Suchergebnisse - "aggregation"

Discovery of a novel and potent antiplatelet thiol prodrug CG-0255.

Autoren: Wu H Hou K Chen X et al.

Quelle: European journal of medicinal chemistry [Eur J Med Chem] 2025 Nov 05; Vol. 297, pp. 117973. Date of Electronic Publication: 2025 Jul 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Prodrugs*/pharmacology , Prodrugs*/chemistry , Prodrugs*/chemical synthesis , Prodrugs*/pharmacokinetics , Prodrugs*/administration & dosage , Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/chemistry , Platelet Aggregation Inhibitors*/chemical synthesis , Platelet Aggregation Inhibitors*/pharmacokinetics , Platelet Aggregation Inhibitors*/administration & dosage , Sulfhydryl Compounds*/chemistry , Sulfhydryl Compounds*/pharmacology , Sulfhydryl Compounds*/chemical synthesis , Drug Discovery*, Humans ; Animals ; Molecular Structure ; Structure-Activity Relationship ; Dose-Response Relationship, Drug ; Rats ; Platelet Aggregation/drug effects

Bedtime vs. morning aspirin intake on the diurnal variability of blood pressure and platelet aggregation for the prevention of coronary artery diseases: a systematic review and meta-analysis.

Autoren: Ghazou A El-Haddad M Hasan AA et al.

Quelle: Acta cardiologica [Acta Cardiol] 2025 Oct; Vol. 80 (8), pp. 785-795. Date of Electronic Publication: 2025 Mar 10.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 0370570 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1784-973X (Electronic) Linking ISSN: 00015385 NLM ISO Abbreviation: Acta Cardiol Subsets: MEDLINE

MeSH-Schlagworte: Aspirin*/administration & dosage , Platelet Aggregation*/drug effects , Coronary Artery Disease*/prevention & control , Coronary Artery Disease*/physiopathology , Blood Pressure*/drug effects , Blood Pressure*/physiology , Circadian Rhythm*/physiology , Hypertension*/drug therapy , Hypertension*/physiopathology, Humans ; Platelet Aggregation Inhibitors/administration & dosage ; Randomized Controlled Trials as Topic ; Primary Prevention/methods ; Secondary Prevention/methods

Antiplatelet therapy through inhibition of P2Y12 and phosphodiesterase receptors by novel synthesis 1,3-dicyclohexylpyrimidine-2,4(1H,3H)-dione derivatives with computational evaluation.

Autoren: Elsayed DA Soltan MK Abd-El-Maksoud MA et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 109009. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/chemical synthesis , Platelet Aggregation Inhibitors*/chemistry , Purinergic P2Y Receptor Antagonists*/chemical synthesis , Purinergic P2Y Receptor Antagonists*/chemistry , Purinergic P2Y Receptor Antagonists*/pharmacology , Pyrimidines*/pharmacology , Pyrimidines*/chemistry , Pyrimidines*/chemical synthesis , Receptors, Purinergic P2Y12*/metabolism, Humans ; Cyclic Nucleotide Phosphodiesterases, Type 5/metabolism ; Dose-Response Relationship, Drug ; Molecular Docking Simulation ; Molecular Structure ; Platelet Aggregation/drug effects ; Structure-Activity Relationship

Tetrastigma hemsleyanum polysaccharides as natural inhibitors of platelet thrombosis via GPIIb/IIIa and MAPK pathways.

Autoren: Li K Shen C Xu P et al.

Quelle: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Nov 25; Vol. 148, pp. 157439. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

MeSH-Schlagworte: Thrombosis*/drug therapy , Thrombosis*/chemically induced , Polysaccharides*/pharmacology , Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/antagonists & inhibitors , Platelet Aggregation Inhibitors*/pharmacology , MAP Kinase Signaling System*/drug effects, Animals ; Mice ; Male ; Humans ; Blood Platelets/drug effects ; Carrageenan ; Platelet Activation/drug effects ; Fibrinolytic Agents/pharmacology ; Mice, Inbred C57BL ; Disease Models, Animal ; Platelet Aggregation ; Plant Extracts/pharmacology

NADPH oxidase 2 inhibitor GSK2795039 exerts antiplatelet and antithrombotic activity.

Autoren: Oh EB Kong YJ Kim T et al.

Quelle: Scientific reports [Sci Rep] 2025 Oct 16; Vol. 15 (1), pp. 36270. Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Platelet Aggregation Inhibitors*/pharmacology , NADPH Oxidase 2*/antagonists & inhibitors , Fibrinolytic Agents*/pharmacology , Enzyme Inhibitors*/pharmacology, Humans ; Reactive Oxygen Species/metabolism ; Animals ; Platelet Aggregation/drug effects ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Signal Transduction/drug effects ; Phosphorylation/drug effects ; Platelet Activation/drug effects ; Collagen/pharmacology ; Phosphoproteins/metabolism ; Thrombosis/drug therapy ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism

Comparative study of four platelet function tests conducted using two systems in neuroendovascular patients.

Autoren: Sakayori T Nakanishi R Shoda K et al.

Quelle: Scientific reports [Sci Rep] 2025 Sep 29; Vol. 15 (1), pp. 33437. Date of Electronic Publication: 2025 Sep 29.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Platelet Function Tests*/methods , Platelet Aggregation Inhibitors*/therapeutic use , Platelet Aggregation Inhibitors*/pharmacology , Endovascular Procedures* , Blood Platelets*/drug effects, Humans ; Male ; Female ; Aged ; Middle Aged ; Platelet Aggregation/drug effects ; Aged, 80 and over ; Adult ; Retrospective Studies ; Adenosine Diphosphate/pharmacology ; Purinergic P2Y Receptor Antagonists/pharmacology ; Purinergic P2Y Receptor Antagonists/therapeutic use

Design and Synthesis of Edaravone Derivatives Containing 6-(4-aminophenyl)-4,5-dihydropyridazin-3(2H)-one as Bifunctional Anti-ischemic Stroke Agents.

Autoren: Li Y Cai T Fan L et al.

Quelle: Chemistry & biodiversity [Chem Biodivers] 2025 Sep; Vol. 22 (9), pp. e202500516. Date of Electronic Publication: 2025 May 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

MeSH-Schlagworte: Edaravone*/chemical synthesis , Edaravone*/pharmacology , Edaravone*/chemistry , Drug Design* , Platelet Aggregation Inhibitors*/chemical synthesis , Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/chemistry , Platelet Aggregation Inhibitors*/therapeutic use , Neuroprotective Agents*/chemical synthesis , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/chemistry , Neuroprotective Agents*/therapeutic use , Ischemic Stroke*/drug therapy, Animals ; Rats ; PC12 Cells ; Male ; Structure-Activity Relationship ; Rats, Sprague-Dawley ; Molecular Structure ; Molecular Docking Simulation ; Dose-Response Relationship, Drug ; Hydrogen Peroxide/antagonists & inhibitors ; Platelet Aggregation/drug effects

UPLC-QTOF-MS-Based Quantification and Antiplatelet Activity Evaluation of Herb Pair Interactions Between Red Ginseng and Trogopterus Feces.

Autoren: Wu R Wu S Zeng H et al.

Quelle: Chemistry & biodiversity [Chem Biodivers] 2025 Sep; Vol. 22 (9), pp. e202500770. Date of Electronic Publication: 2025 May 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

MeSH-Schlagworte: Panax*/chemistry , Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/chemistry , Platelet Aggregation Inhibitors*/isolation & purification , Feces*/chemistry , Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/chemistry , Ranunculaceae*/chemistry, Chromatography, High Pressure Liquid ; Animals ; Platelet Aggregation/drug effects ; Mass Spectrometry ; Ginsenosides/pharmacology ; Ginsenosides/analysis ; Humans

Anti-Inflammatory and Antiplatelet Interactions on PAF and ADP Pathways of NSAIDs, Analgesic and Antihypertensive Drugs for Cardioprotection-In Vitro Assessment in Human Platelets.

Autoren: Katsanopoulou M Zannas Z Ofrydopoulou A et al.

Quelle: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2025 Aug 04; Vol. 61 (8). Date of Electronic Publication: 2025 Aug 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE

MeSH-Schlagworte: Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal*/pharmacology , Anti-Inflammatory Agents, Non-Steroidal*/therapeutic use , Platelet Activating Factor*/analysis , Platelet Activating Factor*/drug effects , Platelet Activating Factor*/metabolism , Adenosine Diphosphate* , Blood Platelets*/drug effects , Antihypertensive Agents*/pharmacology , Antihypertensive Agents*/therapeutic use , Analgesics*/pharmacology , Analgesics*/therapeutic use , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/therapeutic use, Humans ; Clopidogrel/pharmacology ; Clopidogrel/therapeutic use ; Platelet Aggregation/drug effects ; Drug Interactions ; Cardiotonic Agents/pharmacology ; Cardiotonic Agents/therapeutic use

New dammarane-type triterpenoids from the whole plant of Euphorbia hypericifolia .

Autoren: Xu M Liu J Sun W et al.

Quelle: Natural product research [Nat Prod Res] 2025 Jul; Vol. 39 (13), pp. 3846-3851. Date of Electronic Publication: 2024 Feb 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE

MeSH-Schlagworte: Euphorbia*/chemistry , Triterpenes*/chemistry , Triterpenes*/isolation & purification , Triterpenes*/pharmacology , Platelet Aggregation Inhibitors*/chemistry , Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/isolation & purification, Dammaranes ; Molecular Structure ; Platelet Aggregation/drug effects ; Magnetic Resonance Spectroscopy

Design, synthesis, and biological evaluation of Pamicogrel derivatives as potential antiplatelet agents.

Autoren: Yuan L Chu QR Li FX et al.

Quelle: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2025 Jul 01; Vol. 122, pp. 130185. Date of Electronic Publication: 2025 Mar 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

MeSH-Schlagworte: Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/chemical synthesis , Platelet Aggregation Inhibitors*/chemistry , Drug Design*, Platelet Aggregation/drug effects ; Structure-Activity Relationship ; Humans ; Molecular Structure ; Arachidonic Acid/pharmacology ; Dose-Response Relationship, Drug ; Adenosine Diphosphate/pharmacology

Integrative pharmacogenomics analysis predicts the platelet response in clopidogrel treated coronary artery disease (CAD) patients of South India.

Autoren: Bharath G Preethi L Suriyam Nagappan A et al.

Quelle: Scientific reports [Sci Rep] 2025 Sep 30; Vol. 15 (1), pp. 33765. Date of Electronic Publication: 2025 Sep 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Coronary Artery Disease*/drug therapy , Coronary Artery Disease*/genetics , Platelet Aggregation Inhibitors*/therapeutic use , Platelet Aggregation Inhibitors*/pharmacology , Blood Platelets*/drug effects , Blood Platelets*/metabolism , Ticlopidine*/analogs & derivatives , Ticlopidine*/therapeutic use , Ticlopidine*/pharmacology, Humans ; Clopidogrel ; Cytochrome P-450 CYP2C19/genetics ; Female ; Male ; India ; Middle Aged ; Pharmacogenetics/methods ; Aged ; Aryldialkylphosphatase/genetics ; Genotype ; Platelet Function Tests ; Polymorphism, Single Nucleotide ; Drug Resistance/genetics ; Platelet Aggregation/drug effects ; Phenotype

Ammonium Catecholaldehydes as Multifunctional Bioactive Agents: Evaluating Antimicrobial, Antioxidant, and Antiplatelet Activity.

Autoren: Bogdanov AV Tagasheva RG Voloshina A et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Aug 14; Vol. 26 (16). Date of Electronic Publication: 2025 Aug 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Antioxidants*/pharmacology , Antioxidants*/chemistry , Antioxidants*/chemical synthesis , Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/chemistry , Platelet Aggregation Inhibitors*/chemical synthesis , Catechols*/chemistry , Catechols*/pharmacology , Aldehydes*/chemistry , Aldehydes*/pharmacology , Anti-Infective Agents*/pharmacology , Anti-Infective Agents*/chemistry , Quaternary Ammonium Compounds*/chemistry , Quaternary Ammonium Compounds*/pharmacology , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry, Humans ; Microbial Sensitivity Tests ; Platelet Aggregation/drug effects ; Animals ; Hydrazones/chemistry ; Hydrazones/pharmacology

Tirofiban protects mice against severe RSV pneumonia by potentially inhibiting platelet activation via the GPIbα-vWF pathway.

Autoren: Luo YS Shen H Ling P et al.

Quelle: Antiviral research [Antiviral Res] 2025 Aug; Vol. 240, pp. 106207. Date of Electronic Publication: 2025 Jun 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE

MeSH-Schlagworte: Tirofiban*/pharmacology , Platelet Activation*/drug effects , Platelet Glycoprotein GPIb-IX Complex*/metabolism , Respiratory Syncytial Virus Infections*/drug therapy , Respiratory Syncytial Virus Infections*/prevention & control , Respiratory Syncytial Virus Infections*/virology , Platelet Aggregation Inhibitors*/pharmacology , Pneumonia, Viral*/prevention & control , Pneumonia, Viral*/drug therapy, Animals ; Mice ; Platelet Aggregation/drug effects ; Signal Transduction/drug effects ; Lung/pathology ; Lung/virology ; Disease Models, Animal ; Blood Platelets/drug effects ; Female ; Mice, Inbred BALB C ; Respiratory Syncytial Viruses/drug effects

Novel Coumarin-Hydrazone Hybrids as Potential Antiplatelet Agents: Microwave-Assisted Synthesis, Characterization, In Vitro and In Silico Biological Evaluations and Toxicity Assessment.

Autoren: Khdhiri E Haffouz A HadjKacem B et al.

Quelle: Chemistry & biodiversity [Chem Biodivers] 2025 Aug; Vol. 22 (8), pp. e202500101. Date of Electronic Publication: 2025 Apr 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

MeSH-Schlagworte: Coumarins*/chemistry , Coumarins*/pharmacology , Coumarins*/chemical synthesis , Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/chemical synthesis , Platelet Aggregation Inhibitors*/chemistry , Hydrazones*/chemistry , Hydrazones*/pharmacology , Hydrazones*/chemical synthesis , Microwaves*, Platelet Aggregation/drug effects ; Humans ; Molecular Docking Simulation ; Structure-Activity Relationship ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Molecular Structure ; Dose-Response Relationship, Drug ; Receptors, Purinergic P2Y12/metabolism ; Arachidonic Acid/pharmacology ; Arachidonic Acid/antagonists & inhibitors

Platelet-Related Biomarkers and Efficacy of Antiplatelet Therapy in Patients with Aortic Stenosis and Coronary Artery Disease.

Autoren: Bańka P Czepczor K Podolski M et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 23; Vol. 26 (15). Date of Electronic Publication: 2025 Jul 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Biomarkers*/blood , Platelet Aggregation Inhibitors*/therapeutic use , Platelet Aggregation Inhibitors*/pharmacology , Coronary Artery Disease*/drug therapy , Coronary Artery Disease*/blood , Aortic Valve Stenosis*/drug therapy , Aortic Valve Stenosis*/blood , Aortic Valve Stenosis*/complications , Blood Platelets*/metabolism , Blood Platelets*/drug effects, Humans ; Male ; Female ; Aged ; Middle Aged ; P-Selectin/blood ; Aspirin/therapeutic use ; CD40 Ligand/blood ; Thrombomodulin/blood ; Platelet Factor 4/blood ; Platelet Aggregation/drug effects

The soluble guanylate cyclase (sGC) stimulator vericiguat inhibits platelet activation and thrombosis.

Autoren: Zhou W Zhou L Qi Z et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Jul 15; Vol. 999, pp. 177670. Date of Electronic Publication: 2025 Apr 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Soluble Guanylyl Cyclase*/metabolism , Thrombosis*/drug therapy , Thrombosis*/metabolism , Thrombosis*/blood , Thrombosis*/pathology , Platelet Activation*/drug effects , Pyrimidines*/pharmacology , Pyrimidines*/therapeutic use , Platelet Aggregation Inhibitors*/pharmacology , Platelet Aggregation Inhibitors*/therapeutic use, Animals ; Humans ; Mice ; Platelet Aggregation/drug effects ; Male ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Cyclic GMP/metabolism ; Mice, Inbred C57BL ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism ; Heterocyclic Compounds, 2-Ring

Leucophyllusins A-H: new abietane, pimarane, and ent-kaurane diterpenoids from Isodon leucophyllus.

Autoren: Tian SY Hu K Sun HD et al.

Quelle: Fitoterapia [Fitoterapia] 2025 Jul; Vol. 184, pp. 106656. Date of Electronic Publication: 2025 Jun 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

MeSH-Schlagworte: Abietanes*/isolation & purification , Abietanes*/pharmacology , Abietanes*/chemistry , Isodon*/chemistry , Diterpenes, Kaurane*/isolation & purification , Diterpenes, Kaurane*/pharmacology , Diterpenes, Kaurane*/chemistry , Platelet Aggregation Inhibitors*/isolation & purification , Platelet Aggregation Inhibitors*/pharmacology, RAW 264.7 Cells ; Mice ; Animals ; Molecular Structure ; Nitric Oxide/metabolism ; Plant Components, Aerial/chemistry ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; China ; Platelet Aggregation/drug effects

The use of ticagrelor with clopidogrel in patients after interventional therapy for acutely coronary syndrome and effect on serum specificity indices.

Autoren: Chen Y Lei L Ji Q

Quelle: Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2025 Jul-Aug; Vol. 38 (4), pp. 1203-1212.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Faculty of Pharmacy, University of Karachi Country of Publication: Pakistan NLM ID: 9426356 Publication Model: Print Cited Medium: Internet ISSN: 1011-601X (Print) Linking ISSN: 1011601X NLM ISO Abbreviation: Pak J Pharm Sci Subsets: MEDLINE

MeSH-Schlagworte: Ticagrelor*/therapeutic use , Ticagrelor*/adverse effects , Clopidogrel*/therapeutic use , Clopidogrel*/adverse effects , Acute Coronary Syndrome*/drug therapy , Acute Coronary Syndrome*/blood , Acute Coronary Syndrome*/physiopathology , Platelet Aggregation Inhibitors*/therapeutic use , Platelet Aggregation Inhibitors*/adverse effects, Humans ; Male ; Female ; Middle Aged ; Aged ; Biomarkers/blood ; Treatment Outcome ; Platelet Aggregation/drug effects ; Drug Therapy, Combination ; Percutaneous Coronary Intervention/adverse effects

Platelet-leukocyte aggregates in cardiovascular disease: prognostic significance and therapeutic potential.

Autoren: Han J Bloxham CJ Kirmes K et al.

Quelle: Cardiovascular research [Cardiovasc Res] 2025 Sep 29; Vol. 121 (11), pp. 1679-1696.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

MeSH-Schlagworte: Blood Platelets*/metabolism , Blood Platelets*/drug effects , Blood Platelets*/immunology , Blood Platelets*/pathology , Cardiovascular Diseases*/blood , Cardiovascular Diseases*/drug therapy , Cardiovascular Diseases*/immunology , Cardiovascular Diseases*/diagnosis , Leukocytes*/metabolism , Leukocytes*/drug effects , Leukocytes*/immunology , Platelet Aggregation*/drug effects, Humans ; Animals ; Platelet Aggregation Inhibitors/therapeutic use ; Prognosis ; P-Selectin/metabolism ; P-Selectin/blood ; Platelet Activation/drug effects