Suchergebnisse - "Tumor Cells"

Seeing deep to map cell-biomaterial interactions via whole mount light sheet imaging and automated analytics in decellularized extracellular matrix models.

Autoren: Benavides OR VandenHeuvel SN Roy S et al.

Quelle: Biomaterials science [Biomater Sci] 2025 Sep 23; Vol. 13 (19), pp. 5442-5459. Date of Electronic Publication: 2025 Sep 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101593571 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-4849 (Electronic) Linking ISSN: 20474830 NLM ISO Abbreviation: Biomater Sci Subsets: MEDLINE

MeSH-Schlagworte: Decellularized Extracellular Matrix*/analysis , Optical Imaging*/methods , Spheroids, Cellular* , Tumor Cells, Cultured*, Humans

Selection and identification of a novel DNA aptamer for recognizing colorectal cancer stem cells.

Autoren: Li W Bing T Wang Q et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108989. Date of Electronic Publication: 2025 Sep 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Aptamers, Nucleotide*/chemistry , Aptamers, Nucleotide*/pharmacology , Neoplastic Stem Cells*/pathology , Neoplastic Stem Cells*/metabolism , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/diagnosis , Colorectal Neoplasms*/drug therapy, Humans ; SELEX Aptamer Technique ; Animals ; Mice ; Neoplastic Cells, Circulating ; Tumor Cells, Cultured

Sulphonamide derivatives with a triazine core as novel inducers of apoptosis and pyroptosis in glioblastoma multiforme cells.

Autoren: Szewczyk-Roszczenko OK Kotwica-Mojzych K Roszczenko P et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2594158. Date of Electronic Publication: 2025 Dec 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Glioblastoma*/pathology , Glioblastoma*/drug therapy , Glioblastoma*/metabolism , Pyroptosis*/drug effects , Apoptosis*/drug effects , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Sulfonamides*/pharmacology , Sulfonamides*/chemistry , Sulfonamides*/chemical synthesis , Triazines*/chemistry , Triazines*/pharmacology , Triazines*/chemical synthesis, Humans ; Zebrafish ; Animals ; Drug Screening Assays, Antitumor ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cell Line, Tumor ; Reactive Oxygen Species/metabolism ; Tumor Cells, Cultured ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/pathology ; Neoplasms, Experimental/metabolism

Comparison of Gastric Cancer Models Using Different Dimensions In Vitro.

Autoren: Zheng W Lin Y Ji L et al.

Quelle: Cancer reports (Hoboken, N.J.) [Cancer Rep (Hoboken)] 2025 Dec; Vol. 8 (12), pp. e70401.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101747728 Publication Model: Print Cited Medium: Internet ISSN: 2573-8348 (Electronic) Linking ISSN: 25738348 NLM ISO Abbreviation: Cancer Rep (Hoboken) Subsets: MEDLINE

MeSH-Schlagworte: Stomach Neoplasms*/pathology , Stomach Neoplasms*/drug therapy , Stomach Neoplasms*/genetics , Models, Biological*, Humans ; Organoids/pathology ; Organoids/drug effects ; Spheroids, Cellular/pathology ; Spheroids, Cellular/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm ; Drug Screening Assays, Antitumor/methods ; Cell Culture Techniques, Three Dimensional/methods ; Antineoplastic Agents/pharmacology ; Tumor Cells, Cultured

High-content immunofluorescence assay detecting PD-L1 expression changes in head and neck cancer patient-derived cultures.

Autoren: Ng YK Abbang SM Ye J et al.

Quelle: SLAS discovery : advancing life sciences R & D [SLAS Discov] 2025 Dec; Vol. 37, pp. 100286. Date of Electronic Publication: 2025 Nov 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101697563 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-5560 (Electronic) Linking ISSN: 24725552 NLM ISO Abbreviation: SLAS Discov Subsets: MEDLINE

MeSH-Schlagworte: B7-H1 Antigen*/metabolism , B7-H1 Antigen*/genetics , Head and Neck Neoplasms*/metabolism , Head and Neck Neoplasms*/pathology , Head and Neck Neoplasms*/genetics , Head and Neck Neoplasms*/drug therapy , Fluorescent Antibody Technique*/methods, Humans ; Cell Line, Tumor ; Tumor Cells, Cultured ; Gene Expression Regulation, Neoplastic ; High-Throughput Screening Assays/methods

Targeting MED8 enhances sorafenib sensitivity in hepatocellular carcinoma by disrupting epithelial-mesenchymal transition mechanisms.

Autoren: Li M You X Yuan T et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2574988. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Sorafenib*/pharmacology , Sorafenib*/chemistry , Epithelial-Mesenchymal Transition*/drug effects , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/pathology , Liver Neoplasms*/drug therapy , Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Mediator Complex*/metabolism , Mediator Complex*/antagonists & inhibitors , Mediator Complex*/genetics, Humans ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Dose-Response Relationship, Drug ; Structure-Activity Relationship ; Apoptosis/drug effects ; Molecular Structure ; Tumor Cells, Cultured ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects

A three-dimensional ex vivo model recapitulates in vivo features and drug resistance phenotypes in childhood acute lymphoblastic leukemia.

Autoren: Kanari M Jimenez Garcia I Steffen FD et al.

Quelle: Leukemia [Leukemia] 2025 Dec; Vol. 39 (12), pp. 2881-2894. Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

MeSH-Schlagworte: Drug Resistance, Neoplasm* , Precursor Cell Lymphoblastic Leukemia-Lymphoma*/pathology , Precursor Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy, Humans ; Tumor Microenvironment ; Child ; Animals ; Cell Movement ; Coculture Techniques ; Mice ; Mesenchymal Stem Cells/pathology ; Phenotype ; Bone Marrow/pathology ; Xenograft Model Antitumor Assays ; Tumor Cells, Cultured

Design, synthesis, and evaluation of novel pinane-based thiazolidione derivatives with anti-glioblastoma activity.

Autoren: Shi W Hu M Han J et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2553691. Date of Electronic Publication: 2025 Sep 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Glioblastoma*/pathology , Glioblastoma*/drug therapy , Glioblastoma*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Drug Design* , Thiazolidines*/pharmacology , Thiazolidines*/chemistry , Thiazolidines*/chemical synthesis, Humans ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Tumor Cells, Cultured

Integration of Metabolic Profiling and Functional Genomics Suggests IGJ as a Driver of Chemoresistance in B-ALL.

Autoren: Pachón-Meza KL Moreno-Cristancho CE Padilla-Agudelo JL et al.

Quelle: Pediatric blood & cancer [Pediatr Blood Cancer] 2025 Dec; Vol. 72 (12), pp. e32068. Date of Electronic Publication: 2025 Oct 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE

MeSH-Schlagworte: Drug Resistance, Neoplasm*/genetics , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/genetics , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/pathology , Genomics*/methods , Biomarkers, Tumor*/genetics , Biomarkers, Tumor*/metabolism , Metabolomics*/methods, Humans ; Male ; Female ; Child ; Child, Preschool ; Adolescent ; Prognosis ; Tumor Cells, Cultured

Overexpression of Nuclear Factor of Activated T-cells (NFAT) Transcription Factors Drives Chemoresistance and Poor Outcomes in Pancreatic Cancer.

Autoren: Kamioka Y Hiroshima Y Kawase W et al.

Quelle: Annals of surgical oncology [Ann Surg Oncol] 2025 Dec; Vol. 32 (13), pp. 10179-10192. Date of Electronic Publication: 2025 Aug 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 9420840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4681 (Electronic) Linking ISSN: 10689265 NLM ISO Abbreviation: Ann Surg Oncol Subsets: MEDLINE

MeSH-Schlagworte: Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/genetics , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Drug Resistance, Neoplasm* , Carcinoma, Pancreatic Ductal*/metabolism , Carcinoma, Pancreatic Ductal*/drug therapy , Carcinoma, Pancreatic Ductal*/pathology , Carcinoma, Pancreatic Ductal*/genetics , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics , Neoplasm Recurrence, Local*/pathology , Neoplasm Recurrence, Local*/metabolism , Neoplasm Recurrence, Local*/drug therapy , Neoplasm Recurrence, Local*/genetics, Humans ; Male ; Female ; Animals ; Survival Rate ; Prognosis ; Mice ; Middle Aged ; Follow-Up Studies ; Tumor Cells, Cultured ; Gene Expression Regulation, Neoplastic ; Signal Transduction ; Xenograft Model Antitumor Assays ; Aged ; Cell Proliferation ; Transcription Factors

IGF2BP3 promotes acute myeloid leukemia cell progression by regulating Semaphorin 4D stability in an m6A-dependent manner.

Autoren: Li J Shi S Zhu K et al.

Quelle: Leukemia research [Leuk Res] 2025 Dec; Vol. 159, pp. 108119. Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 7706787 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5835 (Electronic) Linking ISSN: 01452126 NLM ISO Abbreviation: Leuk Res Subsets: MEDLINE

MeSH-Schlagworte: Semaphorins*/genetics , Semaphorins*/metabolism , Leukemia, Myeloid, Acute*/pathology , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/metabolism , Antigens, CD*/genetics , Antigens, CD*/metabolism , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism, Humans ; Female ; Male ; Child ; Cell Proliferation ; Apoptosis ; Adolescent ; Gene Expression Regulation, Leukemic ; Child, Preschool ; Disease Progression ; Tumor Cells, Cultured

Discovery of a novel RSK2 inhibitor for the treatment of metastatic pancreatic cancer.

Autoren: Chung CH Hsu KC Huang MM et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2538673. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/chemical synthesis , Ribosomal Protein S6 Kinases, 90-kDa*/antagonists & inhibitors , Ribosomal Protein S6 Kinases, 90-kDa*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Drug Discovery*, Humans ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Cell Movement/drug effects ; Cell Survival/drug effects ; Epithelial-Mesenchymal Transition/drug effects ; Cell Line, Tumor ; Tumor Cells, Cultured

Immunotherapeutic targeting of NY-ESO-1 in malignant meningiomas with TCR-transduced T-cells.

Autoren: Sun MZ Contreras E Treger J et al.

Quelle: Journal of neuro-oncology [J Neurooncol] 2025 Dec; Vol. 175 (3), pp. 1079-1089. Date of Electronic Publication: 2025 Aug 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE

MeSH-Schlagworte: Meningioma*/therapy , Meningioma*/immunology , Meningioma*/pathology , Meningioma*/metabolism , Membrane Proteins*/metabolism , Membrane Proteins*/immunology , Meningeal Neoplasms*/therapy , Meningeal Neoplasms*/immunology , Meningeal Neoplasms*/pathology , Meningeal Neoplasms*/metabolism , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , T-Lymphocytes*/transplantation , Receptors, Antigen, T-Cell*/metabolism , Receptors, Antigen, T-Cell*/genetics , Receptors, Antigen, T-Cell*/immunology , Antigens, Neoplasm*/metabolism , Antigens, Neoplasm*/immunology , Immunotherapy, Adoptive*/methods, Animals ; Humans ; Mice ; Female ; Male ; Mice, Inbred NOD ; Mice, SCID ; Middle Aged ; Xenograft Model Antitumor Assays ; Aged ; Tumor Cells, Cultured ; Cell Line, Tumor ; Coculture Techniques

SPRY1 Interaction with CBL Promotes Vimentin Stabilization to Enhance Malignant Progression and Metastasis in Wilms Tumor.

Autoren: Huang F Gao H Lu Z et al.

Quelle: Annals of surgical oncology [Ann Surg Oncol] 2025 Dec; Vol. 32 (13), pp. 10193-10212. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 9420840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4681 (Electronic) Linking ISSN: 10689265 NLM ISO Abbreviation: Ann Surg Oncol Subsets: MEDLINE

MeSH-Schlagworte: Wilms Tumor*/metabolism , Wilms Tumor*/pathology , Wilms Tumor*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Kidney Neoplasms*/metabolism , Kidney Neoplasms*/pathology , Kidney Neoplasms*/genetics , Vimentin*/metabolism , Proto-Oncogene Proteins c-cbl*/metabolism , Proto-Oncogene Proteins c-cbl*/genetics , Phosphoproteins*/metabolism , Phosphoproteins*/genetics , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics, Humans ; Animals ; Mice ; Cell Proliferation ; Prognosis ; Cell Movement ; Mice, Nude ; Disease Progression ; Female ; Tumor Cells, Cultured ; Mice, Inbred BALB C ; Survival Rate ; Male ; Gene Expression Regulation, Neoplastic ; Xenograft Model Antitumor Assays

Farnesiferol C enhances the effects of chemotherapy and ionising radiation in human melanoma cells via targeting topoisomerase II alpha.

Autoren: Moosavinejad N Nasiri Sarvi Z Gholamhosseinian H et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2565463. Date of Electronic Publication: 2025 Sep 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: DNA Topoisomerases, Type II*/metabolism , Melanoma*/pathology , Melanoma*/drug therapy , Melanoma*/metabolism , Topoisomerase II Inhibitors*/pharmacology , Topoisomerase II Inhibitors*/chemistry , Topoisomerase II Inhibitors*/isolation & purification , Poly-ADP-Ribose Binding Proteins*/antagonists & inhibitors , Poly-ADP-Ribose Binding Proteins*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis, Humans ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Structure ; Dose-Response Relationship, Drug ; Apoptosis/drug effects ; Radiation, Ionizing ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cell Line, Tumor ; Tumor Cells, Cultured ; Molecular Docking Simulation ; Temozolomide/pharmacology

Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies.

Autoren: Wawruszak A Luszczki J Bartuzi D et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2458554. Date of Electronic Publication: 2025 Feb 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Sirtuin 1*/antagonists & inhibitors , Sirtuin 1*/metabolism , Paclitaxel*/pharmacology , Paclitaxel*/chemistry , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/metabolism , Histone Deacetylase Inhibitors*/pharmacology , Histone Deacetylase Inhibitors*/chemistry , Histone Deacetylase Inhibitors*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Carbazoles*/pharmacology , Carbazoles*/chemistry , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/chemistry, Humans ; Cell Proliferation/drug effects ; Animals ; Zebrafish ; Female ; Drug Screening Assays, Antitumor ; Apoptosis/drug effects ; Dose-Response Relationship, Drug ; Molecular Structure ; Structure-Activity Relationship ; Cell Line, Tumor ; Tumor Cells, Cultured

β-lapachone impairs viability, migration, and epithelial-mesenchymal transition in mammary tumor spheroids.

Autoren: Coelho LL Vianna MM da Silva DM et al.

Quelle: BMC cancer [BMC Cancer] 2025 Nov 26; Vol. 25 (1), pp. 1826. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

MeSH-Schlagworte: Naphthoquinones*/pharmacology , Epithelial-Mesenchymal Transition*/drug effects , Spheroids, Cellular*/drug effects , Spheroids, Cellular*/pathology , Cell Movement*/drug effects , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism, Humans ; Female ; Cell Survival/drug effects ; MCF-7 Cells ; Cadherins/metabolism ; Vimentin/metabolism ; Tumor Cells, Cultured

Mechanism of METTL14-mediated RAD21 mRNA epigenetic transcriptome modification in inhibiting thyroid cancer development.

Autoren: Ge Y Qin C Xiao M

Quelle: World journal of surgical oncology [World J Surg Oncol] 2025 Nov 14; Vol. 23 (1), pp. 434. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819 (Electronic) Linking ISSN: 14777819 NLM ISO Abbreviation: World J Surg Oncol Subsets: MEDLINE

MeSH-Schlagworte: Methyltransferases*/metabolism , Methyltransferases*/genetics , Thyroid Neoplasms*/genetics , Thyroid Neoplasms*/pathology , Thyroid Neoplasms*/metabolism , Gene Expression Regulation, Neoplastic* , Epigenesis, Genetic* , Ribonucleoproteins*/genetics , Ribonucleoproteins*/metabolism , Transcriptome*, Humans ; Animals ; Mice ; Cell Proliferation ; Apoptosis ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Mice, Nude ; Cell Movement ; Female ; Male ; Prognosis ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

Recovery of glioblastoma cells derived from patients after a decade of cryopreservation for drug response studies.

Autoren: Khotchawan W Lorthongpanich C Kheolamai P et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 11; Vol. 15 (1), pp. 39424. Date of Electronic Publication: 2025 Nov 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Glioblastoma*/pathology , Glioblastoma*/drug therapy , Glioblastoma*/metabolism , Cryopreservation*/methods , Brain Neoplasms*/pathology , Brain Neoplasms*/drug therapy, Humans ; Temozolomide/pharmacology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor/methods ; Spheroids, Cellular/drug effects ; Tumor Cells, Cultured ; Cell Line, Tumor ; Cell Culture Techniques/methods

HROB is a novel prognostic biomarker correlated with immune cell infiltration and tumor progression in lung adenocarcinoma.

Autoren: Zhu Y Wu C Li Q et al.

Quelle: World journal of surgical oncology [World J Surg Oncol] 2025 Nov 03; Vol. 23 (1), pp. 415. Date of Electronic Publication: 2025 Nov 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819 (Electronic) Linking ISSN: 14777819 NLM ISO Abbreviation: World J Surg Oncol Subsets: MEDLINE

MeSH-Schlagworte: Adenocarcinoma of Lung*/pathology , Adenocarcinoma of Lung*/immunology , Adenocarcinoma of Lung*/genetics , Adenocarcinoma of Lung*/metabolism , Adenocarcinoma of Lung*/mortality , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/immunology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Lung Neoplasms*/mortality , Lymphocytes, Tumor-Infiltrating*/immunology, Humans ; Prognosis ; Cell Proliferation ; Disease Progression ; Cell Movement ; Gene Expression Regulation, Neoplastic ; Tumor Cells, Cultured ; Survival Rate ; Male ; Female ; Cell Line, Tumor