Výsledky vyhľadávania - "UPR(mt)"

Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

Autori: Kuzuoglu-Ozturk, Duygu Hu, Zhiqiang Rama, Martina a ďalší

Zdroj: Cell Reports. 35(13)

Predmety: Biochemistry and Cell Biology, Genetics, Biological Sciences, Cancer, 1.1 Normal biological development and functioning, Aetiology, Underpinning research, 2.1 Biological and endogenous factors, Generic health relevance, 5' Untranslated Regions, Animals, Apoptosis, Autophagy, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, CRISPR-Cas Systems, Cell Line, Tumor, Cell Movement, Cell Proliferation, Eukaryotic Initiation Factor-4E, Exons, Genetic Testing, Genome, Human, Humans, Male, Metalloendopeptidases, Mice, Mitochondria, Mitochondrial Proteins, Neoplasms, Peptide Hydrolases, Protein Biosynthesis, Signal Transduction, Stress, Physiological, bcl-X Protein, Bcl-xL, CRISPRi, EJC, Tfeb, UPR(mt)-like stress response, autophagy, cancer, eIF4E, mitochondria, translation control, Pmpcb, mitochondrial UPR, Medical Physiology, Biological sciences

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/1nt8k8xv
https://escholarship.org/content/qt1nt8k8xv/qt1nt8k8xv.pdf

Immp2l Deficiency Induced Granulosa Cell Senescence Through STAT1/ATF4 Mediated UPRmt and STAT1/(ATF4)/HIF1α/BNIP3 Mediated Mitophagy: Prevented by Enocyanin

Autori: Xiaoya Qu Pengge Pan Sinan Cao a ďalší

Zdroj: International Journal of Molecular Sciences ; Volume 25 ; Issue 20 ; Pages: 11122

Predmety: cell senescence, STAT1, UPR mt, mitophagy, enocyanin, HIF1α/BNIP3 pathway

Geografické téma: agris

Popis súboru: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms252011122

Dostupnosť: https://doi.org/10.3390/ijms252011122

Heat Shock Factor HSFA6b Mediates Mitochondrial Unfolded Protein Response in Arabidopsis thaliana

Autori: Guolong Yu Zhuoran Huang Chaocheng Guo a ďalší

Zdroj: Plants ; Volume 13 ; Issue 22 ; Pages: 3116

Predmety: mitochondria, mitochondrial proteotoxic stress, mitochondrial unfolded protein response UPR mt, heat shock factor, heat shock protein

Geografické téma: agris

Popis súboru: application/pdf

Relation: Plant Molecular Biology; https://dx.doi.org/10.3390/plants13223116

Dostupnosť: https://doi.org/10.3390/plants13223116

Use of Caenorhabditis elegans to Unravel the Tripartite Interaction of Kynurenine Pathway, UPRmt and Microbiome in Parkinson’s Disease

Autori: Charles Viau Alyssa Nouar Jianguo Xia

Zdroj: Biomolecules ; Volume 14 ; Issue 11 ; Pages: 1370

Predmety: C. elegans, microbiome, UPR mt, kynurenine, Parkinson’s disease

Geografické téma: agris

Popis súboru: application/pdf

Relation: Molecular Medicine; https://dx.doi.org/10.3390/biom14111370

Dostupnosť: https://doi.org/10.3390/biom14111370

PKR Mediates the Mitochondrial Unfolded Protein Response through Double-Stranded RNA Accumulation under Mitochondrial Stress

Autori: Fedho Kusuma Soyoung Park Kim Anh Nguyen a ďalší

Zdroj: International Journal of Molecular Sciences, Vol 25, Iss 14, p 7738 (2024)

Predmety: UPR MT, PKR, mitochondrial dsRNAs, integrated stress response, mitochondrial stress, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/14/7738; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/82bb996620c4488ebdab6d7daceb2a31

Dostupnosť: https://doi.org/10.3390/ijms25147738
https://doaj.org/article/82bb996620c4488ebdab6d7daceb2a31

The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling

Autori: Zhang, Qian Wu, Xueying Chen, Peng a ďalší

Zdroj: Cell. 174(4)

Predmety: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Neurosciences, 2.1 Biological and endogenous factors, Aetiology, Animals, Animals, Genetically Modified, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Carrier Proteins, Glycoproteins, Intracellular Signaling Peptides and Proteins, Mitochondria, Neurons, Polyubiquitin, Unfolded Protein Response, Vesicular Transport Proteins, Wnt Proteins, EGL-20, UPR(mt), VPS-35, Wnt signaling, mitochondrial unfolded protein response, mitokine, retromer complex, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/7q46n874
https://escholarship.org/content/qt7q46n874/qt7q46n874.pdf

Trends in mitochondrial unfolded protein response research from 2004 to 2022: A bibliometric analysis

Autori: Zelin Ye Ruoning Chai Yujie Luan a ďalší

Zdroj: Front Cell Dev Biol
Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Predmety: Cell and Developmental Biology, QH301-705.5, mitochondrial unfolded protein response, VOSviewer, bibliometrix, UPR mt, Citespace, Biology (General), bibliometrics analysis

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37035249
https://doaj.org/article/f30d3e7e719a4ccea08a30294971d0f5

The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response

Autori: Chamseddine, Douja Mahmud, Siraje A. Westfall, Aundrea K. a ďalší

Zdroj: Cell Reports

Predmety: Atf5, CP: Metabolism, CP: Molecular biology, UPR(mt), cholecystokinin, colitis, epithelial barrier, host-pathogen interaction, hyperglycemia, leptin, mitochondria, satiety, Animals, Caenorhabditis elegans / metabolism, Caenorhabditis elegans Proteins / genetics, Caenorhabditis elegans Proteins / metabolism, Satiety Response, Mitochondria / metabolism, Unfolded Protein Response, Mammals / metabolism

Popis súboru: application/pdf

Relation: https://doi.org/10.1016/j.celrep.2022.111789; Chamseddine, D., Mahmud, S. A., Westfall, A. K., Castoe, T. A., Berg, R. E., & Pellegrino, M. W. (2022). The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response. Cell reports, 41(11), 111789. https://doi.org/10.1016/j.celrep.2022.111789; https://hdl.handle.net/20.500.12503/31998; 41; 11

Dostupnosť: https://hdl.handle.net/20.500.12503/31998

Wars1 downregulation in hepatocytes induces mitochondrial stress and disrupts metabolic homeostasis

Autori: Pontanari, Francesca Demagny, Hadrien Faure, Adrien a ďalší

Predmety: Hepatocytes, ISR, MSR, SLC25A47, Translation, UPR mt, WARS1

Relation: Metabolism: clinical and experimental; #PLACEHOLDER_PARENT_METADATA_VALUE#; KFS-4226-08-2017,KLS 5379-08-2021,KLS-4226-08-2017; 846001; ERC-AdG-787702; 2017K1A1A2013124; 202302,SNSF 310030_212769,SNSF 31003A_179435; https://infoscience.epfl.ch/handle/20.500.14299/244252

Dostupnosť: https://doi.org/10.1016/j.metabol.2024.156061
https://infoscience.epfl.ch/handle/20.500.14299/244252
https://hdl.handle.net/20.500.14299/244252

Honokiol Antagonizes Cadmium-Induced Nephrotoxicity in Quail by Alleviating Autophagy Dysfunction, Apoptosis and Mitochondrial UPR Inhibition with Its Antioxidant Properties

Autori: Kanglei Zhang Wenxuan Dong Jiahui Li a ďalší

Zdroj: Life, Vol 12, Iss 1574, p 1574 (2022)

Predmety: Honokiol, cadmium, kidney, autophagy, apoptosis, UPR mt, Science

Relation: https://www.mdpi.com/2075-1729/12/10/1574; https://doaj.org/toc/2075-1729; https://doaj.org/article/8d172f64d9ef474badd72438d9af516b

Dostupnosť: https://doi.org/10.3390/life12101574
https://doaj.org/article/8d172f64d9ef474badd72438d9af516b

Mitochondrial Unfolded Protein Responses in White Adipose Tissue: Lipoatrophy, Whole-Body Metabolism and Lifespan

Autori: Masaki Kobayashi Yuichiro Nezu Ryoma Tagawa a ďalší

Zdroj: International Journal of Molecular Sciences, Vol 22, Iss 2854, p 2854 (2021)

Predmety: mitochondrial unfolded protein response (UPR mt ), mitokine, white adipose tissue (WAT), lipoatrophy, mitohormesis, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/22/6/2854; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/cc67d3bcfbf248ffb9af1845176646a6

Dostupnosť: https://doi.org/10.3390/ijms22062854
https://doaj.org/article/cc67d3bcfbf248ffb9af1845176646a6

Mitochondrial dysfunction in cancer: Potential roles of ATF5 and the mitochondrial UPR

Autori: Pan Deng Cole M. Haynes Department of Molecular, Cell and Cancer Biology

Prispievatelia: Pan Deng Cole M. Haynes Department of Molecular, Cell and Cancer Biology

Zdroj: Seminars in Cancer Biology. 47:43-49

Predmety: 0301 basic medicine, 0303 health sciences, Cell Biology, Biochemistry, 7. Clean energy, Activating Transcription Factors, Mitochondria, 3. Good health, Cellular and Molecular Physiology, Gene Expression Regulation, Neoplastic, 03 medical and health sciences, Stress, Physiological, Neoplasms, UPR(mt), Unfolded Protein Response, Animals, Humans, ATF5, Molecular Biology, Cancer, Signal Transduction

Prístupová URL adresa: https://europepmc.org/articles/pmc5681445?pdf=render
https://pubmed.ncbi.nlm.nih.gov/28499833
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681445/
https://www.sciencedirect.com/science/article/pii/S1044579X17301256
https://core.ac.uk/display/129346617
http://europepmc.org/articles/PMC5681445
https://escholarship.umassmed.edu/metnet_pubs/115/

Mitochondria and mitochondria-induced signalling molecules as longevity determinants

Autori: Rose, G SANTORO, AURELIA SALVIOLI, STEFANO

Zdroj: Mechanisms of Ageing and Development. 165:115-128

Predmety: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Longevity, Animals, Humans, Human longevity, Mito-nuclear communication, Mitochondria, Mitochondrial epigenetics, Mitochondrial uncoupling, Mitokines, UPR(mt), Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/27964991
https://pubmed.ncbi.nlm.nih.gov/27964991/
https://www.sciencedirect.com/science/article/abs/pii/S0047637416301737
https://europepmc.org/abstract/MED/27964991
https://www.ncbi.nlm.nih.gov/pubmed/27964991

Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes

Autori: Vasquez-Rifo, Alejandro Ricci, Emiliano P. Ambros, Victor a ďalší

Prispievatelia: Vasquez-Rifo, Alejandro Ricci, Emiliano P. Ambros, Victor a ďalší

Zdroj: ISSN: 1544-9173.

Predmety: ER, endoplasmic reticulum GPCR, G protein-coupled receptor H69, helix 69 H79, helix 79 IP, immunoprecipitation LB, Lysogeny Broth lf, loss of function nt, nucleotides PAGE, polyacrylamide gel electrophoresis QS, quorum sensing RNAi, RNA-mediated interference RPM, reads per million rRNA, ribosomal RNA SK, slow killing ts, temperature sensitive UPR ER, unfolded protein response of the endoplasmic reticulum UPR mt, mitochondrial unfolded protein response YA, young adults, endoplasmic reticulum, GPCR, G protein-coupled receptor, H69, helix 69, H79, helix 79, IP, immunoprecipitation, LB, Lysogeny Broth

Dostupnosť: https://hal.science/hal-04892152
https://hal.science/hal-04892152v1/document
https://hal.science/hal-04892152v1/file/file-2.pdf
https://doi.org/10.1371/journal.pbio.3000969

Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR

Autori: Bing Tan Amélie Jaulin Caroline Bund a ďalší

Zdroj: Cancers, Vol 12, Iss 2357, p 2357 (2020)

Predmety: Warburg effect, breast cancer, UPR ER, UPR mt, metabolomics, metabolic flexibility, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://www.mdpi.com/2072-6694/12/9/2357; https://doaj.org/toc/2072-6694; https://doaj.org/article/663655c675204e01b149980592b25fe4

Dostupnosť: https://doi.org/10.3390/cancers12092357
https://doaj.org/article/663655c675204e01b149980592b25fe4

Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans

Autori: Hernando Rodríguez, Blanca Erinjeri, Annmary Paul Rodríguez Palero, María Jesús a ďalší

Prispievatelia: Hernando Rodríguez, Blanca Erinjeri, Annmary Paul Rodríguez Palero, María Jesús a ďalší

Predmety: C. elegans, Essential genes, High-content, High-throughput, Image analysis, Mitochondria, Prohibitins, Screens, UPR mt, Worm sorting

Relation: BMC Biology, 16 (1), 36-.; ERC-2011-StG-281691; BFU2012–35509; http://dx.doi.org/10.1186/s12915-018-0496-5; https://idus.us.es/handle//11441/87298

Dostupnosť: https://idus.us.es/handle//11441/87298

Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt

Autori: Rolland, SG Schneid, S Schwarz, M a ďalší

Zdroj: Cell Reports , 28 (7) 1659-1669.e5. (2019)

Predmety: ATFS-1, C. elegans, GCN-2, UPR(mt), hsp-6, hsp-60, mitochondria

Popis súboru: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10080122/

Dostupnosť: https://discovery.ucl.ac.uk/id/eprint/10080122/1/Conradt%201-s2.0-S2211124719309532-main.pdf
https://discovery.ucl.ac.uk/id/eprint/10080122/

Mitochondrial Quality Control Mechanisms and the PHB (Prohibitin) Complex

Autori: Blanca Hernando-Rodríguez Marta Artal-Sanz

Zdroj: Cells, Vol 7, Iss 12, p 238 (2018)

Predmety: mitochondria, stress response, mitophagy, mitochondrial dynamics, mitochondrial unfolded protein response (UPR mt ), quality control, prohibitins, PHB complex, PHB-1, PHB-2, Cytology, QH573-671

Relation: https://www.mdpi.com/2073-4409/7/12/238; https://doaj.org/toc/2073-4409; https://doaj.org/article/3ef901228c9c402baf5eeeb4d2f3b105

Dostupnosť: https://doi.org/10.3390/cells7120238
https://doaj.org/article/3ef901228c9c402baf5eeeb4d2f3b105

Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt

Autori: Dejana Mokranjac Barbara Conradt Sandra Schneid a ďalší

Prispievatelia: Dejana Mokranjac Barbara Conradt Sandra Schneid a ďalší

Zdroj: Cell Reports, Vol 28, Iss 7, Pp 1659-1669.e5 (2019)
Cell Reports

Predmety: 0301 basic medicine, QH301-705.5, Mitochondrial Proteins, 03 medical and health sciences, Stress, Physiological, [SDV.BC.BC] Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], GCN-2, hsp-6, Animals, Biology (General), hsp-60, Caenorhabditis elegans, Caenorhabditis elegans Proteins, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, [INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM], Membrane Potential, Mitochondrial, 0303 health sciences, C. elegans, ATFS-1, Mitochondria, mitochondria, [SDV] Life Sciences [q-bio], Protein Transport, UPR(mt), Unfolded Protein Response, Calcium, Protein Kinases, Transcription Factors

Popis súboru: application/pdf

Prístupová URL adresa: https://discovery.ucl.ac.uk/10080122/1/Conradt%201-s2.0-S2211124719309532-main.pdf
http://www.cell.com/article/S2211124719309532/pdf
https://pubmed.ncbi.nlm.nih.gov/31412237
https://hal.science/hal-02368973v1
https://hal.science/hal-02368973v1/document
https://doi.org/10.1016/j.celrep.2019.07.049
https://doaj.org/article/bb9e8700709048ba97d48a57f558b8ab
https://www.ssrn.com/abstract=3209462
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3209462
https://pure.mpg.de/pubman/item/item_3186753_2/component/file_3188734/1-s2.0-S2211124719309532-main.pdf
https://www.sciencedirect.com/science/article/pii/S2211124719309532
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30953-2
https://pubmed.ncbi.nlm.nih.gov/31412237/
https://www.sciencedirect.com/science/article/abs/pii/S2211124719309532
https://europepmc.org/article/MED/31412237
http://hdl.handle.net/21.11116/0000-0005-898E-1
http://hdl.handle.net/21.11116/0000-0005-8990-D
https://discovery-pp.ucl.ac.uk/id/eprint/10080122/

Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans

Autori: Sara González-Hernández Annmary Paul Erinjeri Manuel Muñoz a ďalší

Prispievatelia: Sara González-Hernández Annmary Paul Erinjeri Manuel Muñoz a ďalší

Zdroj: BMC Biol
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Universidad de Sevilla (US)
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
BMC Biology, Vol 16, Iss 1, Pp 1-19 (2018)
BMC Biology

Predmety: 0301 basic medicine, QH301-705.5, Green Fluorescent Proteins, High-throughput, High-content, Worm sorting, Essential genes, Image analysis, Animals, Genetically Modified, 03 medical and health sciences, UPRmt, Prohibitins, Animals, Biology (General), Caenorhabditis elegans, Caenorhabditis elegans Proteins, 0303 health sciences, Screens, Methodology Article, UPR mt, Flow Cytometry, Mitochondria, 3. Good health, Mutation, C. elegans

Popis súboru: application/pdf; pdf

Prístupová URL adresa: https://bmcbiol.biomedcentral.com/track/pdf/10.1186/s12915-018-0496-5
https://pubmed.ncbi.nlm.nih.gov/29598825
https://idus.us.es/handle//11441/87298
https://hdl.handle.net/11441/87298
http://hdl.handle.net/10261/242283
https://doaj.org/article/73586dd4ec594b62badd23661fa8bcd7
https://link.springer.com/content/pdf/10.1186/s12915-018-0496-5.pdf
https://www.ndmrb.ox.ac.uk/research/our-research/publications/833483
https://link.springer.com/article/10.1186/s12915-018-0496-5
https://www.ncbi.nlm.nih.gov/pubmed/29598825
http://europepmc.org/articles/PMC5875015
https://figshare.com/collections/Combined_flow_cytometry_and_high-throughput_image_analysis_for_the_study_of_essential_genes_in_Caenorhabditis_elegans/4053548
https://www.biorxiv.org/content/10.1101/218735v1
https://www.biorxiv.org/content/biorxiv/early/2017/11/14/218735.full.pdf
https://www.biorxiv.org/content/early/2017/11/14/218735.full.pdf
https://ora.ox.ac.uk/objects/uuid:47b5f046-061f-4909-887a-0b4b56d04423
https://doi.org/10.1186/s12915-018-0496-5