Výsledky vyhľadávania - "Transcription"

snRNA-seq reveals key transcription factors in the inflammatory response of microglia after intracerebral hemorrhage.

Autori: Wu Z Chen D Chen S a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Nov 20; Vol. 15 (1), pp. 40961. Date of Electronic Publication: 2025 Nov 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Microglia*/metabolism , Microglia*/pathology , Cerebral Hemorrhage*/genetics , Cerebral Hemorrhage*/metabolism , Cerebral Hemorrhage*/pathology , Inflammation*/genetics , Inflammation*/metabolism , Inflammation*/pathology , Transcription Factors*/metabolism , Transcription Factors*/genetics, Animals ; Mice ; Male ; Disease Models, Animal ; Mice, Inbred C57BL ; RNA-Seq ; Transcriptome ; STAT1 Transcription Factor/metabolism ; STAT1 Transcription Factor/genetics ; Gene Expression Profiling ; STAT2 Transcription Factor/metabolism ; STAT2 Transcription Factor/genetics ; Sequence Analysis, RNA ; Gene Expression Regulation

CD4+ T-cell transcription factors as early predictors of phenoconversion in idiopathic rapid eye movement sleep behaviour disorder.

Autori: Pinoli M Terzaghi M Marino F a ďalší

Zdroj: F1000Research [F1000Res] 2025 Oct 06; Vol. 14, pp. 683. Date of Electronic Publication: 2025 Oct 06 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: F1000 Research Ltd Country of Publication: England NLM ID: 101594320 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-1402 (Electronic) Linking ISSN: 20461402 NLM ISO Abbreviation: F1000Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: CD4-Positive T-Lymphocytes*/metabolism , REM Sleep Behavior Disorder*/metabolism , REM Sleep Behavior Disorder*/genetics , REM Sleep Behavior Disorder*/diagnosis , Transcription Factors*/metabolism , Transcription Factors*/genetics, Humans ; Male ; Female ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Middle Aged ; Aged ; RNA, Messenger/metabolism ; RNA, Messenger/genetics ; Parkinson Disease ; GATA3 Transcription Factor/genetics ; GATA3 Transcription Factor/metabolism ; Biomarkers/metabolism ; STAT1 Transcription Factor/genetics ; STAT1 Transcription Factor/metabolism ; Adult

Single-molecule Microscopy Reveals That TFIIE Subunits Dynamically Interact With Preinitiation Complexes in a Manner Impacted by TFIIH.

Autori: Archuleta SR Miller RC Mirita JA a ďalší

Zdroj: Journal of molecular biology [J Mol Biol] 2025 Dec 15; Vol. 437 (24), pp. 169528. Date of Electronic Publication: 2025 Nov 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Transcription Factor TFIIH*/metabolism , Transcription Factor TFIIH*/genetics , Transcription Factors, TFII*/metabolism , Transcription Factors, TFII*/genetics , Transcription Factors, TFII*/chemistry , RNA Polymerase II*/metabolism , RNA Polymerase II*/genetics, Humans ; Single Molecule Imaging/methods ; Protein Binding ; Protein Subunits/metabolism ; Transcription Initiation, Genetic ; Microscopy, Fluorescence

Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis.

Autori: Zhou L Wu D Zhou Y a ďalší

Zdroj: The Journal of experimental medicine [J Exp Med] 2025 Dec 01; Vol. 222 (12). Date of Electronic Publication: 2025 Oct 15.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Janus Kinase 2*/genetics , Janus Kinase 2*/metabolism , Receptors, Aryl Hydrocarbon*/metabolism , Receptors, Aryl Hydrocarbon*/genetics , Thrombocythemia, Essential*/genetics , Thrombocythemia, Essential*/pathology , Thrombocythemia, Essential*/metabolism , Thrombosis*/genetics , Thrombosis*/pathology , Thrombosis*/metabolism , Basic Helix-Loop-Helix Transcription Factors*/metabolism , Basic Helix-Loop-Helix Transcription Factors*/genetics, Humans ; Animals ; Heterozygote ; Mice ; Polycythemia Vera/genetics ; Polycythemia Vera/pathology ; STAT1 Transcription Factor/metabolism ; STAT5 Transcription Factor/metabolism ; Mutation ; Megakaryocytes/metabolism ; Megakaryocytes/pathology ; Blood Platelets/metabolism ; Cyclooxygenase 2/metabolism

A role for human senataxin in contending with pausing and backtracking during transcript elongation.

Autori: Han Z Fu S Johansen JV a ďalší

Zdroj: Molecular cell [Mol Cell] 2025 Nov 20; Vol. 85 (22), pp. 4166-4182.e10. Date of Electronic Publication: 2025 Nov 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

Výrazy zo slovníka MeSH: RNA Helicases*/genetics , RNA Helicases*/metabolism , RNA Polymerase II*/metabolism , RNA Polymerase II*/genetics , Transcription Elongation, Genetic* , Transcription, Genetic*, Humans ; Multifunctional Enzymes/genetics ; Multifunctional Enzymes/metabolism ; R-Loop Structures ; Transcription Termination, Genetic ; Mutation ; RNA/genetics ; RNA/metabolism ; DNA Helicases

The transcription factor NFIL3 drives innate lymphoid cell specification from lymphoid progenitors.

Autori: Léger J Artano E Coulais D a ďalší

Zdroj: Immunity [Immunity] 2025 Nov 11; Vol. 58 (11), pp. 2685-2703.e6. Date of Electronic Publication: 2025 Oct 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

Výrazy zo slovníka MeSH: Immunity, Innate* , Lymphoid Progenitor Cells*/immunology , Lymphoid Progenitor Cells*/cytology , Lymphoid Progenitor Cells*/metabolism , Basic-Leucine Zipper Transcription Factors*/genetics , Basic-Leucine Zipper Transcription Factors*/metabolism , Basic-Leucine Zipper Transcription Factors*/immunology , Lymphocytes*/immunology , Lymphocytes*/cytology, Animals ; Mice ; Mice, Knockout ; Cell Lineage/immunology ; Cell Differentiation/immunology ; Inhibitor of Differentiation Protein 2/genetics ; Inhibitor of Differentiation Protein 2/metabolism ; Mice, Inbred C57BL ; GATA3 Transcription Factor/metabolism ; GATA3 Transcription Factor/genetics ; Killer Cells, Natural/immunology ; Cells, Cultured ; Promyelocytic Leukemia Zinc Finger Protein ; Hepatocyte Nuclear Factor 1-alpha

Targeting TAZ-TEAD in minimal residual disease enhances the duration of targeted therapy in melanoma models.

Autori: Ott CA Purwin TJ Chen PY a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Nov 05; Vol. 16 (1), pp. 9655. Date of Electronic Publication: 2025 Nov 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Melanoma*/drug therapy , Melanoma*/genetics , Melanoma*/metabolism , Melanoma*/pathology , Transcription Factors*/metabolism , Transcription Factors*/genetics , Transcription Factors*/antagonists & inhibitors , Neoplasm, Residual*/drug therapy, Humans ; SOXE Transcription Factors/genetics ; SOXE Transcription Factors/metabolism ; Animals ; Cell Line, Tumor ; Mice ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors ; Proto-Oncogene Proteins B-raf/metabolism ; Drug Resistance, Neoplasm/drug effects ; Xenograft Model Antitumor Assays ; Protein Kinase Inhibitors/pharmacology ; Transcriptional Coactivator with PDZ-Binding Motif Proteins ; Molecular Targeted Therapy ; Connective Tissue Growth Factor/metabolism ; Connective Tissue Growth Factor/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; TEA Domain Transcription Factors ; Female ; Trans-Activators

Single cis-elements in brassinosteroid-induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA-binding domain.

Autori: Nosaki S Ohtsuka M Nakano T a ďalší

Zdroj: FEBS letters [FEBS Lett] 2025 Nov; Vol. 599 (22), pp. 3369-3380. Date of Electronic Publication: 2025 Aug 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE

Výrazy zo slovníka MeSH: Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , Arabidopsis Proteins*/chemistry , Brassinosteroids*/pharmacology , Brassinosteroids*/metabolism , Arabidopsis*/genetics , Arabidopsis*/metabolism , Arabidopsis*/drug effects , Gene Expression Regulation, Plant*/drug effects , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/genetics , DNA-Binding Proteins*/chemistry , Nuclear Proteins*/metabolism , Nuclear Proteins*/genetics , Nuclear Proteins*/chemistry , Transcription Factors*/metabolism , Transcription Factors*/genetics , Transcription Factors*/chemistry, Oxidation-Reduction ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Up-Regulation/drug effects ; Protein Domains ; Protein Binding

Stability Matters: Revealing Causal Roles of G-Quadruplexes (G4s) in Regulation of Chromatin and Transcription.

Autori: Xiao K Zhang R Tao T a ďalší

Zdroj: Genes [Genes (Basel)] 2025 Oct 17; Vol. 16 (10). Date of Electronic Publication: 2025 Oct 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

Výrazy zo slovníka MeSH: G-Quadruplexes* , Chromatin*/genetics , Chromatin*/chemistry , Transcription, Genetic*, Humans ; Gene Expression Regulation ; Epigenesis, Genetic ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Transcription Initiation Site

NKX6-3 in B-Cell Progenitor Differentiation and Leukemia.

Autori: Nagel S Meyer C Pommerenke C

Zdroj: Genes [Genes (Basel)] 2025 Oct 14; Vol. 16 (10). Date of Electronic Publication: 2025 Oct 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Homeodomain Proteins*/genetics , Homeodomain Proteins*/metabolism , Transcription Factors*/genetics , Transcription Factors*/metabolism , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/genetics , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/pathology , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism, Humans ; Cell Differentiation/genetics ; Cell Line, Tumor ; Gene Regulatory Networks ; Gene Expression Regulation, Leukemic ; Pre-B-Cell Leukemia Transcription Factor 1/genetics ; Pre-B-Cell Leukemia Transcription Factor 1/metabolism ; B-Lymphocytes/metabolism ; Basic Helix-Loop-Helix Transcription Factors

MdHSFA2 enhances heat stress tolerance through promoting the MdGolS4 transcription in apple.

Autori: Li M Zhang X Zuo D a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Oct 10; Vol. 15 (1), pp. 35436. Date of Electronic Publication: 2025 Oct 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Malus*/genetics , Malus*/physiology , Malus*/metabolism , Plant Proteins*/genetics , Plant Proteins*/metabolism , Heat-Shock Response*/genetics , Heat Shock Transcription Factors*/genetics , Heat Shock Transcription Factors*/metabolism , Thermotolerance*/genetics , Transcription, Genetic*, Gene Expression Regulation, Plant ; Arabidopsis/genetics ; Plants, Genetically Modified ; Promoter Regions, Genetic ; Transcription Factors/genetics ; Transcription Factors/metabolism

SFPQ-TFE3 reciprocally regulates mTORC1 and induces lineage plasticity in a mouse model of renal tumorigenesis.

Autori: Asrani K Amaral A Woo J a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Oct 03; Vol. 16 (1), pp. 8822. Date of Electronic Publication: 2025 Oct 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mechanistic Target of Rapamycin Complex 1*/metabolism , Mechanistic Target of Rapamycin Complex 1*/genetics , Kidney Neoplasms*/genetics , Kidney Neoplasms*/pathology , Kidney Neoplasms*/metabolism , Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/genetics , Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/metabolism , PTB-Associated Splicing Factor*/genetics , PTB-Associated Splicing Factor*/metabolism , Carcinogenesis*/genetics , Carcinogenesis*/pathology , Carcinogenesis*/metabolism , Oncogene Proteins, Fusion*/genetics , Oncogene Proteins, Fusion*/metabolism, Animals ; Humans ; Mice ; Mice, Transgenic ; Disease Models, Animal ; Kidney/pathology ; Kidney/metabolism ; PAX8 Transcription Factor/metabolism ; PAX8 Transcription Factor/genetics ; Cell Lineage/genetics ; Gene Expression Regulation, Neoplastic ; PAX2 Transcription Factor/metabolism ; PAX2 Transcription Factor/genetics ; Cell Line, Tumor

STAT3 inhibitors combined with retinol binding protein 4 complex ameliorate DEN-induced liver carcinogenesis in mice and induce apoptosis via GRP78/ATF6/CHOP signaling pathway.

Autori: Wu D Dong J Li X a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108907. Date of Electronic Publication: 2025 Aug 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: STAT3 Transcription Factor*/antagonists & inhibitors , STAT3 Transcription Factor*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Retinol-Binding Proteins, Plasma*/pharmacology , Retinol-Binding Proteins, Plasma*/chemistry , Liver Neoplasms*/drug therapy , Liver Neoplasms*/chemically induced , Liver Neoplasms*/metabolism , Liver Neoplasms*/pathology, Animals ; Apoptosis/drug effects ; Endoplasmic Reticulum Chaperone BiP/metabolism ; Mice ; Humans ; Signal Transduction/drug effects ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Diethylnitrosamine ; Molecular Structure ; Transcription Factor CHOP/metabolism ; Structure-Activity Relationship ; Dose-Response Relationship, Drug ; Male ; Molecular Docking Simulation ; Heat-Shock Proteins/metabolism ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/chemically induced ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Activating Transcription Factor 6

Transcription factors ERF74/77/108/125 enhance thermotolerance in rice by regulating common and distinct heat-responsive gene expression.

Autori: Luo A Yang C Yao ZW a ďalší

Zdroj: Plant biotechnology journal [Plant Biotechnol J] 2025 Oct; Vol. 23 (10), pp. 4539-4551. Date of Electronic Publication: 2025 Jul 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley on behalf of the Society for Experimental Biology, Association of Applied Biologists Country of Publication: England NLM ID: 101201889 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-7652 (Electronic) Linking ISSN: 14677644 NLM ISO Abbreviation: Plant Biotechnol J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Oryza*/genetics , Oryza*/physiology , Oryza*/metabolism , Gene Expression Regulation, Plant*/genetics , Thermotolerance*/genetics , Plant Proteins*/metabolism , Plant Proteins*/genetics , Transcription Factors*/metabolism , Transcription Factors*/genetics, Heat-Shock Response/genetics ; Plants, Genetically Modified ; Hot Temperature ; Heat Shock Transcription Factors/genetics ; Heat Shock Transcription Factors/metabolism ; Promoter Regions, Genetic

Pleiotropic function of Dlx5/6 in the development of mammalian vocal and auditory organs.

Autori: Sánchez-Garrido F Bouzerand V Kaiser M a ďalší

Zdroj: PloS one [PLoS One] 2025 Dec 02; Vol. 20 (12), pp. e0337426. Date of Electronic Publication: 2025 Dec 02 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Výrazy zo slovníka MeSH: Homeodomain Proteins*/genetics , Homeodomain Proteins*/metabolism , Vocalization, Animal*/physiology , Transcription Factors*/genetics , Transcription Factors*/metabolism , Ear*/embryology, Animals ; Mice ; Signal Transduction ; SOXE Transcription Factors/metabolism ; SOXE Transcription Factors/genetics ; Gene Expression Regulation, Developmental ; Morphogenesis

Water shortage reduces PHYTOCHROME INTERACTING FACTOR 4, 5 and 3 expression and shade avoidance in Arabidopsis.

Autori: Semmoloni M Costigliolo Rojas C Escudero C a ďalší

Zdroj: The Plant journal : for cell and molecular biology [Plant J] 2025 Dec; Vol. 124 (5), pp. e70610.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Blackwell Scientific Publishers and BIOS Scientific Publishers in association with the Society for Experimental Biology Country of Publication: England NLM ID: 9207397 Publication Model: Print Cited Medium: Internet ISSN: 1365-313X (Electronic) Linking ISSN: 09607412 NLM ISO Abbreviation: Plant J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Arabidopsis*/genetics , Arabidopsis*/physiology , Arabidopsis*/metabolism , Arabidopsis*/growth & development , Arabidopsis*/radiation effects , Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , Basic Helix-Loop-Helix Transcription Factors*/metabolism , Basic Helix-Loop-Helix Transcription Factors*/genetics , Water*/metabolism, Gene Expression Regulation, Plant ; Hypocotyl/growth & development ; Hypocotyl/genetics ; Hypocotyl/metabolism ; Hypocotyl/physiology ; Hypocotyl/radiation effects ; Seedlings/genetics ; Seedlings/growth & development ; Seedlings/physiology ; Light ; Promoter Regions, Genetic ; Indoleacetic Acids/metabolism ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Signal Transduction

The SWI/SNF complex mediated chromatin remodeling promotes hepatitis B virus cccDNA transcription.

Autori: Yuan X Geng W Wang J a ďalší

Zdroj: Science China. Life sciences [Sci China Life Sci] 2025 Dec; Vol. 68 (12), pp. 3486-3494. Date of Electronic Publication: 2025 Nov 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Science China Press, co-published with Springer Country of Publication: China NLM ID: 101529880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1869-1889 (Electronic) Linking ISSN: 16747305 NLM ISO Abbreviation: Sci China Life Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Hepatitis B virus*/genetics , Hepatitis B virus*/physiology , Chromatin Assembly and Disassembly*/genetics , Transcription Factors*/metabolism , Transcription Factors*/genetics , DNA, Circular*/genetics , DNA, Circular*/metabolism , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics , DNA, Viral*/genetics , DNA, Viral*/metabolism , Viral Transcription*, Humans ; DNA Helicases/metabolism ; DNA Helicases/genetics ; Nuclear Proteins/metabolism ; Nuclear Proteins/genetics ; Virus Replication/genetics ; Hep G2 Cells ; Viral Regulatory and Accessory Proteins/metabolism ; Trans-Activators/metabolism ; Hepatocytes/virology ; Hepatocytes/metabolism ; Chromatin/metabolism ; Transcription, Genetic ; Bromodomain Containing Proteins

Nuclear lamina phase separation orchestrates stress-induced transcriptional responses in plants.

Autori: Tang Y Liu X Fang Y a ďalší

Zdroj: Developmental cell [Dev Cell] 2025 Dec 01; Vol. 60 (23), pp. 3156-3166.e8. Date of Electronic Publication: 2025 Aug 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

Výrazy zo slovníka MeSH: Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , Arabidopsis*/genetics , Arabidopsis*/metabolism , Gene Expression Regulation, Plant* , Stress, Physiological*/genetics , Nuclear Lamina*/metabolism , Nuclear Lamina*/genetics , Transcription, Genetic*, Transcription Factors/metabolism ; Transcription Factors/genetics ; Heat-Shock Response ; Membrane Proteins/metabolism ; Membrane Proteins/genetics ; Phase Separation

Depalmitoylation of TEAD1 facilitates lipid droplet accumulation and resistance to oxidative stress by transactivating PP2Acα.

Autori: Sun X Xu S Ni Y a ďalší

Zdroj: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 01; Vol. 240, pp. 532-545. Date of Electronic Publication: 2025 Aug 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Transcription Factors*/genetics , Transcription Factors*/metabolism , DNA-Binding Proteins*/genetics , DNA-Binding Proteins*/metabolism , Lipid Droplets*/metabolism , Lipid Droplets*/drug effects , Protein Phosphatase 2*/genetics , Protein Phosphatase 2*/metabolism , Chemical and Drug Induced Liver Injury*/metabolism , Chemical and Drug Induced Liver Injury*/pathology , Chemical and Drug Induced Liver Injury*/genetics , Nuclear Proteins*/genetics , Nuclear Proteins*/metabolism, Animals ; Mice ; TEA Domain Transcription Factors ; Oxidative Stress/drug effects ; Mice, Knockout ; Acetaminophen/toxicity ; Acetaminophen/adverse effects ; Hepatocytes/metabolism ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Liver/metabolism ; Liver/pathology ; Liver/drug effects ; Humans ; Lipid Metabolism ; Male ; Transcriptional Activation ; Signal Transduction ; Reactive Oxygen Species/metabolism

Post-replicative initial expression of PAX6 during neuroectoderm differentiation.

Autori: Hu S Kou R Su Z a ďalší

Zdroj: The EMBO journal [EMBO J] 2025 Dec; Vol. 44 (23), pp. 7090-7118. Date of Electronic Publication: 2025 Oct 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Repressor Proteins*/genetics , Repressor Proteins*/metabolism , Repressor Proteins*/biosynthesis , Cell Differentiation* , Eye Proteins*/genetics , Eye Proteins*/metabolism , Eye Proteins*/biosynthesis , Paired Box Transcription Factors*/genetics , Paired Box Transcription Factors*/metabolism , Paired Box Transcription Factors*/biosynthesis , Homeodomain Proteins*/genetics , Homeodomain Proteins*/metabolism , Homeodomain Proteins*/biosynthesis , Neural Plate*/cytology , Neural Plate*/metabolism , Gene Expression Regulation, Developmental*, PAX6 Transcription Factor ; Humans ; Promoter Regions, Genetic ; Neural Stem Cells/cytology ; Neural Stem Cells/metabolism ; G2 Phase ; Human Embryonic Stem Cells/cytology ; Human Embryonic Stem Cells/metabolism ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/metabolism