Suchergebnisse - "Zebrafish Proteins/genetics"

Specificity in clustering of gene-specific transcription factors is encoded in the genome

Autoren: Shivali Dongre Nadine L Vastenhouw

Quelle: Nucleic Acids Res
Nucleic acids research, vol. 53, no. 13

Schlagwörter: Gene regulation, Chromatin and Epigenetics, Animals, Zebrafish/genetics, Zebrafish/embryology, Zebrafish/metabolism, Transcription Factors/genetics, Transcription Factors/metabolism, Transcription Factors/chemistry, Zebrafish Proteins/genetics, Zebrafish Proteins/metabolism, Zebrafish Proteins/chemistry, Genome, Multigene Family, Octamer Transcription Factor-3/genetics, Octamer Transcription Factor-3/metabolism, Octamer Transcription Factor-3/chemistry, Nanog Homeobox Protein/genetics, Nanog Homeobox Protein/metabolism, Intrinsically Disordered Proteins/metabolism, Intrinsically Disordered Proteins/genetics, DNA/metabolism, Embryo, Nonmammalian/metabolism

Dateibeschreibung: application/pdf

Zugangs-URL: https://serval.unil.ch/notice/serval:BIB_4CD68E481E64
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4CD68E481E641
https://serval.unil.ch/resource/serval:BIB_4CD68E481E64.P001/REF.pdf

Oscillatory DeltaC Expression in Neural Progenitors Primes the Prototype of Forebrain Development

Autoren: Nian, Fang-Shin Liao, Bo-Kai Su, Yen-Lin et al.

Quelle: Mol Neurobiol

Schlagwörter: Oscillation pattern, Receptors, Notch/metabolism, Zebrafish Proteins/metabolism, Neurogenesis, Neuroscience (miscellaneous), Forebrain development, Genetics & genetic processes, Prosencephalon/metabolism, Zebrafish/genetics, Cellular and Molecular Neuroscience, Génétique & processus génétiques, Prosencephalon, Neural Stem Cells, Zebrafish/metabolism, Zebrafish Proteins/genetics, Animals, Membrane Proteins/genetics, Notch signaling, Zebrafish, Receptors, Notch, Intracellular Signaling Peptides and Proteins, Prosencephalon/embryology, Gene Expression Regulation, Developmental, Membrane Proteins, Cell Differentiation, Zebrafish Proteins, Life sciences, Delta gene, Neurology, Sciences du vivant, Membrane Proteins/metabolism, Original Article, Neural Stem Cells/metabolism, Signal Transduction

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39392541

FLT4 causes developmental disorders of the cardiovascular and lymphovascular systems via pleiotropic molecular mechanisms

Autoren: Richard M Monaghan Richard W Naylor Daisy Flatman et al.

Quelle: Cardiovasc Res
Monaghan, R M, Naylor, R W, Flatman, D, Kasher, P R, Williams, S G & Keavney, B D 2024, 'FLT4 causes developmental disorders of the cardiovascular and lymphovascular systems via pleiotropic molecular mechanisms', Cardiovascular research, vol. 120, no. 10, cvae104, pp. 1164-1176. https://doi.org/10.1093/cvr/cvae104

Schlagwörter: 0301 basic medicine, Cells, Endothelial Cells/metabolism, Endoplasmic Reticulum, Zebrafish/genetics, 03 medical and health sciences, Primary lymphoedema, Zebrafish Proteins/genetics, Human Umbilical Vein Endothelial Cells, Animals, Humans, Developmental, Genetic Predisposition to Disease, Vascular Endothelial Growth Factor Receptor-3/metabolism, Lymphedema, FLT4, Human Umbilical Vein Endothelial Cells/metabolism, Endoplasmic Reticulum/metabolism, Cells, Cultured, Zebrafish, Congenital heart disease, 0303 health sciences, Cultured, Endothelial Cells, Gene Expression Regulation, Developmental, Tetralogy of Fallot/genetics, Zebrafish Proteins, Vascular Endothelial Growth Factor Receptor-3, 3. Good health, Phenotype, Gene Expression Regulation, Mutation, Proteostasis, Tetralogy of Fallot, Original Article, Developmental pleiotropy, VEGFR3, Lymphedema/genetics, Signal Transduction

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38713105
https://research.manchester.ac.uk/en/publications/8c40ed3a-6c44-44cc-856f-46aef161c8b3
https://doi.org/10.1093/cvr/cvae104
https://research.manchester.ac.uk/en/publications/8c40ed3a-6c44-44cc-856f-46aef161c8b3
http://www.scopus.com/inward/record.url?scp=85200464249&partnerID=8YFLogxK
https://doi.org/10.1093/cvr/cvae104

Oscillatory DeltaC Expression in Neural Progenitors Primes the Prototype of Forebrain Development.

Autoren: Nian, Fang-Shin Liao, Bo-Kai Su, Yen-Lin et al.

Quelle: Molecular Neurobiology, 62 (4), 4076 - 4092 (2025-04)

Schlagwörter: Delta gene, Forebrain development, Notch signaling, Oscillation pattern, Zebrafish Proteins, Receptors, Notch, Membrane Proteins, Animals, Signal Transduction, Cell Differentiation, Membrane Proteins/metabolism, Membrane Proteins/genetics, Zebrafish/genetics, Zebrafish/metabolism, Prosencephalon/metabolism, Prosencephalon/embryology, Zebrafish Proteins/metabolism, Zebrafish Proteins/genetics, Gene Expression Regulation, Developmental, Neural Stem Cells/metabolism, Receptors, Notch/metabolism, Neurogenesis, Neural Stem Cells, Prosencephalon, Zebrafish, Neuroscience (miscellaneous), Neurology, Cellular and Molecular Neuroscience, Life sciences, Genetics & genetic processes, Sciences du vivant, Génétique & processus génétiques

Relation: https://link.springer.com/content/pdf/10.1007/s12035-024-04530-9.pdf; urn:issn:0893-7648; urn:issn:1559-1182

Zugangs-URL: https://orbi.uliege.be/handle/2268/330644

HB‐EGF promotes progenitor cell proliferation and sensory neuron regeneration in the zebrafish olfactory epithelium

Autoren: Siran Sireci Yigit Kocagöz Aysu Sevval Alkiraz et al.

Quelle: The FEBS Journal. 291:2098-2133

Schlagwörter: Neurogenesis, olfactory system, tissue regeneration, Olfactory Receptor Neurons, Cell Proliferation -- drug effects, Neurogenesis -- drug effects, Olfactory Mucosa, stem cells, Zebrafish Proteins -- genetics -- metabolism, Olfactory Receptor Neurons -- metabolism -- drug effects -- cytology, Animals, Heparin-binding EGF-like Growth Factor -- genetics -- metabolism, Zebrafish, Cell Proliferation, Olfactory Mucosa -- metabolism -- cytology -- drug effects, Stem Cells, ErbB Receptors -- metabolism -- genetics, Sciences bio-médicales et agricoles, Zebrafish Proteins, Intercellular Signaling Peptides and Proteins -- genetics -- metabolism -- pharmacology, Nerve Regeneration, ErbB Receptors, neurogenesis, Nerve Regeneration -- drug effects, Intercellular Signaling Peptides and Proteins, signaling, Stem Cells -- metabolism -- drug effects -- cytology, Heparin-binding EGF-like Growth Factor, Signal Transduction

Dateibeschreibung: 1 full-text file(s): application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38088047

Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons

Autoren: Shojaeinia, Elham Mastracci, Teresa L. Soliman, Remon et al.

Weitere Verfasser: Shojaeinia, Elham Mastracci, Teresa L. Soliman, Remon et al.

Quelle: Mol Brain
Molecular Brain, Vol 17, Iss 1, Pp 1-10 (2024)

Schlagwörter: Oxidoreductases Acting on CH-NH Group Donors, Epilepsy, Deoxyhypusine synthase, Short Report, Brain, Zebrafish Proteins, Hypusine, Disease Models, Animal, Phenotype, Neurodevelopmental disorder, Interneurons, Gene Knockdown Techniques, Brain/pathology [MeSH], Zebrafish Proteins/genetics [MeSH], Gene Knockdown Techniques [MeSH], Zebrafish, Zebrafish Proteins/deficiency [MeSH], Animals [MeSH], Oxidoreductases Acting on CH-NH Group Donors/genetics [MeSH], Zebrafish [MeSH], Epilepsy/physiopathology [MeSH], Oxidoreductases Acting on CH-NH Group Donors/metabolism [MeSH], Brain/metabolism [MeSH], Interneurons/metabolism [MeSH], Epilepsy/pathology [MeSH], Phenotype [MeSH], Disease Models, Animal [MeSH], Epilepsy/genetics [MeSH], Zebrafish Proteins/metabolism [MeSH], Animals, Neurology. Diseases of the nervous system, RC346-429

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39334388
https://doaj.org/article/bf1fc1b2f36c455288d30524565c49a3
https://repository.publisso.de/resource/frl:6503649

Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina

Autoren: Nicholas Owen Maria Toms Yuan Tian et al.

Quelle: J Pathol
Owen, N, Toms, M, Tian, Y, Toualbi, L, Richardson, R, Young, R, Tracey-White, D, Dhami, P, Beck, S & Moosajee, M 2023, 'Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina', The Journal of pathology, vol. 259, no. 4, pp. 441-454. https://doi.org/10.1002/path.6056

Schlagwörter: Model organisms, 0301 basic medicine, retina, Cell Polarity/genetics, epigenome, Nerve Tissue Proteins/metabolism, Gene Expression, Nerve Tissue Proteins, Eye Proteins/genetics, Retina, Zebrafish/genetics, Epigenesis, Genetic, 03 medical and health sciences, Genetic, Zebrafish Proteins/genetics, Animals, Humans, Eye Proteins, Zebrafish, Retina/metabolism, Human Biology & Physiology, DNA methylation, iPSC, FOS: Clinical medicine, Stem Cells, Cell Cycle, Neurosciences, Cell Polarity, Membrane Proteins, Original Articles, Zebrafish Proteins, zebrafish, Polarity complex, Membrane Proteins/metabolism, RNA-seq, transcriptome, Genetics & Genomics, Epigenesis, Developmental Biology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/36656098
https://research.manchester.ac.uk/en/publications/60ced636-be6a-45dc-83d8-ef3bc68ced33
https://doi.org/10.1002/path.6056
https://discovery-pp.ucl.ac.uk/id/eprint/10163680/

wnt11f2 Zebrafish, an Animal Model for Development and New Insights in Bone Formation

Autoren: Caetano da Silva, Caroline Ostertag, Agnes Raman, Ratish et al.

Quelle: Zebrafish

Schlagwörter: 0301 basic medicine, Zebrafish Proteins/metabolism, wnt11f2, Review, Biochimie, biophysique & biologie moléculaire, high bone mass, 03 medical and health sciences, Osteogenesis, Zebrafish Proteins/genetics, Humans, Animals, Wnt pathways, development, Wnt Signaling Pathway, Zebrafish, 0303 health sciences, Cell Differentiation, Zebrafish Proteins, zebrafish, Life sciences, Models, Animal, Sciences du vivant, Animal Science and Zoology, Developmental Biology, Biochemistry, biophysics & molecular biology, Signal Transduction

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/36795617

The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish

Autoren: Veloso, Alexandra Bleuart, Anouk Conrard, Louise et al.

Weitere Verfasser: Veloso, Alexandra Bleuart, Anouk Conrard, Louise et al.

Quelle: BMC Biol
BMC Biology, Vol 22, Iss 1, Pp 1-23 (2024)
BMC Biology

Schlagwörter: Life Sciences & Biomedicine - Other Topics, 0301 basic medicine, Zebrafish Proteins/metabolism, Physiology, Plant Science, Structural Biology, Zebrafish Proteins -- genetics -- metabolism, Rho GTPases, Sorbs1, Biology (General), Lymphangiogenesis, Migration, Zebrafish, Cytoskeleton, 0303 health sciences, ALPHA-ACTININ, Lymphatic Vessels -- metabolism, Adaptor Proteins, Sciences bio-médicales et agricoles, Cytoskeleton -- metabolism, Life sciences, Signal Transducing -- metabolism, PROX1 EXPRESSION, Lymphangiogenesis -- physiology, Sciences du vivant, Adhesion, General Agricultural and Biological Sciences, Life Sciences & Biomedicine, Biotechnology, Research Article, BMP signaling, QH301-705.5, FOCAL ADHESION KINASE, Biochimie, biophysique & biologie moléculaire, EMBRYONIC LYMPHANGIOGENESIS, VINEXIN, General Biochemistry, Genetics and Molecular Biology, Zebrafish/genetics, 03 medical and health sciences, Zebrafish/metabolism, Zebrafish Proteins/genetics, Vegfc, Animals, GROWTH-FACTOR-C, Biology, INTERACTING PROTEIN, Ecology, Evolution, Behavior and Systematics, Lymphatic Vessels, Adaptor Proteins, Signal Transducing, Lymphatic Vessels/metabolism, Biochemistry, Genetics and Molecular Biology (all), Science & Technology, 31 Biological sciences, Zebrafish -- genetics -- metabolism, Cell Biology, STRESS FIBERS, 06 Biological Sciences, Zebrafish Proteins, Lymphangiogenesis/physiology, Adaptor Proteins, Signal Transducing/metabolism, Agricultural and Biological Sciences (all), Cytoskeleton/metabolism, Angiogenesis, CARDIAC LYMPHATICS, VASCULAR DEVELOPMENT, Biochemistry, biophysics & molecular biology, Developmental Biology

Dateibeschreibung: 1 full-text file(s): application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38414014
https://doaj.org/article/c363338c59c147acad9ab5d4c4848971
https://lirias.kuleuven.be/handle/20.500.12942/738865
https://doi.org/10.1186/s12915-024-01850-z

Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits

Autoren: Yiying Hu Alexander Hruscha Chenchen Pan et al.

Quelle: Mol Neurodegener
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-23 (2024)
Molecular neurodegeneration 19(1), 50 (2024). doi:10.1186/s13024-024-00735-7

Schlagwörter: metabolism [Zebrafish Proteins], pathology [Motor Neurons], TDP-43, Hypothalamus, Neuromuscular Junction, metabolism [Neuromuscular Junction], genetics [DNA-Binding Proteins], genetics [Zebrafish Proteins], Zebrafish Proteins/genetics [MeSH], Amyotrophic Lateral Sclerosis/pathology [MeSH], Neuromuscular Junction/pathology [MeSH], Animal model, Zebrafish, Motor Neurons/pathology [MeSH], Neuromuscular Junction/metabolism [MeSH], Amyotrophic Lateral Sclerosis/metabolism [MeSH], Animals [MeSH], DNA-Binding Proteins/genetics [MeSH], Metabolic dysfunction, DNA-Binding Proteins/metabolism [MeSH], Neurodegeneration, Animals, Genetically Modified [MeSH], Zebrafish [MeSH], ALS, Amyotrophic Lateral Sclerosis/genetics [MeSH], Motor Neurons/metabolism [MeSH], Disease Models, Animal [MeSH], Research Article, Zebrafish Proteins/metabolism [MeSH], pathology [Neuromuscular Junction], Animals, Genetically Modified, ddc:570, Tardbp protein, zebrafish, Animals, pathology [Amyotrophic Lateral Sclerosis], RC346-429, Motor Neurons, metabolism [Amyotrophic Lateral Sclerosis], Amyotrophic Lateral Sclerosis, RC952-954.6, metabolism [Motor Neurons], Zebrafish Proteins, DNA-Binding Proteins, genetics [Amyotrophic Lateral Sclerosis], Disease Models, Animal, Geriatrics, Neurology. Diseases of the nervous system, metabolism [DNA-Binding Proteins]

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38902734
https://doaj.org/article/3a903ab063944d74afd22278e76a4d88
https://hdl.handle.net/1887/4089826
https://repository.publisso.de/resource/frl:6499363
https://epub.ub.uni-muenchen.de/122904/

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements

Autoren: Baranasic, Damir Hörtenhuber, Matthias Balwierz, Piotr J et al.

Weitere Verfasser: Baranasic, Damir Hörtenhuber, Matthias Balwierz, Piotr J et al.

Quelle: Nat Genet
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
Baranasic, D, Hörtenhuber, M, Balwierz, P J, Zehnder, T, Mukarram, A K, Nepal, C, Várnai, C, Hadzhiev, Y, Jimenez-Gonzalez, A, Li, N, Wragg, J, D’Orazio, F M, Relic, D, Pachkov, M, Díaz, N, Hernández-Rodríguez, B, Chen, Z, Stoiber, M, Dong, M, Stevens, I, Ross, S E, Eagle, A, Martin, R, Obasaju, O, Rastegar, S, McGarvey, A C, Kopp, W, Chambers, E, Wang, D, Kim, H R, Acemel, R D, Naranjo, S, Łapiński, M, Chong, V, Mathavan, S, Peers, B, Sauka-Spengler, T, Vingron, M, Carninci, P, Ohler, U, Lacadie, S A, Burgess, S M, Winata, C, van Eeden, F, Vaquerizas, J M, Gómez-Skarmeta, J L, Onichtchouk, D, Brown, B J, Bogdanovic, O, van Nimwegen, E, Westerfield, M, Wardle, F C, Daub, C O, Lenhard, B & Müller, F 2022, ' Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements ', Nature Genetics, vol. 54, no. 7, pp. 1037-1050 . https://doi.org/10.1038/s41588-022-01089-w
Nature Genetics, 54, 1037–1050
Nature Genetics

Schlagwörter: Life sciences, biology, 0301 basic medicine, Cancer Research, atlas regulatornih elemenata, Organogenesis, Regulatory Sequences, Nucleic Acid, Biochimie, biophysique & biologie moléculaire, Article, Zebrafish/genetics, Mice, 03 medical and health sciences, Zebrafish Proteins/genetics, Databases, Genetic, Genetics, Animals, Humans, Zebrafish, Mammals, 0303 health sciences, Genome, Organogenesis/genetics, Chromatin/genetics, Gene Expression Regulation, Developmental, Molecular Sequence Annotation, Genomics, Regulatory Sequences, Nucleic Acid/genetics, Zebrafish Proteins, Chromatin, embrionalni razvoj, Sciences du vivant, Genome/genetics, Zebrafish/embryology, genomika, ddc:570, Technology Platforms, Genes, Cells and Cell-Based Medicine [Topic 1], zebrica, Biochemistry, biophysics & molecular biology

Dateibeschreibung: application/pdf; pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/35789323
http://hdl.handle.net/10261/279339
https://eprints.whiterose.ac.uk/189200/1/s41588-022-01089-w.pdf
https://edoc.mdc-berlin.de/id/eprint/21765/1/21765oa.pdf
https://edoc.unibas.ch/89500/
https://curis.ku.dk/ws/files/314439526/s41588_022_01089_w.pdf
https://publikationen.bibliothek.kit.edu/1000148259/148977449
https://publikationen.bibliothek.kit.edu/1000148259
https://doi.org/10.5445/IR/1000148259

Zebrafish as a model to investigate a biallelic gain-of-function variant in MSGN1, associated with a novel skeletal dysplasia syndrome

Autoren: Asuman Koparir Caroline Lekszas Kemal Keseroglu et al.

Weitere Verfasser: Asuman Koparir Caroline Lekszas Kemal Keseroglu et al.

Quelle: Hum Genomics
Human Genomics, Vol 18, Iss 1, Pp 1-13 (2024)

Schlagwörter: 0301 basic medicine, Messenger, Dwarfism, QH426-470, Iran, Osteochondrodysplasias, 03 medical and health sciences, Pregnancy, Genetics, Animals, Humans, Abnormalities, Multiple, RNA, Messenger, Zebrafish, 0303 health sciences, RNA, Messenger [MeSH], Female [MeSH], T-Box Domain Proteins/genetics [MeSH], Zebrafish Proteins/genetics [MeSH], Humans [MeSH], Gain of Function Mutation [MeSH], Iran [MeSH], Animals [MeSH], Dwarfism [MeSH], Abnormalities, Multiple [MeSH], Osteochondrodysplasias [MeSH], Research, Pregnancy [MeSH], Transcription Factors [MeSH], Zebrafish/genetics [MeSH], Zebrafish Proteins, 3. Good health, Gain of Function Mutation, RNA, Medicine, Female, Abnormalities, T-Box Domain Proteins, Multiple, Transcription Factors

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38448978
https://doaj.org/article/4ca8372a9ecd42798f65bafe5883ded4
https://resolver.sub.uni-goettingen.de/purl?gro-2/142700
https://repository.publisso.de/resource/frl:6508396
https://discovery-pp.ucl.ac.uk/id/eprint/10188889/

HB-EGF promotes progenitor cell proliferation and sensory neuron regeneration in the zebrafish olfactory epithelium.

Autoren: Sireci, Siran Kocagöz, Yigit Alkiraz, Aysu et al.

Quelle: The FEBS journal, 291 (10

Schlagwörter: Sciences bio-médicales et agricoles, Animals, Cell Proliferation -- drug effects, ErbB Receptors -- metabolism -- genetics, Heparin-binding EGF-like Growth Factor -- genetics -- metabolism, Intercellular Signaling Peptides and Proteins -- genetics -- metabolism -- pharmacology, Nerve Regeneration -- drug effects, Neurogenesis -- drug effects, Olfactory Mucosa -- metabolism -- cytology -- drug effects, Olfactory Receptor Neurons -- metabolism -- drug effects -- cytology, Signal Transduction, Stem Cells -- metabolism -- drug effects -- cytology, Zebrafish, Zebrafish Proteins -- genetics -- metabolism, neurogenesis, olfactory system, signaling, stem cells, tissue regeneration

Dateibeschreibung: 1 full-text file(s): application/pdf

Relation: uri/info:doi/10.1111/febs.17033; uri/info:pmid/38088047; https://dipot.ulb.ac.be/dspace/bitstream/2013/386868/3/HBEGF.pdf

Verfügbarkeit: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/386868
https://dipot.ulb.ac.be/dspace/bitstream/2013/386868/3/HBEGF.pdf

Cytochrome P450-dependent biotransformation capacities in embryonic, juvenile and adult stages of zebrafish (Danio rerio)—a state-of-the-art review

Autoren: Ann-Kathrin Loerracher Thomas Braunbeck

Quelle: Arch Toxicol

Schlagwörter: Mammals, 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Embryo, Nonmammalian, Cytochrome P-450 Enzyme System, 13. Climate action, Xenobiotic metabolism, Zebrafish Proteins/genetics [MeSH], Biotransformation, Biotransformation [MeSH], Zebrafish, Review Article, Embryo, Nonmammalian/metabolism [MeSH], Ecotoxicology, Mammals/metabolism [MeSH], Animals [MeSH], Cytochrome P-450 Enzyme System/metabolism [MeSH], Cytochrome P-450 Enzyme System/genetics [MeSH], Zebrafish [MeSH], Embryo, Toxicology, Cytochrome P450, Animals, Zebrafish Proteins

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s00204-021-03071-7.pdf
https://pubmed.ncbi.nlm.nih.gov/34148099
https://link.springer.com/article/10.1007/s00204-021-03071-7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241672/
https://link.springer.com/content/pdf/10.1007/s00204-021-03071-7.pdf
https://pubmed.ncbi.nlm.nih.gov/34148099/
https://europepmc.org/article/MED/34148099
https://repository.publisso.de/resource/frl:6451681

The adaptor protein Grb2b is an essential modulator for lympho-venous sprout formation in the zebrafish trunk

Autoren: Cristina Mauri Andreas van Impel Eirinn William Mackay et al.

Weitere Verfasser: Cristina Mauri Andreas van Impel Eirinn William Mackay et al.

Quelle: Angiogenesis

Schlagwörter: 0301 basic medicine, Cancer Research, Original Paper, 0303 health sciences, Physiology, 4. Education, Clinical Biochemistry, Endothelial Cells, Neovascularization, Physiologic, Development, Zebrafish Proteins, Vascular Endothelial Growth Factor Receptor-3, Veins, 03 medical and health sciences, Endothelial Cells/metabolism [MeSH], Mutation [MeSH], Zebrafish Proteins/genetics [MeSH], VEGFR3, Vasculature, Lymphangiogenesis, Zebrafish, GRB2 Adaptor Protein/metabolism [MeSH], Animals [MeSH], Vascular Endothelial Growth Factor Receptor-3/genetics [MeSH], Zebrafish/embryology [MeSH], GRB2 Adaptor Protein/genetics [MeSH], Neovascularization, Physiologic [MeSH], Veins/embryology [MeSH], Signal Transduction [MeSH], Lymphangiogenesis [MeSH], Angiogenesis, Lymphatic Vessels/embryology [MeSH], Vascular Endothelial Growth Factor Receptor-3/metabolism [MeSH], Zebrafish/genetics [MeSH], Zebrafish Proteins/metabolism [MeSH], Mutation, Animals, GRB2 Adaptor Protein, Lymphatic Vessels, Signal Transduction

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205915
https://pubmed.ncbi.nlm.nih.gov/33677657
https://pubmed.ncbi.nlm.nih.gov/33677657/
http://pubmed.ncbi.nlm.nih.gov/33677657/
https://link.springer.com/article/10.1007/s10456-021-09774-w
https://europepmc.org/article/MED/33677657
https://link.springer.com/content/pdf/10.1007/s10456-021-09774-w.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205915/
https://dspace.library.uu.nl/handle/1874/445793
https://repository.publisso.de/resource/frl:6446171

Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing

Autoren: Jingzhen Li Fei Liu Yuexia Lv et al.

Quelle: Nucleic Acids Res

Schlagwörter: 0301 basic medicine, DNA Repair, Cell Survival, Neurogenesis, Spindle Apparatus/ultrastructure, Retinal Neurons/cytology, Apoptosis, Spindle Apparatus, Genome Integrity, Repair and Replication, Retina, Gene Knockout Techniques, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Neural Stem Cells, Zebrafish Proteins/genetics, Genetics, Animals, Tumor Suppressor Protein p53/metabolism, Zebrafish, Neural Stem Cells/cytology, Exons, Zebrafish Proteins, Retina/embryology, Alternative Splicing, M Phase Cell Cycle Checkpoints, Zebrafish/embryology, Neurogenesis/genetics, CRISPR-Cas Systems, Tumor Suppressor Protein p53, DNA Damage, Retinal Neurons

Zugangs-URL: https://academic.oup.com/nar/article-pdf/49/4/2027/36398519/gkab003.pdf
https://pubmed.ncbi.nlm.nih.gov/33476374
https://researchonline.gcu.ac.uk/en/publications/59ab78ae-3af9-40ed-8f1d-94ac78497cf0
https://doi.org/10.1093/nar/gkab003
https://academic.oup.com/nar/article/49/4/2027/6105280
https://researchonline.gcu.ac.uk/en/publications/prpf31-is-essential-for-the-survival-and-differentiation-of-retin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913766
https://pubmed.ncbi.nlm.nih.gov/33476374/
https://europepmc.org/article/PMC/PMC7913766

The nuclear pore proteins Nup88/214 and T-cell acute lymphatic leukemia–associated NUP214 fusion proteins regulate Notch signaling

Autoren: Berit Jungnickel Daniel Kritsch Ralph H. Kehlenbach et al.

Weitere Verfasser: Berit Jungnickel Daniel Kritsch Ralph H. Kehlenbach et al.

Quelle: Journal of Biological Chemistry. 294:11741-11750

Schlagwörter: 0301 basic medicine, 0303 health sciences, Receptors, Notch, Recombinant Fusion Proteins, Active Transport, Cell Nucleus, Signal Transduction, Cell Line, Tumor [MeSH], Nuclear Pore Complex Proteins/metabolism [MeSH], Zebrafish Proteins/genetics [MeSH], Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism, RNA Interference, Receptors, Notch/metabolism, Morpholinos/metabolism [MeSH], RNA Interference [MeSH], Transcription Factor HES-1/antagonists, Morpholinos/metabolism, Morpholinos/genetics [MeSH], Nuclear Pore Complex Proteins/genetics [MeSH], Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism [MeSH], Receptors, Notch/metabolism [MeSH], Recombinant Fusion Proteins/genetics, Nuclear Pore Complex Proteins/genetics, Transcription Factor HES-1/metabolism, Zebrafish Proteins/metabolism, Zebrafish Proteins/metabolism [MeSH], Humans, Morpholinos/genetics, Nuclear Pore Complex Proteins/antagonists, Transcription Factor HES-1/metabolism [MeSH], Zebrafish Proteins/antagonists, Cell Line, Tumor, Humans [MeSH], RNA, Small Interfering/metabolism, Transcription Factor HES-1/genetics [MeSH], Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism [MeSH], Animals [MeSH], Nuclear Pore Complex Proteins/metabolism, Recombinant Fusion Proteins/metabolism, Zebrafish/metabolism [MeSH], Signal Transduction [MeSH], Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology, Recombinant Fusion Proteins/metabolism [MeSH], Animals, RNA, Small Interfering/metabolism [MeSH], Transcription Factor HES-1/genetics, Recombinant Fusion Proteins/genetics [MeSH], Zebrafish/metabolism, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology [MeSH], Zebrafish Proteins/genetics, Active Transport, Cell Nucleus [MeSH], Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism, Zebrafish Proteins, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Morpholinos, 3. Good health, Nuclear Pore Complex Proteins, 03 medical and health sciences, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Transcription Factor HES-1, RNA, Small Interfering, Zebrafish

Zugangs-URL: http://www.jbc.org/content/294/31/11741.full.pdf
https://pubmed.ncbi.nlm.nih.gov/31186352
https://www.sciencedirect.com/science/article/pii/S0021925820302179
https://pubmed.ncbi.nlm.nih.gov/31186352/
http://www.jbc.org/content/294/31/11741.short
https://europepmc.org/abstract/MED/31186352
https://www.jbc.org/article/S0021-9258(20)30217-9/fulltext
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682737
https://resolver.sub.uni-goettingen.de/purl?gro-2/74545
https://repository.publisso.de/resource/frl:6475700

Sexually dimorphic roles for the type 2 diabetes-associatedC2cd4bgene in murine glucose homeostasis

Autoren: Nikolay Ninov Zenobia B. Mehta Holger Kramer et al.

Weitere Verfasser: Nikolay Ninov Zenobia B. Mehta Holger Kramer et al.

Quelle: Diabetologia
Diabetologia, vol. 64, no. 4, pp. 850-864

Schlagwörter: Blood Glucose, Male, 0301 basic medicine, Genotype, Endocrinology and Diabetes, Biochimie, biophysique & biologie moléculaire, Glucose homeostasis, Weight Gain, Genome-wide association studies, Article, 1117 Public Health and Health Services, Endocrinology & Metabolism, 03 medical and health sciences, Animals, Biomarkers/blood, Blood Glucose/genetics, Blood Glucose/metabolism, Diabetes Mellitus, Type 2/genetics, Female, Follicle Stimulating Hormone/blood, Homeostasis/genetics, Humans, Insulin/blood, Insulin-Secreting Cells/metabolism, Mice, Inbred C57BL, Mice, Knockout, Nuclear Proteins/genetics, Phenotype, Pituitary Gland/metabolism, Sex Characteristics, Transcription Factors/genetics, Zebrafish/blood, Zebrafish/genetics, Zebrafish Proteins/blood, Zebrafish Proteins/genetics, C2CD4A/B, Follicle-stimulating hormone, Type 2 diabetes, Insulin-Secreting Cells, Homeostasis, Insulin, 0303 health sciences, Science & Technology, Nuclear Proteins, 1103 Clinical Sciences, Life sciences, 3. Good health, [SDV] Life Sciences [q-bio], Diabetes Mellitus, Type 2, Pituitary Gland, Endokrinologi och diabetes, Sciences du vivant, 1114 Paediatrics and Reproductive Medicine, Follicle Stimulating Hormone, Life Sciences & Biomedicine, Biomarkers, Biochemistry, biophysics & molecular biology, Transcription Factors

Dateibeschreibung: application/pdf

Zugangs-URL: https://orbi.uliege.be/bitstream/2268/256176/1/2021%20%20neda%20%20Sexually%20dimorphic%20roles%20for%20the%20type%202%20diabetes-associated%20C2cd4b%20gene%20in%20murine%20glucose%20homeostasis.pdf
https://link.springer.com/content/pdf/10.1007/s00125-020-05350-x.pdf
https://pubmed.ncbi.nlm.nih.gov/33492421
https://www.biorxiv.org/content/10.1101/2020.05.18.099200v1
https://www.biorxiv.org/content/10.1101/2020.05.18.099200v1.article-metrics
https://www.biorxiv.org/content/biorxiv/early/2020/05/19/2020.05.18.099200.full.pdf
https://www.scilit.net/article/70b1d1798fff5df530fc903dd36e772e
https://link.springer.com/article/10.1007/s00125-020-05350-x
https://link.springer.com/content/pdf/10.1007/s00125-020-05350-x.pdf
https://orbi.uliege.be/handle/2268/256176
https://www.ncbi.nlm.nih.gov/pubmed/33492421
https://europepmc.org/article/PMC/PMC7829492
http://hdl.handle.net/10044/1/92690
https://hdl.handle.net/2268/256176
https://doi.org/10.1007/s00125-020-05350-x
https://serval.unil.ch/notice/serval:BIB_0C8F018AB6C9
https://serval.unil.ch/resource/serval:BIB_0C8F018AB6C9.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_0C8F018AB6C91
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-450003

Analysis of U8 snoRNA Variants in Zebrafish Reveals How Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts

Autoren: Siobhan Crilly Denis L. J. Lafontaine Ludivine Wacheul et al.

Quelle: American journal of human genetics, 106 (5
Badrock, A P, Uggenti, C, Wacheul, L, Crilly, S, Jenkinson, E M, Rice, G I, Kasher, P R, Lafontaine, D L J, Crow, Y J & O'Keefe, R T 2020, ' Analysis of U8 snoRNA Variants in Zebrafish Reveals how Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts ', American Journal of Human Genetics, vol. 106, no. 5, pp. 694-706 . https://doi.org/10.1016/j.ajhg.2020.04.003
Badrock, A, Uggenti, C, Wacheul, L, Crilly, S, Jenkinson, E, Rice, G, Kasher, P, Lafontaine, D, Crow, Y & O'Keefe, R 2020, 'Analysis of U8 snoRNA Variants in Zebrafish Reveals how Bi-allelic Variants Cause Leukoencephalopathy with Calcifications and Cysts', American Journal of Human Genetics, vol. 106, no. 5, pp. 694-706. https://doi.org/10.1016/j.ajhg.2020.04.003

Schlagwörter: 0301 basic medicine, Génétique clinique, Embryonic Development, ribosomopathy, snoRNA, SNORD118, U8 snoRNA, 03 medical and health sciences, Leukoencephalopathies, Zebrafish Proteins/genetics, Embryonic Development/genetics, Small Nucleolar/genetics, Animals, Humans, RNA, Small Nucleolar, Central Nervous System Cysts/genetics, Central Nervous System Cysts, Alleles, Conserved Sequence, Zebrafish, 0303 health sciences, Leukoencephalopathies/genetics, Base Sequence, Animal, Cysts, Calcinosis/genetics, Cysts/genetics, Calcinosis, Zebrafish Proteins, zebrafish, 3. Good health, Disease Models, Animal, Disease Models, Mutation, RNA, Tumor Suppressor Protein p53/genetics, Zebrafish/embryology, Labrune syndrome, Tumor Suppressor Protein p53, Biologie, RNA, Small Nucleolar/genetics, leukoencephalopathy with calcifications and cysts

Dateibeschreibung: 1 full-text file(s): application/pdf; application/octet-stream; application/pdf

Zugangs-URL: http://www.cell.com/article/S0002929720301129/pdf
https://pubmed.ncbi.nlm.nih.gov/32359472
https://research.manchester.ac.uk/en/publications/cf6ab27e-3ac6-4fc6-bd3b-aea378e05417
https://doi.org/10.1016/j.ajhg.2020.04.003
https://www.sciencedirect.com/science/article/pii/S0002929720301129
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212298
https://www.research.manchester.ac.uk/portal/en/publications/analysis-of-u8-snorna-variants-in-zebrafish-reveals-how-biallelic-variants-cause-leukoencephalopathy-with-calcifications-and-cysts(cf6ab27e-3ac6-4fc6-bd3b-aea378e05417).html
https://pubmed.ncbi.nlm.nih.gov/32359472/
https://www.ncbi.nlm.nih.gov/pubmed/32359472
https://www.cell.com/ajhg/fulltext/S0002-9297(20)30112-9
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/307345
https://hdl.handle.net/20.500.11820/97a46b3b-bad9-48c1-98d3-eee1326b8a59
https://www.pure.ed.ac.uk/ws/files/142014222/BW1OWN_O
https://pure.manchester.ac.uk/ws/files/162365839/Badrock_et_al_AJHG_revision_final_changes_accepted_for_PURE.pdf
https://research.manchester.ac.uk/en/publications/cf6ab27e-3ac6-4fc6-bd3b-aea378e05417
https://doi.org/10.1016/j.ajhg.2020.04.003

The glucocorticoid receptor is affected by its target ZBTB16 in a dissociated manner

Autoren: Galuh, S. Faught, E. Klaassen, I. et al.

Schlagwörter: Receptors, Glucocorticoid/metabolism, Glucocorticoid/genetics, Zebrafish, Animals, Humans, Hydrocortisone/pharmacology, Dexamethasone/pharmacology, Glucocorticoids/pharmacology, Promyelocytic Leukemia Zinc Finger Protein/genetics, Promyelocytic Leukemia Zinc Finger Protein/metabolism, Zebrafish Proteins/genetics, Zebrafish Proteins/metabolism, Osteoarthritis/metabolism, PLZF, cortisol, intracellular feedback, transactivation, transrepression

Relation: The Journal of endocrinology; https://iris.unil.ch/handle/iris/269566; serval:BIB_60434A92838A; 001561630900003

Verfügbarkeit: https://iris.unil.ch/handle/iris/269566
https://doi.org/10.1530/JOE-24-0283