Search Results - "TUMOR necrosis factors"

Increased expression of membrane-bound TGF-β1, GITR, and GITR ligand in patients with autoimmune thyroid disease.

Authors: Hayashi F Inoue N Iwatani Y et al.

Source: Immunology letters [Immunol Lett] 2025 Dec; Vol. 276, pp. 107036. Date of Electronic Publication: 2025 May 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7910006 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0542 (Electronic) Linking ISSN: 01652478 NLM ISO Abbreviation: Immunol Lett Subsets: MEDLINE

MeSH Terms: Transforming Growth Factor beta1*/metabolism , Transforming Growth Factor beta1*/genetics , Glucocorticoid-Induced TNFR-Related Protein*/metabolism , Glucocorticoid-Induced TNFR-Related Protein*/genetics , T-Lymphocytes, Regulatory*/immunology , T-Lymphocytes, Regulatory*/metabolism , Tumor Necrosis Factors*/metabolism , Tumor Necrosis Factors*/genetics , Thyroiditis, Autoimmune*/immunology , Thyroiditis, Autoimmune*/metabolism, Humans ; Female ; Male ; Adult ; Middle Aged

TNF superfamily molecules in atherosclerosis: mechanistic insights and therapeutic translation.

Authors: Luo J Zhang J Xie Y et al.

Source: Frontiers in immunology [Front Immunol] 2025 Nov 05; Vol. 16, pp. 1629577. Date of Electronic Publication: 2025 Nov 05 (Print Publication: 2025).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: Atherosclerosis*/metabolism , Atherosclerosis*/immunology , Atherosclerosis*/drug therapy , Atherosclerosis*/etiology , Atherosclerosis*/therapy , Tumor Necrosis Factors*/metabolism , Tumor Necrosis Factors*/immunology, Humans ; Animals ; Signal Transduction ; Biomarkers ; Immunotherapy/methods

Overexpression of GitrL in Recombinant Rabies Virus rLBNSE-GitrL Enhances Innate Immunity by Activating Dendritic Cells and Innate Immune-Related Pathways and Genes.

Authors: Wang Y Xing X Xiong Z et al.

Source: Viruses [Viruses] 2025 Oct 09; Vol. 17 (10). Date of Electronic Publication: 2025 Oct 09.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

MeSH Terms: Rabies virus*/genetics , Rabies virus*/immunology , Dendritic Cells*/immunology , Immunity, Innate* , Tumor Necrosis Factors*/genetics , Tumor Necrosis Factors*/immunology, Animals ; Mice ; Rabies/immunology ; Rabies/prevention & control ; Antibodies, Viral/blood ; Antibodies, Viral/immunology ; Rabies Vaccines/immunology ; Rabies Vaccines/genetics ; Rabies Vaccines/administration & dosage ; Female ; Signal Transduction ; Humans

Multifunctional Roles and Therapeutic Prospects of C1q/TNF-Related Protein 3 (CTRP3) in Human Diseases.

Authors: Wang QP Wang C Yuan YH et al.

Source: Current medical science [Curr Med Sci] 2025 Oct; Vol. 45 (5), pp. 1023-1033. Date of Electronic Publication: 2025 Sep 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: Huazhong University of Science and Technology Country of Publication: China NLM ID: 101729993 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2523-899X (Electronic) Linking ISSN: 2523899X NLM ISO Abbreviation: Curr Med Sci Subsets: MEDLINE

MeSH Terms: Tumor Necrosis Factors*/metabolism , Tumor Necrosis Factors*/genetics, Humans ; Adipose Tissue/metabolism ; Adipokines/metabolism ; Adipokines/genetics ; Animals

Exercise intensity affects circulating C1q/TNF-related proteins and follistatin-like 1 concentrations.

Authors: Kon M Watanabe K

Source: Clinical physiology and functional imaging [Clin Physiol Funct Imaging] 2025 Nov; Vol. 45 (6), pp. e70036.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Country of Publication: England NLM ID: 101137604 Publication Model: Print Cited Medium: Internet ISSN: 1475-097X (Electronic) Linking ISSN: 14750961 NLM ISO Abbreviation: Clin Physiol Funct Imaging Subsets: MEDLINE

MeSH Terms: Follistatin-Related Proteins*/blood , Adiponectin*/blood , Tumor Necrosis Factors*/blood , Glycoproteins*/blood , Complement C1q*/metabolism , Exercise*, Humans ; Male ; Adult ; Young Adult ; Cross-Over Studies ; Time Factors ; Biomarkers/blood ; Energy Metabolism

The mechanism of C1q/TNF-related proteins (CTRPs) in atherosclerosis associated with type 2 diabetes mellitus.

Authors: Song R Cheng R Zhang G et al.

Source: European journal of medical research [Eur J Med Res] 2025 Oct 24; Vol. 30 (1), pp. 1015. Date of Electronic Publication: 2025 Oct 24.

Publication Type: Journal Article; Review

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9517857 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-783X (Electronic) Linking ISSN: 09492321 NLM ISO Abbreviation: Eur J Med Res Subsets: MEDLINE

MeSH Terms: Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/metabolism , Atherosclerosis*/metabolism , Atherosclerosis*/etiology , Atherosclerosis*/blood , Atherosclerosis*/complications , Complement C1q*/metabolism , Tumor Necrosis Factors*/metabolism, Humans

The gene characteristics and adaptive evolution of the tumor necrosis factor superfamily (TNFSF) in miiuy croaker, Miichthysmiiuy.

Authors: Su X Cui Y Gong H et al.

Source: Fish & shellfish immunology [Fish Shellfish Immunol] 2025 Aug; Vol. 163, pp. 110369. Date of Electronic Publication: 2025 Apr 25.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE

MeSH Terms: Fish Proteins*/genetics , Fish Proteins*/chemistry , Fish Proteins*/immunology , Evolution, Molecular* , Tumor Necrosis Factors*/genetics , Tumor Necrosis Factors*/chemistry , Tumor Necrosis Factors*/immunology , Perciformes*/genetics , Perciformes*/immunology , Immunity, Innate*/genetics, Animals ; Phylogeny ; Sequence Alignment/veterinary ; Amino Acid Sequence

Research advances in structure and functions of complement C1q/tumor necrosis factor-related protein 4: A review.

Authors: Liang C Shen L Zhao H et al.

Source: International journal of biological macromolecules [Int J Biol Macromol] 2025 Aug; Vol. 320 (Pt 1), pp. 145852. Date of Electronic Publication: 2025 Jul 08.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH Terms: Adipokines*/metabolism , Adipokines*/chemistry , Adipokines*/genetics , Tumor Necrosis Factors*/metabolism , Tumor Necrosis Factors*/chemistry , Tumor Necrosis Factors*/genetics, Humans ; Animals ; Signal Transduction

Identification and Validation of a Prognostic Model Based on Tumour Necrosis Factor-Related mRNAs for Kidney Renal Clear Cell Carcinoma.

Authors: Hu Z Zhou Y Xie L et al.

Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2025 Jul; Vol. 29 (14), pp. e70657.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

MeSH Terms: Carcinoma, Renal Cell*/genetics , Carcinoma, Renal Cell*/pathology , Carcinoma, Renal Cell*/mortality , Kidney Neoplasms*/genetics , Kidney Neoplasms*/pathology , Kidney Neoplasms*/mortality , RNA, Messenger*/genetics , RNA, Messenger*/metabolism , Tumor Necrosis Factors*/genetics , Tumor Necrosis Factors*/metabolism, Humans ; Prognosis ; Nomograms ; Gene Expression Regulation, Neoplastic ; Female ; Male ; Biomarkers, Tumor/genetics ; Kaplan-Meier Estimate ; Middle Aged ; Gene Expression Profiling

GITRL enhances cytotoxicity and persistence of CAR-T cells in cancer therapy.

Authors: Tan B Tu C Xiong H et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2025 Jun 04; Vol. 33 (6), pp. 2789-2800. Date of Electronic Publication: 2025 Jan 25.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

MeSH Terms: Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/metabolism , Immunotherapy, Adoptive*/methods , Tumor Necrosis Factors*/genetics , Tumor Necrosis Factors*/metabolism , Glucocorticoid-Induced TNFR-Related Protein*/genetics , Glucocorticoid-Induced TNFR-Related Protein*/metabolism , Neoplasms*/therapy , Neoplasms*/immunology , Cytotoxicity, Immunologic* , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism, Animals ; Humans ; Mice ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Male ; Disease Models, Animal

TNF/TNFR Superfamily Members in Costimulation of T Cell Responses-Revisited.

Authors: Watts TH Yeung KKM Yu T et al.

Source: Annual review of immunology [Annu Rev Immunol] 2025 Apr; Vol. 43 (1), pp. 113-142. Date of Electronic Publication: 2025 Jan 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: Annual Reviews Inc Country of Publication: United States NLM ID: 8309206 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-3278 (Electronic) Linking ISSN: 07320582 NLM ISO Abbreviation: Annu Rev Immunol Subsets: MEDLINE

MeSH Terms: Receptors, Tumor Necrosis Factor*/metabolism , Receptors, Tumor Necrosis Factor*/immunology , Receptors, Tumor Necrosis Factor*/genetics , Tumor Necrosis Factors*/metabolism , Tumor Necrosis Factors*/immunology , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism, Humans ; Animals ; Signal Transduction ; Lymphocyte Activation/immunology ; Antigen-Presenting Cells/immunology

Comprehensive characterization of pathogenic missense CTRP6 variants and their association with cancer.

Authors: Mehboob MZ Hamid A Senthil Kumar J et al.

Source: BMC cancer [BMC Cancer] 2025 Feb 20; Vol. 25 (1), pp. 304. Date of Electronic Publication: 2025 Feb 20.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

MeSH Terms: Mutation, Missense* , Neoplasms*/genetics , Tumor Necrosis Factors*/genetics , Tumor Necrosis Factors*/chemistry, Humans ; Polymorphism, Single Nucleotide ; Genetic Predisposition to Disease ; Molecular Dynamics Simulation ; Computational Biology/methods ; Protein Conformation ; Genome-Wide Association Study ; Collagen

In situ blockade of TNF-TNFR2 axis via oncolytic adenovirus improves antitumor efficacy in solid tumors.

Authors: Kang X Han Y Wu M et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2025 Feb 05; Vol. 33 (2), pp. 670-687. Date of Electronic Publication: 2024 Dec 16.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

MeSH Terms: Adenoviridae*/genetics , Tumor Necrosis Factors*/chemistry , Tumor Necrosis Factors*/genetics , Tumor Necrosis Factors*/metabolism , Receptors, Tumor Necrosis Factor, Type II*/chemistry , Receptors, Tumor Necrosis Factor, Type II*/genetics , Receptors, Tumor Necrosis Factor, Type II*/metabolism , Neoplasms*/genetics , Neoplasms*/metabolism , Neoplasms*/pathology, Humans ; Animals ; Cricetinae ; Cell Line ; Male ; Mice ; Mice, Inbred C57BL ; Disease Progression ; Mice, Inbred BALB C ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Lymphocytes, Tumor-Infiltrating/immunology ; CD8-Positive T-Lymphocytes/immunology ; Protein Binding ; Models, Molecular ; Protein Structure, Tertiary ; Protein Structure, Quaternary ; Immune Checkpoint Inhibitors/pharmacology ; Tyrosine Kinase Inhibitors/pharmacology

Soluble B7 and TNF family in colorectal cancer: Serum level, prognostic and treatment value.

Authors: Sharafi Monfared M Nazmi S Parhizkar F et al.

Source: Human immunology [Hum Immunol] 2025 Mar; Vol. 86 (2), pp. 111232. Date of Electronic Publication: 2025 Jan 09.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier/North-Holland Country of Publication: United States NLM ID: 8010936 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1166 (Electronic) Linking ISSN: 01988859 NLM ISO Abbreviation: Hum Immunol Subsets: MEDLINE

MeSH Terms: Colorectal Neoplasms*/diagnosis , Colorectal Neoplasms*/blood , Colorectal Neoplasms*/therapy , Colorectal Neoplasms*/immunology , Biomarkers, Tumor*/blood , B7 Antigens*/blood , Tumor Necrosis Factors*/blood, Humans ; Prognosis ; Tumor Microenvironment/immunology

Low serum CTRP3 is related to more severe distal symmetric polyneuropathy in type 2 diabetes patients.

Authors: Han P Hu F Guo J et al.

Source: Hormones (Athens, Greece) [Hormones (Athens)] 2025 Mar; Vol. 24 (1), pp. 99-107. Date of Electronic Publication: 2024 Aug 19.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101142469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2520-8721 (Electronic) Linking ISSN: 11093099 NLM ISO Abbreviation: Hormones (Athens) Subsets: MEDLINE

MeSH Terms: Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/complications , Tumor Necrosis Factors*/blood , Diabetic Neuropathies*/blood , Diabetic Neuropathies*/diagnosis , Diabetic Neuropathies*/etiology , Diabetic Neuropathies*/epidemiology , Adipokines*/blood , Polyneuropathies*/blood, Humans ; Male ; Female ; Middle Aged ; Aged ; Biomarkers/blood ; Severity of Illness Index

Evaluation of the serum level of CTRP-3 and CTRP-6 in patients with Hashimoto's disease and correlation with thyroid hormones and lipid profile.

Authors: Al-Abboody RS Heydari N Saravani M et al.

Source: Journal of basic and clinical physiology and pharmacology [J Basic Clin Physiol Pharmacol] 2025 Jan 21; Vol. 36 (1), pp. 61-67. Date of Electronic Publication: 2025 Jan 21 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Walter de Gruyter Country of Publication: Germany NLM ID: 9101750 Publication Model: eCollection Cited Medium: Internet ISSN: 2191-0286 (Electronic) Linking ISSN: 07926855 NLM ISO Abbreviation: J Basic Clin Physiol Pharmacol Subsets: MEDLINE

MeSH Terms: Hashimoto Disease*/blood , Thyroid Hormones*/blood , Lipids*/blood , Adipokines*/blood , Tumor Necrosis Factors*/blood, Humans ; Female ; Male ; Adult ; Middle Aged ; Case-Control Studies ; Thyrotropin/blood ; Collagen

Tumour necrosis factor-like weak inducer of apoptosis participates in the development of cutaneous fibrosis in an experimental systemic sclerosis model.

Authors: Lu M Wang X Kang S et al.

Source: Clinical and experimental rheumatology [Clin Exp Rheumatol] 2025 Jan; Vol. 43 (1), pp. 14-20. Date of Electronic Publication: 2024 Dec 23.

Publication Type: Journal Article

Journal Info: Publisher: Clinical And Experimental Rheumatology S.A.S Country of Publication: Italy NLM ID: 8308521 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0392-856X (Print) Linking ISSN: 0392856X NLM ISO Abbreviation: Clin Exp Rheumatol Subsets: MEDLINE

MeSH Terms: Scleroderma, Systemic*/metabolism , Scleroderma, Systemic*/pathology , Scleroderma, Systemic*/chemically induced , Skin*/pathology , Skin*/metabolism , Skin*/drug effects , Tumor Necrosis Factors*/metabolism, Animals ; TWEAK Receptor/metabolism ; Cytokine TWEAK/metabolism ; Disease Models, Animal ; Fibrosis ; Humans ; Signal Transduction ; Bleomycin ; Female ; Mice ; Male ; Mice, Inbred C57BL ; Middle Aged

Tumor necrosis factor superfamily signaling: life and death in cancer.

Authors: Ababneh O Nishizaki D Kato S et al.

Source: Cancer metastasis reviews [Cancer Metastasis Rev] 2024 Dec; Vol. 43 (4), pp. 1137-1163. Date of Electronic Publication: 2024 Oct 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8605731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7233 (Electronic) Linking ISSN: 01677659 NLM ISO Abbreviation: Cancer Metastasis Rev Subsets: MEDLINE

MeSH Terms: Neoplasms*/metabolism , Neoplasms*/pathology , Neoplasms*/drug therapy , Signal Transduction* , Tumor Necrosis Factors*/metabolism, Humans ; Animals ; Receptors, Tumor Necrosis Factor/metabolism

Investigation of the Effects of Chrysin Against Amoxycillin-Clavulanic Acid-Induced Kidney Injury in Rats.

Alternate Title: Sıçanlarda Amoksisilin/Klavulanik Asit ile Oluşturulan Böbrek Hasarına Karşı Krisin'in Etkilerinin Araştırılması.

Authors: AYGÖRMEZ, Serpil DALKILINÇ, Elif AKARAS, Nurhan et al.

Source: Van Veterinary Journal. Jul2025, Vol. 36 Issue 2, p139-145. 7p.

Subjects: NF-kappa B, Tumor necrosis factors, Glutathione peroxidase, Superoxide dismutase, Kidney physiology

Tuberculosis in otherwise healthy adults with inherited TNF deficiency.

Authors: Arias AA Neehus AL Ogishi M et al.

Source: Nature [Nature] 2024 Sep; Vol. 633 (8029), pp. 417-425. Date of Electronic Publication: 2024 Aug 28.

Publication Type: Journal Article; Case Reports

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

MeSH Terms: Macrophages*/cytology , Macrophages*/drug effects , Macrophages*/immunology , Macrophages*/metabolism , Macrophages*/pathology , Tuberculosis, Pulmonary*/immunology , Tuberculosis, Pulmonary*/microbiology , Tuberculosis, Pulmonary*/genetics , Tumor Necrosis Factors*/deficiency , Tumor Necrosis Factors*/genetics, Adult ; Female ; Humans ; Male ; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism ; Homozygote ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/immunology ; Induced Pluripotent Stem Cells/cytology ; Inflammation/immunology ; Interferon-gamma/immunology ; Loss of Function Mutation ; Lung/cytology ; Lung/drug effects ; Macrophages, Alveolar/cytology ; Macrophages, Alveolar/drug effects ; Macrophages, Alveolar/immunology ; Macrophages, Alveolar/microbiology ; Macrophages, Alveolar/pathology ; Mycobacterium tuberculosis/immunology ; Phenotype ; Reactive Oxygen Species/metabolism ; Receptors, Tumor Necrosis Factor, Type I/deficiency ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Respiratory Burst ; Tumor Necrosis Factor Inhibitors/pharmacology ; Adolescent ; Young Adult