Suchergebnisse - "beta-Thalassemia"

Low rate of red cell alloimmunization among multiply transfused beta-thalassemia major patients in the Wasit province of Iraq.

Autoren: Alshihmani I Abedalelah Faraj S Oodi A et al.

Quelle: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis [Transfus Apher Sci] 2025 Dec; Vol. 64 (6), pp. 104267. Date of Electronic Publication: 2025 Oct 25.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Pergamon Country of Publication: England NLM ID: 101095653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-0502 (Print) Linking ISSN: 14730502 NLM ISO Abbreviation: Transfus Apher Sci Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/therapy , beta-Thalassemia*/blood , beta-Thalassemia*/immunology , Isoantibodies*/blood , Blood Transfusion* , Erythrocytes*/immunology, Humans ; Iraq ; Male ; Female ; Cross-Sectional Studies ; Adult ; Adolescent ; Child ; Young Adult ; Child, Preschool

Evaluation of Immune Functions in Transfusion-Dependent Thalassemia Patients with Alloimmunization

Autoren: Özköteş NÖ Karapınar TH Okur Acar S et al.

Quelle: Turkish journal of haematology : official journal of Turkish Society of Haematology [Turk J Haematol] 2025 Nov 29; Vol. 42 (4), pp. 306-314. Date of Electronic Publication: 2025 Aug 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Galenos Yayinevi Country of Publication: Turkey NLM ID: 9606065 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1308-5263 (Electronic) Linking ISSN: 13007777 NLM ISO Abbreviation: Turk J Haematol Subsets: MEDLINE

MeSH-Schlagworte: Isoantibodies*/blood , Isoantibodies*/immunology , Thalassemia*/therapy , Thalassemia*/immunology , Thalassemia*/blood , Transfusion Reaction*/immunology , beta-Thalassemia*/therapy , beta-Thalassemia*/immunology, Humans ; Child ; Male ; Female ; Adolescent ; Child, Preschool ; Infant ; Young Adult ; Retrospective Studies ; Blood Transfusion ; Adult ; Erythrocyte Transfusion/adverse effects

A standardized extract of Centella asiatica (ECa 233) alleviates brain injury and improves brain function in β-thalassemia mice with iron overload.

Autoren: Yatmark P Anutagerngkun P Huaijantug S et al.

Quelle: BMC complementary medicine and therapies [BMC Complement Med Ther] 2025 Nov 05; Vol. 25 (1), pp. 412. Date of Electronic Publication: 2025 Nov 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101761232 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-7671 (Electronic) Linking ISSN: 26627671 NLM ISO Abbreviation: BMC Complement Med Ther Subsets: MEDLINE

MeSH-Schlagworte: Iron Overload*/drug therapy , Plant Extracts*/pharmacology , Centella* , Triterpenes*/pharmacology , Brain Injuries*/drug therapy , beta-Thalassemia*/complications , beta-Thalassemia*/drug therapy , Neuroprotective Agents*/pharmacology, Animals ; Mice ; Male ; Disease Models, Animal ; Mice, Knockout ; Brain/drug effects

Evaluation of osteoporosis in adult patients with beta-thalassemia major and its relation to serum sclerostin level.

Autoren: Bamby AAEFE El Hamid El Bedawi TA Eltomi MA et al.

Quelle: Clinics and research in hepatology and gastroenterology [Clin Res Hepatol Gastroenterol] 2025 Nov; Vol. 49 (9), pp. 102709. Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Masson Country of Publication: France NLM ID: 101553659 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2210-741X (Electronic) Linking ISSN: 22107401 NLM ISO Abbreviation: Clin Res Hepatol Gastroenterol Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/complications , beta-Thalassemia*/blood , Osteoporosis*/blood , Osteoporosis*/etiology , Osteoporosis*/diagnosis , Bone Morphogenetic Proteins*/blood, Humans ; Adaptor Proteins, Signal Transducing ; Male ; Female ; Cross-Sectional Studies ; Case-Control Studies ; Genetic Markers ; Adult ; Young Adult ; Middle Aged

Coexistence of Hereditary Spherocytosis, Beta-Thalassemia Trait and Gilbert Syndrome in a Newborn: A Rare Genetic Profile.

Autoren: Kapoor S Gupta P

Quelle: Fetal and pediatric pathology [Fetal Pediatr Pathol] 2025 Nov-Dec; Vol. 44 (6), pp. 589-593. Date of Electronic Publication: 2025 Sep 27.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101230972 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-3823 (Electronic) Linking ISSN: 15513815 NLM ISO Abbreviation: Fetal Pediatr Pathol Subsets: MEDLINE

MeSH-Schlagworte: Spherocytosis, Hereditary*/genetics , Spherocytosis, Hereditary*/diagnosis , Spherocytosis, Hereditary*/complications , Gilbert Disease*/genetics , Gilbert Disease*/diagnosis , Gilbert Disease*/complications , beta-Thalassemia*/genetics , beta-Thalassemia*/diagnosis , beta-Thalassemia*/complications, Humans ; Infant, Newborn ; Male ; Glucuronosyltransferase/genetics ; Spectrin

Dietary Patterns Among Patients With Beta-Thalassemia Major in Vietnam.

Autoren: Hoang TNA Quach HL

Quelle: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association [J Hum Nutr Diet] 2025 Oct; Vol. 38 (5), pp. e70120.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley on behalf of The British Dietetic Association Ltd., [c1988- Country of Publication: England NLM ID: 8904840 Publication Model: Print Cited Medium: Internet ISSN: 1365-277X (Electronic) Linking ISSN: 09523871 NLM ISO Abbreviation: J Hum Nutr Diet Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/epidemiology , beta-Thalassemia*/complications , Diet*/statistics & numerical data , Diet*/methods , Feeding Behavior*, Humans ; Vietnam/epidemiology ; Male ; Female ; Adult ; Nutritional Status ; Middle Aged ; Young Adult ; Malnutrition/epidemiology ; Thinness/epidemiology ; Surveys and Questionnaires ; Fast Foods ; Adolescent ; Cross-Sectional Studies ; Noncommunicable Diseases/epidemiology

Efficacy and safety of luspatercept in non-transfusion-dependent β-thalassemia: long-term results from the BEYOND study.

Autoren: Taher AT Viprakasit V Kattamis A et al.

Quelle: Blood advances [Blood Adv] 2025 Dec 09; Vol. 9 (23), pp. 6108-6119.

Publikationsart: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/drug therapy , beta-Thalassemia*/blood , Immunoglobulin Fc Fragments*/therapeutic use , Immunoglobulin Fc Fragments*/adverse effects , Immunoglobulin Fc Fragments*/administration & dosage , Recombinant Fusion Proteins*/therapeutic use , Recombinant Fusion Proteins*/adverse effects , Recombinant Fusion Proteins*/administration & dosage , Activin Receptors, Type II*/therapeutic use , Activin Receptors, Type II*/administration & dosage, Humans ; Male ; Female ; Adult ; Treatment Outcome ; Adolescent ; Young Adult ; Middle Aged ; Double-Blind Method ; Child

Thalassemia and hypercoagulability.

Autoren: Cappellini MD Taher AT Motta I

Quelle: Hematology. American Society of Hematology. Education Program [Hematology Am Soc Hematol Educ Program] 2025 Dec 05; Vol. 2025 (1), pp. 285-290.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 100890099 Publication Model: Print Cited Medium: Internet ISSN: 1520-4383 (Electronic) Linking ISSN: 15204383 NLM ISO Abbreviation: Hematology Am Soc Hematol Educ Program Subsets: MEDLINE

MeSH-Schlagworte: Thrombophilia*/etiology , Thrombophilia*/therapy , Thrombophilia*/blood , Thalassemia*/complications , Thalassemia*/therapy , Thalassemia*/blood , beta-Thalassemia*/complications , beta-Thalassemia*/therapy , beta-Thalassemia*/blood, Humans ; Thrombosis/etiology ; Thrombosis/prevention & control ; Risk Factors ; Splenectomy

Catalog of 73 novel variants in thalassemia: discoveries and insights.

Autoren: Huang J Liu Z Miao F et al.

Quelle: Human molecular genetics [Hum Mol Genet] 2025 Dec 04; Vol. 34 (24), pp. 2067-2074.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/genetics , beta-Thalassemia*/epidemiology , alpha-Thalassemia*/genetics , alpha-Thalassemia*/epidemiology , Genetic Variation* , Thalassemia*/genetics , Thalassemia*/epidemiology, Humans ; Male ; Female ; Adult ; High-Throughput Nucleotide Sequencing ; China/epidemiology ; Genotype ; Adolescent ; Young Adult ; Middle Aged ; Phenotype ; alpha-Globins/genetics ; Child

The disease burden of β-thalassaemia revisited.

Autoren: Soteriades ES Angastiniotis M Economidou EC et al.

Quelle: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2551450. Date of Electronic Publication: 2025 Sep 08.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/epidemiology , beta-Thalassemia*/economics , beta-Thalassemia*/therapy , Cost of Illness*, Humans ; Male ; Female

Clinical patterns of thalidomide in the treatment of transfusion-dependent β-thalassaemia in children: a prospective single-arm study in China.

Autoren: Li X Hong W Wu J et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2561219. Date of Electronic Publication: 2025 Oct 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Thalidomide*/adverse effects , Thalidomide*/therapeutic use , Thalidomide*/administration & dosage , beta-Thalassemia*/therapy , beta-Thalassemia*/drug therapy , Immunosuppressive Agents*/adverse effects , Immunosuppressive Agents*/therapeutic use , Immunosuppressive Agents*/administration & dosage, Humans ; Child ; Male ; Female ; Prospective Studies ; Adolescent ; China ; Child, Preschool ; Blood Transfusion ; Treatment Outcome ; Neural Conduction/drug effects ; Body Height/drug effects

IGHG4: innovative diagnostic biomarkers for iron overload in β-thalassemia patients.

Autoren: Liu Y Huang J Luo J

Quelle: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2433154. Date of Electronic Publication: 2024 Dec 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/blood , beta-Thalassemia*/diagnosis , Biomarkers*/blood , Iron Overload*/diagnosis , Iron Overload*/blood , Iron Overload*/etiology, Humans ; Male ; Female ; Child ; Child, Preschool ; Adolescent

Prevention and control of thalassemia in Guangdong Province, Southern China: insights from an 11-year retrospective study.

Autoren: Qin D He W Wang J et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2548970. Date of Electronic Publication: 2025 Aug 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Prenatal Diagnosis*/methods , beta-Thalassemia*/prevention & control , beta-Thalassemia*/epidemiology , beta-Thalassemia*/genetics , beta-Thalassemia*/diagnosis , alpha-Thalassemia*/prevention & control , alpha-Thalassemia*/epidemiology , alpha-Thalassemia*/genetics , alpha-Thalassemia*/diagnosis , Thalassemia*/prevention & control , Thalassemia*/epidemiology , Thalassemia*/genetics , Thalassemia*/diagnosis, Humans ; China/epidemiology ; Retrospective Studies ; Female ; Pregnancy ; Prevalence ; Genotype ; Mutation ; Adult ; Male

Complex interaction of δ-globin variant HbA 2 -Famagusta combined with β-globin variant Hb Monroe in cis with the HBB:c.-92C>G mutation: hematological characteristics and molecular diagnostic insights.

Autoren: Panyasai S Srisuwan W Sumphanapai T et al.

Quelle: Expert review of hematology [Expert Rev Hematol] 2025 Dec; Vol. 18 (12), pp. 1059-1073. Date of Electronic Publication: 2025 Aug 25.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101485942 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4094 (Electronic) Linking ISSN: 17474094 NLM ISO Abbreviation: Expert Rev Hematol Subsets: MEDLINE

MeSH-Schlagworte: Hemoglobins, Abnormal*/genetics , Hemoglobins, Abnormal*/metabolism , beta-Globins*/genetics , beta-Globins*/metabolism , delta-Globins*/genetics , delta-Globins*/metabolism , Mutation* , beta-Thalassemia*/genetics , beta-Thalassemia*/diagnosis , Hemoglobin A2*/genetics, Humans ; Female ; Aged ; Haplotypes ; Male

Molecular epidemiology and hematological thresholds for αβ-thalassemia: a retrospective cohort study in the Huizhou region of southern China.

Autoren: Chen D Guan Z Huang S et al.

Quelle: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2520075. Date of Electronic Publication: 2025 Jun 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH-Schlagworte: alpha-Thalassemia*/epidemiology , alpha-Thalassemia*/genetics , alpha-Thalassemia*/blood , beta-Thalassemia*/epidemiology , beta-Thalassemia*/genetics , beta-Thalassemia*/blood, Humans ; China/epidemiology ; Female ; Male ; Adult ; Retrospective Studies ; Erythrocyte Indices ; Genotype ; Molecular Epidemiology ; Adolescent ; Middle Aged ; Prevalence ; Child ; Young Adult

A novel 17.9 kb deletion of the beta-globin gene causing beta-thalassemia trait in a Danish male.

Autoren: Kristiansen HP Petersen J Schou P et al.

Quelle: Clinical biochemistry [Clin Biochem] 2025 Dec; Vol. 140, pp. 111035. Date of Electronic Publication: 2025 Oct 30.

Publikationsart: Case Reports; Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0133660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2933 (Electronic) Linking ISSN: 00099120 NLM ISO Abbreviation: Clin Biochem Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/genetics , beta-Thalassemia*/blood , beta-Globins*/genetics , Sequence Deletion* , Gene Deletion*, Humans ; Male ; Middle Aged ; Denmark

Clinical and hematological characteristics of beta-plus thalassemia and uncommon beta-chain hemoglobin variants in Northern Thailand.

Autoren: Rukwong P Natesirinilkul R Sathitsamitphong L et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2551815. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/genetics , beta-Thalassemia*/blood , beta-Thalassemia*/therapy , beta-Thalassemia*/epidemiology , beta-Globins*/genetics , Hemoglobins, Abnormal*/genetics, Humans ; Thailand/epidemiology ; Female ; Male ; Adult ; Retrospective Studies ; Adolescent ; Mutation ; Young Adult ; Child ; Middle Aged ; Hemoglobin E/genetics ; Child, Preschool ; Blood Transfusion

Base editing of β ⁰ -thalassemia mutations as a therapeutic strategy for severe β-hemoglobinopathies.

Autoren: Hardouin G Martinucci P Scaramuzza S et al.

Quelle: Science translational medicine [Sci Transl Med] 2025 Nov 26; Vol. 17 (826), pp. eadt8617. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/genetics , beta-Thalassemia*/therapy , Gene Editing*/methods , Mutation*/genetics , Hemoglobinopathies*/genetics , Hemoglobinopathies*/therapy, Humans ; Animals ; beta-Globins/genetics ; Hematopoietic Stem Cells/metabolism ; Genetic Therapy/methods ; Mice ; Anemia, Sickle Cell/genetics ; Hematopoietic Stem Cell Transplantation

Multi-centric origins and gene flow shape the diversity of β-thalassemia mutations in Southern East Asia.

Autoren: Zhang Q Li J Huang H et al.

Quelle: Nature communications [Nat Commun] 2025 Nov 20; Vol. 16 (1), pp. 10220. Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/genetics , beta-Thalassemia*/epidemiology , Mutation* , beta-Globins*/genetics , Gene Flow*, Humans ; Haplotypes ; China/epidemiology ; Alleles ; Genetic Variation ; Evolution, Molecular ; Hemoglobin E/genetics

Trabecular bone score in the assessment of bone health in thalassemia major.

Autoren: Di Noto M Xourafa A Rosso R et al.

Quelle: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Nov 18; Vol. 16, pp. 1635068. Date of Electronic Publication: 2025 Nov 18 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH-Schlagworte: Cancellous Bone*/diagnostic imaging , Cancellous Bone*/pathology , Bone Density*/physiology , beta-Thalassemia*/complications , beta-Thalassemia*/diagnostic imaging , Osteoporosis*/etiology , Osteoporosis*/diagnostic imaging , Osteoporosis*/diagnosis , Bone Diseases, Metabolic*/etiology , Bone Diseases, Metabolic*/diagnostic imaging, Humans ; Female ; Male ; Adult ; Retrospective Studies ; Absorptiometry, Photon ; Middle Aged ; Lumbar Vertebrae/diagnostic imaging