Výsledky vyhľadávania - "Virus Replication/drug effects"

Efficient and robust reverse genetics system for bovine rotavirus generation and its application for antiviral screening

Autori: Qin, Songkang Li, Kuan-Hao Liu, Ben-Jin a ďalší

Zdroj: Virol Sin

Predmety: Rotavirus, Rotavirus/drug effects, High-throughput screen, Immunology, Green Fluorescent Proteins, Drug Evaluation, Preclinical, Small chemical compound, Genome, Viral, Viral Nonstructural Proteins, Virus Replication, Antiviral Agents, Green Fluorescent Proteins/genetics, Rotavirus Infections, Cell Line, Veterinary medicine & animal health, Reverse Genetics/methods, NSP3 protein, Rotavirus, Virology, Cricetinae, Animals, Bovine rotavirus (BRV), Rotavirus Infections/virology, Plasmids/genetics, Virus Replication/drug effects, Reporter virus, Life sciences, Médecine vétérinaire & santé animale, Reverse Genetics, Viral Nonstructural Proteins/genetics, Infectious Diseases, Optimized reverse genetics system, Rotavirus/genetics, Sciences du vivant, Molecular Medicine, Cattle, Drug Evaluation, Preclinical/methods, Research Article, Plasmids

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39349279

Identification of pan-flavivirus compounds from drug repurposing

Autori: Fatima Zahra Lissane Eddine Gregory Mathez Vincent Carlen a ďalší

Zdroj: Antiviral research, vol. 240, pp. 106205

Predmety: Antiviral Agents/pharmacology, Drug Repositioning, Humans, Virus Replication/drug effects, Animals, Cell Line, Flavivirus/drug effects, Drug Resistance, Viral, Drug-reporposing, Pan-flavivirus, Protein protein interaction, Replication inhibitor

Popis súboru: application/pdf

Prístupová URL adresa: http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1FF761DEFB773
https://serval.unil.ch/notice/serval:BIB_1FF761DEFB77
https://serval.unil.ch/resource/serval:BIB_1FF761DEFB77.P001/REF.pdf

Targeting PI4KB and Src/Abl host kinases as broad-spectrum antiviral strategy: Myth or real opportunity?

Autori: Martina, M.G. Rubini, D. Radi, M. a ďalší

Zdroj: Antiviral research, vol. 235, pp. 106100

Predmety: Antiviral Agents/pharmacology, Humans, src-Family Kinases/antagonists & inhibitors, Protein Kinase Inhibitors/pharmacology, Proto-Oncogene Proteins c-abl/antagonists & inhibitors, 1-Phosphatidylinositol 4-Kinase/antagonists & inhibitors, 1-Phosphatidylinositol 4-Kinase/metabolism, Virus Diseases/drug therapy, Animals, Virus Replication/drug effects, Broad-spectrum, Host-targeted antivirals,PI4KB, Kinase, Preparedness, Src/Abl

Popis súboru: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/39922541; info:eu-repo/semantics/altIdentifier/eissn/1872-9096; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_365893306FCB3; https://serval.unil.ch/notice/serval:BIB_365893306FCB; https://serval.unil.ch/resource/serval:BIB_365893306FCB.P001/REF.pdf

Dostupnosť: https://serval.unil.ch/notice/serval:BIB_365893306FCB
https://doi.org/10.1016/j.antiviral.2025.106100
https://serval.unil.ch/resource/serval:BIB_365893306FCB.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_365893306FCB3

The structure of lipopeptides impacts their antiviral activity and mode of action against SARS-CoV-2 in vitro

Autori: Hoste, Alexis Smeralda, Willy Cugnet, Aurélien a ďalší

Zdroj: Appl Environ Microbiol

Predmety: Lipopeptides/pharmacology, 0301 basic medicine, Antiviral Agents/chemistry, Biotechnologie, Structure-activity relationships, Antiviral Agents/pharmacology, Biochimie, biophysique & biologie moléculaire, Virus Replication, surfactin, White lines, Applied Microbiology and Biotechnology, Antiviral Agents, Veterinary medicine & animal health, Lipopeptides, Structure-Activity Relationship, 03 medical and health sciences, Chlorocebus aethiops, Surfactins, Animals, Humans, caspofungin, Vero Cells, COVID-19/virology, Virus Replication/drug effects, 0303 health sciences, Ecology, SARS-CoV-2, structure-activity relationship, fengycin, Severe acute respiratory syndrome coronavirus, COVID-19, Fengycins, Antivirals, antiviral, lipopeptides, Life sciences, Médecine vétérinaire & santé animale, White line-inducing principle, Sciences du vivant, cytotoxicity, Antiviral activities, SARS-CoV-2/drug effects, Lipopeptides/chemistry, WLIP, Food Science, Biochemistry, biophysics & molecular biology, Biotechnology

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39445780

Bithiazole inhibitors of PI4KB show broad-spectrum antiviral activity against different viral families.

Autori: Martina, M.G. Carlen, V. Van der Reysen, S. a ďalší

Zdroj: Antiviral research, vol. 231, pp. 106003

Predmety: Antiviral Agents/pharmacology, Humans, Animals, Virus Replication/drug effects, Thiazoles/pharmacology, Phosphotransferases (Alcohol Group Acceptor)/antagonists & inhibitors, Phosphotransferases (Alcohol Group Acceptor)/genetics, Picornaviridae/drug effects, Mice, RNA Viruses/drug effects

Popis súboru: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/39265657; info:eu-repo/semantics/altIdentifier/eissn/1872-9096; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_4C98CFE02CBF0; https://serval.unil.ch/notice/serval:BIB_4C98CFE02CBF; https://serval.unil.ch/resource/serval:BIB_4C98CFE02CBF.P001/REF.pdf

Dostupnosť: https://serval.unil.ch/notice/serval:BIB_4C98CFE02CBF
https://doi.org/10.1016/j.antiviral.2024.106003
https://serval.unil.ch/resource/serval:BIB_4C98CFE02CBF.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4C98CFE02CBF0

Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome

Autori: Nenad Ban Annika Kratzel Angus McMillan a ďalší

Zdroj: Science
Science, vol. 372, no. 6548, pp. 1306-1313
Science, 372 (6548)

Predmety: Models, Molecular, Ribosomal Proteins, Protein Folding, Animals, Antiviral Agents/pharmacology, Codon, Terminator, Coronavirus RNA-Dependent RNA Polymerase/biosynthesis, Coronavirus RNA-Dependent RNA Polymerase/chemistry, Coronavirus RNA-Dependent RNA Polymerase/genetics, Cryoelectron Microscopy, Fluoroquinolones/pharmacology, Frameshifting, Ribosomal/drug effects, Genome, Viral, Humans, Image Processing, Computer-Assisted, Nucleic Acid Conformation, Open Reading Frames, RNA, Messenger/chemistry, RNA, Messenger/genetics, RNA, Messenger/metabolism, RNA, Ribosomal, 18S/chemistry, RNA, Ribosomal, 18S/genetics, RNA, Ribosomal, 18S/metabolism, RNA, Viral/chemistry, RNA, Viral/genetics, RNA, Viral/metabolism, Ribosomal Proteins/metabolism, Ribosomes/metabolism, Ribosomes/ultrastructure, SARS-CoV-2/drug effects, SARS-CoV-2/genetics, SARS-CoV-2/physiology, Viral Proteins/biosynthesis, Viral Proteins/chemistry, Viral Proteins/genetics, Virus Replication/drug effects, Coronavirus RNA-Dependent RNA Polymerase, SARS-CoV-2, Frameshifting, Ribosomal, Antiviral Agents, 3. Good health, RNA, Ribosomal, 18S, RNA, Viral, RNA, Messenger, Ribosomes, Research Articles, Fluoroquinolones

Popis súboru: application/pdf; application/application/pdf

Prístupová URL adresa: https://www.science.org/cms/asset/87f1b0ff-c027-4948-94a3-d81fc0f181c8/pap.pdf
https://pubmed.ncbi.nlm.nih.gov/34029205
https://serval.unil.ch/resource/serval:BIB_AA30EA09AC1E.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_AA30EA09AC1E1
https://serval.unil.ch/notice/serval:BIB_AA30EA09AC1E
http://hdl.handle.net/20.500.11850/491269

Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc

Autori: Chaillon, Antoine Gianella, Sara Lada, Steven M a ďalší

Zdroj: Journal of Virology. 92(3)

Predmety: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 3204 Immunology (for-2020), Infectious Diseases (rcdc), HIV/AIDS (rcdc), Sexually Transmitted Infections (rcdc), Genetics (rcdc), 6.1 Pharmaceuticals (hrcs-rac), Infection (hrcs-hc), 3 Good Health and Well Being (sdg), Adult (mesh), Antiretroviral Therapy, Highly Active (mesh), Bayes Theorem (mesh), CCR5 Receptor Antagonists (mesh), California (mesh), Cyclohexanes (mesh), DNA, Viral (mesh), Double-Blind Method (mesh), Female (mesh), HIV Infections (mesh), HIV-1 (mesh), Humans (mesh), Male (mesh), Maraviroc (mesh), RNA, Viral (mesh), Triazoles (mesh), Viral Load (mesh), Viremia (mesh), Virus Replication (mesh), Young Adult (mesh), ART intensification, evolution, HIV, maraviroc, reservoir, Humans (mesh), HIV-1 (mesh), Viremia (mesh), HIV Infections (mesh), Cyclohexanes (mesh), Triazoles (mesh), DNA, Viral (mesh), RNA, Viral (mesh), Antiretroviral Therapy, Highly Active (mesh), Viral Load (mesh), Bayes Theorem (mesh), Double-Blind Method (mesh), Virus Replication (mesh), Adult (mesh), California (mesh), Female (mesh), Male (mesh), Young Adult (mesh), CCR5 Receptor Antagonists (mesh), Maraviroc (mesh), ART intensification, HIV, evolution, maraviroc, reservoir, Adult (mesh), Antiretroviral Therapy, Highly Active (mesh), Bayes Theorem (mesh), CCR5 Receptor Antagonists (mesh), California (mesh), Cyclohexanes (mesh), DNA, Viral (mesh), Double-Blind Method (mesh), Female (mesh), HIV Infections (mesh), HIV-1 (mesh), Humans (mesh), Male (mesh), Maraviroc (mesh), RNA, Viral (mesh), Triazoles (mesh), Viral Load (mesh), Viremia (mesh), Virus Replication (mesh), Young Adult (mesh), Adult Antiretroviral Therapy, Highly Active Bayes Theorem CCR5 Receptor Antagonists/*therapeutic use California Cyclohexanes/*therapeutic use DNA, Viral/blood Double-Blind Method Female HIV Infections/*drug therapy/virology HIV-1/genetics/physiology Humans Male Maraviroc RNA, Viral/blood Triazoles/*therapeutic use Viral Load Viremia/*drug therapy Virus Replication/*drug effects Young Adult *ART intensification *Hiv *evolution *maraviroc *reservoir, 06 Biological Sciences (for), 07 Agricultural and Veterinary Sciences (for), 11 Medical and Health Sciences (for), Virology (science-metrix), 30 Agricultural, veterinary and food sciences (for-2020), 31 Biological sciences (for-2020), 32 Biomedical and clinical sciences (for-2020)

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/2dz5q4q8
https://escholarship.org/content/qt2dz5q4q8/qt2dz5q4q8.pdf

Interferon‐stimulated gene products as regulators of central carbon metabolism

Autori: Ebrahimi, Kourosh H. Gilbert‐Jaramillo, Javier James, William S. a ďalší

Zdroj: FEBS J
The FEBS Journal

Predmety: 0301 basic medicine, Oxidoreductases Acting on CH-CH Group Donors, S-Adenosylmethionine, Cells, COVID-19/prevention & control, Induced Pluripotent Stem Cells, Virus Replication, Biochemistry, Antiviral Agents, Models, Biological, 03 medical and health sciences, Viewpoint, Models, Macrophages/metabolism, Humans, Molecular Biology, Cells, Cultured, Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)/metabolism, Virus Replication/drug effects, Cultured, SARS-CoV-2, Antiviral Agents/metabolism, Macrophages, Immunity, COVID-19, Proteins, Cell Biology, Biological, S-Adenosylmethionine/metabolism, Carbon, Immunity, Innate, 3. Good health, Induced Pluripotent Stem Cells/metabolism, Innate/drug effects, HEK293 Cells, Proteins/genetics, Carbon/metabolism, Interferons, Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating), SARS-CoV-2/drug effects, Interferons/metabolism

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33185982
https://www.cardioscience.ox.ac.uk/publications/1146908
https://www.immunology.ox.ac.uk/publications/1146908
https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15625
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/febs.15625
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359365/
https://pubmed.ncbi.nlm.nih.gov/33185982/
https://ora.ox.ac.uk/objects/uuid:56a11192-933b-4ad0-86f8-08cc4bebe30d
https://doi.org/10.1111/febs.15625

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Autori: Ko Yung Sit Ren Sun Raveen Rathnasinghe a ďalší

Zdroj: Nature, vol 586, iss 7827
Nature

Predmety: 0301 basic medicine, Coronaviruses, 302091 Immuntherapie, Drug Evaluation, Preclinical, Gene Expression Regulation/drug effects, Alveolar Epithelial Cells/cytology, Virus Replication, POSTMENOPAUSAL OSTEOPOROSIS, Morpholines/analysis, ONO-5334, Coronaviruses Therapeutics and Interventions, Induced Pluripotent Stem Cells/cytology, PIKFYVE, Models, 302091 Immunotherapy, Viral, 106052 Cell biology, Lung, 106022 Mikrobiologie, 0303 health sciences, Multidisciplinary, Betacoronavirus/drug effects, Alanine, Triazines, APILIMOD, Drug Synergism, Alanine/analogs & derivatives, Preclinical, Triazines/analysis, 3. Good health, EBOLA-VIRUS, Infectious Diseases, Medical Microbiology, 5.1 Pharmaceuticals, SDG 3 – Gesundheit und Wohlergehen, Pneumonia & Influenza, 106022 Microbiology, 106052 Zellbiologie, Drug, Infection, Coronavirus Infections, General Science & Technology, Morpholines, Induced Pluripotent Stem Cells, Cysteine Proteinase Inhibitors, Antiviral Agents, Models, Biological, Adenosine Monophosphate/analogs & derivatives, Cell Line, Small Molecule Libraries, Dose-Response Relationship, Betacoronavirus, 03 medical and health sciences, Rare Diseases, SDG 3 - Good Health and Well-being, Antiviral Agents/analysis, Small Molecule Libraries/analysis, KINASE, Humans, Viral/drug therapy, Pandemics, Virus Replication/drug effects, Biomedical and Clinical Sciences, Dose-Response Relationship, Drug, SARS-CoV-2, Drug Repositioning, Hydrazones, Reproducibility of Results, COVID-19, Coronavirus Infections/drug therapy, Pneumonia, Virus Internalization, Stem Cell Research, Biological, EFFICACY, Adenosine Monophosphate, COVID-19 Drug Treatment, Virus Internalization/drug effects, Good Health and Well Being, Orphan Drug, Emerging Infectious Diseases, Pyrimidines, IL-12/IL-23 INHIBITOR, Gene Expression Regulation, CATHEPSIN-L, Alveolar Epithelial Cells, REPLICATION, Drug Evaluation, Cysteine Proteinase Inhibitors/analysis

Popis súboru: application/pdf

Prístupová URL adresa: https://www.nature.com/articles/s41586-020-2577-1.pdf
https://pubmed.ncbi.nlm.nih.gov/32707573
https://ucrisportal.univie.ac.at/de/publications/5e0e71b3-7b21-41ba-a0f2-eddf86ce60e7
https://doi.org/10.1038/s41586-020-2577-1
http://vlib.kmu.ac.ir/kmu/handle/kmu/891293
http://vlib.kmu.ac.ir/kmu/handle/kmu/912560
https://escholarship.org/content/qt6p88f41f/qt6p88f41f.pdf
https://escholarship.org/uc/item/6p88f41f

Can research at the end of life be a useful tool to advance HIV cure?

Autori: Gianella, Sara Taylor, Jeff Brown, Timothy R a ďalší

Zdroj: AIDS. 31(1)

Predmety: Biomedical and Clinical Sciences, Health Sciences, Anti-HIV Agents, Biomedical Research, Clinical Trials as Topic, HIV, HIV Infections, Humans, Terminally Ill, Virus Replication, end of life, eradication, HIV cure, last gift, legacy, peri-mortem research model, research, Anti-HIV Agents/*therapeutic use Biomedical Research/*methods/trends *Clinical Trials as Topic HIV/drug effects/*growth & development HIV Infections/*drug therapy/virology Humans *Terminally Ill Virus Replication/*drug effects, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Virology, Biomedical and clinical sciences, Health sciences

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/7sq88797
https://escholarship.org/content/qt7sq88797/qt7sq88797.pdf

Influence of host cell type and V3 loop of the surface glycoprotein on susceptibility of human immunodeficiency virus type 1 to polyanion compounds

Autori: Meylan, P. R. Kornbluth, R. S. Zbinden, I. a ďalší

Predmety: Cell Line Dextran Sulfate/*pharmacology HIV Envelope Protein gp120/*physiology HIV-1/*drug effects Heparin/*pharmacology Humans Virus Replication/drug effects

Relation: Antimicrobial Agents and Chemotherapy; https://iris.unil.ch/handle/iris/67915; serval:BIB_5594DEB3AA71; A1994PU60300039; 7695283

Dostupnosť: https://iris.unil.ch/handle/iris/67915

The Antiviral Activity of the Cellular Glycoprotein LGALS3BP/90K Is Species Specific.

Autori: Lodermeyer, V. Ssebyatika, G. Passos, V. a ďalší

Predmety: Amino Acid Sequence, Animals, Antigens, Neoplasm/chemistry, Neoplasm/pharmacology, Antiviral Agents/pharmacology, Biomarkers, Tumor/chemistry, Tumor/pharmacology, Carrier Proteins/chemistry, Carrier Proteins/pharmacology, Gene Products, env/metabolism, Glycoproteins/chemistry, Glycoproteins/pharmacology, HIV Infections/drug therapy, HIV Infections/virology, HIV-1/drug effects, Humans, Macaca mulatta, Protein Conformation, Sequence Homology, Simian Acquired Immunodeficiency Syndrome/drug therapy, Simian Acquired Immunodeficiency Syndrome/virology, Simian Immunodeficiency Virus/drug effects, Species Specificity, Virus Assembly/drug effects, Virus Replication/drug effects, antiviral, human immunodeficiency virus

Popis súboru: application/pdf

Relation: Journal of Virology; https://iris.unil.ch/handle/iris/47749; serval:BIB_46A7AAA28FE7; 000437375800007

Dostupnosť: https://iris.unil.ch/handle/iris/47749
https://doi.org/10.1128/JVI.00226-18

Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication

Autori: Romero, D. L. Busso, M. Tan, C. K. a ďalší

Predmety: Animals *Antiviral Agents Cell Survival/drug effects DNA, Viral/analysis Drug Synergism HIV-1/*drug effects/growth & development Mice Mice, Nude Piperazines/*pharmacology Polymerase Chain Reaction RNA, Viral/analysis *Reverse Transcriptase Inhibitors Thymine Nucleotides/pharmacology Virus Replication/drug effects Zidovudine/pharmacology

Relation: Proceedings of the National Academy of Sciences; https://iris.unil.ch/handle/iris/46542; serval:BIB_22739B079056; A1991GH80500108; 1717988

Dostupnosť: https://iris.unil.ch/handle/iris/46542
https://doi.org/10.1073/pnas.88.19.8806

Methylene Blue has a potent antiviral activity against SARS-CoV-2 and H1N1 influenza virus in the absence of UV-activation in vitro.

Autori: Cagno, V. Medaglia, C. Cerny, A. a ďalší

Predmety: Animals, COVID-19/drug therapy, COVID-19/genetics, COVID-19/virology, Chlorocebus aethiops, Humans, Influenza, Human/drug therapy, Human/genetics, Human/virology, Methylene Blue/pharmacology, SARS-CoV-2/drug effects, SARS-CoV-2/pathogenicity, Ultraviolet Rays/adverse effects, Vero Cells, Virus Inactivation/drug effects, Virus Inactivation/radiation effects, Virus Replication/drug effects, Virus Replication/radiation effects

Popis súboru: application/pdf

Relation: Scientific Reports; https://iris.unil.ch/handle/iris/209821; serval:BIB_B5A1C7ABFC3D; 000677492900002

Dostupnosť: https://iris.unil.ch/handle/iris/209821
https://doi.org/10.1038/s41598-021-92481-9

Mechanisms for the inhibition of HIV replication by interferons-alpha, -beta, and -gamma in primary human macrophages

Autori: Meylan, P. R. Guatelli, J. C. Munis, J. R. a ďalší

Predmety: Cells, Cultured DNA, Viral/genetics Genes, Viral/genetics HIV/*drug effects/genetics/physiology HIV Core Protein p24/analysis Humans Interferon Type II/pharmacology Interferon-alpha/pharmacology Interferon-beta/pharmacology Interferons/*pharmacology Macrophages/*microbiology Polymerase Chain Reaction RNA, Messenger/genetics RNA, Viral/genetics Virus Replication/*drug effects/physiology

Relation: Virology; https://iris.unil.ch/handle/iris/185585; serval:BIB_C929C9FA7201; A1993KN05700014; 7679856

Dostupnosť: https://iris.unil.ch/handle/iris/185585
https://doi.org/10.1006/viro.1993.1110

Deleterious impact of a virulent bacteriophage on survival and biocontrol activity of Pseudomonas fluorescens strain CHAO in natural soil.

Autori: Keel, C. Ucurum, Z. Michaux, P. a ďalší

Predmety: Bacteriophages/genetics, Bacteriophages/pathogenicity, Chloroform/pharmacology, Cucumis sativus/genetics, Cucumis sativus/microbiology, DNA, Viral/genetics, Hot Temperature, Immunity, Innate/genetics, Microscopy, Electron, Pest Control, Biological/methods, Plant Diseases/microbiology, Plant Roots/microbiology, Pseudomonas fluorescens/genetics, Pseudomonas fluorescens/virology, Soil Microbiology, Ultraviolet Rays, Virulence, Virus Replication/drug effects, Virus Replication/radiation effects

Relation: Molecular Plant-Microbe Interactions; https://iris.unil.ch/handle/iris/179380; serval:BIB_C7B4FB4152AC; 000175938200007

Dostupnosť: https://iris.unil.ch/handle/iris/179380
https://doi.org/10.1094/MPMI.2002.15.6.567

Virological outcome and management of persistent low-level viraemia in HIV-1-infected patients: 11 years of the Swiss HIV Cohort Study.

Autori: Boillat-Blanco, N. Darling, K.E. Schoni-Affolter, F. a ďalší

Prispievatelia: Boillat-Blanco, N. Darling, K.E. Schoni-Affolter, F. a ďalší

Predmety: Adult, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Disease Management, Female, HIV Infections/drug therapy, HIV Infections/immunology, HIV Protease Inhibitors/therapeutic use, HIV-1/drug effects, HIV-1/physiology, Humans, Male, Middle Aged, Retrospective Studies, Reverse Transcriptase Inhibitors/therapeutic use, Switzerland, Treatment Outcome, Viral Load/drug effects, Viremia/drug therapy, Viremia/immunology, Virus Replication/drug effects

Relation: Antiviral Therapy; https://iris.unil.ch/handle/iris/156321; serval:BIB_EBE639128EA3; 000359909200007

Dostupnosť: https://iris.unil.ch/handle/iris/156321
https://doi.org/10.3851/IMP2815

Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals--the Swiss HIV Cohort Study.

Autori: Fehr, J. Glass, T.R. Louvel, S. a ďalší

Prispievatelia: Fehr, J. Glass, T.R. Louvel, S. a ďalší

Predmety: Adult, Anti-HIV Agents/pharmacology, Anti-HIV Agents/therapeutic use, Cohort Studies, Dose-Response Relationship, Drug, Drug Resistance, Viral/physiology, Female, Genotype, HIV Infections/diagnosis, HIV Infections/drug therapy, HIV-1/physiology, Humans, Male, Microbial Sensitivity Tests/methods, Middle Aged, Phenotype, Predictive Value of Tests, Prognosis, Switzerland, Virus Replication/drug effects, Virus Replication/physiology

Popis súboru: application/pdf

Relation: Journal of Translational Medicine; https://iris.unil.ch/handle/iris/150304; serval:BIB_74E4E7A9A6E7; 000286835700001

Dostupnosť: https://iris.unil.ch/handle/iris/150304
https://doi.org/10.1186/1479-5876-9-14

HIV rebounds from latently infected cells, rather than from continuing low-level replication.

Autori: Joos, B. Fischer, M. Kuster, H. a ďalší

Prispievatelia: Joos, B. Fischer, M. Kuster, H. a ďalší

Predmety: Cells, Cultured, Genetic Variation, HIV/genetics, HIV/physiology, HIV Infections/drug therapy, HIV Infections/virology, Humans, Molecular Sequence Data, Phylogeny, Receptors, CXCR4, HIV, Virus Activation, Virus Latency/drug effects, Virus Replication/drug effects

Relation: Proceedings of the National Academy of Sciences; https://iris.unil.ch/handle/iris/137393; serval:BIB_CF6F06658C27; 000260913500058

Dostupnosť: https://iris.unil.ch/handle/iris/137393
https://doi.org/10.1073/pnas.0804192105

A mutation in the gene encoding the vaccinia virus 37,000-M(r) protein confers resistance to an inhibitor of virus envelopment and release.

Autori: Schmutz, C. Payne, L.G. Gubser, J. a ďalší

Predmety: Amino Acid Sequence, Animals, Base Sequence, Cells, Cultured, Drug Resistance, Microbial, Genes, Viral, Isoniazid/analogs &, derivatives, Isoniazid/pharmacology, Molecular Sequence Data, Molecular Weight, Mutation, Plaque Assay, Rabbits, Restriction Mapping, Vaccinia virus/genetics, Viral Envelope Proteins/chemistry, Viral Envelope Proteins/genetics, Viral Structural Proteins/genetics, Virus Replication/drug effects

Relation: Journal of Virology; 0022-538X[print], 0022-538X[linking]; https://iris.unil.ch/handle/iris/134188; serval:BIB_991FD2CB63A0; A1991FQ94000004; 2041074

Dostupnosť: https://iris.unil.ch/handle/iris/134188