Search Results - "UREMIA"

Uremic serum exposure leads to differential phenotypic switch in porcine arterial and venous smooth muscle cells.

Authors: Su H Uriyanghai U Wai C et al.

Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2025 Dec 01; Vol. 329 (6), pp. F809-F819. Date of Electronic Publication: 2025 Oct 25.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE

MeSH Terms: Uremia*/blood , Uremia*/pathology , Myocytes, Smooth Muscle*/metabolism , Myocytes, Smooth Muscle*/pathology , Muscle, Smooth, Vascular*/metabolism , Muscle, Smooth, Vascular*/pathology , Veins*/metabolism , Veins*/pathology, Animals ; Phenotype ; Cell Proliferation ; Cell Movement ; Cells, Cultured ; Kruppel-Like Factor 4 ; Swine

Bidirectional Mendelian Randomization analysis of iron status and uremia: no evidence of a causal relationship.

Authors: Chen J Zhao H He Y et al.

Source: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2488138. Date of Electronic Publication: 2025 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH Terms: Uremia*/genetics , Uremia*/blood , Iron*/blood, Humans ; Mendelian Randomization Analysis ; Genome-Wide Association Study ; Transferrin/metabolism ; Ferritins/blood

Uremic toxins removal and iron status: a medium-term comparison between 4 dialysis techniques (EMPIRE study).

Authors: Napoli M Alfano G Scrivo A et al.

Source: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2497491. Date of Electronic Publication: 2025 May 05.

Publication Type: Journal Article; Observational Study; Comparative Study

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH Terms: Renal Dialysis*/methods , Iron*/blood , Kidney Failure, Chronic*/therapy , Kidney Failure, Chronic*/blood , Hemodiafiltration*/methods , Uremic Toxins*/blood , Uremic Toxins*/isolation & purification , Uremia*/therapy , Uremia*/blood, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Aged ; Adult ; Urea/blood ; Transferrin/analysis

Qualitative study on the sense of meaning in life in uremic patients undergoing initial hemodialysis.

Authors: Li C Shan Y Yan X et al.

Source: International journal of qualitative studies on health and well-being [Int J Qual Stud Health Well-being] 2025 Dec; Vol. 20 (1), pp. 2545262. Date of Electronic Publication: 2025 Aug 19.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101256506 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-2631 (Electronic) Linking ISSN: 17482623 NLM ISO Abbreviation: Int J Qual Stud Health Well-being Subsets: MEDLINE

MeSH Terms: Renal Dialysis*/psychology , Adaptation, Psychological* , Uremia*/therapy , Uremia*/psychology , Quality of Life*/psychology, Humans ; Qualitative Research ; Female ; Male ; Middle Aged ; Aged ; Adult ; Emotions

Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis.

Authors: Feng J Chen R Chen Y et al.

Source: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2538268. Date of Electronic Publication: 2025 Aug 13.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH Terms: Autophagy*/genetics , Uremia*/complications , Atherosclerosis*/etiology , Atherosclerosis*/pathology , Atherosclerosis*/metabolism , Atherosclerosis*/genetics , Muscle, Smooth, Vascular*/pathology , Muscle, Smooth, Vascular*/metabolism , Muscle, Smooth, Vascular*/cytology , Renal Insufficiency, Chronic*/complications , Myocytes, Smooth Muscle*/metabolism , Myocytes, Smooth Muscle*/pathology, Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; Cells, Cultured ; Phosphorylation ; Protein Interaction Maps ; Male

Development of a convenient and rapid screening zebrafish model to investigate lethal effects and immunocompromised states of uremic toxins.

Authors: Jo P Zhang R Zhang Y et al.

Source: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2514183. Date of Electronic Publication: 2025 Jun 08.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH Terms: Zebrafish* , Uremia*/immunology , Uremia*/mortality , Disease Models, Animal* , Immunocompromised Host* , Uremic Toxins*/toxicity , Dialysis Solutions*/toxicity, Animals ; Animals, Genetically Modified ; Macrophages/immunology ; Macrophages/drug effects ; Peritoneal Dialysis ; Larva

Prevalence of uremic neuropathy and the effect of dialysis in children with end-stage renal disease: A cohort study.

Authors: Yahyaoui A Gammoudi N Nouir S et al.

Source: PloS one [PLoS One] 2025 Nov 25; Vol. 20 (11), pp. e0337696. Date of Electronic Publication: 2025 Nov 25 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Kidney Failure, Chronic*/therapy , Kidney Failure, Chronic*/complications , Renal Dialysis*/adverse effects , Uremia*/complications , Uremia*/epidemiology , Uremia*/therapy , Nervous System Diseases*/epidemiology , Nervous System Diseases*/etiology, Humans ; Child ; Male ; Female ; Prevalence ; Adolescent ; Prospective Studies ; Quality of Life ; Tunisia/epidemiology ; Cohort Studies ; Child, Preschool

Astrocytic LCN2 drives uremic pruritus and morphine-induced pruritus via the GRP/GRPR pathway.

Authors: Li H Gao W Mu X et al.

Source: Clinical and experimental nephrology [Clin Exp Nephrol] 2025 Nov; Vol. 29 (11), pp. 1546-1557. Date of Electronic Publication: 2025 May 18.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Japan NLM ID: 9709923 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7799 (Electronic) Linking ISSN: 13421751 NLM ISO Abbreviation: Clin Exp Nephrol Subsets: MEDLINE

MeSH Terms: Pruritus*/chemically induced , Pruritus*/metabolism , Pruritus*/etiology , Lipocalin-2*/metabolism , Lipocalin-2*/genetics , Astrocytes*/metabolism , Uremia*/metabolism , Uremia*/complications, Animals ; Morphine ; Humans ; Mice, Knockout ; Signal Transduction ; Mice ; Male ; Disease Models, Animal ; Female ; Middle Aged ; Mice, Inbred C57BL ; Renal Insufficiency, Chronic/complications

High-flux hemodialysis with polymethylmethacrylate membranes reduces soluble CD40L, a mediator of cardiovascular disease in uremia.

Authors: Marengo M Migliori M Merlotti G et al.

Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2025 Oct 30; Vol. 40 (11), pp. 2131-2142.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE

MeSH Terms: Renal Dialysis*/adverse effects , Renal Dialysis*/methods , CD40 Ligand*/blood , CD40 Ligand*/metabolism , Uremia*/therapy , Uremia*/complications , Uremia*/blood , Polymethyl Methacrylate* , Cardiovascular Diseases*/etiology , Cardiovascular Diseases*/blood , Cardiovascular Diseases*/prevention & control , Membranes, Artificial* , Kidney Failure, Chronic*/therapy , Kidney Failure, Chronic*/complications, Humans ; Male ; Female ; Middle Aged ; Aged ; Cross-Over Studies ; Prognosis ; Follow-Up Studies ; Polymers

Leptin and Adiponectin as Uremic Adipokines: Associations with Survival in a Prospective Hemodialysis Cohort.

Authors: Bui TV You AS Kalantar SS et al.

Source: Toxins [Toxins (Basel)] 2025 Oct 25; Vol. 17 (11). Date of Electronic Publication: 2025 Oct 25.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651 (Electronic) Linking ISSN: 20726651 NLM ISO Abbreviation: Toxins (Basel) Subsets: MEDLINE

MeSH Terms: Leptin*/blood , Adiponectin*/blood , Renal Dialysis* , Uremia*/blood , Uremia*/mortality , Renal Insufficiency, Chronic*/blood , Renal Insufficiency, Chronic*/therapy , Renal Insufficiency, Chronic*/mortality, Humans ; Female ; Male ; Middle Aged ; Prospective Studies ; Aged ; Biomarkers/blood

Role of Staphylococcus aureus Nasal Carriage in Uremic Pruritus and Infection in Hemodialysis Patients.

Authors: Ko MJ Chiang J Liao CH et al.

Source: International journal of dermatology [Int J Dermatol] 2025 Oct; Vol. 64 (10), pp. 1833-1838. Date of Electronic Publication: 2025 Jun 17.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Science Country of Publication: England NLM ID: 0243704 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-4632 (Electronic) Linking ISSN: 00119059 NLM ISO Abbreviation: Int J Dermatol Subsets: MEDLINE

MeSH Terms: Pruritus*/epidemiology , Pruritus*/etiology , Pruritus*/microbiology , Renal Dialysis*/adverse effects , Staphylococcus aureus*/isolation & purification , Staphylococcal Infections*/epidemiology , Staphylococcal Infections*/microbiology , Staphylococcal Infections*/diagnosis , Carrier State*/microbiology , Carrier State*/epidemiology , Uremia*/therapy , Uremia*/complications, Humans ; Male ; Female ; Middle Aged ; Prospective Studies ; Aged ; Prevalence ; Taiwan/epidemiology ; Severity of Illness Index ; Adult

Acute Hemorrhagic Rectal Ulcer in a Uremic Patient: A Case Report and Literature Review.

Authors: Liu D Han X Li M et al.

Source: Hemodialysis international. International Symposium on Home Hemodialysis [Hemodial Int] 2025 Oct; Vol. 29 (4), pp. 730-736. Date of Electronic Publication: 2025 Jun 12.

Publication Type: Journal Article; Case Reports; Review

Journal Info: Publisher: Blackwell Pub Country of Publication: Canada NLM ID: 101093910 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-4758 (Electronic) Linking ISSN: 14927535 NLM ISO Abbreviation: Hemodial Int Subsets: MEDLINE

MeSH Terms: Uremia*/complications , Uremia*/therapy , Renal Dialysis*/adverse effects , Renal Dialysis*/methods , Gastrointestinal Hemorrhage*/etiology , Gastrointestinal Hemorrhage*/therapy , Ulcer*/complications , Ulcer*/etiology , Ulcer*/therapy , Rectal Diseases*/etiology , Kidney Failure, Chronic*/therapy , Kidney Failure, Chronic*/complications, Humans ; Female ; Aged ; Acute Disease

A specifically designed multi-biotic reduces uremic toxin generation and improves kidney function.

Authors: Beau A Natividad J Benoit B et al.

Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2531202. Date of Electronic Publication: 2025 Jul 12.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

MeSH Terms: Uremic Toxins*/metabolism , Renal Insufficiency, Chronic*/microbiology , Renal Insufficiency, Chronic*/therapy , Probiotics*/administration & dosage , Gastrointestinal Microbiome* , Kidney*/physiology , Uremia*, Humans ; Animals ; Feces/microbiology ; Feces/chemistry ; Male ; Cresols/metabolism ; Prebiotics/administration & dosage ; Female ; Middle Aged ; Lactobacillus/metabolism ; Lactobacillus/growth & development ; Cellobiose/metabolism ; Rats ; Indican ; Bacteria/metabolism ; Bacteria/genetics ; Bacteria/classification ; Disease Models, Animal

Lactoferrin attenuates renal fibrosis and uremic sarcopenia in a mouse model of adenine-induced chronic kidney disease.

Authors: Iwamoto Y Yamakoshi S Sekimoto A et al.

Source: The Journal of nutritional biochemistry [J Nutr Biochem] 2025 Dec; Vol. 146, pp. 110039. Date of Electronic Publication: 2025 Jul 24.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE

MeSH Terms: Lactoferrin*/pharmacology , Lactoferrin*/therapeutic use , Sarcopenia*/drug therapy , Sarcopenia*/etiology , Sarcopenia*/prevention & control , Renal Insufficiency, Chronic*/chemically induced , Renal Insufficiency, Chronic*/drug therapy , Renal Insufficiency, Chronic*/pathology , Renal Insufficiency, Chronic*/complications , Kidney*/pathology , Kidney*/drug effects , Uremia*/drug therapy, Animals ; Adenine/toxicity ; Disease Models, Animal ; Mice ; Male ; Mice, Inbred C57BL ; Fibrosis ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/pathology ; Gastrointestinal Microbiome/drug effects

Comprehensive Bibliometric Analysis of Uremic Toxin Research.

Authors: Hardjo M Wakamatsu T Watanabe K et al.

Source: Toxins [Toxins (Basel)] 2025 Oct 30; Vol. 17 (11). Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651 (Electronic) Linking ISSN: 20726651 NLM ISO Abbreviation: Toxins (Basel) Subsets: MEDLINE

MeSH Terms: Bibliometrics* , Uremic Toxins*/metabolism , Renal Insufficiency, Chronic*/metabolism , Uremia*, Humans ; Gastrointestinal Microbiome ; Animals ; Biomedical Research

Hemocompatibility of cyclodextrin-coated magnetic nanoparticles under uremic conditions.

Authors: Ghaffari Sharaf M Li S Rowe EM et al.

Source: Carbohydrate polymers [Carbohydr Polym] 2025 Oct 15; Vol. 366, pp. 123836. Date of Electronic Publication: 2025 Jun 02.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1344 (Electronic) Linking ISSN: 01448617 NLM ISO Abbreviation: Carbohydr Polym Subsets: MEDLINE

MeSH Terms: Uremia*/blood , Cyclodextrins*/chemistry , Magnetite Nanoparticles*/chemistry , Coated Materials, Biocompatible*/chemistry, Humans ; Adsorption ; Renal Dialysis ; Blood Proteins/chemistry

Autologous platelet-rich plasma therapy for skin ulceration due to calcific uremic arteriopathy: a case report and review of the literature.

Authors: Liu H Xue J Yu S et al.

Source: International urology and nephrology [Int Urol Nephrol] 2025 Oct; Vol. 57 (10), pp. 3319-3325. Date of Electronic Publication: 2025 Apr 12.

Publication Type: Journal Article; Case Reports; Review

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0262521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2584 (Electronic) Linking ISSN: 03011623 NLM ISO Abbreviation: Int Urol Nephrol Subsets: MEDLINE

MeSH Terms: Platelet-Rich Plasma* , Skin Ulcer*/therapy , Skin Ulcer*/etiology , Kidney Failure, Chronic*/complications , Kidney Failure, Chronic*/therapy , Vascular Calcification*/complications , Vascular Calcification*/therapy , Vascular Calcification*/etiology , Uremia*/complications , Calciphylaxis*/complications, Humans ; Male ; Middle Aged ; Wound Healing ; Renal Dialysis/adverse effects ; Aged

Serum sortilin as a potential diagnostic and therapeutic target for cardiovascular calcification in uremic patients: A single-center prospective and observational study.

Authors: Zhang Y Chen J Di Y et al.

Source: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2026 Jan 01; Vol. 578, pp. 120554. Date of Electronic Publication: 2025 Aug 24.

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1302422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3492 (Electronic) Linking ISSN: 00098981 NLM ISO Abbreviation: Clin Chim Acta Subsets: MEDLINE

MeSH Terms: Adaptor Proteins, Vesicular Transport*/blood , Uremia*/blood , Uremia*/complications , Uremia*/diagnosis , Cardiovascular Diseases*/blood , Cardiovascular Diseases*/diagnosis , Cardiovascular Diseases*/complications , Vascular Calcification*/blood , Vascular Calcification*/diagnosis, Humans ; Male ; Female ; Middle Aged ; Prospective Studies ; Cross-Sectional Studies ; Aged ; Biomarkers/blood

The role of uremic toxin indoxyl sulfate in the pathophysiology of aortic valve stenosis.

Authors: Düsing P Göbel I Ackerschott A et al.

Source: Cardiovascular research [Cardiovasc Res] 2025 Sep 29; Vol. 121 (11), pp. 1734-1749.

Publication Type: Journal Article

Journal Info: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

MeSH Terms: Indican*/toxicity , Indican*/metabolism , Aortic Valve*/metabolism , Aortic Valve*/pathology , Aortic Valve*/physiopathology , Aortic Valve*/drug effects , Aortic Valve Stenosis*/metabolism , Aortic Valve Stenosis*/pathology , Aortic Valve Stenosis*/physiopathology , Aortic Valve Stenosis*/genetics , Aortic Valve Stenosis*/etiology , Aortic Valve Stenosis*/chemically induced , Renal Insufficiency, Chronic*/metabolism , Renal Insufficiency, Chronic*/complications , Renal Insufficiency, Chronic*/chemically induced , Calcinosis*/metabolism , Calcinosis*/pathology , Calcinosis*/physiopathology , Calcinosis*/genetics , Uremia*/metabolism , Uremia*/complications , Uremia*/chemically induced , Uremic Toxins*/metabolism , Uremic Toxins*/toxicity, Animals ; Humans ; Mice, Inbred C57BL ; Disease Models, Animal ; Signal Transduction ; Interleukin-6/metabolism ; Interleukin-6/genetics ; Cells, Cultured ; Male ; NF-kappa B/metabolism ; Organic Anion Transporters/metabolism ; Organic Anion Transporters/genetics ; Fibrosis ; Macrophages/metabolism ; Macrophages/pathology ; Adenine

SCR Disease Name: Aortic Valve, Calcification of

Case Report: Psychogenic purpura in a uremic patient on peritoneal dialysis.

Authors: Zhang L Zhang H Zhao Y et al.

Source: Frontiers in immunology [Front Immunol] 2025 Sep 12; Vol. 16, pp. 1625126. Date of Electronic Publication: 2025 Sep 12 (Print Publication: 2025).

Publication Type: Case Reports; Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Purpura*/diagnosis , Purpura*/psychology , Purpura*/etiology , Purpura*/therapy , Uremia*/therapy , Uremia*/psychology , Uremia*/complications , Peritoneal Dialysis*, Humans ; Female ; Aged, 80 and over