Suchergebnisse - "Teumer, Alexander"

Polygenic prediction of body mass index and obesity through the life course and across ancestries

Autoren: Smit, Roelof A J Wade, Kaitlin H. Hui, Qin et al.

Quelle: Nature Medicine. 31(9):3151-3168

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-244710
https://umu.diva-portal.org/smash/get/diva2:2006943/FULLTEXT01.pdf

Associations between common genetic variants and income provide insights about the socio-economic health gradient

Autoren: Kwong, Alex S F Lee, James J Luik, Annemarie I et al.

Quelle: Nature Human Behaviour. 9:794-805

Schlagwörter: 10 Reduced inequalities, 03 Good Health and Well-being

Dateibeschreibung: electronic

Zugangs-URL: https://research.hhs.se/esploro/outputs/journalArticle/Associations-between-common-genetic-variants-and/991001625799406056
https://research.hhs.se/esploro/outputs/journalArticle/Associations-between-common-genetic-variants-and/991001625799406056

Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.

Autoren: Henry, Albert Mo, Xiaodong Finan, Chris et al.

Quelle: Nature Genetics. 57(4):815-828

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:du-50331
https://doi.org/10.1038/s41588-024-02064-3

Beyond the global brain differences: intraindividual variability differences in 1q21.1 distal and 15q11.2 bp1-bp2 deletion carriers

Autoren: Boen, Rune Kaufmann, Tobias van der Meer, Dennis et al.

Quelle: Biological Psychiatry. 95(2):147-160

Schlagwörter: 15q11.2 BP1-BP2, 1q21.1 distal, Brain structure, Copy number variants, Intraindividual variability, Magnetic resonance imaging

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-218106
https://doi.org/10.1016/j.biopsych.2023.08.018

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

Autoren: Keaton, Jacob M Kamali, Zoha Xie, Tian et al.

Quelle: Nature Genetics. 56(5):778-791

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-546354
https://doi.org/10.1038/s41588-024-01714-w

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

Autoren: Boomsma, Dorret I Mathieson, Iain Day, Felix R et al.

Quelle: Nature Human Behaviour. 7(5):790-801

Zugangs-URL: https://research.hhs.se/esploro/outputs/journalArticle/Genome-wide-analysis-identifies-genetic-effects-on/991001509199206056

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Autoren: Bakker, Mark K. Kanning, Jos P. Abraham, Gad et al.

Quelle: Stroke. 54(3):810-818

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-546357
https://doi.org/10.1161/STROKEAHA.122.040715

Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration

Autoren: Groeneweg, Stefan van Geest, Ferdy S Martín, Mariano et al.

Quelle: Nature Communications. 16(1)

Schlagwörter: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Rare Diseases, Clinical Research, Human Genome, Machine Learning and Artificial Intelligence, 2.1 Biological and endogenous factors, 4.1 Discovery and preclinical testing of markers and technologies, 2.4 Surveillance and distribution, Good Health and Well Being, Humans, Monocarboxylic Acid Transporters, Deep Learning, Male, Symporters, Phenotype, X-Linked Intellectual Disability, Female, Muscular Atrophy, Muscle Hypotonia, Thyroid Hormones, Loss of Function Mutation, Genomics

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/5cx2d4hr
https://escholarship.org/content/qt5cx2d4hr/qt5cx2d4hr.pdf

Using Two-Sample Mendelian Randomization to Identify Potential Drug Targets: The Case of Desmoplakin

Autoren: Foco , Luisa De Bortoli , Marzia Del Greco, M Fabiola et al.

Quelle: Epidemiology, Biostatistics, and Public Health.

A saturated map of common genetic variants associated with human height

Autoren: Yengo, Loïc Vedantam, Sailaja Marouli, Eirini et al.

Quelle: Nature. 610(7933):704-712

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-200546
https://doi.org/10.1038/s41586-022-05275-y

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

Autoren: Gorski, Mathias Rasheed, Humaira Teumer, Alexander et al.

Quelle: Kidney International. 102(3):624-639

Schlagwörter: acute kidney injury, chronic kidney disease, diabetes, gene expression

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:du-41692
https://doi.org/10.1016/j.kint.2022.05.021

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

Autoren: Wang, Zhe Emmerich, Andrew Pillon, Nicolas J et al.

Quelle: Nature Genetics. 54(9):1332-1344

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489990
https://doi.org/10.1038/s41588-022-01165-1

Genome-wide association study of circulating interleukin 6 levels identifies novel loci

Autoren: Ahluwalia, Tarunveer S. Prins, Bram P. Abdollahi, Mohammadreza et al.

Quelle: Human Molecular Genetics. 30(5):393-409

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-445822
https://doi.org/10.1093/hmg/ddab023

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

Autoren: Gorski, Mathias Jung, Bettina Li, Yong et al.

Quelle: Kidney International. 99(4):926-939

Schlagwörter: Genome-wide association study, acute kidney injury, end-stage kidney disease, rapid eGFRcrea decline

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-430992
https://doi.org/10.1016/j.kint.2020.09.030

Distinct genetic liability profiles define clinically relevant patient strata across common diseases.

Autoren: Trastulla, Lucia Dolgalev, Georgii Moser, Sylvain et al.

Quelle: Nature Communications. 15(1)

Schlagwörter: Humans, Schizophrenia, Multifactorial Inheritance, Genetic Predisposition to Disease, Coronary Artery Disease, Risk Factors, Female, Precision Medicine, Male, Genome-Wide Association Study, Middle Aged, Polymorphism, Single Nucleotide

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/8sm5d1xw
https://escholarship.org/content/qt8sm5d1xw/qt8sm5d1xw.pdf

Thyroid Function, Diabetes, and Common Age-Related Eye Diseases: A Mendelian Randomization Study: A Mendelian Randomization Study

Autoren: Ellervik, Christina Boulakh, Lena Teumer, Alexander et al.

Quelle: Thyroid, 34, 11, pp. 1414-1423
The International AMD Genomics Consortium, and The Mendelian Randomization Study Group for the ThyroidOmics Consortium 2024, 'Thyroid Function, Diabetes, and Common Age-Related Eye Diseases : A Mendelian Randomization Study', Thyroid, vol. 34, no. 11, pp. 1414-1423. https://doi.org/10.1089/thy.2024.0257

Schlagwörter: Male, Thyroid Gland, Thyrotropin, Hyperthyroidism, Polymorphism, Single Nucleotide, Cataract, Macular Degeneration, SDG 3 - Good Health and Well-being, Hypothyroidism, Risk Factors, Humans, Internal Medicine - Radboud University Medical Center, Aged, age-related macular degeneration (AMD), Diabetic Retinopathy, thyroid function, Mendelian Randomization Analysis, diabetic retinopathy, Thyroxine, glaucoma, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, cataract, Female, autoimmune thyroid disease, Glaucoma, Open-Angle, Genome-Wide Association Study

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39283829
https://repository.ubn.ru.nl//bitstream/handle/2066/313923/313923.pdf
https://hdl.handle.net/2066/313923

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Autoren: Ehret, Georg B Ferreira, Teresa Chasman, Daniel I et al.

Schlagwörter: Genome-wide association studies, Hypertension

Verfügbarkeit: http://hdl.handle.net/10150/623255
http://arizona.openrepository.com/arizona/handle/10150/623255

Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

Autoren: Sonderby, Ida E. Gustafsson, Omar Doan, Nhat Trung et al.

Quelle: Molecular Psychiatry. 25(3):584-602

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-169456
https://doi.org/10.1038/s41380-018-0118-1

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

Autoren: Yaghootkar, Hanieh Zhang, Yiying Spracklen, Cassandra N. et al.

Quelle: Diabetes. 69(12):2806-2818

Schlagwörter: Medicinsk teknik, Medical Engineering

Dateibeschreibung: print

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-82754
https://doi.org/10.2337/db20-0070

OTTERS: a powerful TWAS framework leveraging summary-level reference data

Autoren: Dai, Qile Zhou, Geyu Zhao, Hongyu et al.

Quelle: Nature Communications. 14(1)

Schlagwörter: Medicinsk teknik, Medical Engineering

Dateibeschreibung: electronic

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-96339
https://doi.org/10.1038/s41467-023-36862-w