Výsledky vyhledávání - "Transmembrane Activator and CAML Interactor Protein"

Genetically engineered extracellular vesicles expressing decoy protein TACI provide a therapeutic effect in systemic lupus erythematosus mouse model.

Autoři: Cai M Tian F Han J a další

Zdroj: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2025 Aug 10; Vol. 384, pp. 113886. Date of Electronic Publication: 2025 May 25.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

Výrazy ze slovníku MeSH: Extracellular Vesicles*/genetics , Extracellular Vesicles*/metabolism , Lupus Erythematosus, Systemic*/therapy , Lupus Erythematosus, Systemic*/immunology , Lupus Erythematosus, Systemic*/pathology , Transmembrane Activator and CAML Interactor Protein*/genetics , Transmembrane Activator and CAML Interactor Protein*/metabolism, Animals ; Disease Models, Animal ; B-Cell Activating Factor/metabolism ; Female ; Mice ; Humans ; NF-kappa B/metabolism ; Genetic Engineering ; Recombinant Fusion Proteins/genetics ; B-Cell Maturation Antigen/metabolism ; Signal Transduction ; Tumor Necrosis Factor Ligand Superfamily Member 13/metabolism

CAR-T cell targeting three receptors on autoreactive B cells for systemic lupus erythematosus therapy.

Autoři: Uppin V Gibbons H Troje M a další

Zdroj: Journal of autoimmunity [J Autoimmun] 2025 Feb; Vol. 151, pp. 103369. Date of Electronic Publication: 2025 Jan 19.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Academic Press Country of Publication: England NLM ID: 8812164 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9157 (Electronic) Linking ISSN: 08968411 NLM ISO Abbreviation: J Autoimmun Subsets: MEDLINE

Výrazy ze slovníku MeSH: Lupus Erythematosus, Systemic*/therapy , Lupus Erythematosus, Systemic*/immunology , B-Lymphocytes*/immunology , B-Lymphocytes*/metabolism , B-Cell Maturation Antigen*/immunology , B-Cell Maturation Antigen*/genetics , B-Cell Maturation Antigen*/metabolism , B-Cell Activation Factor Receptor*/immunology , B-Cell Activation Factor Receptor*/genetics , B-Cell Activation Factor Receptor*/metabolism , Immunotherapy, Adoptive*/methods , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Transmembrane Activator and CAML Interactor Protein*/immunology , Transmembrane Activator and CAML Interactor Protein*/genetics , Transmembrane Activator and CAML Interactor Protein*/metabolism, Animals ; Humans ; Mice ; B-Cell Activating Factor/genetics ; B-Cell Activating Factor/immunology ; B-Cell Activating Factor/metabolism ; Disease Models, Animal ; Mice, Inbred MRL lpr ; Female ; Autoimmunity ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/transplantation

Pathogenic TNFRSF13B Variant in an Adult Japanese Patient with Common Variable Immunodeficiency.

Autoři: Nakamura N Ikunari R Tanaka Y a další

Zdroj: Internal medicine (Tokyo, Japan) [Intern Med] 2025 Mar 01; Vol. 64 (5), pp. 753-757. Date of Electronic Publication: 2024 Jul 11.

Způsob vydávání: Journal Article; Case Reports

Informace o časopise: Publisher: Japanese Society of Internal Medicine Country of Publication: Japan NLM ID: 9204241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7235 (Electronic) Linking ISSN: 09182918 NLM ISO Abbreviation: Intern Med Subsets: MEDLINE

Výrazy ze slovníku MeSH: Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/diagnosis , Common Variable Immunodeficiency*/complications , Transmembrane Activator and CAML Interactor Protein*/genetics, Humans ; Female ; Middle Aged ; Agammaglobulinemia/genetics ; Agammaglobulinemia/diagnosis ; Asian People/genetics ; Japan ; Frameshift Mutation/genetics ; Diagnosis, Differential ; Respiratory Tract Infections/genetics ; East Asian People

Efficacy and safety of telitacicept in IgA nephropathy: a real-world study.

Autoři: Dong L Yang D Qin A a další

Zdroj: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2449580. Date of Electronic Publication: 2025 Jan 08.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

Výrazy ze slovníku MeSH: Glomerulonephritis, IGA*/drug therapy , Proteinuria*/drug therapy , Proteinuria*/etiology , Glomerular Filtration Rate*/drug effects, Humans ; Female ; Male ; Adult ; Middle Aged ; Immunosuppressive Agents/therapeutic use ; Treatment Outcome ; Recombinant Fusion Proteins/therapeutic use ; Recombinant Fusion Proteins/adverse effects ; Recombinant Fusion Proteins/administration & dosage ; Propensity Score ; Transmembrane Activator and CAML Interactor Protein ; Retrospective Studies

Genomic and clinical characterization of adult CVID patients: results from a single-centre turkish cohort.

Autoři: Yilmaz Tekinhatun H Firtina S Sayitoglu M a další

Zdroj: Immunologic research [Immunol Res] 2025 Oct 10; Vol. 73 (1), pp. 141. Date of Electronic Publication: 2025 Oct 10.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 8611087 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-0755 (Electronic) Linking ISSN: 0257277X NLM ISO Abbreviation: Immunol Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/diagnosis, Humans ; Adult ; Female ; Male ; Middle Aged ; Turkey ; Exome Sequencing ; Phenotype ; Cohort Studies ; Genomics/methods ; Mutation ; Young Adult ; Genetic Predisposition to Disease ; Transmembrane Activator and CAML Interactor Protein/genetics

Discovery of core genes for systemic lupus erythematosus via genome-wide aggregated trans-effects analysis.

Autoři: Iakovliev A Castellini-Pérez O Erabadda B a další

Korporace: Iakovliev A Castellini-Pérez O Erabadda B a další

Zdroj: Genes and immunity [Genes Immun] 2025 Oct; Vol. 26 (5), pp. 497-508. Date of Electronic Publication: 2025 Sep 03.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100953417 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5470 (Electronic) Linking ISSN: 14664879 NLM ISO Abbreviation: Genes Immun Subsets: MEDLINE

Výrazy ze slovníku MeSH: Lupus Erythematosus, Systemic*/genetics, Humans ; Genome-Wide Association Study ; Genetic Predisposition to Disease ; Interferons/metabolism ; Transmembrane Activator and CAML Interactor Protein/genetics

Unique and redundant roles of mouse BCMA, TACI, BAFF, APRIL, and IL-6 in supporting antibody-producing cells in different tissues.

Autoři: Eslami M Schuepbach-Mallepell S Diana D a další

Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 16; Vol. 121 (29), pp. e2404309121. Date of Electronic Publication: 2024 Jul 11.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Výrazy ze slovníku MeSH: B-Cell Activating Factor*/immunology , B-Cell Activating Factor*/metabolism , B-Cell Activating Factor*/genetics , Tumor Necrosis Factor Ligand Superfamily Member 13*/metabolism , Tumor Necrosis Factor Ligand Superfamily Member 13*/immunology , Tumor Necrosis Factor Ligand Superfamily Member 13*/genetics , B-Cell Maturation Antigen*/immunology , B-Cell Maturation Antigen*/metabolism , Transmembrane Activator and CAML Interactor Protein*/metabolism , Transmembrane Activator and CAML Interactor Protein*/genetics , Transmembrane Activator and CAML Interactor Protein*/immunology , Interleukin-6*/metabolism , Interleukin-6*/immunology , B-Cell Activation Factor Receptor*/metabolism , B-Cell Activation Factor Receptor*/immunology , B-Cell Activation Factor Receptor*/genetics, Animals ; Mice ; Plasma Cells/immunology ; Plasma Cells/metabolism ; Mice, Knockout ; Antibody-Producing Cells/immunology ; Antibody-Producing Cells/metabolism ; Mice, Inbred C57BL

Posttranscriptional control of the B cell receptor by HuR is essential for innate B cell maintenance and function.

Autoři: Capitan-Sobrino D Mouysset M Maloudi O a další

Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Sep 16; Vol. 122 (37), pp. e2421149122. Date of Electronic Publication: 2025 Sep 12.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Výrazy ze slovníku MeSH: ELAV-Like Protein 1*/genetics , ELAV-Like Protein 1*/metabolism , ELAV-Like Protein 1*/immunology , Receptors, Antigen, B-Cell*/metabolism , Receptors, Antigen, B-Cell*/genetics , Receptors, Antigen, B-Cell*/immunology , B-Lymphocytes*/immunology , B-Lymphocytes*/metabolism , Immunity, Innate* , RNA Processing, Post-Transcriptional*, Animals ; Mice ; Mice, Knockout ; Transmembrane Activator and CAML Interactor Protein/genetics ; Transmembrane Activator and CAML Interactor Protein/metabolism ; Transmembrane Activator and CAML Interactor Protein/immunology ; B-Cell Activation Factor Receptor/genetics ; B-Cell Activation Factor Receptor/metabolism ; B-Cell Activation Factor Receptor/immunology ; Signal Transduction ; Mice, Inbred C57BL

Highly ordered clustering of TNFα and BAFF ligand-receptor-intracellular adaptor complexes on a lipid membrane.

Autoři: Lim CS Lee J Kim JW a další

Zdroj: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5551. Date of Electronic Publication: 2025 Jul 01.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy ze slovníku MeSH: Receptors, Tumor Necrosis Factor, Type I*/metabolism , Receptors, Tumor Necrosis Factor, Type I*/chemistry , Receptors, Tumor Necrosis Factor, Type I*/genetics , Tumor Necrosis Factor-alpha*/metabolism , Tumor Necrosis Factor-alpha*/chemistry , B-Cell Activating Factor*/metabolism , B-Cell Activating Factor*/genetics , B-Cell Activating Factor*/chemistry , B-Cell Activation Factor Receptor*/metabolism , B-Cell Activation Factor Receptor*/chemistry , B-Cell Activation Factor Receptor*/genetics , Cell Membrane*/metabolism , Membrane Lipids*/metabolism , Membrane Lipids*/chemistry, Humans ; Protein Binding ; Ligands ; TNF Receptor-Associated Factor 3/metabolism ; TNF Receptor-Associated Factor 3/chemistry ; Protein Multimerization ; Transmembrane Activator and CAML Interactor Protein/metabolism ; Transmembrane Activator and CAML Interactor Protein/chemistry

Dual variants of uncertain significance in a case of hyper-IgM syndrome: implications for diagnosis and management.

Autoři: Agrebi N Mackeh R Alsabbagh M a další

Zdroj: Frontiers in immunology [Front Immunol] 2025 Jun 02; Vol. 16, pp. 1594636. Date of Electronic Publication: 2025 Jun 02 (Print Publication: 2025).

Způsob vydávání: Journal Article; Case Reports

Informace o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Hyper-IgM Immunodeficiency Syndrome*/diagnosis , Hyper-IgM Immunodeficiency Syndrome*/genetics , Hyper-IgM Immunodeficiency Syndrome*/therapy , Hyper-IgM Immunodeficiency Syndrome*/immunology , I-kappa B Kinase*/genetics , Mutation*, Humans ; Male ; Female ; Homozygote ; Child ; Transmembrane Activator and CAML Interactor Protein

TACI and endogenous APRIL in B cell maturation.

Autoři: Garcia-Carmona Y Fribourg M Sowa A a další

Zdroj: Clinical immunology (Orlando, Fla.) [Clin Immunol] 2023 Aug; Vol. 253, pp. 109689. Date of Electronic Publication: 2023 Jul 06.

Způsob vydávání: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 100883537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-7035 (Electronic) Linking ISSN: 15216616 NLM ISO Abbreviation: Clin Immunol Subsets: MEDLINE

Výrazy ze slovníku MeSH: B-Cell Maturation Antigen* , Transmembrane Activator and CAML Interactor Protein*/genetics, Mice ; Animals ; Humans ; B-Lymphocytes ; Plasma Cells ; Tumor Necrosis Factor Ligand Superfamily Member 13/genetics ; Tumor Necrosis Factor Ligand Superfamily Member 13/metabolism ; B-Cell Activating Factor

Features of Isoforms of Human Soluble TACI.

Autoři: Fichtner ML Rübsamen H Smolle M a další

Zdroj: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2023 Jul 15; Vol. 211 (2), pp. 199-208.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

Výrazy ze slovníku MeSH: B-Lymphocytes* , Transmembrane Activator and CAML Interactor Protein*/genetics, Humans ; Alternative Splicing ; B-Cell Activating Factor/metabolism ; B-Cell Activation Factor Receptor/genetics ; Cytokines/genetics ; Protein Isoforms/genetics ; Tumor Necrosis Factor Ligand Superfamily Member 13/genetics ; Tumor Necrosis Factor Ligand Superfamily Member 13/metabolism

A novel frameshift variant in TNFRSF13B in a Chinese patient with late-onset combined immunodeficiency.

Autoři: Miao J Shen M

Zdroj: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2023 Jun 01; Vol. 62 (6), pp. e196-e198.

Způsob vydávání: Case Reports; Letter; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE

Výrazy ze slovníku MeSH: Transmembrane Activator and CAML Interactor Protein*, Humans ; East Asian People ; Homozygote ; Mutation ; Pedigree ; Severe Combined Immunodeficiency/genetics

TNFRSF13B/TACI Mutations in Patients with Chronic Rhinosinusitis with Nasal Polyps.

Autoři: Tsiouma GK Skoulakis CE Lachanas VA a další

Zdroj: American journal of rhinology & allergy [Am J Rhinol Allergy] 2023 Jan; Vol. 37 (1), pp. 74-77. Date of Electronic Publication: 2022 Oct 27.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101490775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1945-8932 (Electronic) Linking ISSN: 19458932 NLM ISO Abbreviation: Am J Rhinol Allergy Subsets: MEDLINE

Výrazy ze slovníku MeSH: Nasal Polyps*/genetics , Rhinitis*/genetics , Sinusitis*/genetics , Transmembrane Activator and CAML Interactor Protein*/genetics, Female ; Humans ; Male ; Middle Aged ; Chronic Disease ; Cohort Studies ; Mutation ; Adolescent ; Young Adult ; Adult ; Aged ; Aged, 80 and over

Contributions of each of the BAFF receptors to the lymphocyte profiles in C57BL/6 mice.

Autoři: Stohl W Wu Y Stohl M

Zdroj: Immunology [Immunology] 2024 Dec; Vol. 173 (4), pp. 689-711. Date of Electronic Publication: 2024 Aug 31.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE

Výrazy ze slovníku MeSH: B-Cell Activating Factor*/metabolism , B-Cell Activating Factor*/genetics , B-Cell Activating Factor*/immunology , Mice, Knockout* , Mice, Inbred C57BL* , B-Cell Activation Factor Receptor*/metabolism , B-Cell Activation Factor Receptor*/genetics, Animals ; Mice ; Transmembrane Activator and CAML Interactor Protein/genetics ; Transmembrane Activator and CAML Interactor Protein/metabolism ; B-Lymphocyte Subsets/immunology ; B-Lymphocyte Subsets/metabolism ; Forkhead Transcription Factors/metabolism ; Forkhead Transcription Factors/genetics ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; Mice, Transgenic ; B-Cell Maturation Antigen/immunology ; B-Cell Maturation Antigen/genetics ; B-Cell Maturation Antigen/metabolism

The effects of B-cell-activating factor on the population size, maturation and function of murine natural killer cells.

Autoři: Quah PS Sutton V Whitlock E a další

Zdroj: Immunology and cell biology [Immunol Cell Biol] 2022 Nov; Vol. 100 (10), pp. 761-776. Date of Electronic Publication: 2022 Oct 08.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 8706300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1711 (Electronic) Linking ISSN: 08189641 NLM ISO Abbreviation: Immunol Cell Biol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Transmembrane Activator and CAML Interactor Protein*/genetics , Lupus Erythematosus, Systemic*, Mice ; Animals ; Population Density ; Interleukin-4 ; Mice, Transgenic ; Killer Cells, Natural/metabolism

A first-in-human, randomized study of the safety, pharmacokinetics and pharmacodynamics of povetacicept, an enhanced dual BAFF/APRIL antagonist, in healthy adults.

Autoři: Davies R Peng SL Lickliter J a další

Zdroj: Clinical and translational science [Clin Transl Sci] 2024 Nov; Vol. 17 (11), pp. e70055.

Způsob vydávání: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I

Informace o časopise: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

Výrazy ze slovníku MeSH: B-Cell Activating Factor*/antagonists & inhibitors , B-Cell Activating Factor*/immunology , Tumor Necrosis Factor Ligand Superfamily Member 13*/antagonists & inhibitors , Tumor Necrosis Factor Ligand Superfamily Member 13*/immunology , Recombinant Fusion Proteins*/pharmacokinetics , Recombinant Fusion Proteins*/administration & dosage , Recombinant Fusion Proteins*/pharmacology , Recombinant Fusion Proteins*/adverse effects , Healthy Volunteers*, Humans ; Adult ; Male ; Female ; Middle Aged ; Young Adult ; Transmembrane Activator and CAML Interactor Protein/immunology ; Double-Blind Method ; Dose-Response Relationship, Drug

Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells.

Autoři: Smulski CR Zhang L Burek M a další

Zdroj: Cell reports [Cell Rep] 2022 Mar 29; Vol. 38 (13), pp. 110583.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Výrazy ze slovníku MeSH: Common Variable Immunodeficiency*/genetics , Common Variable Immunodeficiency*/metabolism , Transmembrane Activator and CAML Interactor Protein*/genetics , Transmembrane Activator and CAML Interactor Protein*/metabolism, B-Lymphocytes ; Cell Proliferation ; Humans ; Ligands

A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers.

Autoři: Wong DP Roy NK Zhang K a další

Zdroj: Nature communications [Nat Commun] 2022 Jan 11; Vol. 13 (1), pp. 217. Date of Electronic Publication: 2022 Jan 11.

Způsob vydávání: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy ze slovníku MeSH: B-Cell Activating Factor/*genetics , B-Cell Activation Factor Receptor/*genetics , B-Cell Maturation Antigen/*genetics , Lymphoma, Mantle-Cell/*therapy , Multiple Myeloma/*therapy , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*therapy , Transmembrane Activator and CAML Interactor Protein/*genetics, Animals ; Antigens, CD/genetics ; Antigens, CD/immunology ; Antigens, Differentiation, T-Lymphocyte/genetics ; Antigens, Differentiation, T-Lymphocyte/immunology ; B-Cell Activating Factor/immunology ; B-Cell Activation Factor Receptor/immunology ; B-Cell Maturation Antigen/immunology ; B-Lymphocytes/immunology ; B-Lymphocytes/pathology ; Cell Line, Tumor ; Coculture Techniques ; Cytotoxicity, Immunologic ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lectins, C-Type/genetics ; Lectins, C-Type/immunology ; Lymphocyte Activation ; Lymphoma, Mantle-Cell/genetics ; Lymphoma, Mantle-Cell/immunology ; Lymphoma, Mantle-Cell/pathology ; Lysosomal-Associated Membrane Protein 1/genetics ; Lysosomal-Associated Membrane Protein 1/immunology ; Male ; Mice ; Multiple Myeloma/genetics ; Multiple Myeloma/immunology ; Multiple Myeloma/pathology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/immunology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Protein Binding ; Receptors, Chimeric Antigen/genetics ; Receptors, Chimeric Antigen/immunology ; Signal Transduction ; T-Lymphocytes/immunology ; T-Lymphocytes/transplantation ; Transmembrane Activator and CAML Interactor Protein/immunology ; Xenograft Model Antitumor Assays

TACI deficiency - a complex system out of balance.

Autoři: Salzer U Grimbacher B

Zdroj: Current opinion in immunology [Curr Opin Immunol] 2021 Aug; Vol. 71, pp. 81-88. Date of Electronic Publication: 2021 Jul 08.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't; Review

Informace o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 8900118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0372 (Electronic) Linking ISSN: 09527915 NLM ISO Abbreviation: Curr Opin Immunol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Common Variable Immunodeficiency/*immunology , Transmembrane Activator and CAML Interactor Protein/*immunology, Common Variable Immunodeficiency/genetics ; Humans ; Transmembrane Activator and CAML Interactor Protein/deficiency ; Transmembrane Activator and CAML Interactor Protein/genetics