Suchergebnisse - "WEIGHT loss"

Gradually, then Suddenly: Nutrition in an Era of Medically Induced Weight Loss.

Autoren: Bergia RE Davis EM Campbell WW

Quelle: The Journal of nutrition [J Nutr] 2025 Dec; Vol. 155 (12), pp. 4109-4112. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0404243 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-6100 (Electronic) Linking ISSN: 00223166 NLM ISO Abbreviation: J Nutr Subsets: MEDLINE

MeSH-Schlagworte: Weight Loss* , Obesity*/therapy, Humans ; Exercise

Letter to Editor Regarding "Weight Loss Maintenance 1 year after the Swallowable Gastric Balloon: Results from an International Multicenter Study".

Autoren: Ul Abedeen Z Saleem A Bibi K

Quelle: Obesity surgery [Obes Surg] 2025 Nov; Vol. 35 (11), pp. 4864-4865. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Letter

Info zur Zeitschrift: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9106714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1708-0428 (Electronic) Linking ISSN: 09608923 NLM ISO Abbreviation: Obes Surg Subsets: MEDLINE

MeSH-Schlagworte: Gastric Balloon* , Weight Loss* , Obesity, Morbid*/therapy , Obesity, Morbid*/surgery, Humans ; Multicenter Studies as Topic ; Treatment Outcome ; Retrospective Studies

Neurobeachin (NBEA) is a novel gene associated with GLP-1 receptor agonist associated weight loss.

Autoren: Mariam-Smith A Breeyear JH Daniels NJ et al.

Quelle: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Oct; Vol. 27 (10), pp. 5632-5642. Date of Electronic Publication: 2025 Jul 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

MeSH-Schlagworte: Weight Loss*/genetics , Weight Loss*/drug effects , Glucagon-Like Peptide-1 Receptor Agonists* , Obesity*/drug therapy , Obesity*/genetics , Nerve Tissue Proteins*/genetics , Adaptor Proteins, Signal Transducing*/genetics, Humans ; Male ; Female ; Middle Aged ; Aged ; Adult ; United Kingdom ; Cohort Studies ; Liraglutide/therapeutic use

HbA1c reduction with tirzepatide in people with type 2 diabetes: The contribution of weight loss assessed by a mediation analysis.

Autoren: Vilsbøll T Malecki MT Sharma P et al.

Quelle: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Oct; Vol. 27 (10), pp. 5498-5505. Date of Electronic Publication: 2025 Jul 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

MeSH-Schlagworte: Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/complications , Glycated Hemoglobin*/analysis , Glycated Hemoglobin*/metabolism , Glycated Hemoglobin*/drug effects , Hypoglycemic Agents*/therapeutic use , Tirzepatide*/therapeutic use , Weight Loss*/drug effects, Aged ; Female ; Humans ; Male ; Middle Aged ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Gastric Inhibitory Polypeptide ; Glucagon-Like Peptide-1 Receptor Agonists ; Glucagon-Like Peptides/therapeutic use ; Treatment Outcome ; Randomized Controlled Trials as Topic ; Clinical Trials, Phase III as Topic ; Glucagon-Like Peptide 1

Using obesity management medications within the first year after laparoscopic sleeve gastrectomy may enhance weight-loss outcomes.

Autoren: Chen CY Chi PJ Tu WL et al.

Quelle: Obesity surgery [Obes Surg] 2025 Oct; Vol. 35 (10), pp. 4370-4382. Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9106714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1708-0428 (Electronic) Linking ISSN: 09608923 NLM ISO Abbreviation: Obes Surg Subsets: MEDLINE

MeSH-Schlagworte: Weight Loss*/drug effects , Laparoscopy* , Gastrectomy*/methods , Obesity, Morbid*/surgery , Obesity, Morbid*/drug therapy , Anti-Obesity Agents*/therapeutic use, Humans ; Female ; Male ; Retrospective Studies ; Adult ; Middle Aged ; Treatment Outcome ; Body Mass Index

Personalizing a Weight Loss Program Using Cognitive-Behavioral Phenotypes to Improve Engagement and Weight Loss in Adults With Overweight or Obesity: Quasi-Experimental Study.

Autoren: Szypula J Jarvstad A Jones LA et al.

Quelle: JMIR formative research [JMIR Form Res] 2025 Dec 01; Vol. 9, pp. e72645. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101726394 Publication Model: Electronic Cited Medium: Internet ISSN: 2561-326X (Electronic) Linking ISSN: 2561326X NLM ISO Abbreviation: JMIR Form Res Subsets: MEDLINE

MeSH-Schlagworte: Weight Reduction Programs*/methods , Obesity*/therapy , Obesity*/psychology , Weight Loss* , Overweight*/therapy , Overweight*/psychology , Cognitive Behavioral Therapy*/methods, Humans ; Female ; Male ; Adult ; Middle Aged ; United Kingdom ; Phenotype ; Aged ; Adolescent ; Young Adult ; Aged, 80 and over ; Surveys and Questionnaires

Precision nutrition for obesity management: A gut microbiota-centered weight-loss approach.

Autoren: Carvalho LM da Mota JCNL Ribeiro AA et al.

Quelle: Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition] 2025 Dec; Vol. 140, pp. 112892. Date of Electronic Publication: 2025 Jul 04.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8802712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1244 (Electronic) Linking ISSN: 08999007 NLM ISO Abbreviation: Nutrition Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome*/physiology , Obesity*/microbiology , Obesity*/diet therapy , Precision Medicine*/methods , Weight Loss* , Obesity Management*/methods, Humans ; Diet ; Diet, Mediterranean

Weight Loss-Associated Remodeling of Adipose Tissue Immunometabolism.

Autoren: Basso PJ Schcolnik-Cabrera A Zhu M et al.

Quelle: Obesity reviews : an official journal of the International Association for the Study of Obesity [Obes Rev] 2025 Dec; Vol. 26 (12), pp. e13975. Date of Electronic Publication: 2025 Jun 30.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Blackwell Publishing Country of Publication: England NLM ID: 100897395 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-789X (Electronic) Linking ISSN: 14677881 NLM ISO Abbreviation: Obes Rev Subsets: MEDLINE

MeSH-Schlagworte: Weight Loss*/immunology , Weight Loss*/physiology , Adipose Tissue*/metabolism , Adipose Tissue*/immunology , Obesity*/immunology , Obesity*/metabolism , Obesity*/therapy, Humans ; Inflammation/immunology ; Inflammation/metabolism

Impact of weight change on the prognosis of cancer patients: A multicenter, prospective study.

Autoren: Zhang G Zhang C Fida S et al.

Quelle: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2025 Dec; Vol. 70, pp. 69-76. Date of Electronic Publication: 2025 Sep 13.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101654592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4577 (Electronic) Linking ISSN: 24054577 NLM ISO Abbreviation: Clin Nutr ESPEN Subsets: MEDLINE

MeSH-Schlagworte: Neoplasms*/mortality , Weight Loss* , Weight Gain*, Humans ; Male ; Female ; Prospective Studies ; Middle Aged ; Prognosis ; Aged ; Adult ; China/epidemiology ; Risk Factors ; Proportional Hazards Models ; Body Mass Index

Efficacy and safety of survodutide on glycemic control and weight loss in adults: A systematic review and meta-analysis.

Autoren: Xiao YJ Yu S Zhang YL et al.

Quelle: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Dec; Vol. 27 (12), pp. 7062-7074. Date of Electronic Publication: 2025 Sep 08.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

MeSH-Schlagworte: Weight Loss*/drug effects , Glycemic Control*/methods , Hypoglycemic Agents*/therapeutic use , Hypoglycemic Agents*/adverse effects , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/blood, Humans ; Adult ; Glycated Hemoglobin/analysis ; Randomized Controlled Trials as Topic ; Blood Glucose/drug effects ; Waist Circumference/drug effects ; Treatment Outcome

Thigh-muscle volume change in response to diet, exercise, and weight-loss in overweight and obese individuals-8-year follow-up data from the Osteoarthritis Initiative.

Autoren: Ziegeler K Kreutzinger V Akkaya Z et al.

Quelle: Skeletal radiology [Skeletal Radiol] 2025 Dec; Vol. 54 (12), pp. 2651-2658. Date of Electronic Publication: 2025 May 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7701953 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2161 (Electronic) Linking ISSN: 03642348 NLM ISO Abbreviation: Skeletal Radiol Subsets: MEDLINE

MeSH-Schlagworte: Weight Loss*/physiology , Magnetic Resonance Imaging*/methods , Obesity*/therapy , Obesity*/complications , Osteoarthritis, Knee*/diagnostic imaging , Overweight*/therapy , Muscle, Skeletal*/diagnostic imaging , Muscle, Skeletal*/pathology , Exercise*/physiology, Humans ; Male ; Female ; Longitudinal Studies ; Thigh/diagnostic imaging ; Middle Aged ; Follow-Up Studies ; Aged ; Organ Size

Pre-conception weight loss interventions in women with polycystic ovary syndrome and the effect on perinatal outcomes: A quantitative synthesis of surrogate outcomes.

Autoren: Fernandes A Gordon A Sweeting A

Quelle: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Dec; Vol. 27 (12), pp. 7158-7179. Date of Electronic Publication: 2025 Oct 01.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

MeSH-Schlagworte: Polycystic Ovary Syndrome*/complications , Polycystic Ovary Syndrome*/therapy , Pregnancy Outcome*/epidemiology , Weight Loss* , Preconception Care*/methods , Obesity*/therapy , Obesity*/complications , Weight Reduction Programs*/methods , Pregnancy Complications*/prevention & control, Humans ; Female ; Pregnancy ; Randomized Controlled Trials as Topic ; Body Mass Index ; Overweight/therapy ; Overweight/complications ; Pregnancy Rate ; Adult

Lactational high weight loss impairs follicular development by causing mitochondrial dysfunction of ovarian cells in sows and mitigated by butyrate supplement.

Autoren: Liu K Zhang L Xu X et al.

Quelle: Journal of advanced research [J Adv Res] 2025 Dec; Vol. 78, pp. 11-28. Date of Electronic Publication: 2025 Jan 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cairo University, production and hosting by Elsevier B. V Country of Publication: Egypt NLM ID: 101546952 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2090-1224 (Electronic) Linking ISSN: 20901224 NLM ISO Abbreviation: J Adv Res Subsets: MEDLINE

MeSH-Schlagworte: Mitochondria*/metabolism , Mitochondria*/drug effects , Mitochondria*/pathology , Butyrates*/pharmacology , Lactation*/physiology , Ovarian Follicle*/drug effects , Ovarian Follicle*/metabolism , Weight Loss*/physiology, Animals ; Female ; Swine ; Mice ; Dietary Supplements ; Ovary/metabolism ; Ovary/drug effects ; Granulosa Cells/metabolism ; Granulosa Cells/drug effects

Effects of Resmetirom on Metabolic-Dysfunction Associated Steatohepatitis in Patients With Weight Loss and/or Diabetes Taking Glucagon-Like Peptide-1 Receptor Agonists and Other Diabetes Therapies: A Secondary Analysis of the MAESTRO-NASH Trial.

Autoren: Noureddin M Rinella M Taub R et al.

Quelle: Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2025 Dec; Vol. 62 (11-12), pp. 1089-1099. Date of Electronic Publication: 2025 Oct 23.

Publikationsart: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8707234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2036 (Electronic) Linking ISSN: 02692813 NLM ISO Abbreviation: Aliment Pharmacol Ther Subsets: MEDLINE

MeSH-Schlagworte: Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/complications , Weight Loss*/drug effects , Glucagon-Like Peptide-1 Receptor Agonists* , Hypoglycemic Agents*/therapeutic use , Non-alcoholic Fatty Liver Disease*/drug therapy , Fatty Liver*/drug therapy, Humans ; Male ; Female ; Middle Aged ; Double-Blind Method ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Treatment Outcome ; Adult ; Liver Cirrhosis/drug therapy ; Aged

Trait-like stability of sweet food preferences during diet-induced weight loss in women with overweight and obesity: Evidence from the Leeds food preference questionnaire.

Autoren: Dominic O Nuno C Pauline O et al.

Quelle: Physiology & behavior [Physiol Behav] 2025 Dec 01; Vol. 302, pp. 115098. Date of Electronic Publication: 2025 Sep 09.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0151504 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-507X (Electronic) Linking ISSN: 00319384 NLM ISO Abbreviation: Physiol Behav Subsets: MEDLINE

MeSH-Schlagworte: Food Preferences*/physiology , Food Preferences*/psychology , Obesity*/diet therapy , Obesity*/psychology , Overweight*/diet therapy , Overweight*/psychology , Weight Loss*/physiology, Humans ; Female ; Adult ; Surveys and Questionnaires ; Middle Aged

First report on a case series of Patulous Eustachian tube following GLP-1 receptor agonist-induced weight loss.

Autoren: Sudhoff H; Department of Otorhinolaryngology, Head and Neck Surgery, Kopfzentrum Bielefeld, Am Stadtholz 39, 33609, Bielefeld, Germany. holger.sudhoff@kopfzentrum-bielefeld.de.; University of Barcelona Medical School, Villaroel 170, Esc,.8, 2 A, Barcelona, 08036, Spain. holger.sudhoff@kopfzentrum-bielefeld.de.; Bielefeld ENT Institute (BENTI), Bielefeld, Germany. holger.sudhoff@kopfzentrum-bielefeld.de.

Quelle: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2025 Dec; Vol. 282 (12), pp. 6533-6538. Date of Electronic Publication: 2025 Jul 28.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Springer International Country of Publication: Germany NLM ID: 9002937 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-4726 (Electronic) Linking ISSN: 09374477 NLM ISO Abbreviation: Eur Arch Otorhinolaryngol Subsets: MEDLINE

MeSH-Schlagworte: Eustachian Tube*/drug effects , Weight Loss*/drug effects , Glucagon-Like Peptide-1 Receptor Agonists* , Ear Diseases*/chemically induced , Ear Diseases*/diagnosis , Hypoglycemic Agents*/adverse effects, Humans ; Adult ; Female ; Male ; Middle Aged ; Retrospective Studies

Influence of Weight Loss and Weight Regain on Adipose Tissue Inflammation.

Autoren: Caceres L Guha Ray A Emont MP et al.

Quelle: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2025 Dec; Vol. 45 (12), pp. 2155-2163. Date of Electronic Publication: 2025 Oct 02.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

MeSH-Schlagworte: Weight Gain* , Weight Loss* , Obesity*/physiopathology , Obesity*/metabolism , Obesity*/therapy , Obesity*/immunology , Obesity*/complications , Adipose Tissue*/metabolism , Adipose Tissue*/physiopathology , Adipose Tissue*/immunology , Adipose Tissue*/pathology , Inflammation*/physiopathology , Inflammation*/metabolism , Inflammation*/immunology, Humans ; Animals ; Inflammation Mediators/metabolism ; Risk Factors ; Insulin Resistance ; Cardiovascular Diseases/physiopathology ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/metabolism

Impact of body weight changes on adverse events and treatment outcomes during R-CHOP chemotherapy for non-Hodgkin's lymphoma.

Autoren: Kushihara H Osumi M Okumura H et al.

Quelle: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [Support Care Cancer] 2025 Nov 27; Vol. 33 (12), pp. 1139. Date of Electronic Publication: 2025 Nov 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Country of Publication: Germany NLM ID: 9302957 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-7339 (Electronic) Linking ISSN: 09414355 NLM ISO Abbreviation: Support Care Cancer Subsets: MEDLINE

MeSH-Schlagworte: Antineoplastic Combined Chemotherapy Protocols*/adverse effects , Antineoplastic Combined Chemotherapy Protocols*/administration & dosage , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Lymphoma, Non-Hodgkin*/drug therapy , Weight Loss*/drug effects, Humans ; Female ; Male ; Doxorubicin/adverse effects ; Doxorubicin/administration & dosage ; Doxorubicin/therapeutic use ; Retrospective Studies ; Vincristine/adverse effects ; Vincristine/administration & dosage ; Vincristine/therapeutic use ; Cyclophosphamide/adverse effects ; Cyclophosphamide/administration & dosage ; Cyclophosphamide/therapeutic use ; Middle Aged ; Prednisone/adverse effects ; Prednisone/administration & dosage ; Prednisone/therapeutic use ; Rituximab/adverse effects ; Rituximab/administration & dosage ; Rituximab/therapeutic use ; Aged ; Adult ; Treatment Outcome ; Proportional Hazards Models

Individual response to lifestyle interventions: a pooled analysis of three long-term weight loss trials.

Autoren: Yaskolka Meir A Tsaban G Rinott E et al.

Quelle: European journal of preventive cardiology [Eur J Prev Cardiol] 2025 Nov 11; Vol. 32 (16), pp. 1660-1670.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 101564430 Publication Model: Print Cited Medium: Internet ISSN: 2047-4881 (Electronic) Linking ISSN: 20474873 NLM ISO Abbreviation: Eur J Prev Cardiol Subsets: MEDLINE

MeSH-Schlagworte: Weight Loss* , Risk Reduction Behavior* , Obesity*/therapy , Obesity*/physiopathology , Obesity*/diagnosis , Obesity*/blood , Healthy Lifestyle* , Weight Reduction Programs* , Cardiovascular Diseases*/prevention & control, Humans ; Male ; Female ; Middle Aged ; Time Factors ; Treatment Outcome ; Adult ; Biomarkers/blood ; Life Style ; Cardiometabolic Risk Factors ; Randomized Controlled Trials as Topic ; Adiposity

Examining changes in neurofilament light chain following a behavioral weight loss intervention for adults with multiple sclerosis and obesity.

Autoren: Cozart JS Bruce AS Shook RP et al.

Quelle: Multiple sclerosis and related disorders [Mult Scler Relat Disord] 2025 Nov; Vol. 103, pp. 106671. Date of Electronic Publication: 2025 Aug 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier B. V Country of Publication: Netherlands NLM ID: 101580247 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-0356 (Electronic) Linking ISSN: 22110348 NLM ISO Abbreviation: Mult Scler Relat Disord Subsets: MEDLINE

MeSH-Schlagworte: Neurofilament Proteins*/metabolism , Neurofilament Proteins*/blood , Multiple Sclerosis*/complications , Multiple Sclerosis*/therapy , Multiple Sclerosis*/metabolism , Obesity*/therapy , Obesity*/complications , Obesity*/metabolism , Weight Reduction Programs*/methods , Weight Loss*/physiology , Behavior Therapy*, Humans ; Male ; Female ; Adult ; Middle Aged ; Cross-Sectional Studies ; Exercise ; Longitudinal Studies