Výsledky vyhľadávania - "TRANSITION"

PM 2.5 Induce Endothelial-Mesenchymal Transition and Cardiac Fibrosis via the NCOA4-Mediated Ferritinophagy.

Autori: Sun Q Wang M Liu L a ďalší

Zdroj: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Dec; Vol. 12 (45), pp. e07536. Date of Electronic Publication: 2025 Sep 15.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Particulate Matter*/adverse effects , Particulate Matter*/toxicity , Nuclear Receptor Coactivators*/metabolism , Nuclear Receptor Coactivators*/genetics , Ferritins*/metabolism , Myocardium*/pathology , Myocardium*/metabolism , Epithelial-Mesenchymal Transition*/drug effects, Fibrosis/metabolism ; Animals ; Mice ; Humans ; Mice, Inbred C57BL ; Endothelial Cells/metabolism ; Endothelial Cells/drug effects ; Male ; Endothelial-Mesenchymal Transition

Heparanase and MMP-9 synergistically induce endothelial-mesenchymal transition in portal vein microvessels to promote hepatocellular carcinoma metastasis.

Autori: Pan M Chen P Peng J a ďalší

Zdroj: Pathology, research and practice [Pathol Res Pract] 2025 Nov; Vol. 275, pp. 156229. Date of Electronic Publication: 2025 Sep 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0631 (Electronic) Linking ISSN: 03440338 NLM ISO Abbreviation: Pathol Res Pract Subsets: MEDLINE

Výrazy zo slovníka MeSH: Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , Liver Neoplasms*/enzymology , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/enzymology , Matrix Metalloproteinase 9*/metabolism , Matrix Metalloproteinase 9*/genetics , Epithelial-Mesenchymal Transition*/physiology , Glucuronidase*/metabolism , Glucuronidase*/genetics , Portal Vein*/pathology , Portal Vein*/metabolism, Humans ; Animals ; Mice ; Human Umbilical Vein Endothelial Cells/pathology ; Microvessels/pathology ; Microvessels/metabolism ; Mice, Nude ; Male ; Coculture Techniques ; Neoplasm Metastasis ; Mice, Inbred BALB C ; Endothelial-Mesenchymal Transition

Endothelial adenosine receptor 2A loss alleviates diabetic vascular calcification by blocking CREB1-SNAI1-driven EndMT.

Autori: Zhou Y Zhao D Ma Q a ďalší

Zdroj: Pharmacological research [Pharmacol Res] 2025 Nov; Vol. 221, pp. 107981. Date of Electronic Publication: 2025 Oct 09.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Receptor, Adenosine A2A*/genetics , Receptor, Adenosine A2A*/metabolism , Vascular Calcification*/metabolism , Vascular Calcification*/pathology , Vascular Calcification*/etiology , Cyclic AMP Response Element-Binding Protein*/metabolism , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/complications , Diabetes Mellitus, Experimental*/pathology , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects , Endothelial Cells*/pathology , Snail Family Transcription Factors*/metabolism , Epithelial-Mesenchymal Transition* , Diabetic Angiopathies*/metabolism , Diabetic Angiopathies*/pathology , Diabetic Angiopathies*/genetics, Animals ; Humans ; Male ; Mice, Inbred C57BL ; Mice ; Cells, Cultured ; Osteogenesis/drug effects ; Mice, Knockout ; Endothelial-Mesenchymal Transition

Integrative transcriptomic analysis identifies shared EndMT-related gene signatures in endometriosis and recurrent miscarriage.

Autori: Liang Y Yu L Zhou Q a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Oct 21; Vol. 15 (1), pp. 36654. Date of Electronic Publication: 2025 Oct 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Endometriosis*/genetics , Endometriosis*/pathology , Abortion, Habitual*/genetics , Abortion, Habitual*/pathology , Gene Expression Profiling* , Transcriptome* , Epithelial-Mesenchymal Transition*/genetics, Humans ; Female ; Protein Interaction Maps/genetics ; Computational Biology/methods ; Gene Regulatory Networks ; Gene Ontology ; Pregnancy ; Endothelial-Mesenchymal Transition

Unveiling the secret of cellular metamorphosis: the crucial role of EndMT mechanisms in COVID-19-induced pulmonary fibrosis.

Autori: Zhang X Tong X Hou R a ďalší

Zdroj: Inflammopharmacology [Inflammopharmacology] 2025 Oct; Vol. 33 (10), pp. 6251-6260. Date of Electronic Publication: 2025 Sep 24.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9112626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-5608 (Electronic) Linking ISSN: 09254692 NLM ISO Abbreviation: Inflammopharmacology Subsets: MEDLINE

Výrazy zo slovníka MeSH: COVID-19*/complications , COVID-19*/pathology , Pulmonary Fibrosis*/virology , Pulmonary Fibrosis*/pathology , Pulmonary Fibrosis*/etiology , Pulmonary Fibrosis*/metabolism , Epithelial-Mesenchymal Transition*/physiology, Humans ; Animals ; Endothelial Cells/pathology ; Endothelial Cells/metabolism ; SARS-CoV-2 ; Endothelial-Mesenchymal Transition

ANGPTL4 Prevents Atherosclerosis by Preserving KLF2 to Suppress EndMT and Mitigates Endothelial Dysfunction.

Autori: Cho DI Ahn JH Kang BG a ďalší

Zdroj: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2025 Oct; Vol. 45 (10), pp. 1742-1761. Date of Electronic Publication: 2025 Aug 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Angiopoietin-Like Protein 4*/genetics , Angiopoietin-Like Protein 4*/metabolism , Angiopoietin-Like Protein 4*/blood , Kruppel-Like Transcription Factors*/metabolism , Kruppel-Like Transcription Factors*/genetics , Atherosclerosis*/prevention & control , Atherosclerosis*/metabolism , Atherosclerosis*/pathology , Atherosclerosis*/genetics , Atherosclerosis*/physiopathology , Epithelial-Mesenchymal Transition* , Endothelium, Vascular*/metabolism , Endothelium, Vascular*/physiopathology , Endothelium, Vascular*/pathology , Coronary Artery Disease*/prevention & control , Coronary Artery Disease*/metabolism , Coronary Artery Disease*/pathology , Coronary Artery Disease*/physiopathology , Coronary Artery Disease*/genetics, Humans ; Animals ; Mice, Knockout, ApoE ; Disease Models, Animal ; Plaque, Atherosclerotic ; Male ; Human Umbilical Vein Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells/pathology ; Signal Transduction ; Mice, Inbred C57BL ; Female ; Cells, Cultured ; Mice ; Smad2 Protein/metabolism ; Middle Aged ; Endothelial-Mesenchymal Transition

Fei Wei formula attenuates pulmonary fibrosis by inhibiting lactate-driven endothelial mesenchymal transition via its target of HSP90ab1.

Autori: Gu JM Wang SL Zhang SN a ďalší

Zdroj: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Nov 25; Vol. 148, pp. 157501. Date of Electronic Publication: 2025 Oct 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

Výrazy zo slovníka MeSH: HSP90 Heat-Shock Proteins*/metabolism , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/metabolism , Drugs, Chinese Herbal*/pharmacology , Epithelial-Mesenchymal Transition*/drug effects , Pulmonary Fibrosis*/drug therapy , Lactic Acid*/metabolism, Animals ; Humans ; Mice ; Bleomycin ; Male ; Mice, Inbred C57BL ; Endothelial Cells/drug effects ; Disease Models, Animal ; Female ; Endothelial-Mesenchymal Transition

Betulinic acid as a novel AT1R inhibitor: attenuation of liver fibrosis via modulation of endothelial-mesenchymal transition in chronic hepatic injury.

Autori: Zhu B Dai X Liu C a ďalší

Zdroj: Journal of translational medicine [J Transl Med] 2025 Nov 13; Vol. 23 (1), pp. 1282. Date of Electronic Publication: 2025 Nov 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Liver Cirrhosis*/drug therapy , Liver Cirrhosis*/pathology , Receptor, Angiotensin, Type 1*/metabolism , Receptor, Angiotensin, Type 1*/chemistry , Epithelial-Mesenchymal Transition*/drug effects , Triterpenes*/pharmacology , Triterpenes*/therapeutic use, Betulinic Acid ; Animals ; Pentacyclic Triterpenes/pharmacology ; Humans ; Human Umbilical Vein Endothelial Cells/drug effects ; Male ; Molecular Dynamics Simulation ; Mice, Inbred C57BL ; Mice ; Liver/pathology ; Liver/drug effects ; Endothelial-Mesenchymal Transition

Activin A-Activated ALK4 Induces Pathogenic Th17-Involved Endothelial-Mesenchymal Transition in Systemic Lupus Erythematosus-Associated Pulmonary Arterial Hypertension.

Autori: Jing S Qian J Ying H a ďalší

Zdroj: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2025 Nov; Vol. 77 (11), pp. 1533-1547. Date of Electronic Publication: 2025 Jul 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-5205 (Electronic) Linking ISSN: 23265191 NLM ISO Abbreviation: Arthritis Rheumatol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lupus Erythematosus, Systemic*/complications , Lupus Erythematosus, Systemic*/immunology , Activins*/immunology , Activins*/metabolism , Activins*/blood , Th17 Cells*/immunology , Th17 Cells*/metabolism , Pulmonary Arterial Hypertension*/immunology , Pulmonary Arterial Hypertension*/etiology , Activin Receptors, Type I*/metabolism , Activin Receptors, Type I*/immunology , Epithelial-Mesenchymal Transition*/immunology , Hypertension, Pulmonary*/immunology, Humans ; Animals ; Mice ; Interleukin-17/immunology ; Interleukin-17/blood ; Female ; Endothelial Cells/metabolism ; Adult ; Male ; Signal Transduction ; Middle Aged ; Coculture Techniques ; Endothelial-Mesenchymal Transition ; Activin Receptors, Type II

Electrodeformation of DMPC vesicle membranes near the main phase transition.

Autori: Fabiunke S Vlahovska PM

Zdroj: Biophysical journal [Biophys J] 2025 Oct 07; Vol. 124 (19), pp. 3217-3226. Date of Electronic Publication: 2025 Sep 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Dimyristoylphosphatidylcholine*/chemistry , Phase Transition* , Unilamellar Liposomes*/chemistry, Temperature ; Membrane Fluidity ; Electrodes ; Lipid Bilayers/chemistry ; Transition Temperature

Induced pluripotent stem cell-derived conditioned medium, as well as nintedanib, ameliorates bleomycin-induced pulmonary fibrosis via suppressing endothelial-mesenchymal transition.

Autori: Yu WK Yang YP Chen WC a ďalší

Zdroj: Respiratory investigation [Respir Investig] 2025 Sep; Vol. 63 (5), pp. 904-914. Date of Electronic Publication: 2025 Jul 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101581124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-5353 (Electronic) Linking ISSN: 22125345 NLM ISO Abbreviation: Respir Investig Subsets: MEDLINE

Výrazy zo slovníka MeSH: Bleomycin*/adverse effects , Indoles*/pharmacology , Indoles*/therapeutic use , Induced Pluripotent Stem Cells* , Pulmonary Fibrosis*/chemically induced , Pulmonary Fibrosis*/drug therapy , Pulmonary Fibrosis*/pathology , Pulmonary Fibrosis*/metabolism , Epithelial-Mesenchymal Transition*/drug effects , Endothelial Cells*, Animals ; Mice, Inbred C57BL ; Humans ; Culture Media, Conditioned/pharmacology ; Cadherins/metabolism ; Cells, Cultured ; Mice ; Focal Adhesion Kinase 1/metabolism ; Disease Models, Animal ; Male ; Vimentin/metabolism ; Endothelial-Mesenchymal Transition ; Antigens, CD

Ginsenoside Rb1 inhibits M1 macrophages-induced IGFBP2-mediated endothelial-mesenchymal transition to alleviate myocardial fibrosis in mice with chronic heart failure.

Autori: Jiang Y Zhao Q Zhang T a ďalší

Zdroj: In vitro cellular & developmental biology. Animal [In Vitro Cell Dev Biol Anim] 2025 Aug; Vol. 61 (7), pp. 848-861. Date of Electronic Publication: 2025 Jul 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Country of Publication: Germany NLM ID: 9418515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-706X (Electronic) Linking ISSN: 10712690 NLM ISO Abbreviation: In Vitro Cell Dev Biol Anim Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ginsenosides*/pharmacology , Ginsenosides*/therapeutic use , Macrophages*/drug effects , Macrophages*/metabolism , Macrophages*/pathology , Myocardium*/pathology , Insulin-Like Growth Factor Binding Protein 2*/metabolism , Heart Failure*/drug therapy , Heart Failure*/pathology , Heart Failure*/complications , Epithelial-Mesenchymal Transition*/drug effects, Animals ; Mice ; Fibrosis ; Male ; Endothelial Cells/drug effects ; Endothelial Cells/pathology ; Endothelial Cells/metabolism ; Chronic Disease ; Mice, Inbred C57BL ; Disease Models, Animal ; Coculture Techniques ; Endothelial-Mesenchymal Transition

Endothelial histone deacetylase 9 promotes diabetic retinopathy in mice by regulating endothelial-mesenchymal transition.

Autori: Bei Y Shen ZX Lin HR a ďalší

Zdroj: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2025 Aug; Vol. 46 (8), pp. 2213-2224. Date of Electronic Publication: 2025 Mar 31.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diabetic Retinopathy*/metabolism , Diabetic Retinopathy*/pathology , Histone Deacetylases*/metabolism , Histone Deacetylases*/genetics , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/pathology , Repressor Proteins*/metabolism , Repressor Proteins*/genetics , Endothelial Cells*/metabolism , Epithelial-Mesenchymal Transition*, Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Male ; Streptozocin ; Retina/pathology ; Retina/metabolism ; Endothelial-Mesenchymal Transition

CLCF1 contributes to high-glucose-induced EndMT by modulating JAK2/STAT3 signaling.

Autori: Deng R He K You Q a ďalší

Zdroj: European journal of medical research [Eur J Med Res] 2025 Jul 29; Vol. 30 (1), pp. 682. Date of Electronic Publication: 2025 Jul 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 9517857 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-783X (Electronic) Linking ISSN: 09492321 NLM ISO Abbreviation: Eur J Med Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: STAT3 Transcription Factor*/metabolism , Janus Kinase 2*/metabolism , Glucose*/metabolism , Glucose*/pharmacology , Epithelial-Mesenchymal Transition* , Diabetic Nephropathies*/metabolism , Diabetic Nephropathies*/pathology , Diabetic Nephropathies*/genetics , Cytokines*/metabolism , Cytokines*/genetics, Humans ; Signal Transduction ; Male ; Female ; Middle Aged ; Kidney Glomerulus/metabolism ; Kidney Glomerulus/pathology ; Endothelial Cells/metabolism ; Endothelial-Mesenchymal Transition

Loss of p300 in proximal tubular cells reduces renal fibrosis and endothelial-mesenchymal transition.

Autori: Kim H Park SY Lee SY a ďalší

Zdroj: EMBO molecular medicine [EMBO Mol Med] 2025 Jul; Vol. 17 (7), pp. 1575-1598. Date of Electronic Publication: 2025 Jul 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fibrosis*/pathology , Epithelial-Mesenchymal Transition* , E1A-Associated p300 Protein*/metabolism , E1A-Associated p300 Protein*/genetics , Kidney Tubules, Proximal*/pathology , Kidney Tubules, Proximal*/metabolism, Animals ; Humans ; Mice ; Disease Models, Animal ; Renal Insufficiency, Chronic/pathology ; Male ; Endothelial-Mesenchymal Transition

Single-Short Partial Reprogramming of the Endothelial Cells Decreases Blood Pressure via Attenuation of EndMT in Hypertensive Mice.

Autori: Pernomian L Waigi EW Nguyen V a ďalší

Zdroj: Circulation research [Circ Res] 2025 Sep 26; Vol. 137 (8), pp. 1092-1113. Date of Electronic Publication: 2025 Sep 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Hypertension*/physiopathology , Hypertension*/metabolism , Hypertension*/therapy , Hypertension*/genetics , Hypertension*/pathology , Endothelial Cells*/metabolism , Endothelial Cells*/pathology , Blood Pressure* , Cellular Reprogramming* , Epithelial-Mesenchymal Transition*, Animals ; Kruppel-Like Factor 4 ; Humans ; Mice ; Male ; Cells, Cultured ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; Mice, Inbred C57BL ; Female ; Nitric Oxide Synthase Type III/metabolism ; Nitric Oxide Synthase Type III/genetics ; Octamer Transcription Factor-3/genetics ; Octamer Transcription Factor-3/metabolism ; Disease Models, Animal ; Cell Movement ; Cell Transdifferentiation ; SOXB1 Transcription Factors/genetics ; SOXB1 Transcription Factors/metabolism ; Endothelial-Mesenchymal Transition ; Antigens, CD ; Cadherins

A disease-inspired in vitro model of aortic valve stenosis to investigate the drivers of endothelial-mesenchymal transition.

Autori: Mirzaalikhan Y Lai A Khanmohammadi M a ďalší

Zdroj: Lab on a chip [Lab Chip] 2025 Sep 09; Vol. 25 (18), pp. 4635-4649. Date of Electronic Publication: 2025 Sep 09.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101128948 Publication Model: Electronic Cited Medium: Internet ISSN: 1473-0189 (Electronic) Linking ISSN: 14730189 NLM ISO Abbreviation: Lab Chip Subsets: MEDLINE

Výrazy zo slovníka MeSH: Aortic Valve Stenosis*/pathology , Aortic Valve Stenosis*/metabolism , Epithelial-Mesenchymal Transition* , Models, Biological*, Humans ; Extracellular Matrix/metabolism ; Hyaluronic Acid/metabolism ; Hyaluronic Acid/chemistry ; Aortic Valve/pathology ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Hydrogels/chemistry ; Cells, Cultured ; Endothelial-Mesenchymal Transition ; Calcinosis

SCR Disease Name: Aortic Valve, Calcification of

Baricitinib and Infliximab Mitigate the Endothelial-to-Mesenchymal Transition (EndMT) Induced by Cytokines in HUVECs.

Autori: Barilli A Visigalli R Recchia Luciani G a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 05; Vol. 26 (17). Date of Electronic Publication: 2025 Sep 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Purines*/pharmacology , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Cytokines*/metabolism , Epithelial-Mesenchymal Transition*/drug effects , Infliximab*/pharmacology , Sulfonamides*/pharmacology , Pyrazoles*/pharmacology, Humans ; COVID-19/pathology ; COVID-19/metabolism ; SARS-CoV-2 ; Tumor Necrosis Factor-alpha/metabolism ; Spike Glycoprotein, Coronavirus/metabolism ; Macrophages/metabolism ; Macrophages/drug effects ; Macrophages/immunology ; COVID-19 Drug Treatment ; Cadherins/metabolism ; Endothelial-Mesenchymal Transition ; Azetidines

Acute Shear Stress Induces TWIST-Mediated EndMT in Venous Endothelial Cells and Human Long Saphenous Veins.

Autori: Ladak SS McQueen LW Tomkova K a ďalší

Zdroj: Cells [Cells] 2025 Sep 02; Vol. 14 (17). Date of Electronic Publication: 2025 Sep 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

Výrazy zo slovníka MeSH: Saphenous Vein*/metabolism , Saphenous Vein*/cytology , Twist-Related Protein 1*/metabolism , Stress, Mechanical* , Human Umbilical Vein Endothelial Cells*/metabolism , Epithelial-Mesenchymal Transition*/drug effects , Nuclear Proteins*/metabolism , Repressor Proteins*/metabolism, Humans ; Transforming Growth Factor beta/metabolism ; Dexamethasone/pharmacology ; Signal Transduction/drug effects ; Endothelial-Mesenchymal Transition

The antioxidant effects of decursin inhibit EndMT progression through PI3K/AKT/NF-κB and Smad signaling pathways.

Autori: Kim R Kim S Kim H a ďalší

Zdroj: BMB reports [BMB Rep] 2025 Sep; Vol. 58 (9), pp. 406-414.

Spôsob vydávania: Journal Article; News

Informácie o časopise: Publisher: Korean Society for Biochemistry and Molecular Biology Country of Publication: Korea (South) NLM ID: 101465334 Publication Model: Print Cited Medium: Internet ISSN: 1976-670X (Electronic) Linking ISSN: 19766696 NLM ISO Abbreviation: BMB Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antioxidants*/pharmacology , Benzopyrans*/pharmacology , Butyrates*/pharmacology , Epithelial-Mesenchymal Transition*/drug effects, Animals ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction/drug effects ; Mice ; Humans ; Myocardial Infarction/drug therapy ; Myocardial Infarction/metabolism ; Smad Proteins/metabolism ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Male ; Mice, Inbred C57BL ; Membrane Potential, Mitochondrial/drug effects ; Human Umbilical Vein Endothelial Cells ; Endothelial-Mesenchymal Transition