Suchergebnisse - "Vascular Remodeling"

Impact of Blood Pressure Self-Management on Vascular Remodeling After Hypertensive Pregnancy.

Autoren: Kitt J Biasiolli L Krasner S et al.

Quelle: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2025 Nov; Vol. 82 (11), pp. 1938-1947. Date of Electronic Publication: 2025 Sep 04.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE

MeSH-Schlagworte: Vascular Remodeling*/physiology , Vascular Remodeling*/drug effects , Antihypertensive Agents*/therapeutic use , Self-Management*/methods , Blood Pressure*/physiology , Blood Pressure*/drug effects , Hypertension, Pregnancy-Induced*/physiopathology , Hypertension, Pregnancy-Induced*/drug therapy, Humans ; Female ; Pregnancy ; Adult ; Prospective Studies ; Pulse Wave Analysis/methods ; Postpartum Period/physiology ; Vascular Stiffness/physiology ; Blood Pressure Determination/methods

PDZK1 Regulates the Stability and Function of ADRB2 to Prevent Vascular Remodelling in Hypertension.

Autoren: Zhang H Meng Y Li D et al.

Quelle: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2025 Dec; Vol. 52 (12), pp. e70085.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: Australia NLM ID: 0425076 Publication Model: Print Cited Medium: Internet ISSN: 1440-1681 (Electronic) Linking ISSN: 03051870 NLM ISO Abbreviation: Clin Exp Pharmacol Physiol Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Adrenergic, beta-2*/metabolism , Hypertension*/metabolism , Hypertension*/pathology , Hypertension*/physiopathology , Vascular Remodeling*/drug effects , Vascular Remodeling*/physiology , Carrier Proteins*/metabolism , Carrier Proteins*/genetics, Animals ; Mice, Knockout ; Mice ; Angiotensin II/pharmacology ; Humans ; Muscle, Smooth, Vascular/metabolism ; Protein Stability ; Male ; Ubiquitination ; Mice, Inbred C57BL ; Vasodilation ; beta-Arrestins

Cinnamaldehyde alleviates pulmonary hypertension by affecting vascular remodeling through the TLR4/NF-kB/HIF-1a pathway.

Autoren: Zhang J Zhang W Yang Z et al.

Quelle: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2025 Dec; Vol. 47 (1), pp. 2486829. Date of Electronic Publication: 2025 Apr 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9305929 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6006 (Electronic) Linking ISSN: 10641963 NLM ISO Abbreviation: Clin Exp Hypertens Subsets: MEDLINE

MeSH-Schlagworte: Toll-Like Receptor 4*/metabolism , Acrolein*/analogs & derivatives , Acrolein*/pharmacology , NF-kappa B*/metabolism , Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism , Vascular Remodeling*/drug effects , Hypertension, Pulmonary*/drug therapy , Hypertension, Pulmonary*/metabolism , Pulmonary Arterial Hypertension*/drug therapy , Pulmonary Arterial Hypertension*/metabolism, Animals ; Rats ; Male ; Signal Transduction/drug effects ; Rats, Sprague-Dawley ; Pulmonary Artery/drug effects ; Pulmonary Artery/metabolism ; Pulmonary Artery/pathology ; Disease Models, Animal

Impact of drug-coated balloon for vascular luminal dilatational remodeling after balloon angioplasty in intracranial atherosclerotic stenosis - a retrospective cohort study.

Autoren: Ding Q He Y Zhao J et al.

Quelle: Journal of neurointerventional surgery [J Neurointerv Surg] 2025 Nov 18; Vol. 17 (12), pp. 1314-1319. Date of Electronic Publication: 2025 Nov 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101517079 Publication Model: Electronic Cited Medium: Internet ISSN: 1759-8486 (Electronic) Linking ISSN: 17598478 NLM ISO Abbreviation: J Neurointerv Surg Subsets: MEDLINE

MeSH-Schlagworte: Intracranial Arteriosclerosis*/surgery , Intracranial Arteriosclerosis*/diagnostic imaging , Intracranial Arteriosclerosis*/therapy , Angioplasty, Balloon*/methods , Angioplasty, Balloon*/instrumentation , Vascular Remodeling*/physiology , Vascular Remodeling*/drug effects, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Aged ; Cohort Studies ; Treatment Outcome ; Follow-Up Studies ; Constriction, Pathologic

Complement C3 in panvascular disease: a central integrator of immune signaling and vascular remodeling.

Autoren: Li Y Zeng H Zhong X

Quelle: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2025 Nov 04; Vol. 139 (21).

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE

MeSH-Schlagworte: Vascular Remodeling*/immunology , Signal Transduction* , Complement C3*/metabolism , Complement C3*/immunology , Vascular Diseases*/immunology , Vascular Diseases*/pathology , Vascular Diseases*/metabolism, Humans ; Animals

Fucoxanthin ameliorates vascular remodeling via attenuating oxidative stress in hypoxic pulmonary hypertension rats.

Autoren: Zheng X Zhao J Jia X et al.

Quelle: The Journal of nutritional biochemistry [J Nutr Biochem] 2025 Nov; Vol. 145, pp. 110002. Date of Electronic Publication: 2025 Jun 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE

MeSH-Schlagworte: Xanthophylls*/pharmacology , Oxidative Stress*/drug effects , Vascular Remodeling*/drug effects , Hypertension, Pulmonary*/drug therapy , Hypertension, Pulmonary*/metabolism , Hypoxia*/complications, Animals ; Rats, Sprague-Dawley ; Male ; Rats ; Cell Proliferation/drug effects ; Pulmonary Artery/drug effects ; Pulmonary Artery/metabolism ; Antioxidants/pharmacology ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Reactive Oxygen Species/metabolism ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Superoxide Dismutase/metabolism ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism

The impact of chronic kidney disease on arteriovenous fistula remodeling: studies in a murine model of autosomal dominant polycystic kidney disease.

Autoren: Laboyrie SL Peters DJM Bijkerk R et al.

Quelle: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2025 Oct 01; Vol. 329 (4), pp. F453-F464. Date of Electronic Publication: 2025 Aug 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE

MeSH-Schlagworte: Polycystic Kidney, Autosomal Dominant*/physiopathology , Polycystic Kidney, Autosomal Dominant*/genetics , Polycystic Kidney, Autosomal Dominant*/pathology , Polycystic Kidney, Autosomal Dominant*/complications , Vascular Remodeling* , Arteriovenous Shunt, Surgical* , Renal Insufficiency, Chronic*/physiopathology , Renal Insufficiency, Chronic*/pathology , Kidney*/pathology , Kidney*/blood supply , Kidney*/physiopathology, Animals ; Disease Models, Animal ; Mice ; Male ; Mice, Inbred C57BL ; TRPP Cation Channels/genetics ; Blood Pressure

Maternal Diet-Induced Excess Adiposity in Mice Disrupts Mid-Gestation Decidual Immune and Vascular Homeostasis Without Impairing Spiral Artery Remodeling.

Autoren: Bellissimo CJ Yeo E Ribeiro TA et al.

Quelle: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2025 Dec; Vol. 241 (12), pp. e70130.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262545 Publication Model: Print Cited Medium: Internet ISSN: 1748-1716 (Electronic) Linking ISSN: 17481708 NLM ISO Abbreviation: Acta Physiol (Oxf) Subsets: MEDLINE

MeSH-Schlagworte: Decidua*/immunology , Decidua*/blood supply , Decidua*/metabolism , Diet, High-Fat*/adverse effects , Adiposity*/physiology , Vascular Remodeling*/physiology, Animals ; Female ; Pregnancy ; Mice ; Placenta/metabolism ; Placenta/immunology ; Mice, Inbred C57BL ; Homeostasis

PINK1/Parkin Deficiency Enhances Vascular Remodeling and Aggravates Hypoxia-induced Pulmonary Hypertension.

Autoren: Rehman R Dieffenbach P Vellarikkal SK et al.

Quelle: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2025 Dec; Vol. 73 (6), pp. 859-870.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: Vascular Remodeling* , Ubiquitin-Protein Ligases*/deficiency , Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , Protein Kinases*/deficiency , Protein Kinases*/metabolism , Protein Kinases*/genetics , Hypertension, Pulmonary*/pathology , Hypertension, Pulmonary*/etiology , Hypertension, Pulmonary*/metabolism , Hypertension, Pulmonary*/genetics , Hypoxia*/complications , Hypoxia*/pathology, Animals ; Humans ; Mice, Knockout ; Mitophagy ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Cell Proliferation ; Mice ; Muscle, Smooth, Vascular/pathology ; Muscle, Smooth, Vascular/metabolism ; Apoptosis ; Pulmonary Artery/pathology ; Pulmonary Artery/metabolism ; Male ; Mice, Inbred C57BL ; Mitochondria/metabolism

Anatomical characteristics are associated with aneurysm sac regression after endovascular repair.

Autoren: van Rijswijk RE Leeuwerke SJG Alblas D et al.

Quelle: Journal of vascular surgery [J Vasc Surg] 2025 Dec; Vol. 82 (6), pp. 2023-2035. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 8407742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6809 (Electronic) Linking ISSN: 07415214 NLM ISO Abbreviation: J Vasc Surg Subsets: MEDLINE

MeSH-Schlagworte: Aortic Aneurysm, Abdominal*/surgery , Aortic Aneurysm, Abdominal*/diagnostic imaging , Aortic Aneurysm, Abdominal*/pathology , Endovascular Procedures*/adverse effects , Blood Vessel Prosthesis Implantation*/adverse effects , Aorta, Abdominal*/diagnostic imaging , Aorta, Abdominal*/surgery , Vascular Remodeling*, Humans ; Male ; Female ; Retrospective Studies ; Aged ; Treatment Outcome ; Time Factors ; Risk Factors ; Aged, 80 and over ; Computed Tomography Angiography ; Aortography ; Middle Aged ; Predictive Value of Tests

Differences in aortic remodeling in patients with type 1a and type 5 endoleak who undergo salvage with fenestrated/branched endovascular aortic repair.

Autoren: Nguyen T Finnesgard E Patel S et al.

Quelle: Journal of vascular surgery [J Vasc Surg] 2025 Dec; Vol. 82 (6), pp. 1957-1965. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Journal Article; Comparative Study; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 8407742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6809 (Electronic) Linking ISSN: 07415214 NLM ISO Abbreviation: J Vasc Surg Subsets: MEDLINE

MeSH-Schlagworte: Endoleak*/diagnostic imaging , Endoleak*/surgery , Endoleak*/etiology , Endoleak*/physiopathology , Endovascular Procedures*/adverse effects , Endovascular Procedures*/instrumentation , Endovascular Procedures*/mortality , Blood Vessel Prosthesis Implantation*/adverse effects , Blood Vessel Prosthesis Implantation*/instrumentation , Blood Vessel Prosthesis Implantation*/mortality , Aortic Aneurysm, Abdominal*/surgery , Aortic Aneurysm, Abdominal*/diagnostic imaging , Aortic Aneurysm, Abdominal*/physiopathology , Vascular Remodeling* , Salvage Therapy*/adverse effects, Humans ; Male ; Retrospective Studies ; Aged ; Female ; Aged, 80 and over ; Risk Factors ; Time Factors ; Databases, Factual ; Treatment Outcome ; Blood Vessel Prosthesis ; Prosthesis Design ; Risk Assessment ; Endovascular Aneurysm Repair

Cocoa shell extract supplementation in hypertensive rats induces outward hypertrophic remodelling in mesenteric resistance arteries, reducing fibrosis.

Autoren: Rodríguez-Rodríguez P Ruvira S Abderrahim F et al.

Quelle: Experimental physiology [Exp Physiol] 2025 Dec; Vol. 110 (12), pp. 1838-1851. Date of Electronic Publication: 2025 May 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9002940 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-445X (Electronic) Linking ISSN: 09580670 NLM ISO Abbreviation: Exp Physiol Subsets: MEDLINE

MeSH-Schlagworte: Mesenteric Arteries*/drug effects , Mesenteric Arteries*/physiopathology , Mesenteric Arteries*/pathology , Hypertension*/physiopathology , Hypertension*/drug therapy , Vascular Remodeling*/drug effects , Plant Extracts*/pharmacology , Cacao*/chemistry , Vascular Resistance*/drug effects, Animals ; Male ; Female ; Rats ; Fibrosis ; Rats, Wistar ; Dietary Supplements ; Blood Pressure/drug effects ; Collagen/metabolism ; Hypertrophy ; Vasoconstriction/drug effects ; Vasodilation/drug effects ; Pregnancy

Finding a link between the TRPV4 ion channel and angiogenesis: a potential therapeutic target for vascular remodeling.

Autoren: Malka G Salucci V Bergdahl A

Quelle: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2025 Dec 01; Vol. 103 (12), pp. 409-417. Date of Electronic Publication: 2025 Nov 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 0372712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1205-7541 (Electronic) Linking ISSN: 00084212 NLM ISO Abbreviation: Can J Physiol Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: TRPV Cation Channels*/metabolism , TRPV Cation Channels*/agonists , TRPV Cation Channels*/antagonists & inhibitors , Vascular Remodeling*/drug effects , Neovascularization, Physiologic*/drug effects, Animals ; Mice, Inbred C57BL ; Mice ; Leucine/analogs & derivatives ; Leucine/pharmacology ; Sulfonamides/pharmacology ; Aorta/drug effects ; Aorta/metabolism ; Molecular Targeted Therapy ; Angiogenesis ; Morpholines ; Pyrroles

From inflammation to remodelling: A novel BASP1 ⁺ monocyte subset as a catalyst for acute aortic dissection.

Autoren: He W Yu S Li J et al.

Quelle: Journal of advanced research [J Adv Res] 2025 Dec; Vol. 78, pp. 647-666. Date of Electronic Publication: 2025 Mar 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cairo University, production and hosting by Elsevier B. V Country of Publication: Egypt NLM ID: 101546952 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2090-1224 (Electronic) Linking ISSN: 20901224 NLM ISO Abbreviation: J Adv Res Subsets: MEDLINE

MeSH-Schlagworte: Monocytes*/metabolism , Monocytes*/immunology , Aortic Dissection*/pathology , Aortic Dissection*/metabolism , Inflammation*/metabolism , Inflammation*/pathology , Vascular Remodeling* , Membrane Proteins*/metabolism , Nerve Tissue Proteins*/metabolism , Nerve Tissue Proteins*/genetics, Animals ; Humans ; Mice ; Macrophages/metabolism ; Male ; Aorta/pathology ; Aorta/metabolism ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/metabolism ; Disease Models, Animal

External stent ameliorates vein graft remodeling through Ajuba-mediated suppression of Hippo signaling pathway.

Autoren: Yang Y Qian B Zhou D et al.

Quelle: Biomaterials advances [Biomater Adv] 2025 Dec; Vol. 177, pp. 214427. Date of Electronic Publication: 2025 Jul 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE

MeSH-Schlagworte: Stents* , Signal Transduction* , LIM Domain Proteins*/metabolism , Saphenous Vein*/transplantation , Saphenous Vein*/metabolism , Protein Serine-Threonine Kinases*/metabolism , Vascular Remodeling*, Hippo Signaling Pathway ; Humans ; Animals ; Cell Proliferation ; Stress, Mechanical ; Male

H19/miRNA-675 axis: a possible new strategy to alleviate pulmonary vascular remodelling in COPD by Qibai Pingfei Capsule.

Autoren: Xie J Tang S Wu H et al.

Quelle: Fitoterapia [Fitoterapia] 2025 Dec; Vol. 187, pp. 106907. Date of Electronic Publication: 2025 Oct 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/drug therapy , RNA, Long Noncoding*/metabolism , RNA, Long Noncoding*/genetics , Vascular Remodeling*/drug effects , MicroRNAs*/metabolism , MicroRNAs*/genetics , Drugs, Chinese Herbal*/pharmacology, Humans ; Animals ; Male ; Mice ; Lung/drug effects ; Lung/blood supply ; Mice, Inbred C57BL

Turbulence drives arteriovenous remodeling: an experimentally validated multi-scale model of neointimal hyperplasia.

Autoren: Varsanik MA Thaxton C Nguyen D et al.

Quelle: Physics in medicine and biology [Phys Med Biol] 2025 Nov 20; Vol. 70 (23). Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article; Validation Study

Info zur Zeitschrift: Publisher: IOP Publishing Country of Publication: England NLM ID: 0401220 Publication Model: Electronic Cited Medium: Internet ISSN: 1361-6560 (Electronic) Linking ISSN: 00319155 NLM ISO Abbreviation: Phys Med Biol Subsets: MEDLINE

MeSH-Schlagworte: Neointima*/pathology , Neointima*/physiopathology , Vascular Remodeling* , Arteriovenous Fistula*/pathology , Arteriovenous Fistula*/physiopathology, Animals ; Hyperplasia ; Mice ; Hydrodynamics ; Hemodynamics

BMP9 knockout impairs pulmonary vessel muscularisation and confers aberrant tamoxifen sensitivity.

Autoren: Dunmore BJ Moore S Jones RJ et al.

Körperschaften: Dunmore BJ Moore S Jones RJ et al.

Quelle: Angiogenesis [Angiogenesis] 2025 Nov 12; Vol. 29 (1), pp. 5. Date of Electronic Publication: 2025 Nov 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Germany NLM ID: 9814575 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7209 (Electronic) Linking ISSN: 09696970 NLM ISO Abbreviation: Angiogenesis Subsets: MEDLINE

MeSH-Schlagworte: Tamoxifen*/pharmacology , Growth Differentiation Factor 2*/genetics , Growth Differentiation Factor 2*/metabolism , Growth Differentiation Factor 2*/deficiency , Muscle, Smooth, Vascular*/metabolism , Muscle, Smooth, Vascular*/pathology , Muscle, Smooth, Vascular*/drug effects , Pulmonary Artery*/pathology , Pulmonary Artery*/metabolism , Pulmonary Artery*/drug effects , Vascular Remodeling*/drug effects, Animals ; Mice, Knockout ; Mice ; Humans ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology

Acinar-derived VEGF-A orchestrates blood vascular remodeling and preserves microvessels during acute pancreatitis.

Autoren: Aajja E Lefort H Mahibullah S et al.

Quelle: Cell communication and signaling : CCS [Cell Commun Signal] 2025 Nov 11; Vol. 23 (1), pp. 490. Date of Electronic Publication: 2025 Nov 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE

MeSH-Schlagworte: Vascular Endothelial Growth Factor A*/metabolism , Pancreatitis*/pathology , Pancreatitis*/metabolism , Vascular Remodeling* , Acinar Cells*/metabolism , Acinar Cells*/pathology , Microvessels*/pathology , Microvessels*/metabolism, Animals ; Mice ; Acute Disease ; Mice, Inbred C57BL ; Ceruletide ; Male ; Capillary Permeability

Plumbagin improves pulmonary vascular remodeling in PAH via miR-21-5p/MMP/TIMP regulation, with diagnostic implications for cardiac function.

Autoren: Hsieh CC Kuo HF Wang HH et al.

Quelle: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Nov; Vol. 192, pp. 118604. Date of Electronic Publication: 2025 Sep 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH-Schlagworte: MicroRNAs*/genetics , MicroRNAs*/metabolism , Vascular Remodeling*/drug effects , Naphthoquinones*/pharmacology , Naphthoquinones*/therapeutic use , Pulmonary Arterial Hypertension*/drug therapy , Pulmonary Arterial Hypertension*/physiopathology , Matrix Metalloproteinases*/metabolism , Tissue Inhibitor of Metalloproteinases*/metabolism, Animals ; Humans ; Male ; Mice ; Pulmonary Artery/drug effects ; Pulmonary Artery/pathology ; Pulmonary Artery/physiopathology ; Disease Models, Animal ; Bone Morphogenetic Protein Receptors, Type II/metabolism ; Bone Morphogenetic Protein Receptors, Type II/genetics ; Mice, Inbred C57BL ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Monocrotaline ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Tissue Inhibitor of Metalloproteinase-3/metabolism ; Cells, Cultured