Search Results - "Tandem Mass Spectrometry"

Development, validation and clinical implementation of a HPLC-MS/MS method for the simultaneous quantification of bictegravir, emtricitabine, doravirine, cabotegravir, lenacapavir, fostemsavir, tenofovir alafenamide and the corresponding metabolites temsavir and tenofovir, in human plasma.

Authors: Mattino A Ferrari D Nozza S et al.

Source: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2025 Dec 15; Vol. 1267, pp. 124803. Date of Electronic Publication: 2025 Oct 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods, Humans ; Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Limit of Detection ; Linear Models ; Tenofovir/blood ; Tenofovir/analogs & derivatives ; Pyridones/blood ; Emtricitabine/blood ; Heterocyclic Compounds, 4 or More Rings/blood ; Male ; Adenine/blood ; Adenine/analogs & derivatives ; Alanine ; Drug Monitoring ; Liquid Chromatography-Mass Spectrometry ; Heterocyclic Compounds, 3-Ring ; Piperazines ; Indazoles ; Acetamides ; Amides

Targeted Metabolomic Methods for ¹³ C Stable Isotope Labeling with Uniformly Labeled Glucose and Glutamine Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

Authors: Jennings EQ Rathmell WK Rathmell JC

Source: Journal of proteome research [J Proteome Res] 2025 Dec 05; Vol. 24 (12), pp. 6328-6337. Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

MeSH Terms: Glutamine*/metabolism , Glutamine*/chemistry , Isotope Labeling*/methods , Tandem Mass Spectrometry*/methods , Glucose*/metabolism , Glucose*/chemistry , Metabolomics*/methods, Carbon Isotopes/chemistry ; Chromatography, Liquid/methods ; Citric Acid Cycle ; Glycolysis ; Humans ; Liquid Chromatography-Mass Spectrometry

Medium-chain Acyl-CoA Dehydrogenase Deficiency Identified by MS/MS Newborn Screening Challenges.

Authors: Głąb-Jabłońska E Taybert J Wiśniewska A et al.

Source: Journal of mother and child [J Mother Child] 2025 Dec 04; Vol. 29 (1), pp. 227-233. Date of Electronic Publication: 2025 Dec 04 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Sciendo Country of Publication: Poland NLM ID: 101771247 Publication Model: eCollection Cited Medium: Internet ISSN: 2719-535X (Electronic) Linking ISSN: 1428345X NLM ISO Abbreviation: J Mother Child Subsets: MEDLINE

MeSH Terms: Neonatal Screening*/methods , Lipid Metabolism, Inborn Errors*/diagnosis , Lipid Metabolism, Inborn Errors*/blood , Tandem Mass Spectrometry*/methods , Acyl-CoA Dehydrogenase*/deficiency , Acyl-CoA Dehydrogenase*/blood, Humans ; Infant, Newborn ; Female ; Male ; Carnitine/analogs & derivatives ; Carnitine/blood ; Dried Blood Spot Testing

SCR Disease Name: Medium chain acyl CoA dehydrogenase deficiency

Sensitive and Selective Quantification of Acrylamide in French Fries and Canola Oil by Fluorous Derivatization with Liquid Chromatography-Tandem Mass Spectrometry.

Authors: Kawasue S Shigematsu T Sonogi K et al.

Source: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2025 Dec 03; Vol. 36 (12), pp. 2660-2665. Date of Electronic Publication: 2025 Nov 14.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 9010412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1123 (Electronic) Linking ISSN: 10440305 NLM ISO Abbreviation: J Am Soc Mass Spectrom Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Acrylamide*/analysis , Acrylamide*/chemistry , Rapeseed Oil*/chemistry , Solanum tuberosum*/chemistry , Food Analysis*/methods, Chromatography, Liquid/methods ; Limit of Detection ; Food Contamination/analysis ; Reproducibility of Results

Forensic detection and quantification of methomyl in animal stomach contents using liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS) and liquid Chromatography tandem mass spectrometry (LC-MS/MS) in Japan.

Authors: Yohannes YB Tanaka A Kihara Y et al.

Source: The Journal of veterinary medical science [J Vet Med Sci] 2025 Dec 03; Vol. 87 (12), pp. 1494-1498. Date of Electronic Publication: 2025 Oct 29.

Publication Type: Journal Article

Journal Info: Publisher: Japanese Society Of Veterinary Science Country of Publication: Japan NLM ID: 9105360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-7439 (Electronic) Linking ISSN: 09167250 NLM ISO Abbreviation: J Vet Med Sci Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/veterinary , Tandem Mass Spectrometry*/methods , Gastrointestinal Contents*/chemistry , Methomyl*/analysis , Methomyl*/poisoning, Animals ; Japan ; Dogs ; Chromatography, Liquid/veterinary ; Chromatography, Liquid/methods ; Cats ; Male ; Female ; Liquid Chromatography-Mass Spectrometry

Top-Down Mass Spectrometry of a Clinical Antibody Light Chain Using the Omnitrap-Orbitrap-Booster Platform.

Authors: Garcia C Khristenko NA Fu T et al.

Source: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2025 Dec 03; Vol. 36 (12), pp. 2647-2659. Date of Electronic Publication: 2025 Nov 06.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 9010412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1123 (Electronic) Linking ISSN: 10440305 NLM ISO Abbreviation: J Am Soc Mass Spectrom Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Tandem Mass Spectrometry*/instrumentation , Immunoglobulin Light Chains*/chemistry , Immunoglobulin Light Chains*/analysis, Humans ; Multiple Myeloma ; Fourier Analysis

Quantitation of Plasma Bedaquiline Concentrations in Indian MDR-TB Patients Using Liquid Chromatography-Tandem Mass Spectrometry.

Authors: Lokhande RV Arora PR Joubert A et al.

Corporate Authors: Lokhande RV Arora PR Joubert A et al.

Source: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Dec; Vol. 39 (12), pp. e70243.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Diarylquinolines*/blood , Diarylquinolines*/pharmacokinetics , Diarylquinolines*/therapeutic use , Diarylquinolines*/chemistry , Tuberculosis, Multidrug-Resistant*/drug therapy , Tuberculosis, Multidrug-Resistant*/blood , Antitubercular Agents*/blood , Antitubercular Agents*/pharmacokinetics , Antitubercular Agents*/therapeutic use, Humans ; India ; Reproducibility of Results ; Male ; Linear Models ; Chromatography, Liquid/methods ; Adult ; Female ; Limit of Detection ; Middle Aged ; Sensitivity and Specificity

Aptamer-functionalized magnetic covalent organic frameworks for rapid extraction and LC-MS/MS quantification of gentamicin in milk.

Authors: Liu H Cao H Xiang Y et al.

Source: Food chemistry [Food Chem] 2025 Nov 30; Vol. 493 (Pt 3), pp. 145889. Date of Electronic Publication: 2025 Aug 10.

Publication Type: Journal Article; Evaluation Study

Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH Terms: Milk*/chemistry , Tandem Mass Spectrometry*/methods , Solid Phase Extraction*/methods , Solid Phase Extraction*/instrumentation , Gentamicins*/isolation & purification , Gentamicins*/chemistry , Gentamicins*/analysis , Anti-Bacterial Agents*/isolation & purification , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/analysis , Metal-Organic Frameworks*/chemistry , Aptamers, Nucleotide*/chemistry , Drug Residues*/isolation & purification , Drug Residues*/chemistry, Animals ; Food Contamination/analysis ; Cattle ; Adsorption ; Chromatography, Liquid/methods ; Limit of Detection ; Chromatography, High Pressure Liquid/methods ; Liquid Chromatography-Mass Spectrometry

[Determination of glyphosate and glufosinate in plasma samples by solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry].

Authors: Pan SD Qiu QL Wang L

Source: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases [Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi] 2025 Nov 20; Vol. 43 (11), pp. 865-868.

Publication Type: English Abstract; Journal Article

Journal Info: Publisher: Tianjin shi lao dong wei sheng yan jiu suo ; Tianjin shi lao dong wei sheng huan jing yi xue hui Country of Publication: China NLM ID: 8410840 Publication Model: Print Cited Medium: Print ISSN: 1001-9391 (Print) Linking ISSN: 10019391 NLM ISO Abbreviation: Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Glycine*/analogs & derivatives , Glycine*/blood , Solid Phase Extraction*/methods , Aminobutyrates*/blood, Glyphosate ; Humans ; Chromatography, Liquid/methods

QuantyFey: An open-source tool for targeted LC-MS quantification with integrated drift correction.

Authors: Aigensberger M Bueschl C Metzler-Zebeli BU et al.

Source: Analytica chimica acta [Anal Chim Acta] 2025 Nov 15; Vol. 1375, pp. 344571. Date of Electronic Publication: 2025 Aug 26.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4324 (Electronic) Linking ISSN: 00032670 NLM ISO Abbreviation: Anal Chim Acta Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Amino Acids*/blood , Amino Acids*/metabolism , Software*, Animals ; Chromatography, Liquid ; Swine ; Quality Control ; Calibration ; Liquid Chromatography-Mass Spectrometry

Development and validation of an ion pairing LC-Q-Orbitrap method with diverter valve for the quantitative analysis of aminoglycosides in animal-derived matrices and honey for routine applications.

Authors: Khaled O Ryad L Medhat M et al.

Source: Food chemistry [Food Chem] 2025 Nov 15; Vol. 492 (Pt 1), pp. 145336. Date of Electronic Publication: 2025 Jun 26.

Publication Type: Journal Article; Validation Study; Evaluation Study

Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH Terms: Honey*/analysis , Milk*/chemistry , Food Contamination*/analysis , Aminoglycosides*/analysis , Aminoglycosides*/isolation & purification , Anti-Bacterial Agents*/analysis , Anti-Bacterial Agents*/isolation & purification , Meat*/analysis , Drug Residues*/isolation & purification , Drug Residues*/analysis , Tandem Mass Spectrometry*/methods , Tandem Mass Spectrometry*/instrumentation, Animals ; Chromatography, High Pressure Liquid/methods ; Chromatography, High Pressure Liquid/instrumentation ; Liver/chemistry ; Limit of Detection ; Cattle

Residue depletion study and withdrawal period in milk for intramuscular gentamicin in dairy cows using LC-MS/MS.

Authors: Kim D Nam SM Moon H et al.

Source: Journal of veterinary science [J Vet Sci] 2025 Nov; Vol. 26 (6), pp. e89.

Publication Type: Journal Article

Journal Info: Publisher: Korean Society of Veterinary Science Country of Publication: Korea (South) NLM ID: 100964185 Publication Model: Print Cited Medium: Internet ISSN: 1976-555X (Electronic) Linking ISSN: 1229845X NLM ISO Abbreviation: J Vet Sci Subsets: MEDLINE

MeSH Terms: Milk*/chemistry , Tandem Mass Spectrometry*/veterinary , Tandem Mass Spectrometry*/methods , Gentamicins*/administration & dosage , Gentamicins*/analysis , Gentamicins*/chemistry , Drug Residues*/analysis , Anti-Bacterial Agents*/analysis , Anti-Bacterial Agents*/administration & dosage , Anti-Bacterial Agents*/chemistry, Animals ; Cattle ; Female ; Chromatography, Liquid/veterinary ; Chromatography, Liquid/methods ; Injections, Intramuscular/veterinary ; Liquid Chromatography-Mass Spectrometry

LC-MS/MS-Based Serum Lipidomic Profile to Reveal Cancer-Specific Biomarkers for Renal Cell Carcinoma.

Authors: Lin L Zheng J Hu S

Source: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Nov; Vol. 39 (11), pp. e70230.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

MeSH Terms: Carcinoma, Renal Cell*/blood , Tandem Mass Spectrometry*/methods , Kidney Neoplasms*/blood , Biomarkers, Tumor*/blood , Lipidomics*/methods , Lipids*/blood, Humans ; Male ; Female ; Middle Aged ; Chromatography, Liquid/methods ; Adult ; Aged ; ROC Curve ; Reproducibility of Results ; Case-Control Studies ; Liquid Chromatography-Mass Spectrometry

Quantitative LC-MS/MS profiling of N-Acetylcysteine in chicken plasma: Method validation and pharmacokinetic characterization.

Authors: Zhang Y Chen J Lin W et al.

Source: Poultry science [Poult Sci] 2025 Nov; Vol. 104 (11), pp. 105777. Date of Electronic Publication: 2025 Sep 03.

Publication Type: Journal Article; Validation Study

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0401150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-3171 (Electronic) Linking ISSN: 00325791 NLM ISO Abbreviation: Poult Sci Subsets: MEDLINE

MeSH Terms: Chickens*/blood , Chickens*/metabolism , Acetylcysteine*/pharmacokinetics , Acetylcysteine*/blood , Acetylcysteine*/administration & dosage , Tandem Mass Spectrometry*/veterinary , Tandem Mass Spectrometry*/methods, Animals ; Chromatography, Liquid/veterinary ; Chromatography, Liquid/methods ; Administration, Oral ; Male ; Dose-Response Relationship, Drug ; Reproducibility of Results ; Liquid Chromatography-Mass Spectrometry

[Determination of genotoxic impurity in the bulk drug of crizotinib by high performance liquid chromatography-electrospray ionization tandem mass spectrometry].

Authors: Zhan XB Qin Y Yan Y et al.

Source: Se pu = Chinese journal of chromatography [Se Pu] 2025 Nov; Vol. 43 (11), pp. 1262-1267.

Publication Type: English Abstract; Journal Article

Journal Info: Publisher: Hua xue za zhi she Country of Publication: China NLM ID: 9424804 Publication Model: Print Cited Medium: Internet ISSN: 1872-2059 (Electronic) Linking ISSN: 10008713 NLM ISO Abbreviation: Se Pu Subsets: MEDLINE

MeSH Terms: Spectrometry, Mass, Electrospray Ionization*/methods , Drug Contamination* , Tandem Mass Spectrometry*/methods , Pyridines*/analysis , Pyrazoles*/analysis , Mutagens*/analysis, Crizotinib ; Chromatography, High Pressure Liquid/methods

[Quantitation of cow's milk allergen in hypoallergenic infant formulas using ultra-high performance liquid chromatography- tandem mass spectrometry].

Authors: Xu DK Yang Y Huang HL et al.

Source: Se pu = Chinese journal of chromatography [Se Pu] 2025 Nov; Vol. 43 (11), pp. 1244-1251.

Publication Type: English Abstract; Journal Article

Journal Info: Publisher: Hua xue za zhi she Country of Publication: China NLM ID: 9424804 Publication Model: Print Cited Medium: Internet ISSN: 1872-2059 (Electronic) Linking ISSN: 10008713 NLM ISO Abbreviation: Se Pu Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Allergens*/analysis , Infant Formula*/chemistry , Milk Proteins*/analysis, Chromatography, High Pressure Liquid/methods ; Milk Hypersensitivity/prevention & control ; Animals ; Cattle ; Humans ; Infant

[Determination of 51 per- and polyfluoroalkyl substances in raw water and drinking water by online solid-phase extraction coupled with ultra performance liquid chromatography- tandem mass spectrometry].

Authors: Chen YY Lyu J Ye BX et al.

Source: Se pu = Chinese journal of chromatography [Se Pu] 2025 Nov; Vol. 43 (11), pp. 1222-1234.

Publication Type: English Abstract; Journal Article

Journal Info: Publisher: Hua xue za zhi she Country of Publication: China NLM ID: 9424804 Publication Model: Print Cited Medium: Internet ISSN: 1872-2059 (Electronic) Linking ISSN: 10008713 NLM ISO Abbreviation: Se Pu Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Solid Phase Extraction*/methods , Drinking Water*/analysis , Drinking Water*/chemistry , Water Pollutants, Chemical*/analysis , Fluorocarbons*/analysis, Chromatography, High Pressure Liquid/methods

Development and Validation of a Rapid and Simple UHPLC-MS/MS Method for the Determination of Colchicine in Human Plasma.

Authors: Žideková N Pršo K Pršo M et al.

Source: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Nov; Vol. 39 (11), pp. e70222.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

MeSH Terms: Colchicine*/blood , Colchicine*/chemistry , Tandem Mass Spectrometry*/methods, Humans ; Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Linear Models ; Limit of Detection ; Familial Mediterranean Fever/drug therapy ; Familial Mediterranean Fever/blood ; Sensitivity and Specificity

Liquid Chromatography-Mass Spectrometry Method for the Estimation of Tacrolimus From Whole Blood Using Novel Time Programming Coupled With Diverter Valve Plumbing to Overcome the Matrix Effect.

Authors: Dar SK Khuroo AH Akhtar M et al.

Source: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Nov; Vol. 39 (11), pp. e70227.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

MeSH Terms: Tacrolimus*/blood , Tacrolimus*/pharmacokinetics , Tacrolimus*/chemistry , Tandem Mass Spectrometry*/methods , Tandem Mass Spectrometry*/instrumentation , Immunosuppressive Agents*/blood, Humans ; Reproducibility of Results ; Chromatography, Liquid/methods ; Linear Models ; Limit of Detection ; Therapeutic Equivalency ; Sensitivity and Specificity ; Liquid Chromatography-Mass Spectrometry

[Determination of eight per- and polyfluoroalkyl substances in seawater using dispersive membrane extraction-ultra-high performance liquid chromatography-tandem mass spectrometry].

Authors: Ren Z Ma JP Liu YJ et al.

Source: Se pu = Chinese journal of chromatography [Se Pu] 2025 Nov; Vol. 43 (11), pp. 1235-1243.

Publication Type: English Abstract; Journal Article

Journal Info: Publisher: Hua xue za zhi she Country of Publication: China NLM ID: 9424804 Publication Model: Print Cited Medium: Internet ISSN: 1872-2059 (Electronic) Linking ISSN: 10008713 NLM ISO Abbreviation: Se Pu Subsets: MEDLINE

MeSH Terms: Tandem Mass Spectrometry*/methods , Fluorocarbons*/analysis , Fluorocarbons*/isolation & purification , Seawater*/chemistry , Seawater*/analysis , Water Pollutants, Chemical*/analysis , Water Pollutants, Chemical*/isolation & purification, Chromatography, High Pressure Liquid/methods ; Alkanesulfonic Acids/analysis