Suchergebnisse - "Tears"

Tear matrix metalloproteinase 9 immunoassay positivity reflects the severity of conjunctivochalasis.

Autoren: Lee J Bang SP Shim KY et al.

Quelle: Scientific reports [Sci Rep] 2025 Oct 13; Vol. 15 (1), pp. 35591. Date of Electronic Publication: 2025 Oct 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Matrix Metalloproteinase 9*/metabolism , Matrix Metalloproteinase 9*/analysis , Tears*/enzymology , Tears*/metabolism , Conjunctival Diseases*/diagnosis , Conjunctival Diseases*/metabolism , Conjunctival Diseases*/enzymology, Humans ; Female ; Male ; Middle Aged ; Severity of Illness Index ; Prospective Studies ; Adult ; Aged ; Immunoassay/methods ; Dry Eye Syndromes/diagnosis ; Biomarkers/metabolism ; Case-Control Studies

Comparative glycomic analysis of hawk ( Rupornis magnirostris ), caiman ( Caiman latirostris ) and sea turtle ( Caretta caretta ) tear films.

Autoren: Raposo AC Grijaldo-Alvarez SJB Xu G et al.

Quelle: Molecular omics [Mol Omics] 2025 Dec 01; Vol. 21 (6), pp. 633-644. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101713384 Publication Model: Electronic Cited Medium: Internet ISSN: 2515-4184 (Electronic) Linking ISSN: 25154184 NLM ISO Abbreviation: Mol Omics Subsets: MEDLINE

MeSH-Schlagworte: Turtles*/metabolism , Glycomics*/methods , Tears*/metabolism , Tears*/chemistry , Polysaccharides*/metabolism , Polysaccharides*/analysis , Alligators and Crocodiles*/metabolism, Animals ; Glycoproteins/metabolism ; Solid Phase Extraction

New insights on liposomal formulations based upon tear film lipids: A combined study of safety and ocular surface pharmacokinetics.

Autoren: Jäntti J Puranen J Merivaara A et al.

Quelle: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2025 Dec 01; Vol. 215, pp. 107282. Date of Electronic Publication: 2025 Sep 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

MeSH-Schlagworte: Liposomes* , Tears*/metabolism , Tears*/chemistry , Lipids*/chemistry , Lipids*/pharmacokinetics, Rabbits ; Animals ; Humans ; Epithelium, Corneal/metabolism ; Epithelium, Corneal/drug effects ; Dry Eye Syndromes/drug therapy ; Dry Eye Syndromes/metabolism ; Cornea/metabolism ; Cornea/drug effects ; Male ; Phosphatidylcholines/pharmacokinetics ; Phosphatidylcholines/chemistry ; Phosphatidylcholines/administration & dosage ; Cell Line ; Cell Survival/drug effects ; Female

Proteomic analysis of tear fluid: Comparative short-term effects of scleral lenses and rigid corneal lenses wear in ametropic healthy adults.

Autoren: Zhang Z Zeng L Le Q et al.

Quelle: Contact lens & anterior eye : the journal of the British Contact Lens Association [Cont Lens Anterior Eye] 2025 Dec; Vol. 48 (6), pp. 102507. Date of Electronic Publication: 2025 Sep 11.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9712714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5411 (Electronic) Linking ISSN: 13670484 NLM ISO Abbreviation: Cont Lens Anterior Eye Subsets: MEDLINE

MeSH-Schlagworte: Tears*/metabolism , Tears*/chemistry , Proteomics*/methods , Sclera* , Eye Proteins*/metabolism , Contact Lenses*, Humans ; Male ; Female ; Adult ; Prospective Studies ; Young Adult ; Healthy Volunteers

Tear neuropeptides are associated with clinical symptoms and signs of dry eye patients.

Autoren: Zhang Y Zhang H Zhu X et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2451194. Date of Electronic Publication: 2025 Jan 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Tears*/chemistry , Tears*/metabolism , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/metabolism , Dry Eye Syndromes*/physiopathology , Substance P*/metabolism , Substance P*/analysis , Calcitonin Gene-Related Peptide*/metabolism , Calcitonin Gene-Related Peptide*/analysis , Neuropeptide Y*/metabolism , Neuropeptide Y*/analysis , Neuropeptides*/metabolism, Humans ; Female ; Male ; Middle Aged ; Adult ; Case-Control Studies ; Aged

Identification of a blink frequency threshold for maintaining tear film stability in young adults with dry eye symptoms.

Autoren: Chai Y Cheng M Liu X et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 27; Vol. 15 (1), pp. 42321. Date of Electronic Publication: 2025 Nov 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Blinking*/physiology , Tears*/physiology , Tears*/metabolism , Dry Eye Syndromes*/physiopathology , Dry Eye Syndromes*/metabolism, Humans ; Adult ; Female ; Male ; Young Adult

A mass spectrometry-based strategy allows signature metabolite identification in tear fluid from people with diabetic cataracts.

Autoren: Qi Z Wang M Yan C et al.

Quelle: Nature communications [Nat Commun] 2025 Nov 21; Vol. 16 (1), pp. 10246. Date of Electronic Publication: 2025 Nov 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Cataract*/metabolism , Cataract*/diagnosis , Cataract*/etiology , Tears*/metabolism , Tears*/chemistry , Diabetes Complications*/metabolism , Diabetes Complications*/diagnosis, Humans ; Biomarkers/metabolism ; Male ; Female ; Deoxyglucose/metabolism ; Middle Aged ; Aged ; Oxidative Stress ; Aqueous Humor/metabolism ; Mass Spectrometry/methods ; Metabolomics/methods ; Chromatography, Liquid ; Lens, Crystalline/metabolism ; Lens, Crystalline/pathology ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods ; Glucose

Tear crystallization patterns in dogs with evaporative dry eye disease treated with hyaluronic acid and tacrolimus.

Autoren: Barbosa SF Sebbag L Raposo ACS et al.

Quelle: Veterinary research communications [Vet Res Commun] 2025 Nov 11; Vol. 50 (1), pp. 27. Date of Electronic Publication: 2025 Nov 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Switzerland NLM ID: 8100520 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7446 (Electronic) Linking ISSN: 01657380 NLM ISO Abbreviation: Vet Res Commun Subsets: MEDLINE

MeSH-Schlagworte: Hyaluronic Acid*/therapeutic use , Hyaluronic Acid*/administration & dosage , Dog Diseases*/drug therapy , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/veterinary , Tears*/chemistry , Tears*/drug effects , Tacrolimus*/therapeutic use , Tacrolimus*/administration & dosage , Immunosuppressive Agents*/therapeutic use , Immunosuppressive Agents*/administration & dosage, Animals ; Dogs ; Female ; Male ; Crystallization

High-Throughput Tear Proteomics Reveals Multi-Faceted Signatures of Thyroid Eye Disease.

Autoren: Li R Zhang H Yang L et al.

Quelle: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Nov 03; Vol. 66 (14), pp. 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

MeSH-Schlagworte: Proteomics*/methods , Graves Ophthalmopathy*/metabolism , Graves Ophthalmopathy*/diagnosis , Tears*/metabolism , Tears*/chemistry , Eye Proteins*/metabolism, Humans ; Male ; Female ; Middle Aged ; Biomarkers/metabolism ; Adult ; Aged ; Mass Spectrometry

Tear Film Osmolarity in Horses With Bacterial Conjunctivitis.

Autoren: Saberinia A Ozmaei S Anoushepour A

Quelle: Veterinary medicine and science [Vet Med Sci] 2025 Nov; Vol. 11 (6), pp. e70677.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101678837 Publication Model: Print Cited Medium: Internet ISSN: 2053-1095 (Electronic) Linking ISSN: 20531095 NLM ISO Abbreviation: Vet Med Sci Subsets: MEDLINE

MeSH-Schlagworte: Tears*/chemistry , Tears*/physiology , Horse Diseases*/microbiology , Horse Diseases*/physiopathology , Conjunctivitis, Bacterial*/veterinary , Conjunctivitis, Bacterial*/microbiology , Conjunctivitis, Bacterial*/physiopathology, Animals ; Horses ; Osmolar Concentration ; Male ; Female

Temporal Changes in Tear Film Stability With Four Dry Eye Eyedrops in Healthy Subjects.

Autoren: Suzutani M Maehara H Koh S et al.

Quelle: Eye & contact lens [Eye Contact Lens] 2025 Nov 01; Vol. 51 (11), pp. 512-516. Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101160941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-233X (Electronic) Linking ISSN: 15422321 NLM ISO Abbreviation: Eye Contact Lens Subsets: MEDLINE

MeSH-Schlagworte: Tears*/chemistry , Tears*/metabolism , Tears*/drug effects , Uracil Nucleotides*/administration & dosage , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/metabolism , Polyphosphates*/administration & dosage , Ophthalmic Solutions*/administration & dosage , Lubricant Eye Drops*/administration & dosage, Humans ; Male ; Female ; Adult ; Healthy Volunteers ; Young Adult ; Quinolones/administration & dosage ; Middle Aged ; Alanine/analogs & derivatives

The effect of diquafosol on tear film inflammatory markers in patients with dry eye: A noncomparative, open-label, proof-of-concept study.

Autoren: Tanchuling RV Tan PVC Regalado RNC et al.

Quelle: The Journal of international medical research [J Int Med Res] 2025 Nov; Vol. 53 (11), pp. 3000605251387924. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Sage Publications Country of Publication: England NLM ID: 0346411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-2300 (Electronic) Linking ISSN: 03000605 NLM ISO Abbreviation: J Int Med Res Subsets: MEDLINE

MeSH-Schlagworte: Tears*/metabolism , Tears*/drug effects , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/metabolism , Dry Eye Syndromes*/pathology , Uracil Nucleotides*/administration & dosage , Uracil Nucleotides*/therapeutic use , Polyphosphates*/administration & dosage , Polyphosphates*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Ophthalmic Solutions/administration & dosage ; Ophthalmic Solutions/therapeutic use ; Biomarkers/metabolism ; Aged ; Cytokines/metabolism ; Proof of Concept Study ; Adult ; Inflammation/drug therapy

Deep learning for tear film stability assessment and breakup pattern classification in dry eye diagnosis.

Autoren: Qian H Chang J Yan Y et al.

Quelle: Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) [Ophthalmic Physiol Opt] 2025 Nov; Vol. 45 (7), pp. 1747-1760. Date of Electronic Publication: 2025 Aug 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Publishers Country of Publication: England NLM ID: 8208839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-1313 (Electronic) Linking ISSN: 02755408 NLM ISO Abbreviation: Ophthalmic Physiol Opt Subsets: MEDLINE

MeSH-Schlagworte: Tears*/metabolism , Tears*/chemistry , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/metabolism , Deep Learning* , Diagnostic Techniques, Ophthalmological*, Humans ; Female ; Male ; Adult ; Middle Aged ; Aged

Effects of topical 0.5% tropicamide and 1% atropine on pupil diameter, intraocular pressure, and tear production, in healthy pet rabbits.

Autoren: Cabrero M Guyonnet A Mercado L et al.

Quelle: Veterinary ophthalmology [Vet Ophthalmol] 2025 Nov; Vol. 28 (6), pp. 948-955. Date of Electronic Publication: 2024 Sep 27.

Publikationsart: Journal Article; Randomized Controlled Trial, Veterinary

Info zur Zeitschrift: Publisher: Blackwell Science Country of Publication: England NLM ID: 100887377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-5224 (Electronic) Linking ISSN: 14635216 NLM ISO Abbreviation: Vet Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Atropine*/pharmacology , Atropine*/administration & dosage , Tropicamide*/pharmacology , Tropicamide*/administration & dosage , Intraocular Pressure*/drug effects , Tears*/drug effects , Tears*/metabolism , Pupil*/drug effects , Mydriatics*/pharmacology , Mydriatics*/administration & dosage, Animals ; Rabbits/physiology ; Cross-Over Studies ; Male ; Ophthalmic Solutions/administration & dosage ; Ophthalmic Solutions/pharmacology ; Female ; Prospective Studies ; Administration, Topical

Impact of general anesthesia on feline aqueous tear production and the feline corneal epithelium.

Autoren: Haubrich KN Leis ML Levitt SM et al.

Quelle: Journal of feline medicine and surgery [J Feline Med Surg] 2025 Nov; Vol. 27 (11), pp. 1098612X251386135. Date of Electronic Publication: 2025 Sep 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Sage Country of Publication: England NLM ID: 100897329 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2750 (Electronic) Linking ISSN: 1098612X NLM ISO Abbreviation: J Feline Med Surg Subsets: MEDLINE

MeSH-Schlagworte: Tears*/drug effects , Tears*/physiology , Cat Diseases*/etiology , Cat Diseases*/chemically induced , Cat Diseases*/epidemiology , Anesthesia, General*/veterinary , Anesthesia, General*/adverse effects , Epithelium, Corneal*/drug effects , Corneal Injuries*/veterinary , Corneal Injuries*/etiology, Animals ; Cats ; Female ; Male ; Risk Factors

Confounding factors in the tear break-up time test. Influence of sequential measurements.

Autoren: Acet Y Dağ Y

Quelle: Clinical & experimental optometry [Clin Exp Optom] 2025 Nov; Vol. 108 (8), pp. 966-972. Date of Electronic Publication: 2025 Mar 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8703442 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1444-0938 (Electronic) Linking ISSN: 08164622 NLM ISO Abbreviation: Clin Exp Optom Subsets: MEDLINE

MeSH-Schlagworte: Tears*/metabolism , Tears*/chemistry , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/metabolism, Humans ; Female ; Adult ; Young Adult ; Reproducibility of Results ; Time Factors ; Adolescent

TFOS DEWS III: Diagnostic Methodology.

Autoren: Wolffsohn JS Benítez-Del-Castillo JM Loya-Garcia D et al.

Körperschaften: Wolffsohn JS Benítez-Del-Castillo JM Loya-Garcia D et al.

Quelle: American journal of ophthalmology [Am J Ophthalmol] 2025 Nov; Vol. 279, pp. 387-450. Date of Electronic Publication: 2025 May 30.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/diagnosis , Tears*/physiology , Tears*/chemistry , Diagnostic Techniques, Ophthalmological* , Ophthalmology*/organization & administration , Societies, Medical*, Humans ; Surveys and Questionnaires ; Diagnosis, Differential

Comprehensive lipid analysis of human meibum and tears.

Autoren: Terai M Jojima K Ogawa-Sawai M et al.

Quelle: Scientific reports [Sci Rep] 2025 Oct 30; Vol. 15 (1), pp. 35556. Date of Electronic Publication: 2025 Oct 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Tears*/chemistry , Tears*/metabolism , Meibomian Glands*/chemistry , Meibomian Glands*/metabolism , Lipids*/analysis, Humans ; Female ; Male ; Middle Aged ; Tandem Mass Spectrometry ; Adult ; Cholesterol Esters/analysis ; Chromatography, Liquid ; Sphingomyelins/analysis ; Lipidomics/methods

Comparative Tear Fluid Proteomics to Explore Treatment Responsiveness in Diabetic Macular Edema: A Pilot Study.

Autoren: Ma IH Hsu YL Wu HY et al.

Quelle: Journal of proteome research [J Proteome Res] 2025 Oct 03; Vol. 24 (10), pp. 4925-4934. Date of Electronic Publication: 2025 Aug 29.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

MeSH-Schlagworte: Macular Edema*/drug therapy , Macular Edema*/metabolism , Macular Edema*/pathology , Proteomics*/methods , Tears*/chemistry , Tears*/metabolism , Diabetic Retinopathy*/drug therapy , Diabetic Retinopathy*/metabolism , Diabetic Retinopathy*/pathology , Eye Proteins*/metabolism , Eye Proteins*/genetics , Eye Proteins*/analysis , Proteome*, Humans ; Pilot Projects ; Female ; Male ; Middle Aged ; Aged ; Insulin-Like Growth Factor Binding Protein 3/genetics ; Insulin-Like Growth Factor Binding Protein 3/metabolism ; Tissue Inhibitor of Metalloproteinase-1/genetics ; Tissue Inhibitor of Metalloproteinase-1/metabolism ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/metabolism ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor Receptor-2/genetics ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Tandem Mass Spectrometry ; Chromatography, Liquid ; Angiogenesis Inhibitors/therapeutic use

Repurposing schirmer strips for tear biomarker profiling using infrared spectroscopy.

Autoren: Yu H Wu W Cui J et al.

Quelle: The ocular surface [Ocul Surf] 2025 Oct; Vol. 38, pp. 330-336. Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101156063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-5913 (Electronic) Linking ISSN: 15420124 NLM ISO Abbreviation: Ocul Surf Subsets: MEDLINE

MeSH-Schlagworte: Tears*/chemistry , Tears*/metabolism , Biomarkers*/metabolism , Biomarkers*/analysis , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/metabolism , Eye Proteins*/metabolism , Reagent Strips*, Humans ; Spectroscopy, Fourier Transform Infrared/methods ; Female ; Male ; Middle Aged ; Adult ; Aged