisher: Zhejiang University Press Country of Publication: China NLM ID: 101236535 Publication Model: Print Cited Medium: Internet ISSN: 1862-1783 (Electronic) Linking ISSN: 16731581 NLM ISO Abbreviation: J Zhejiang Univ Sci B Subsets: MEDLINE

MeSH Terms: ARNTL Transcription Factors*/genetics , ARNTL Transcription Factors*/physiology , Neoplasms*/genetics , Neoplasms*/therapy , CLOCK Proteins*/genetics , CLOCK Proteins*/physiology , Circadian Clocks*/genetics, Humans ; Animals ; Circadian Rhythm/genetics ; Tumor Microenvironment ; Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic

The Core Circadian Clock Factor, Bmal1, Transduces Sex-specific Differences in Both Rhythmic and Nonrhythmic Gene Expression in the Mouse Heart.

Authors: Zhang X Procopio SB Ding H et al.

Source: Function (Oxford, England) [Function (Oxf)] 2025 Feb 12; Vol. 6 (1).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101770668 Publication Model: Print Cited Medium: Internet ISSN: 2633-8823 (Electronic) Linking ISSN: 26338823 NLM ISO Abbreviation: Function (Oxf) Subsets: MEDLINE

MeSH Terms: ARNTL Transcription Factors*/genetics , ARNTL Transcription Factors*/metabolism , Circadian Rhythm*/genetics , Circadian Clocks*/genetics , Gene Expression Regulation* , Myocardium*/metabolism, Animals ; Male ; Female ; Myocytes, Cardiac/metabolism ; Mice ; Sex Characteristics ; Mice, Knockout ; Transcriptome ; Mice, Inbred C57BL ; Sex Factors ; GATA4 Transcription Factor/genetics ; GATA4 Transcription Factor/metabolism ; Homeobox Protein Nkx-2.5/genetics ; Homeobox Protein Nkx-2.5/metabolism ; T-Box Domain Proteins/genetics ; T-Box Domain Proteins/metabolism

Sex differences in the adrenal circadian clock: a role for BMAL1 in the regulation of urinary aldosterone excretion and renal electrolyte balance in mice.

Authors: Costello HM Eikenberry SA Cheng KY et al.

Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2025 Jan 01; Vol. 328 (1), pp. F1-F14. Date of Electronic Publication: 2024 Oct 24.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE

MeSH Terms: ARNTL Transcription Factors*/genetics , ARNTL Transcription Factors*/metabolism , ARNTL Transcription Factors*/deficiency , Aldosterone*/urine , Aldosterone*/metabolism , Aldosterone*/blood , Mice, Knockout* , Adrenal Glands*/metabolism , Kidney*/metabolism , Circadian Clocks*/genetics , Water-Electrolyte Balance*, Animals ; Female ; Male ; Sex Factors ; Circadian Rhythm/physiology ; Diet, Sodium-Restricted ; Mice ; Sex Characteristics ; Renal Elimination ; Mice, Inbred C57BL ; Sodium/urine ; Sodium/metabolism

[Berberine regulates glucose and lipid metabolism via clock-controlled genes to ameliorate insulin resistance of hepatocytes].

Authors: Yan LK Cui C Wang Y et al.

Source: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2024 Dec; Vol. 49 (23), pp. 6368-6377.

Publication Type: English Abstract; Journal Article

Journal Info: Publisher: Zhongguo yao xue hui : Zhongguo Zhong yi yan jiu yuan Zhong yao yan jiu suo Country of Publication: China NLM ID: 8913656 Publication Model: Print Cited Medium: Print ISSN: 1001-5302 (Print) Linking ISSN: 10015302 NLM ISO Abbreviation: Zhongguo Zhong Yao Za Zhi Subsets: MEDLINE

MeSH Terms: Hepatocytes*/metabolism , Hepatocytes*/drug effects , Lipid Metabolism*/drug effects , Glucose*/metabolism , Berberine*/pharmacology , Insulin Resistance* , CLOCK Proteins*/metabolism , CLOCK Proteins*/genetics, Humans ; Hep G2 Cells ; ARNTL Transcription Factors/metabolism ; ARNTL Transcription Factors/genetics

Abnormal circadian rhythms and cell death associated with neutrophil extracellular trap play a role in skin cancer caused by long-term blue light irradiation.

Authors: Hiramoto K Kubo S Tsuji K et al.

Source: Archives of dermatological research [Arch Dermatol Res] 2024 May 17; Vol. 316 (5), pp. 177. Date of Electronic Publication: 2024 May 17.

Publication Type: Letter

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8000462 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-069X (Electronic) Linking ISSN: 03403696 NLM ISO Abbreviation: Arch Dermatol Res Subsets: MEDLINE

MeSH Terms: Skin Neoplasms*/pathology , Skin Neoplasms*/immunology , Skin Neoplasms*/etiology , Extracellular Traps*/immunology , Extracellular Traps*/radiation effects , Extracellular Traps*/metabolism , Circadian Rhythm*/physiology , Circadian Rhythm*/radiation effects , Neutrophils*/immunology , Neutrophils*/radiation effects, Humans ; Light/adverse effects ; Cell Death/radiation effects ; Skin/radiation effects ; Skin/pathology ; Skin/immunology ; Blue Light

Intertwined relationship of dynamin-related protein 1, mitochondrial metabolism and circadian rhythm.

Authors: Latha Laxmi IP Job AT Manickam V et al.

Source: Molecular biology reports [Mol Biol Rep] 2024 Apr 05; Vol. 51 (1), pp. 488. Date of Electronic Publication: 2024 Apr 05.

Publication Type: Journal Article; Review

Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

MeSH Terms: Circadian Rhythm*/genetics , Dynamins*/genetics , Dynamins*/metabolism , Mitochondria*/genetics , Mitochondria*/metabolism, Humans

Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior.

Authors: Costello HM Crislip GR Cheng KY et al.

Source: Function (Oxford, England) [Function (Oxf)] 2023 Jan 09; Vol. 4 (2), pp. zqad001. Date of Electronic Publication: 2023 Jan 09 (Print Publication: 2023).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101770668 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-8823 (Electronic) Linking ISSN: 26338823 NLM ISO Abbreviation: Function (Oxf) Subsets: MEDLINE

MeSH Terms: ARNTL Transcription Factors*/genetics , Blood Pressure* , Circadian Clocks*/genetics , Feeding Behavior*, Animals ; Male ; Mice ; Brain/metabolism ; Corticosterone ; Mice, Knockout

Differences in renal BMAL1 contribution to Na ⁺ homeostasis and blood pressure control in male and female mice.

Authors: Crislip GR Douma LG Masten SH et al.

Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Jun 01; Vol. 318 (6), pp. F1463-F1477. Date of Electronic Publication: 2020 Apr 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE

MeSH Terms: Blood Pressure* , Circadian Rhythm* , Renal Reabsorption*, ARNTL Transcription Factors/*metabolism , Nephrons/*metabolism , Sodium/*metabolism, ARNTL Transcription Factors/deficiency ; ARNTL Transcription Factors/genetics ; Animals ; Female ; Genotype ; Homeostasis ; Kidney Tubules, Collecting/metabolism ; Male ; Mice, Knockout ; Phenotype ; Potassium, Dietary/metabolism ; Sex Factors ; Time Factors

The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1.

Authors: Ullah K Chen S Lu J et al.

Source: The Journal of biological chemistry [J Biol Chem] 2020 Apr 03; Vol. 295 (14), pp. 4696-4708. Date of Electronic Publication: 2020 Feb 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

MeSH Terms: Cellular Senescence*/drug effects, ARNTL Transcription Factors/*metabolism , Ubiquitin-Protein Ligases/*metabolism, ARNTL Transcription Factors/antagonists & inhibitors ; ARNTL Transcription Factors/genetics ; Cell Nucleus/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Cycloheximide/pharmacology ; Down-Regulation ; HEK293 Cells ; Humans ; Hydrogen Peroxide/pharmacology ; Mutagenesis, Site-Directed ; Proteasome Endopeptidase Complex/chemistry ; Proteasome Endopeptidase Complex/metabolism ; Protein Binding ; Proteolysis/drug effects ; RNA Interference ; RNA, Small Interfering ; Tumor Suppressor Protein p53/metabolism ; Ubiquitin-Protein Ligases/antagonists & inhibitors ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination

Icariin promotes osteogenic differentiation of BMSCs by upregulating BMAL1 expression via BMP signaling.

Authors: Huang Z Wei H Wang X et al.

Source: Molecular medicine reports [Mol Med Rep] 2020 Mar; Vol. 21 (3), pp. 1590-1596. Date of Electronic Publication: 2020 Jan 20.

Publication Type: Journal Article

Journal Info: Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-3004 (Electronic) Linking ISSN: 17912997 NLM ISO Abbreviation: Mol Med Rep Subsets: MEDLINE

MeSH Terms: Gene Expression Regulation, Developmental* , Signal Transduction*, ARNTL Transcription Factors/*genetics , Bone Morphogenetic Proteins/*metabolism , Cell Differentiation/*drug effects , Flavonoids/*pharmacology , Mesenchymal Stem Cells/*cytology , Mesenchymal Stem Cells/*drug effects , Osteogenesis/*drug effects, Biomarkers ; Cells, Cultured ; Humans ; Immunophenotyping

BMAL1 and CLOCK proteins in regulating UVB-induced apoptosis and DNA damage responses in human keratinocytes.

Authors: Sun Y Wang P Li H et al.

Source: Journal of cellular physiology [J Cell Physiol] 2018 Dec; Vol. 233 (12), pp. 9563-9574. Date of Electronic Publication: 2018 Jun 26.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4652 (Electronic) Linking ISSN: 00219541 NLM ISO Abbreviation: J Cell Physiol Subsets: MEDLINE

MeSH Terms: DNA Damage* , Ultraviolet Rays*, ARNTL Transcription Factors/*metabolism , Apoptosis/*radiation effects , CLOCK Proteins/*metabolism , Keratinocytes/*metabolism , Keratinocytes/*radiation effects, ARNTL Transcription Factors/genetics ; CLOCK Proteins/genetics ; Cell Differentiation/radiation effects ; Cell Line ; Cell Proliferation/genetics ; Cell Proliferation/radiation effects ; Dose-Response Relationship, Radiation ; Gene Expression Regulation ; Histones/metabolism ; Humans ; Keratinocytes/cytology

Clock genes alterations and endocrine disorders.

Authors: Angelousi A Kassi E Nasiri-Ansari N et al.

Source: European journal of clinical investigation [Eur J Clin Invest] 2018 Jun; Vol. 48 (6), pp. e12927. Date of Electronic Publication: 2018 Apr 16.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0245331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2362 (Electronic) Linking ISSN: 00142972 NLM ISO Abbreviation: Eur J Clin Invest Subsets: MEDLINE

MeSH Terms: Circadian Rhythm Signaling Peptides and Proteins/*genetics , Endocrine System Diseases/*genetics, ARNTL Transcription Factors/genetics ; Adrenal Gland Neoplasms/genetics ; Adrenocortical Adenoma/genetics ; CLOCK Proteins/genetics ; Corticotrophs/metabolism ; Cryptochromes/genetics ; Diabetes Mellitus, Type 1/genetics ; Diabetes Mellitus, Type 2/genetics ; Genetic Predisposition to Disease ; Humans ; Iodide Peroxidase/metabolism ; Lactotrophs/metabolism ; Period Circadian Proteins/genetics ; Polymorphism, Single Nucleotide ; Prolactin/metabolism ; Somatotrophs/metabolism ; Thyroid Diseases/genetics ; Thyroid Diseases/metabolism ; Iodothyronine Deiodinase Type II

How does general anaesthesia affect the circadian clock?

Authors: Poulsen RC Warman GR Sleigh J et al.

Source: Sleep medicine reviews [Sleep Med Rev] 2018 Feb; Vol. 37, pp. 35-44. Date of Electronic Publication: 2016 Dec 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal Info: Publisher: W.B. Saunders Co Country of Publication: England NLM ID: 9804678 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2955 (Electronic) Linking ISSN: 10870792 NLM ISO Abbreviation: Sleep Med Rev Subsets: MEDLINE

MeSH Terms: Anesthesia, General/*adverse effects , Circadian Clocks/*drug effects , Circadian Rhythm/*drug effects, Animals ; Circadian Clocks/physiology ; Circadian Rhythm/physiology ; Humans ; N-Methylaspartate/metabolism ; gamma-Aminobutyric Acid/metabolism