Search Results - "VACCINE development"

Innovations and challenges in vaccine development: Lessons from the SARS-CoV-2 pandemic and prospects.

Authors: Mohammed A Ibrahim NA Basher NS

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Dec 15; Vol. 792, pp. 152947. Date of Electronic Publication: 2025 Nov 07.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH Terms: COVID-19*/prevention & control , COVID-19*/epidemiology , COVID-19*/immunology , COVID-19 Vaccines*/immunology , Vaccine Development*/methods , Vaccine Development*/trends , SARS-CoV-2*/immunology , Pandemics*/prevention & control, Humans ; Artificial Intelligence ; Vaccination

Legal questions of AI-generated immunological products for infectious diseases.

Authors: Zumárraga J McConnell MJ López D et al.

Source: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2570962. Date of Electronic Publication: 2025 Oct 15.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

MeSH Terms: Artificial Intelligence*/legislation & jurisprudence , Communicable Diseases*/therapy , Vaccines*/immunology , Vaccine Development*/legislation & jurisprudence , Vaccine Development*/methods, Humans ; Liability, Legal

Adaptive clinical trial designs for rapid vaccine development: Developing country vaccine manufacturers' perspective.

Authors: Mahajan M Martin LB Gaurav K et al.

Source: Vaccine [Vaccine] 2025 Dec 05; Vol. 68, pp. 127890. Date of Electronic Publication: 2025 Nov 01.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE

MeSH Terms: Vaccine Development*/methods , Drug Industry* , Vaccines* , Adaptive Clinical Trials as Topic*/methods , Research Design* , Clinical Trials as Topic*/methods, Humans ; Developing Countries

Virus-like particles: a versatile and effective vaccine platform.

Authors: Bachmann MF van Damme P Lienert F et al.

Source: Expert review of vaccines [Expert Rev Vaccines] 2025 Dec; Vol. 24 (1), pp. 444-456. Date of Electronic Publication: 2025 May 22.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101155475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8395 (Electronic) Linking ISSN: 14760584 NLM ISO Abbreviation: Expert Rev Vaccines Subsets: MEDLINE

MeSH Terms: Vaccines, Virus-Like Particle*/immunology , Vaccines, Virus-Like Particle*/administration & dosage , Vaccines, Virus-Like Particle*/adverse effects , Vaccine Development*/methods , Viral Vaccines*/immunology , Viral Vaccines*/administration & dosage , Viral Vaccines*/adverse effects, Humans ; Animals ; Vaccines, Attenuated/immunology ; Vaccines, Attenuated/administration & dosage

Gaps in vaccine clinical trials in Africa: A mixed scoping review and bibliometric analysis before, during, and post- COVID-19 pandemic.

Authors: Uthman OA Katoto PDMC Anjorin SS et al.

Source: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2481802. Date of Electronic Publication: 2025 Mar 25.

Publication Type: Journal Article; Scoping Review

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

MeSH Terms: COVID-19*/prevention & control , COVID-19*/epidemiology , COVID-19 Vaccines* , Clinical Trials as Topic*/statistics & numerical data , Vaccine Development*, Humans ; Africa/epidemiology ; Bibliometrics ; SARS-CoV-2/immunology ; Pandemics/prevention & control

Applications of artificial intelligence and nanotechnology in vaccine development.

Authors: Bahrami Y Bolideei M Mohammadzadeh S et al.

Source: International journal of pharmaceutics [Int J Pharm] 2025 Nov 10; Vol. 684, pp. 126096. Date of Electronic Publication: 2025 Aug 29.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

MeSH Terms: Artificial Intelligence* , Nanotechnology*/methods , Vaccine Development*/methods , COVID-19 Vaccines*/immunology , COVID-19 Vaccines*/administration & dosage, Humans ; COVID-19/prevention & control ; COVID-19/immunology ; Animals ; Nanoparticles ; SARS-CoV-2/immunology

A high-throughput multi-species platform using Biolayer Interferometry Immunosorbent Assay (BLI-ISA) as an alternative to indirect ELISA for vaccine development.

Authors: Lu T Parvej MS Whittier SK et al.

Source: Journal of immunological methods [J Immunol Methods] 2025 Nov; Vol. 544, pp. 113980. Date of Electronic Publication: 2025 Sep 18.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1305440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7905 (Electronic) Linking ISSN: 00221759 NLM ISO Abbreviation: J Immunol Methods Subsets: MEDLINE

MeSH Terms: Interferometry*/methods , High-Throughput Screening Assays*/methods , Vaccine Development*/methods, Enzyme-Linked Immunosorbent Assay/methods ; Animals ; Humans ; Reproducibility of Results

The Sweet Aspects of Orthoflavivirus Treatment Design and Vaccine Development.

Authors: Alcalá AC Gutiérrez M Ludert JE

Source: Journal of medical virology [J Med Virol] 2025 Oct; Vol. 97 (10), pp. e70637.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE

MeSH Terms: Vaccine Development* , Viral Vaccines*/immunology , Viral Vaccines*/isolation & purification , Antiviral Agents*/therapeutic use , Antiviral Agents*/pharmacology, Humans ; Animals ; Glycoproteins/immunology

An alphavirus vaccine development utilizing RNA replication-defective strategy.

Authors: Zhang Z Huang J Li Z et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2025 Dec 03; Vol. 33 (12), pp. 6282-6297. Date of Electronic Publication: 2025 Sep 02.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

MeSH Terms: Virus Replication*/genetics , Viral Vaccines*/immunology , Viral Vaccines*/genetics , Viral Vaccines*/administration & dosage , Alphavirus*/immunology , Alphavirus*/genetics , Vaccine Development* , Alphavirus Infections*/prevention & control , Alphavirus Infections*/immunology , Alphavirus Infections*/virology , RNA, Viral*/genetics, Animals ; Mice ; Cell Line ; Encephalitis Virus, Venezuelan Equine/genetics ; Encephalitis Virus, Venezuelan Equine/immunology ; Viral Nonstructural Proteins/genetics ; Humans ; Disease Models, Animal ; RNA Replication

Trends and disparities in the research and development of infectious disease vaccines from 2015 to 2025.

Authors: Du M Chen W Li G et al.

Source: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2581440. Date of Electronic Publication: 2025 Nov 06.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

MeSH Terms: Vaccine Development*/trends , Biomedical Research*/trends , Communicable Diseases*, Humans ; COVID-19 Vaccines ; COVID-19/prevention & control ; AIDS Vaccines

Bioprofiling and vaccine development for Zika virus.

Authors: Shi H Feng S Naeem A et al.

Source: Science China. Life sciences [Sci China Life Sci] 2025 Dec; Vol. 68 (12), pp. 3436-3449. Date of Electronic Publication: 2025 Jun 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: Science China Press, co-published with Springer Country of Publication: China NLM ID: 101529880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1869-1889 (Electronic) Linking ISSN: 16747305 NLM ISO Abbreviation: Sci China Life Sci Subsets: MEDLINE

MeSH Terms: Zika Virus Infection*/prevention & control , Zika Virus Infection*/transmission , Zika Virus Infection*/immunology , Zika Virus Infection*/virology , Zika Virus Infection*/epidemiology , Zika Virus*/immunology , Zika Virus*/physiology , Viral Vaccines*/immunology , Vaccine Development*, Humans ; Animals ; Guillain-Barre Syndrome/virology ; Guillain-Barre Syndrome/prevention & control ; Antibody-Dependent Enhancement

Public sector innovation and the constraints of 'platform thinking': An account of Johnson & Johnson's adenoviral vector vaccines.

Authors: Sariahmed K Graham JE Herder M et al.

Source: Social science & medicine (1982) [Soc Sci Med] 2025 Dec; Vol. 387, pp. 118687. Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: Pergamon Country of Publication: England NLM ID: 8303205 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5347 (Electronic) Linking ISSN: 02779536 NLM ISO Abbreviation: Soc Sci Med Subsets: MEDLINE

MeSH Terms: COVID-19 Vaccines*/economics , COVID-19*/prevention & control , Public Sector* , Vaccine Development*/methods, Humans ; Adenoviridae ; Qualitative Research ; SARS-CoV-2 ; Genetic Vectors

Clinical and Quantitative Pharmacology Considerations of mRNA Therapeutics and Vaccine Development: Bridging Translational and Platform Gaps for Enhanced Decision Making.

Authors: Van LM Chen N Miyazawa K et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Dec; Vol. 118 (6), pp. 1297-1312. Date of Electronic Publication: 2025 Oct 14.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

MeSH Terms: RNA, Messenger*/administration & dosage , RNA, Messenger*/pharmacokinetics , RNA, Messenger*/therapeutic use , Vaccine Development*/methods , Translational Research, Biomedical*/methods, Humans ; Pharmacology, Clinical/methods ; Nanoparticles ; Animals ; Decision Making ; Machine Learning ; Drug Development/methods ; Lipids ; Drug Discovery/methods ; Liposomes

Development of the coronavirus reverse genetic system: Core technology for pathogenesis mechanisms research and vaccine/drug development.

Authors: Zhang Y Hou R Wei Z et al.

Source: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2525930. Date of Electronic Publication: 2025 Jun 28.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH Terms: Reverse Genetics*/methods , Vaccine Development* , Coronavirus*/genetics , Coronavirus*/pathogenicity, Humans ; Animals ; Drug Development ; SARS-CoV-2/genetics ; SARS-CoV-2/pathogenicity ; Viral Vaccines/immunology ; Antiviral Agents/pharmacology ; COVID-19 Vaccines

Enterobactin: A key player in bacterial iron acquisition and virulence and its implications for vaccine development and antimicrobial strategies.

Authors: Amiri M Golchin M Jamshidian Mojaver M et al.

Source: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2563018. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH Terms: Enterobactin*/metabolism , Enterobactin*/biosynthesis , Iron*/metabolism , Vaccine Development*, Humans ; Virulence ; Animals ; Siderophores/metabolism ; Escherichia coli/pathogenicity ; Escherichia coli/metabolism ; Anti-Bacterial Agents/pharmacology

Advances in vaccine adjuvant development and future perspectives.

Authors: Sinani G Şenel S

Source: Drug delivery [Drug Deliv] 2025 Dec; Vol. 32 (1), pp. 2517137. Date of Electronic Publication: 2025 Jun 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9417471 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0464 (Electronic) Linking ISSN: 10717544 NLM ISO Abbreviation: Drug Deliv Subsets: MEDLINE

MeSH Terms: Adjuvants, Vaccine*/administration & dosage , Adjuvants, Vaccine*/pharmacology , Vaccines*/immunology , Vaccines*/administration & dosage , Adjuvants, Immunologic* , Vaccine Development*/methods, Humans ; Animals ; Systems Biology ; Artificial Intelligence

Breaking barriers in CRC immunotherapy: Cutting-edge advances in personalized peptide vaccine development.

Authors: Huang H Ren J Jiang D et al.

Source: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2025 Dec; Vol. 216, pp. 104967. Date of Electronic Publication: 2025 Sep 23.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Netherlands NLM ID: 8916049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0461 (Electronic) Linking ISSN: 10408428 NLM ISO Abbreviation: Crit Rev Oncol Hematol Subsets: MEDLINE

MeSH Terms: Colorectal Neoplasms*/therapy , Colorectal Neoplasms*/immunology , Cancer Vaccines*/therapeutic use , Cancer Vaccines*/immunology , Precision Medicine*/methods , Immunotherapy*/methods , Vaccines, Subunit*/immunology , Vaccines, Subunit*/therapeutic use , Vaccine Development*/methods, Humans ; Tumor Microenvironment/immunology ; Animals ; Antigens, Neoplasm/immunology

A One Health approach to bovine coronavirus vaccine development, using LSDV as a live virus vector.

Authors: Chineka N Whittle L Douglass N et al.

Source: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2480891. Date of Electronic Publication: 2025 Apr 11.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

MeSH Terms: Viral Vaccines*/immunology , Viral Vaccines*/genetics , Viral Vaccines*/administration & dosage , Vaccine Development*/methods , Genetic Vectors* , Lumpy skin disease virus*/genetics , Lumpy skin disease virus*/immunology , Coronavirus, Bovine*/immunology , Coronavirus, Bovine*/genetics , Coronavirus Infections*/prevention & control , Coronavirus Infections*/veterinary, Animals ; Cattle ; Vaccines, Attenuated/immunology ; Vaccines, Attenuated/genetics ; Vaccines, Attenuated/administration & dosage ; Spike Glycoprotein, Coronavirus/immunology ; Spike Glycoprotein, Coronavirus/genetics ; Mice ; Antibodies, Viral/blood ; Vaccines, Synthetic/immunology ; Vaccines, Synthetic/genetics ; Vaccines, Synthetic/administration & dosage ; One Health ; Mice, Inbred BALB C ; Humans ; Female ; Coronavirus Nucleocapsid Proteins/immunology ; Lumpy Skin Disease/prevention & control

Developing the next-generation of adenoviral vector vaccines.

Authors: Sampson AT Hlaváč M Gillman ACT et al.

Source: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2514356. Date of Electronic Publication: 2025 Jul 01.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

MeSH Terms: Genetic Vectors*/immunology , Genetic Vectors*/genetics , COVID-19 Vaccines*/immunology , COVID-19 Vaccines*/genetics , COVID-19 Vaccines*/adverse effects , COVID-19 Vaccines*/administration & dosage , COVID-19*/prevention & control , COVID-19*/immunology , Adenoviridae*/genetics , Adenoviridae*/immunology , Vaccine Development*/methods, Humans ; SARS-CoV-2/immunology ; Immunogenicity, Vaccine

Age-related changes in the immune system and challenges for the development of age-specific vaccines.

Authors: Doherty TM Weinberger B Didierlaurent A et al.

Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2477300. Date of Electronic Publication: 2025 Mar 20.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH Terms: Immunosenescence*/immunology , Aging*/immunology , COVID-19 Vaccines*/immunology , COVID-19*/prevention & control , COVID-19*/immunology , Vaccine Development*/methods , Immune System*, Humans ; Aged ; Immunity, Innate ; Immunogenicity, Vaccine/immunology ; SARS-CoV-2/immunology ; Influenza Vaccines/immunology ; Adjuvants, Immunologic ; Age Factors ; Vaccination/methods