Výsledky vyhľadávania - "Yeger-Lotem E"

Deciphering the impact of genomic variation on function.

Autori: Engreitz, Jesse M. Lawson, Heather A. Singh, Harinder a ďalší

Zdroj: Nature; Sep2024, Vol. 633 Issue 8028, p47-57, 11p

ProteinWeaver: A webtool to visualize ontology-annotated protein networks.

Autori: Anderson, Oliver Barelvi, Altaf O'Brien, Aden a ďalší

Zdroj: PLoS ONE; 9/5/2025, Vol. 20 Issue 9, p1-17, 17p

Predmety: GENE ontology, BIOLOGICAL networks, DATA visualization software, GENE regulatory networks, BIOLOGICAL systems, MOLECULAR interactions, EMPIRICAL research, HYPOTHESIS

Cytokine expression profile in the human brain of older adults.

Autori: Godoy, Juliana Beker Vialle, Ricardo A. dos Santos, Loren a ďalší

Zdroj: Journal of Neuroinflammation; 10/3/2025, Vol. 22 Issue 1, p1-16, 16p

Predmety: ALZHEIMER'S disease, NEUROINFLAMMATION, MICROGLIA, CYTOKINES, RNA sequencing, BIOMARKERS, COGNITION disorders, ASTROCYTES

Genetic variations and recurrence in stage III Korean colorectal cancer: Insights from tumor-only mutation analysis.

Autori: Jeon, Hajin Lee, Jong Lyul Shim, Hyeran a ďalší

Zdroj: PLoS ONE; 5/23/2025, Vol. 20 Issue 5, p1-21, 21p

Predmety: STATISTICAL significance, GENETIC variation, SINGLE nucleotide polymorphisms, KOREANS, DATABASES

Robust consensus nuclear and cell segmentation.

Autori: Irfan, Melis O. González-Solares, Eduardo A. Whitmarsh, Tristan a ďalší

Zdroj: Frontiers in Genetics; 2025, p1-16, 16p

Predmety: CELL segmentation, IMAGE segmentation, COMPUTER-assisted image analysis (Medicine), IMAGE analysis, SOFTWARE development tools

Visible neural networks for multi-omics integration: a critical review.

Autori: Selby, David Antony Jakhmola, Rashika Sprang, Maximilian a ďalší

Zdroj: Frontiers in Artificial Intelligence; 2025, p1-17, 17p

VARista: a free web platform for streamlined whole-genome variant analysis across T2T, hg38, and hg19.

Autori: Hadar, Noam Dolgin, Vadim Oustinov, Katya a ďalší

Zdroj: Human Genetics; May2024, Vol. 143 Issue 5, p695-701, 7p

Predmety: GENETIC disorders, CRITICAL thinking, GENE expression, RESEARCH personnel, SCIENTIFIC community, FETUS

Integration of Bulk and Single-Cell Transcriptomics Reveals BCL2L14 as a Novel IGKC+ T Cell-Associated Therapeutic Target in Breast Cancer.

Autori: He, Jiaming Akhtar, Aiman Li, Jing a ďalší

Zdroj: Journal of Inflammation Research; Jun2025, Vol. 18, p7215-7234, 20p

Predmety: MOLECULAR biology, MACHINE learning, GENE expression, MENDELIAN randomization, REGULATOR genes

Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis.

Autori: Garcia-Toscano, Laura Currey, Heather N. Hincks, Joshua C. a ďalší

Zdroj: PLoS Genetics; 12/26/2024, Vol. 20 Issue 12, p1-24, 24p

Predmety: MOTOR neuron diseases, HEAT shock proteins, TDP-43 proteinopathies, SMALL molecules, CAENORHABDITIS elegans, AMYOTROPHIC lateral sclerosis

Compression-based inference of network motif sets.

Autori: Bénichou, Alexis Masson, Jean-Baptiste Vestergaard, Christian L.

Zdroj: PLoS Computational Biology; 10/10/2024, Vol. 20 Issue 10, p1-29, 29p

Predmety: BIOLOGICAL neural networks, BIOLOGICAL networks, DROSOPHILA melanogaster, ELECTRIC circuit networks, LOGIC circuits, CIONA intestinalis

Tissue-adjusted pathway analysis of cancer (TPAC): A novel approach for quantifying tumor-specific gene set dysregulation relative to normal tissue.

Autori: Frost, H. Robert

Zdroj: PLoS Computational Biology; 1/11/2024, Vol. 20 Issue 1, p1-22, 22p

Predmety: GENE expression, TUMOR suppressor genes, GENES, TRANSCRIPTOMES, HUMAN genes, TEST methods

A reference map of the human binary protein interactome.

Autori: Luck, Katja Kim, Dae-Kyum Lambourne, Luke a ďalší

Zdroj: Nature; 4/16/2020, Vol. 580 Issue 7803, p402-408, 7p, 1 Diagram, 14 Graphs

Network motif detection using hidden markov models.

Autori: Bampos, Costas Megalooikonomou, Vasileios

Zdroj: Scientific Reports; 11/25/2025, Vol. 15 Issue 1, p1-15, 15p

Predmety: HIDDEN Markov models, SUBGRAPHS, COMMUNICATION network analysis, GRAPH theory, STATISTICAL models, COMPUTATIONAL complexity, REPRESENTATIONS of graphs, MODEL validation

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling.

Autori: Lau, Hayley R. Smith, Hayley S. Alural, Begüm a ďalší

Zdroj: Molecular Oncology; Oct2025, Vol. 19 Issue 10, p2833-2859, 27p

Age‐related loss of intestinal barrier integrity plays an integral role in thymic involution and T cell ageing.

Autori: Conway, Jessica De Jong, Erica N. White, Andrea J. a ďalší

Zdroj: Aging Cell; Mar2025, Vol. 24 Issue 3, p1-19, 19p

Predmety: REGULATORY T cells, T-cell exhaustion, INTESTINAL barrier function, MEMBRANE permeability (Technology), CELLULAR aging, IMMUNOSENESCENCE, T cells

sc2GWAS: a comprehensive platform linking single cell and GWAS traits of human.

Autori: Yin, Mingxue Feng, Chenchen Yu, Zhengmin a ďalší

Zdroj: Nucleic Acids Research; 1/6/2025, Vol. 53 Issue D1, pD1151-D1161, 11p

Genetic Contribution to Medium-Term Disease Activity in Multiple Sclerosis.

Autori: Mascia, Elisabetta Nale, Valentina Ferrè, Laura a ďalší

Zdroj: Molecular Neurobiology; Jan2025, Vol. 62 Issue 1, p322-334, 13p

A robust model for cell type-specific interindividual variation in single-cell RNA sequencing data.

Autori: Chen, Minhui Dahl, Andy

Zdroj: Nature Communications; 6/19/2024, Vol. 15 Issue 1, p1-12, 12p

Predmety: RNA sequencing, INDUCED pluripotent stem cells, GENE expression profiling, CYTOLOGY

Escherichia coli adaptation under prolonged resource exhaustion is characterized by extreme parallelism and frequent historical contingency.

Autori: Zion, Shira Katz, Sophia Hershberg, Ruth

Zdroj: PLoS Genetics; 6/17/2024, Vol. 20 Issue 6, p1-22, 22p

Predmety: WHOLE genome sequencing, BACTERIAL adaptation

Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.

Autori: Rodina, Anna Xu, Chao Digwal, Chander S. a ďalší

Zdroj: Nature Communications; 9/26/2023, Vol. 14 Issue 1, p1-26, 26p

Predmety: PROTEIN-protein interactions, CANCER cells, HEAT shock proteins, PROOF of concept, TARGETED drug delivery