Suchergebnisse - "Weightlessness"

Brain power comparison between microgravity and head-down tilt bed rest: an electroencephalography approach.

Autoren: Sevilla-García M Quivira-Lopesino A Cuesta P et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 27; Vol. 15 (1), pp. 42314. Date of Electronic Publication: 2025 Nov 27.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Electroencephalography*/methods , Head-Down Tilt*/physiology , Bed Rest* , Weightlessness* , Brain*/physiology, Humans ; Male ; Adult ; Female ; Space Flight ; Weightlessness Simulation

Effect of simulated microgravity via head-down tilt on intracranial compliance, brain oscillations and cardiovascular autonomic modulation.

Autoren: Mendes Zambetta R De Favari Signini É Catai AM et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 27; Vol. 15 (1), pp. 42316. Date of Electronic Publication: 2025 Nov 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Head-Down Tilt*/physiology , Weightlessness Simulation* , Autonomic Nervous System*/physiology , Brain*/physiology, Humans ; Female ; Male ; Adult ; Cerebrovascular Circulation/physiology ; Weightlessness ; Young Adult ; Space Flight

Microgravity Impacts the Expression of Aging-Associated Candidate Gene Targets in the p53 Regulatory Network.

Autoren: Kuznetsov NV Vlasova DD Kotikova AA et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 18; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/metabolism , Gene Regulatory Networks* , Aging*/genetics , Weightlessness* , Gene Expression Regulation*, Humans ; Male ; Adult ; Transcriptome ; T-Lymphocytes/metabolism ; Signal Transduction ; Cellular Senescence/genetics ; Gene Expression Profiling ; Weightlessness Simulation

Integrating 3D Osteocyte Culture, Microgravity Simulation, and Fluid Flow Reveals Mechanisms of Osteocyte Mechanosensation and Calcium Signaling Altered by Disuse.

Autoren: Yu K Tuladhar A Dankberg S et al.

Quelle: Biomolecules [Biomolecules] 2025 Oct 31; Vol. 15 (11). Date of Electronic Publication: 2025 Oct 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

MeSH-Schlagworte: Osteocytes*/metabolism , Osteocytes*/cytology , Calcium Signaling* , Weightlessness Simulation* , Mechanotransduction, Cellular* , Cell Culture Techniques, Three Dimensional*/methods, Animals ; Mice ; Weightlessness ; RANK Ligand/metabolism ; RANK Ligand/genetics ; Stress, Mechanical ; Cell Line ; Adaptor Proteins, Signal Transducing

Muscle-specific atrophy of the lower limb musculature in response to simulated microgravity exposure in women.

Autoren: Rogers KR Yoon G Vincenty CS et al.

Quelle: Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2025 Sep 01; Vol. 139 (3), pp. 759-765. Date of Electronic Publication: 2025 Aug 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 8502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1601 (Electronic) Linking ISSN: 01617567 NLM ISO Abbreviation: J Appl Physiol (1985) Subsets: MEDLINE

MeSH-Schlagworte: Muscular Atrophy*/physiopathology , Muscular Atrophy*/pathology , Weightlessness Simulation*/adverse effects , Weightlessness Simulation*/methods , Muscle, Skeletal*/physiopathology , Muscle, Skeletal*/pathology , Lower Extremity*/physiopathology, Humans ; Female ; Adult ; Weightlessness/adverse effects ; Magnetic Resonance Imaging/methods ; Head-Down Tilt/physiology ; Space Flight

Cell cycle and HIF-1 related gene expression alteration in thyroid cell lines under microgravity.

Autoren: Ahn JH Yi JW

Quelle: Oncology research [Oncol Res] 2025 Jul 18; Vol. 33 (8), pp. 1909-1931. Date of Electronic Publication: 2025 Jul 18 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Tech Science Press Country of Publication: United States NLM ID: 9208097 Publication Model: eCollection Cited Medium: Internet ISSN: 1555-3906 (Electronic) Linking ISSN: 09650407 NLM ISO Abbreviation: Oncol Res Subsets: MEDLINE

MeSH-Schlagworte: Thyroid Neoplasms*/genetics , Thyroid Neoplasms*/pathology , Thyroid Neoplasms*/metabolism , Weightlessness* , Gene Expression Regulation, Neoplastic* , Cell Cycle*/genetics , Hypoxia-Inducible Factor 1, alpha Subunit*/genetics , Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism , Thyroid Gland*/metabolism , Thyroid Gland*/pathology, Humans ; Weightlessness Simulation ; Cell Line, Tumor ; Cell Movement/genetics ; Gene Expression Profiling

The Effects of Microgravity on the Structure and Function of Cardiomyocytes.

Autoren: González-Torres LF Grimm D Krüger M

Quelle: Biomolecules [Biomolecules] 2025 Aug 30; Vol. 15 (9). Date of Electronic Publication: 2025 Aug 30.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

MeSH-Schlagworte: Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/cytology , Myocytes, Cardiac*/physiology , Weightlessness*, Humans ; Animals ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/metabolism ; Space Flight ; Weightlessness Simulation

Parabolic flight as a research platform to investigate ophthalmic changes in microgravity.

Autoren: Nguyen T Ong J Aman S et al.

Quelle: Life sciences in space research [Life Sci Space Res (Amst)] 2025 Aug; Vol. 46, pp. 100-105. Date of Electronic Publication: 2025 Mar 05.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Ltd Country of Publication: Netherlands NLM ID: 101632373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2214-5532 (Electronic) Linking ISSN: 22145524 NLM ISO Abbreviation: Life Sci Space Res (Amst) Subsets: MEDLINE

MeSH-Schlagworte: Weightlessness*/adverse effects , Space Flight* , Eye*, Humans ; Intraocular Pressure ; Eye Movements/physiology ; Weightlessness Simulation ; Intracranial Pressure ; Reflex, Vestibulo-Ocular ; Hypergravity

Protein bioactive complexes promote osteogenesis under microgravity environment.

Autoren: Kabir A Mukilarasi B Manohar A et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Apr; Vol. 303, pp. 140483. Date of Electronic Publication: 2025 Feb 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Osteogenesis*/drug effects , Weightlessness*, Animals ; Zebrafish ; Mice ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Osteoblasts/cytology ; Reactive Oxygen Species/metabolism ; Weightlessness Simulation ; Cell Line ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Humans ; Bone Regeneration/drug effects

Alterations in the intersegmental coordination of landing from a jump in a microgravity environment.

Autoren: Toussaint TD Pypaert JM Gambelli CN et al.

Quelle: Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2025 Mar 01; Vol. 138 (3), pp. 848-856. Date of Electronic Publication: 2025 Feb 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 8502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1601 (Electronic) Linking ISSN: 01617567 NLM ISO Abbreviation: J Appl Physiol (1985) Subsets: MEDLINE

MeSH-Schlagworte: Weightlessness*, Humans ; Male ; Adult ; Movement/physiology ; Young Adult ; Biomechanical Phenomena/physiology ; Weightlessness Simulation/methods ; Female ; Gravitation ; Foot/physiology

Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress.

Autoren: Wang Y Chen T Shi Z et al.

Quelle: Drug design, development and therapy [Drug Des Devel Ther] 2025 Feb 24; Vol. 19, pp. 1289-1303. Date of Electronic Publication: 2025 Feb 24 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome*/drug effects , Weightlessness*/adverse effects , Ginsenosides*/pharmacology , Ginsenosides*/chemistry , Ginsenosides*/isolation & purification , Intestines*/drug effects , Intestines*/microbiology, Animals ; Rats ; Rats, Sprague-Dawley ; Male ; Panax/chemistry ; Hindlimb Suspension ; Weightlessness Simulation

Molecular Mechanism of Microgravity-Induced Intestinal Flora Dysbiosis on the Abnormalities of Liver and Brain Metabolism.

Autoren: Xiong Y Guo J Yu W et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Mar 27; Vol. 26 (7). Date of Electronic Publication: 2025 Mar 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome*/physiology , Liver*/metabolism , Liver*/pathology , Brain*/metabolism , Dysbiosis*/metabolism , Dysbiosis*/microbiology , Dysbiosis*/etiology , Weightlessness*/adverse effects, Animals ; Mice ; Male ; Space Flight ; Weightlessness Simulation/adverse effects ; Mice, Inbred C57BL ; Metabolomics/methods

SIRT5 Alleviates Apoptosis of Vascular Endothelial Cells Under Simulated Microgravity via Desuccinylation of ERO1A.

Autoren: Pan Y Zhang Q Li C et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Mar 23; Vol. 26 (7). Date of Electronic Publication: 2025 Mar 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Apoptosis* , Sirtuins*/metabolism , Sirtuins*/genetics , Weightlessness Simulation*, Humans ; Human Umbilical Vein Endothelial Cells/metabolism ; Protein Processing, Post-Translational ; Lysine/metabolism ; Weightlessness ; Proteome

Two-photon polymerization of miniaturized 3D scaffolds optimized for studies on glioblastoma multiforme in spaceflight-like microgravity conditions.

Autoren: Genchi GG Conci C Şen Ö et al.

Quelle: Biofabrication [Biofabrication] 2025 Mar 12; Vol. 17 (2). Date of Electronic Publication: 2025 Mar 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: IOP Pub Country of Publication: England NLM ID: 101521964 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-5090 (Electronic) Linking ISSN: 17585082 NLM ISO Abbreviation: Biofabrication Subsets: MEDLINE

MeSH-Schlagworte: Glioblastoma*/pathology , Glioblastoma*/metabolism , Tissue Scaffolds*/chemistry , Space Flight* , Weightlessness* , Photons*, Humans ; Cell Line, Tumor ; Polymerization ; Miniaturization ; Brain Neoplasms/pathology ; Weightlessness Simulation

Effects of simulated microgravity on dental pulp stem cell stemness.

Autoren: Hou H Qiu Z Che J et al.

Quelle: Journal of molecular histology [J Mol Histol] 2025 Feb 26; Vol. 56 (2), pp. 97. Date of Electronic Publication: 2025 Feb 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Netherlands Country of Publication: Netherlands NLM ID: 101193653 Publication Model: Electronic Cited Medium: Internet ISSN: 1567-2387 (Electronic) Linking ISSN: 15672379 NLM ISO Abbreviation: J Mol Histol Subsets: MEDLINE

MeSH-Schlagworte: Dental Pulp*/cytology , Weightlessness Simulation* , Stem Cells*/cytology , Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Mesenchymal Stem Cells*/metabolism, Humans ; Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Osteogenesis ; MAP Kinase Signaling System ; Weightlessness

Integrated spaceflight transcriptomic analyses and simulated space experiments reveal key molecular features and functional changes driven by space stressors in space-flown C. elegans.

Autoren: Zhang G Zhao L Li Z et al.

Quelle: Life sciences in space research [Life Sci Space Res (Amst)] 2025 Feb; Vol. 44, pp. 10-22. Date of Electronic Publication: 2024 Nov 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Ltd Country of Publication: Netherlands NLM ID: 101632373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2214-5532 (Electronic) Linking ISSN: 22145524 NLM ISO Abbreviation: Life Sci Space Res (Amst) Subsets: MEDLINE

MeSH-Schlagworte: Caenorhabditis elegans*/genetics , Caenorhabditis elegans*/radiation effects , Caenorhabditis elegans*/physiology , Space Flight* , Transcriptome* , Weightlessness Simulation*, Animals ; Gene Expression Profiling ; Weightlessness ; Longevity/genetics ; Caenorhabditis elegans Proteins/genetics

Simulated microgravity environment inhibits matrix mineralization during the osteoblast to osteocyte differentiation.

Autoren: Nakagaki R Mukaibo T Monir A et al.

Quelle: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Dec 20; Vol. 739, pp. 150963. Date of Electronic Publication: 2024 Nov 08.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH-Schlagworte: Osteoblasts*/metabolism , Osteoblasts*/cytology , Osteocytes*/metabolism , Osteocytes*/cytology , Cell Differentiation* , Weightlessness Simulation*, Animals ; Calcification, Physiologic ; Cell Line ; Fibroblast Growth Factor-23/metabolism ; Mice ; Weightlessness

Mechanisms and Countermeasures for Muscle Atrophy in Microgravity.

Autoren: Liu Y Cao X Zhou Q et al.

Quelle: Cells [Cells] 2024 Dec 20; Vol. 13 (24). Date of Electronic Publication: 2024 Dec 20.

Publikationsart: Journal Article; Review; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH-Schlagworte: Muscular Atrophy*/pathology , Muscular Atrophy*/metabolism , Weightlessness*/adverse effects, Humans ; Animals ; Muscle, Skeletal/pathology ; Muscle, Skeletal/metabolism ; Weightlessness Countermeasures ; Space Flight ; Myostatin/metabolism

Feasibility of ultrasound-guided nerve blocks in simulated microgravity: a proof-of-concept study for regional anaesthesia during deep space missions.

Autoren: Kiberd MB Brownbridge R Mackin M et al.

Quelle: British journal of anaesthesia [Br J Anaesth] 2024 Dec; Vol. 133 (6), pp. 1276-1283. Date of Electronic Publication: 2024 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 0372541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-6771 (Electronic) Linking ISSN: 00070912 NLM ISO Abbreviation: Br J Anaesth Subsets: MEDLINE

MeSH-Schlagworte: Nerve Block*/methods , Space Flight* , Feasibility Studies* , Weightlessness Simulation* , Ultrasonography, Interventional*/methods , Proof of Concept Study*, Animals ; Cattle ; Anesthesia, Conduction/methods ; Humans ; Weightlessness

Exploring the effects of simulated microgravity on esophageal cancer cells: insights into morphological, growth behavior, adhesion, and genetic damage.

Autoren: Altaie S Alrawi A Duan X et al.

Quelle: Journal of biological physics [J Biol Phys] 2024 Dec; Vol. 50 (3-4), pp. 351-366. Date of Electronic Publication: 2024 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Kluwer Country of Publication: Netherlands NLM ID: 0417731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0689 (Electronic) Linking ISSN: 00920606 NLM ISO Abbreviation: J Biol Phys Subsets: MEDLINE

MeSH-Schlagworte: Esophageal Neoplasms*/pathology , DNA Damage* , Weightlessness Simulation* , Cell Adhesion* , Cell Proliferation*, Humans ; Cell Line, Tumor ; Cell Survival ; Weightlessness