Suchergebnisse - "Tissue Inhibitor of Metalloproteinase-1"

The ferroptosis-associated gene TIMP1 facilitates skin scar formation through the interaction with CST3 in fibroblasts.

Autoren: He J Li L Xiong D et al.

Quelle: International immunopharmacology [Int Immunopharmacol] 2025 Nov 14; Vol. 165, pp. 115496. Date of Electronic Publication: 2025 Sep 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Fibroblasts*/metabolism , Cicatrix*/genetics , Cicatrix*/pathology , Cicatrix*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/genetics , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Ferroptosis*/genetics , Skin*/pathology , Skin*/metabolism, Humans ; Macrophages/metabolism ; Cells, Cultured ; Cell Differentiation ; Wound Healing ; Cell Communication

Expression levels of MMP-1, MMP-3, and TIMP-1 in pediatric tonsillar tissue: A comparative study of tonsillar hypertrophy and chronic tonsillitis.

Autoren: Karabiber Cicek S Acar G Bingul I et al.

Quelle: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2025 Nov; Vol. 198, pp. 112573. Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8003603 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8464 (Electronic) Linking ISSN: 01655876 NLM ISO Abbreviation: Int J Pediatr Otorhinolaryngol Subsets: MEDLINE

MeSH-Schlagworte: Tonsillitis*/metabolism , Tonsillitis*/surgery , Tonsillitis*/pathology , Palatine Tonsil*/pathology , Palatine Tonsil*/metabolism , Matrix Metalloproteinase 3*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Matrix Metalloproteinase 1*/metabolism, Humans ; Hypertrophy/pathology ; Hypertrophy/metabolism ; Child ; Male ; Female ; Chronic Disease ; Child, Preschool ; Adolescent ; Biomarkers/metabolism ; Tonsillectomy ; Enzyme-Linked Immunosorbent Assay

TIMP1: A novel immune-related signature associated with invasiveness and inhibition of pituitary adenoma.

Autoren: Wu H Zhang Y Ma X et al.

Quelle: Genomics [Genomics] 2025 Nov; Vol. 117 (6), pp. 111140. Date of Electronic Publication: 2025 Oct 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 8800135 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8646 (Electronic) Linking ISSN: 08887543 NLM ISO Abbreviation: Genomics Subsets: MEDLINE

MeSH-Schlagworte: Tissue Inhibitor of Metalloproteinase-1*/genetics , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Pituitary Neoplasms*/genetics , Pituitary Neoplasms*/immunology , Pituitary Neoplasms*/pathology , Pituitary Neoplasms*/metabolism , Adenoma*/genetics , Adenoma*/immunology , Adenoma*/pathology , Adenoma*/metabolism, Humans ; Neoplasm Invasiveness ; Cell Line, Tumor ; Tumor Microenvironment ; Cell Proliferation ; Cell Movement ; Transcriptome ; Gene Expression Regulation, Neoplastic

Multi-Omics Dissection of TIMP1 in Monocytes/Macrophages Reveals Pathogenic Mechanisms and Therapeutic Opportunities in Ankylosing Spondylitis.

Autoren: Chen J Huang C Xue J et al.

Quelle: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Oct 31; Vol. 39 (20), pp. e71086.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

MeSH-Schlagworte: Tissue Inhibitor of Metalloproteinase-1*/genetics , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Monocytes*/metabolism , Monocytes*/pathology , Spondylitis, Ankylosing*/metabolism , Spondylitis, Ankylosing*/drug therapy , Spondylitis, Ankylosing*/genetics , Spondylitis, Ankylosing*/pathology , Macrophages*/metabolism , Macrophages*/pathology, Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Animals ; Proteomics/methods ; Male ; STAT1 Transcription Factor/metabolism ; STAT1 Transcription Factor/genetics ; Multiomics

Early plasma changes of HIF-1 alpha, matrix metalloproteinases-2 and - 9, and tissue inhibitor of matrix metalloproteinase-1 in patients with infantile hemangiomas treated with propranolol.

Autoren: Kowalska M Koper-Lenkiewicz OM Kamińska J et al.

Quelle: Pharmacological reports : PR [Pharmacol Rep] 2025 Oct; Vol. 77 (5), pp. 1364-1373. Date of Electronic Publication: 2025 Jul 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101234999 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2299-5684 (Electronic) Linking ISSN: 17341140 NLM ISO Abbreviation: Pharmacol Rep Subsets: MEDLINE

MeSH-Schlagworte: Propranolol*/therapeutic use , Propranolol*/pharmacology , Matrix Metalloproteinase 2*/blood , Hypoxia-Inducible Factor 1, alpha Subunit*/blood , Matrix Metalloproteinase 9*/blood , Tissue Inhibitor of Metalloproteinase-1*/blood , Hemangioma*/drug therapy , Hemangioma*/blood , Adrenergic beta-Antagonists*/therapeutic use , Adrenergic beta-Antagonists*/pharmacology, Humans ; Male ; Female ; Infant ; Case-Control Studies

Functional analysis of secreted tissue inhibitor of metalloproteinases-1 from adult human neural stem cells (ahNSCs) for regeneration and neuroprotection.

Autoren: Kim KH Hong DG Chae HY et al.

Quelle: BMB reports [BMB Rep] 2025 Oct; Vol. 58 (10), pp. 444-449.

Publikationsart: Journal Article; News

Info zur Zeitschrift: Publisher: Korean Society for Biochemistry and Molecular Biology Country of Publication: Korea (South) NLM ID: 101465334 Publication Model: Print Cited Medium: Internet ISSN: 1976-670X (Electronic) Linking ISSN: 19766696 NLM ISO Abbreviation: BMB Rep Subsets: MEDLINE

MeSH-Schlagworte: Neural Stem Cells*/metabolism , Neural Stem Cells*/cytology , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Neuroprotection*/physiology , Regeneration*/physiology , Adult Stem Cells*/metabolism, Humans ; Culture Media, Conditioned/pharmacology ; Chemokine CCL2/metabolism ; Apoptosis/drug effects ; Glucose/deficiency ; Wound Healing/drug effects ; Neurons/metabolism ; Cells, Cultured

TIMP1 inhibits Rac1-mediated ROS production to ameliorate blood-spinal cord barrier disruption in amyotrophic lateral sclerosis.

Autoren: Tang J Kang Y Chen Q et al.

Quelle: Neurobiology of disease [Neurobiol Dis] 2025 Sep; Vol. 213, pp. 106987. Date of Electronic Publication: 2025 Jun 10.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

MeSH-Schlagworte: Amyotrophic Lateral Sclerosis*/metabolism , Amyotrophic Lateral Sclerosis*/pathology , rac1 GTP-Binding Protein*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/genetics , Spinal Cord*/metabolism , Spinal Cord*/pathology , Reactive Oxygen Species*/metabolism, Animals ; Mice ; Endothelial Cells/metabolism ; Mice, Transgenic ; Humans ; Mice, Inbred C57BL ; Male ; Neuropeptides

Zhuling Yanzong formula ameliorates obesity-induced oligoasthenozoospermia via regulating HSL/StAR and HSL/TIMP-1.

Autoren: Pan M Zhao H Xu F et al.

Quelle: Journal of ethnopharmacology [J Ethnopharmacol] 2025 Sep 25; Vol. 353 (Pt A), pp. 120319. Date of Electronic Publication: 2025 Jul 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/therapeutic use , Obesity*/complications , Obesity*/drug therapy , Oligospermia*/drug therapy , Oligospermia*/etiology , Oligospermia*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/genetics , Asthenozoospermia*/drug therapy , Asthenozoospermia*/etiology, Male ; Animals ; Mice ; Mice, Inbred C57BL ; Testis/drug effects ; Testis/metabolism ; Diet, High-Fat

Dibutyl phthalate promotes COAD cells growth and migration via the TIMP1/PI3K/AKT signaling axis.

Autoren: Huang Q Chen X Ge X et al.

Quelle: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2025 Sep 15; Vol. 303, pp. 118931. Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2414 (Electronic) Linking ISSN: 01476513 NLM ISO Abbreviation: Ecotoxicol Environ Saf Subsets: MEDLINE

MeSH-Schlagworte: Dibutyl Phthalate*/toxicity , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/genetics , Colonic Neoplasms*/chemically induced , Plasticizers*/toxicity , Adenocarcinoma*/chemically induced, Humans ; Cell Proliferation/drug effects ; Signal Transduction/drug effects ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Cell Movement/drug effects ; HT29 Cells ; Caco-2 Cells

Association between BRAFV600E mutation and gene expression of CLDN1, TIMP1, and KRT19 in papillary thyroid cancer.

Autoren: Ross-Orozco A Gastelum-Quiroz AR Alvarez-Arrazola M et al.

Quelle: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2025 Sep 15; Vol. 607, pp. 112614. Date of Electronic Publication: 2025 Jul 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: North Holland Publishing Country of Publication: Ireland NLM ID: 7500844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8057 (Electronic) Linking ISSN: 03037207 NLM ISO Abbreviation: Mol Cell Endocrinol Subsets: MEDLINE

MeSH-Schlagworte: Proto-Oncogene Proteins B-raf*/genetics , Thyroid Cancer, Papillary*/genetics , Thyroid Cancer, Papillary*/pathology , Tissue Inhibitor of Metalloproteinase-1*/genetics , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Thyroid Neoplasms*/genetics , Thyroid Neoplasms*/pathology , Gene Expression Regulation, Neoplastic* , Claudin-1*/genetics , Claudin-1*/metabolism , Mutation*/genetics , Keratin-19*/genetics , Keratin-19*/metabolism, Humans ; Female ; Male ; Middle Aged ; Adult ; Aged ; Genetic Association Studies

TIMP-1 Modulation Correlates with KRAS Dependency and EMT Induction in NSCLC.

Autoren: M-Thirusenthilarasan I Ahluwalia P Thorenoor N et al.

Quelle: Cells [Cells] 2025 Sep 10; Vol. 14 (18). Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH-Schlagworte: Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/metabolism , Proto-Oncogene Proteins p21(ras)*/metabolism , Proto-Oncogene Proteins p21(ras)*/genetics , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Epithelial-Mesenchymal Transition*/genetics, Humans ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Apoptosis/genetics

Single-nucleus RNA sequencing reveals HBV-driven metabolic reprogramming and TIMP1-mediated fibrosis in human-liver-chimeric mice.

Autoren: Ren X Wang C Qin B et al.

Quelle: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2025 Sep 02; Vol. 15, pp. 1654903. Date of Electronic Publication: 2025 Sep 02 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

MeSH-Schlagworte: Tissue Inhibitor of Metalloproteinase-1*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/genetics , Hepatitis B virus*/genetics , Liver Cirrhosis*/virology , Liver Cirrhosis*/metabolism , Liver Cirrhosis*/pathology , Liver Cirrhosis*/genetics , Hepatitis B, Chronic*/virology , Hepatitis B, Chronic*/metabolism , Hepatitis B, Chronic*/pathology, Animals ; Humans ; Mice ; Hepatocytes/virology ; Hepatocytes/metabolism ; Liver/virology ; Liver/pathology ; Liver/metabolism ; Disease Models, Animal ; Sequence Analysis, RNA ; Hepatitis B Surface Antigens/blood ; DNA, Viral/blood ; Metabolic Reprogramming

A secreted signature discriminates indolent from aggressive prostate tumors.

Autoren: Wang Y Liu Y Lin X et al.

Quelle: World journal of urology [World J Urol] 2025 Aug 21; Vol. 43 (1), pp. 506. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Country of Publication: Germany NLM ID: 8307716 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-8726 (Electronic) Linking ISSN: 07244983 NLM ISO Abbreviation: World J Urol Subsets: MEDLINE

MeSH-Schlagworte: Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/diagnosis , Prostatic Neoplasms*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/genetics , Tissue Inhibitor of Metalloproteinase-1*/metabolism, Male ; Humans ; Animals ; Mice ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Neoplasm Invasiveness ; Macrophages ; Diagnosis, Differential ; Membrane Proteins/genetics ; Membrane Proteins/metabolism

TIMP-1 enhances Akt and BDNF signaling in neurons to reduce synaptic and cognitive deficits in 5xFAD mouse model of Alzheimer's disease.

Autoren: Sarkar S Gharami K Mondal A et al.

Quelle: Acta neuropathologica communications [Acta Neuropathol Commun] 2025 Aug 19; Vol. 13 (1), pp. 178. Date of Electronic Publication: 2025 Aug 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/metabolism , Alzheimer Disease*/pathology , Alzheimer Disease*/genetics , Alzheimer Disease*/complications , Brain-Derived Neurotrophic Factor*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/pharmacology , Neurons*/metabolism , Neurons*/pathology , Neurons*/drug effects , Proto-Oncogene Proteins c-akt*/metabolism , Synapses*/metabolism , Synapses*/pathology , Cognitive Dysfunction*/metabolism, Animals ; Mice, Transgenic ; Disease Models, Animal ; Signal Transduction/physiology ; Signal Transduction/drug effects ; Mice ; Hippocampus/metabolism ; Hippocampus/pathology ; Humans ; Male ; Mice, Inbred C57BL ; Amyloid beta-Protein Precursor/genetics

The inhibitory effect of M2 macrophage-derived exosomes on gefitinib resistant lung adenocarcinoma cells through the MIF/TIMP1/CD74 axis.

Autoren: Peng J Zhang Y Li B et al.

Quelle: Scientific reports [Sci Rep] 2025 Aug 05; Vol. 15 (1), pp. 28482. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Exosomes*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/genetics , Macrophage Migration-Inhibitory Factors*/metabolism , Adenocarcinoma of Lung*/drug therapy , Adenocarcinoma of Lung*/metabolism , Adenocarcinoma of Lung*/pathology , Adenocarcinoma of Lung*/genetics , Gefitinib*/pharmacology , Drug Resistance, Neoplasm* , Antigens, Differentiation, B-Lymphocyte*/metabolism , Antigens, Differentiation, B-Lymphocyte*/genetics , Macrophages*/metabolism , Lung Neoplasms*/metabolism , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Histocompatibility Antigens Class II*/metabolism , Histocompatibility Antigens Class II*/genetics , Intramolecular Oxidoreductases*/metabolism, Humans ; Cell Line, Tumor ; Signal Transduction/drug effects ; Cell Proliferation/drug effects ; Antineoplastic Agents/pharmacology

TIMP1 promotes microglia M2 polarization through MAPK pathway to ameliorate early brain injury after ischemia.

Autoren: Zhao K Huang Z

Quelle: Hereditas [Hereditas] 2025 Jul 02; Vol. 162 (1), pp. 119. Date of Electronic Publication: 2025 Jul 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 0374654 Publication Model: Electronic Cited Medium: Internet ISSN: 1601-5223 (Electronic) Linking ISSN: 00180661 NLM ISO Abbreviation: Hereditas Subsets: MEDLINE

MeSH-Schlagworte: Tissue Inhibitor of Metalloproteinase-1*/genetics , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Microglia*/metabolism , MAP Kinase Signaling System* , Brain Ischemia*/genetics , Brain Injuries*/genetics , Brain Injuries*/etiology , Brain Injuries*/metabolism, Animals ; Mice ; Male ; Disease Models, Animal ; Cell Line ; Apoptosis ; Vimentin/genetics ; Vimentin/metabolism ; Rats

The role of serum levels of matrix metalloproteinases and their inhibitors in the etiology of inguinal hernia.

Autoren: Basoglu H Yanar F Sengun B et al.

Quelle: Hernia : the journal of hernias and abdominal wall surgery [Hernia] 2025 Sep 23; Vol. 29 (1), pp. 280. Date of Electronic Publication: 2025 Sep 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: France NLM ID: 9715168 Publication Model: Electronic Cited Medium: Internet ISSN: 1248-9204 (Electronic) Linking ISSN: 12489204 NLM ISO Abbreviation: Hernia Subsets: MEDLINE

MeSH-Schlagworte: Hernia, Inguinal*/blood , Hernia, Inguinal*/etiology , Matrix Metalloproteinases*/blood , Tissue Inhibitor of Metalloproteinase-1*/blood, Humans ; Male ; Middle Aged ; Adult ; Tissue Inhibitor of Metalloproteinase-2/blood ; Aged ; Case-Control Studies ; Matrix Metalloproteinase 8/blood ; Matrix Metalloproteinase 1/blood

Vitreous MMP-2, TIMP-1, and TIMP-2 Levels in Vitreoretinal Pathologies: A Prospective Analysis of 181 Eyes.

Autoren: Al-Dwairi R El-Elimat T Aleshawi A et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 14; Vol. 26 (18). Date of Electronic Publication: 2025 Sep 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Tissue Inhibitor of Metalloproteinase-2*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Matrix Metalloproteinase 2*/metabolism , Vitreous Body*/metabolism , Vitreous Body*/pathology , Retinal Diseases*/metabolism, Humans ; Female ; Male ; Middle Aged ; Prospective Studies ; Aged ; Vitrectomy ; Retinal Detachment/metabolism ; Retinal Detachment/surgery ; Retinal Detachment/pathology ; Diabetic Retinopathy/metabolism ; Diabetic Retinopathy/surgery ; Diabetic Retinopathy/pathology ; Adult ; Biomarkers/metabolism

Comparison of microcurrent and low level laser therapy on matrix metalloproteinases and tissue inhibitors of metalloproteinases expressions in surgical wound healing.

Autoren: El Makakey AM Hassan MH Abo-Zaid NA et al.

Quelle: Scientific reports [Sci Rep] 2025 Aug 12; Vol. 15 (1), pp. 29600. Date of Electronic Publication: 2025 Aug 12.

Publikationsart: Journal Article; Comparative Study; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Low-Level Light Therapy*/methods , Matrix Metalloproteinase 8*/metabolism , Matrix Metalloproteinase 9*/metabolism , Surgical Wound*/therapy , Surgical Wound*/metabolism , Surgical Wound*/radiotherapy , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Wound Healing*/radiation effects, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult

EZH2-mediated suppression of TIMP1 in spinal GABAergic interneurons drives microglial activation via MMP-9-TLR2/4-NLRP3 signaling in neuropathic pain.

Autoren: Wan L Guo H Hu F et al.

Quelle: Brain, behavior, and immunity [Brain Behav Immun] 2025 Aug; Vol. 128, pp. 234-255. Date of Electronic Publication: 2025 Apr 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

MeSH-Schlagworte: Neuralgia*/metabolism , Tissue Inhibitor of Metalloproteinase-1*/metabolism , Enhancer of Zeste Homolog 2 Protein*/metabolism, Animals ; Matrix Metalloproteinase 9/metabolism ; Mice ; Microglia/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Toll-Like Receptor 4/metabolism ; Male ; Signal Transduction/drug effects ; Toll-Like Receptor 2/metabolism ; Rats ; Spinal Cord/metabolism ; Interneurons/metabolism ; GABAergic Neurons/metabolism ; Rats, Sprague-Dawley ; Mice, Inbred C57BL ; Hyperalgesia/metabolism ; Humans