Výsledky vyhľadávania - "beta Catenin"

Targeting β-catenin preserves gut vascular barrier integrity and attenuates gut-liver axis inflammation in ETEC infection.

Autori: Nie X Feng L Gu X a ďalší

Zdroj: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 16; Vol. 241, pp. 957-969. Date of Electronic Publication: 2025 Oct 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: beta Catenin*/metabolism , beta Catenin*/antagonists & inhibitors , beta Catenin*/genetics , Enterotoxigenic Escherichia coli*/pathogenicity , Escherichia coli Infections*/microbiology , Escherichia coli Infections*/pathology , Escherichia coli Infections*/drug therapy , Escherichia coli Infections*/metabolism, Animals ; Mice ; Swine ; Liver/pathology ; Liver/drug effects ; Liver/metabolism ; Liver/microbiology ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/pathology ; Intestinal Mucosa/microbiology ; Intestinal Mucosa/metabolism ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Wnt Signaling Pathway/drug effects ; Inflammation/microbiology ; Inflammation/pathology ; Male ; Tight Junctions/drug effects ; Tight Junctions/pathology ; Tight Junctions/metabolism ; Diarrhea/microbiology ; Diarrhea/drug therapy ; Diarrhea/pathology ; Disease Models, Animal ; Mice, Inbred C57BL

SM08502-Mediated β-Catenin Repression Synergizes with Olaparib to Inhibit Tumor Progression.

Autori: Corr BR Woodruff ER Yamamoto TM a ďalší

Zdroj: Cancer research communications [Cancer Res Commun] 2025 Dec 01; Vol. 5 (12), pp. 2112-2126.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Phthalazines*/pharmacology , Piperazines*/pharmacology , beta Catenin*/metabolism , beta Catenin*/genetics , beta Catenin*/antagonists & inhibitors , Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/pathology , Ovarian Neoplasms*/metabolism , Antineoplastic Combined Chemotherapy Protocols*/pharmacology, Humans ; Mice ; Animals ; Female ; Drug Synergism ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Xenograft Model Antitumor Assays ; Disease Progression ; Wnt Signaling Pathway/drug effects ; Gene Expression Regulation, Neoplastic/drug effects

Circ_GLS/miR-410-3p/GSK3beta/beta-catenin axis modulates malignant phenotypes of non-small cell lung cancer cells via regulation of cell cycle, apoptosis, ferroptosis, and EMT.

Autori: Wang K Wu Z Lu T a ďalší

Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 334 (Pt 1), pp. 148830. Date of Electronic Publication: 2025 Nov 15.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/metabolism , MicroRNAs*/genetics , MicroRNAs*/metabolism , Glycogen Synthase Kinase 3 beta*/genetics , Glycogen Synthase Kinase 3 beta*/metabolism , Epithelial-Mesenchymal Transition*/genetics , RNA, Circular*/genetics , RNA, Circular*/metabolism , beta Catenin*/metabolism , beta Catenin*/genetics , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/metabolism , Ferroptosis*/genetics, Humans ; Apoptosis/genetics ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Cell Cycle/genetics ; Animals ; Cell Proliferation/genetics ; Mice ; Cell Movement/genetics ; Phenotype

Prostaglandin I 2 signaling restrains Treg cell ST2 expression by repressing β-catenin in allergic airway inflammation.

Autori: Norlander AE Abney M Zhang J a ďalší

Zdroj: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2025 Dec; Vol. 156 (6), pp. 1679-1692.e9. Date of Electronic Publication: 2025 Aug 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: T-Lymphocytes, Regulatory*/immunology , beta Catenin*/immunology , beta Catenin*/genetics , beta Catenin*/metabolism , Epoprostenol*/immunology , Epoprostenol*/metabolism , Interleukin-1 Receptor-Like 1 Protein*/immunology , Interleukin-1 Receptor-Like 1 Protein*/genetics , Interleukin-1 Receptor-Like 1 Protein*/metabolism, Animals ; Signal Transduction/immunology ; Mice ; Mice, Knockout ; Mice, Inbred C57BL

Wnt/β-catenin/ATF3 signaling promotes the progression from acute kidney injury to chronic kidney disease by regulating mitophagy in mice.

Autori: Chen G Zhou Y Lin M a ďalší

Zdroj: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 4), pp. 117444. Date of Electronic Publication: 2025 Oct 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Acute Kidney Injury*/metabolism , Acute Kidney Injury*/pathology , Renal Insufficiency, Chronic*/metabolism , Renal Insufficiency, Chronic*/pathology , Renal Insufficiency, Chronic*/genetics , Mitophagy*/physiology , Activating Transcription Factor 3*/metabolism , Activating Transcription Factor 3*/genetics , Wnt Signaling Pathway*/physiology , Disease Progression* , beta Catenin*/metabolism , beta Catenin*/genetics, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Humans ; Cell Line ; Mitochondrial Dynamics

Targeting Wnt/β-catenin signaling enhances the efficacy of anti-CD38 immunotherapy in multiple myeloma.

Autori: Li H Chen Y Gregorova M a ďalší

Zdroj: Neoplasia (New York, N.Y.) [Neoplasia] 2025 Dec; Vol. 70, pp. 101242. Date of Electronic Publication: 2025 Oct 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5586 (Electronic) Linking ISSN: 14765586 NLM ISO Abbreviation: Neoplasia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Multiple Myeloma*/metabolism , Multiple Myeloma*/drug therapy , Multiple Myeloma*/pathology , Multiple Myeloma*/immunology , Wnt Signaling Pathway*/drug effects , ADP-ribosyl Cyclase 1*/antagonists & inhibitors , ADP-ribosyl Cyclase 1*/immunology , ADP-ribosyl Cyclase 1*/metabolism , Immunotherapy*/methods , beta Catenin*/metabolism , beta Catenin*/genetics , Membrane Glycoproteins*/antagonists & inhibitors , Membrane Glycoproteins*/immunology , Antineoplastic Agents, Immunological*/pharmacology, Humans ; Animals ; Mice ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Antibodies, Monoclonal/pharmacology ; STAT3 Transcription Factor/metabolism ; Disease Models, Animal ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism

Adipocyte-specific IGF1R knockout activates the β-catenin/apelin axis to combat diet-induced obesity in male mice.

Autori: Wang H Mi A Wang X a ďalší

Zdroj: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Dec; Vol. 27 (12), pp. 6927-6942. Date of Electronic Publication: 2025 Sep 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Výrazy zo slovníka MeSH: Obesity*/metabolism , Obesity*/etiology , Obesity*/genetics , Obesity*/prevention & control , beta Catenin*/metabolism , beta Catenin*/genetics , Apelin*/metabolism , Apelin*/genetics , Adipocytes*/metabolism , Receptor, IGF Type 1*/genetics , Receptor, IGF Type 1*/metabolism, Animals ; Male ; Diet, High-Fat/adverse effects ; Mice ; Mice, Knockout ; Signal Transduction ; Mice, Inbred C57BL ; Adipose Tissue/metabolism

S100A16 knockdown reduces RPN2 expression and inhibits β-catenin/TCF signaling, leading to suppressed metastasis in cervical cancer cells.

Autori: Hsin MC Wang PH Chen PN a ďalší

Zdroj: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2025 Dec; Vol. 1872 (8), pp. 120053. Date of Electronic Publication: 2025 Sep 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2596 (Electronic) Linking ISSN: 01674889 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Uterine Cervical Neoplasms*/genetics , Uterine Cervical Neoplasms*/pathology , Uterine Cervical Neoplasms*/metabolism , beta Catenin*/metabolism , beta Catenin*/genetics , Proteasome Endopeptidase Complex*/genetics , Proteasome Endopeptidase Complex*/metabolism , S100 Proteins*/genetics , S100 Proteins*/metabolism , TCF Transcription Factors*/metabolism , TCF Transcription Factors*/genetics, Humans ; Female ; Cell Movement/genetics ; Gene Expression Regulation, Neoplastic ; Signal Transduction ; HeLa Cells ; STAT3 Transcription Factor/metabolism ; STAT3 Transcription Factor/genetics ; Cell Line, Tumor ; Glycogen Synthase Kinase 3 beta/metabolism ; Glycogen Synthase Kinase 3 beta/genetics ; Neoplasm Metastasis ; Gene Knockdown Techniques ; Phosphorylation ; Hexosyltransferases

A novel sulfonamide derivative suppresses gastrointestinal cancer progression by targeting Axin2 and β-catenin.

Autori: Li X Wen H Chang L a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Nov 25; Vol. 15 (1), pp. 41858. Date of Electronic Publication: 2025 Nov 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: beta Catenin*/metabolism , beta Catenin*/chemistry , beta Catenin*/antagonists & inhibitors , Sulfonamides*/pharmacology , Sulfonamides*/chemistry , Gastrointestinal Neoplasms*/drug therapy , Gastrointestinal Neoplasms*/metabolism , Gastrointestinal Neoplasms*/pathology , Axin Protein*/metabolism , Axin Protein*/chemistry , Axin Protein*/antagonists & inhibitors , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry, Humans ; Cell Proliferation/drug effects ; Molecular Docking Simulation ; Cell Line, Tumor ; Wnt Signaling Pathway/drug effects ; Cell Movement/drug effects ; Tubulin/metabolism ; HT29 Cells ; Disease Progression

PDZ domain containing protein 1 aggravates mouse vascular smooth muscle cells calcification via PDZ1 domain mediated β-catenin stabilization and nuclear translocation.

Autori: Li C Yang P Liu X a ďalší

Zdroj: Communications biology [Commun Biol] 2025 Nov 24; Vol. 8 (1), pp. 1642. Date of Electronic Publication: 2025 Nov 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: beta Catenin*/metabolism , beta Catenin*/genetics , Muscle, Smooth, Vascular*/metabolism , Muscle, Smooth, Vascular*/pathology , Muscle, Smooth, Vascular*/cytology , Vascular Calcification*/metabolism , Vascular Calcification*/genetics , Vascular Calcification*/pathology , Myocytes, Smooth Muscle*/metabolism , Myocytes, Smooth Muscle*/pathology, Animals ; Mice ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Membrane Proteins

Huo Xue Tong Luo capsule epigenetically activates β-catenin, promotes Prx1-lineage cells proliferation and endochondral bone formation during fracture healing.

Autori: Peng Y Wang D Zhao Q a ďalší

Zdroj: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2025 Nov 18; Vol. 20 (1), pp. 1007. Date of Electronic Publication: 2025 Nov 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X (Electronic) Linking ISSN: 1749799X NLM ISO Abbreviation: J Orthop Surg Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fracture Healing*/drug effects , Fracture Healing*/genetics , Osteogenesis*/drug effects , Osteogenesis*/genetics , Cell Proliferation*/drug effects , Cell Proliferation*/genetics , beta Catenin*/metabolism , beta Catenin*/genetics , Drugs, Chinese Herbal*/pharmacology , Epigenesis, Genetic*/drug effects , Homeodomain Proteins*/genetics , Homeodomain Proteins*/metabolism , Cell Lineage*/drug effects, Animals ; Mice ; Mesenchymal Stem Cells/drug effects ; Male ; Mice, Inbred C57BL ; Cell Differentiation/drug effects ; Cells, Cultured ; Femoral Fractures/drug therapy

Identification of Novel Phenoxazine-Derived LSD1 Inhibitors Suppressing Gastric Cancer Stemness by β-Catenin Transcriptional Regulation.

Autori: Dai XJ Xue L Liu Y a ďalší

Zdroj: Journal of medicinal chemistry [J Med Chem] 2025 Nov 13; Vol. 68 (21), pp. 22896-22917. Date of Electronic Publication: 2025 Oct 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Histone Demethylases*/antagonists & inhibitors , Histone Demethylases*/metabolism , Stomach Neoplasms*/drug therapy , Stomach Neoplasms*/pathology , Stomach Neoplasms*/metabolism , beta Catenin*/metabolism , beta Catenin*/genetics , Neoplastic Stem Cells*/drug effects , Neoplastic Stem Cells*/metabolism , Neoplastic Stem Cells*/pathology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/therapeutic use , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/therapeutic use , Enzyme Inhibitors*/chemical synthesis , Oxazines*/pharmacology , Oxazines*/chemistry , Oxazines*/chemical synthesis , Oxazines*/therapeutic use, Humans ; Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Mice ; Structure-Activity Relationship ; Transcription, Genetic/drug effects ; Mice, Nude

Disruption of β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction Using Heterogeneous Peptidomimetic Foldamers.

Autori: Sang P Wei J Wu M a ďalší

Zdroj: Journal of the American Chemical Society [J Am Chem Soc] 2025 Nov 12; Vol. 147 (45), pp. 41819-41829. Date of Electronic Publication: 2025 Nov 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

Výrazy zo slovníka MeSH: beta Catenin*/metabolism , beta Catenin*/antagonists & inhibitors , beta Catenin*/chemistry , Peptidomimetics*/chemistry , Peptidomimetics*/pharmacology , Peptidomimetics*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis, Humans ; Cell Proliferation/drug effects ; Cell Line, Tumor ; Protein Binding/drug effects ; Models, Molecular ; Transcription Factors

Vitamin D Ameliorates Doxorubicin-Induced Cognitive Dysfunction via Modulation of the SFRP1/β-Catenin Axis.

Autori: Zhang W Liu Y Pan Y a ďalší

Zdroj: ACS chemical neuroscience [ACS Chem Neurosci] 2025 Nov 05; Vol. 16 (21), pp. 4191-4202. Date of Electronic Publication: 2025 Oct 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Doxorubicin*/toxicity , Vitamin D*/pharmacology , Cognitive Dysfunction*/chemically induced , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/metabolism , beta Catenin*/metabolism , beta Catenin*/drug effects , Neuroprotective Agents*/pharmacology , Membrane Proteins*/metabolism , Intercellular Signaling Peptides and Proteins*/metabolism, Animals ; Mice ; Male ; Oxidative Stress/drug effects ; Hippocampus/drug effects ; Hippocampus/metabolism ; Wnt Signaling Pathway/drug effects ; Antibiotics, Antineoplastic/toxicity ; Mice, Inbred C57BL

β-Catenin-Cohesin Ring-CEGRs/ALCDs Axis Activation Contributes to the Development of Hepatoblastoma and Fibrolamellar HCC.

Autori: Fleifil Y Gulati R Jennings K a ďalší

Zdroj: Molecular cancer research : MCR [Mol Cancer Res] 2025 Nov 03; Vol. 23 (11), pp. 901-912.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: beta Catenin*/metabolism , beta Catenin*/genetics , Hepatoblastoma*/genetics , Hepatoblastoma*/pathology , Hepatoblastoma*/metabolism , Liver Neoplasms*/genetics , Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , Carcinoma, Hepatocellular*/genetics , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics, Humans ; Cohesins ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic

SCR Disease Name: Fibrolamellar hepatocellular carcinoma

Off-pore Nucleoporin sPOM121 Transcriptionally Propels β-Catenin-driven Tumor Progression and Immune Escape in Prostate Cancer.

Autori: Kirthika P Jawalagatti V Li P a ďalší

Zdroj: Cancer discovery [Cancer Discov] 2025 Nov 03; Vol. 15 (11), pp. 2374-2396.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

Výrazy zo slovníka MeSH: Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/immunology , Prostatic Neoplasms*/metabolism , beta Catenin*/metabolism , beta Catenin*/genetics , Nuclear Pore Complex Proteins*/metabolism , Nuclear Pore Complex Proteins*/genetics , Tumor Escape*, Male ; Humans ; Animals ; Mice ; Disease Progression ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic

KDM1A Facilitates Oncogenic Potential in Colorectal Cancer Progression Through the Activation of AXIN/GSK3β/β-Catenin Signaling Pathways: Evidence From Integrated Transcriptomics and In Vitro Studies.

Autori: Natarajan SR Krishnamoorthy R Alshuniaber MA a ďalší

Zdroj: The journal of gene medicine [J Gene Med] 2025 Nov; Vol. 27 (11), pp. e70053.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9815764 Publication Model: Print Cited Medium: Internet ISSN: 1521-2254 (Electronic) Linking ISSN: 1099498X NLM ISO Abbreviation: J Gene Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , Histone Demethylases*/genetics , Histone Demethylases*/metabolism , beta Catenin*/metabolism , beta Catenin*/genetics , Glycogen Synthase Kinase 3 beta*/metabolism , Glycogen Synthase Kinase 3 beta*/genetics, Humans ; Cell Proliferation/drug effects ; Cell Line, Tumor ; Disease Progression ; Gene Expression Regulation, Neoplastic/drug effects ; Wnt Signaling Pathway ; Transcriptome ; Signal Transduction ; Epithelial-Mesenchymal Transition ; Glycolysis

Oncogenic Role of PTPN14 in Pancreatic Cancer Through β-Catenin/NF-κB Pathway Activation.

Autori: Luo D Luo X Qian S a ďalší

Zdroj: IUBMB life [IUBMB Life] 2025 Nov; Vol. 77 (11), pp. e70078.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Published for the International Union of Biochemistry and Molecular Biology by Taylor & Francis Country of Publication: England NLM ID: 100888706 Publication Model: Print Cited Medium: Internet ISSN: 1521-6551 (Electronic) Linking ISSN: 15216543 NLM ISO Abbreviation: IUBMB Life Subsets: MEDLINE

Výrazy zo slovníka MeSH: beta Catenin*/metabolism , beta Catenin*/genetics , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/metabolism , Protein Tyrosine Phosphatases, Non-Receptor*/genetics , Protein Tyrosine Phosphatases, Non-Receptor*/metabolism , NF-kappa B*/metabolism , NF-kappa B*/genetics, Humans ; Animals ; Mice ; Cell Proliferation/genetics ; Signal Transduction ; Apoptosis/genetics ; Gene Expression Regulation, Neoplastic ; Cell Movement/genetics ; Mice, Nude ; Cell Line, Tumor ; Male ; Xenograft Model Antitumor Assays ; Female ; Mice, Inbred BALB C

CKAP4 Promotes Atrial Fibrosis and Enhances Atrial Fibrillation Vulnerability via WNT/β-Catenin Activation.

Autori: Feng Y Chen Z Gao Y a ďalší

Zdroj: Circulation. Arrhythmia and electrophysiology [Circ Arrhythm Electrophysiol] 2025 Nov; Vol. 18 (11), pp. e014217. Date of Electronic Publication: 2025 Oct 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101474365 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-3084 (Electronic) Linking ISSN: 19413084 NLM ISO Abbreviation: Circ Arrhythm Electrophysiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Atrial Fibrillation*/metabolism , Atrial Fibrillation*/physiopathology , Atrial Fibrillation*/genetics , Atrial Fibrillation*/pathology , Heart Atria*/pathology , Heart Atria*/metabolism , Heart Atria*/physiopathology , Wnt Signaling Pathway* , Atrial Remodeling* , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/blood , Cytoskeletal Proteins*/metabolism , beta Catenin*/metabolism, Animals ; Fibrosis ; Humans ; Male ; Rats ; Mice ; Disease Models, Animal ; Female ; Middle Aged ; Mice, Inbred C57BL ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Cells, Cultured ; Case-Control Studies

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β-Catenin Ubiquitination.

Autori: Xu Y Zhang P Xiong Z a ďalší

Zdroj: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Nov; Vol. 12 (44), pp. e04485. Date of Electronic Publication: 2025 Aug 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alternative Splicing*/genetics , beta Catenin*/metabolism , beta Catenin*/genetics , Stem Cells*/metabolism , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/cytology, Ubiquitination/genetics ; Animals ; Mice ; Wnt Signaling Pathway/genetics ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Humans