Search Results - "THERAPEUTIC use of probiotics"

Multicenter randomized controlled trial to evaluate the efficacy and safety of probiotic adjunctive therapy for children with primary hypertension.

Authors: Bidabadi, Elham Assadi, Farahnak Naghshizadian, Rama et al.

Source: Pediatric Nephrology. Dec2025, Vol. 40 Issue 12, p3707-3715. 9p.

Subject Terms: *THERAPEUTIC use of probiotics, *PATIENT compliance, *PATIENT safety, *RESEARCH funding, *HYPERTENSION, *BLIND experiment, *STATISTICAL sampling, *FISHER exact test, *MULTIPLE regression analysis, *GUT microbiota, *ANTIHYPERTENSIVE agents, *RANDOMIZED controlled trials, *CHI-squared test, *ANALYSIS of covariance, *DESCRIPTIVE statistics, *COMBINED modality therapy, *DRUG efficacy, *RESEARCH, *DATA analysis software, *DRUGS, *BLOOD pressure, *BLOOD pressure measurement, *CHILDREN

Geographic Terms: IRAN, UNITED States

Microbiota and Pancreatic Cancer: New Therapeutic Frontiers Between Engineered Microbes, Metabolites and Non-Bacterial Components.

Authors: De Lucia, Sara Sofia Nista, Enrico Celestino Candelli, Marcello et al.

Source: Cancers. Nov2025, Vol. 17 Issue 22, p3618. 23p.

Subject Terms: *THERAPEUTIC use of probiotics, *FECAL microbiota transplantation, *ANTIBIOTICS, *DIFFUSION of innovations, *DRUG resistance in cancer cells, *PATIENT safety, *IMMUNOTHERAPY, *MICROBIOTA, *FUNGI, *PANCREATIC tumors, *SYNBIOTICS, *CANCER chemotherapy, *METABOLOMICS, *PATHOGENESIS, *INFLAMMATION, *VIRUSES

The Microbiome and Genitourinary Cancers: A New Frontier.

Authors: Winslow, Timothy B. Gupta, Sophia Vaddaraju, Vedha Sai et al.

Source: Cancers. Nov2025, Vol. 17 Issue 22, p3606. 18p.

Subject Terms: *THERAPEUTIC use of probiotics, *THERAPEUTIC use of monoclonal antibodies, *KIDNEY tumors, *ANTIBIOTICS, *FECAL microbiota transplantation, *SHORT-chain fatty acids, *DRUG resistance in cancer cells, *GUT microbiota, *URINARY organs, *IMMUNOTHERAPY, *TREATMENT effectiveness, *MICROBIOTA, *IMMUNE system, *CLOSTRIDIUM, *IMMUNE checkpoint inhibitors, *RENAL cell carcinoma, *NIVOLUMAB, *PROGRESSION-free survival, BLADDER tumors, GENITOURINARY organ tumors

Efficacy of a mixture of simethicone and tyndallized bacillus coagulans in infant colic: a pilot study on behalf of Italian Society of Pediatrics (SIP).

Authors: Saviano, Michele Russo, Marina Buono, Pietro et al.

Source: Italian Journal of Pediatrics. 11/12/2025, Vol. 51 Issue 1, p1-7. 7p.

Subject Terms: *THERAPEUTIC use of probiotics, *CRYING, *BACILLUS (Bacteria), *INFANT psychology, *STATISTICAL significance, *RESEARCH funding, *CLINICAL trials, *PILOT projects, *PARENT-child relationships, *GUT microbiota, *TREATMENT effectiveness, *ORAL drug administration, *PARENT attitudes, *SEVERITY of illness index, *DESCRIPTIVE statistics, *LONGITUDINAL method, *SLEEP duration, *QUALITY of life, *SURFACE active agents, *GASTROINTESTINAL agents, *SLEEP quality, *PSYCHOLOGY of parents, *DATA analysis software, *COLIC, *SLEEP disorders, *CHILDREN

Geographic Terms: ITALY

The effect of postbiotics supplementation on obesity and metabolic health: a systematic review and meta-analysis of randomized control trials.

Authors: Li, Shuwen Sohouli, Mohammad Hassan Li, Zeli

Source: Nutrition & Metabolism. 11/13/2025, Vol. 22 Issue 1, p1-15. 15p.

Subject Terms: *THERAPEUTIC use of probiotics, *REDUCING diets, *MEDICAL information storage & retrieval systems, *TREATMENT effectiveness, *META-analysis, *DESCRIPTIVE statistics, *INSULIN, *SYSTEMATIC reviews, *MEDLINE, *WAIST circumference, *METABOLIC syndrome, *ONLINE information services, *DATA analysis software, *CONFIDENCE intervals, *ANTHROPOMETRY, *INFLAMMATION, *BLOOD pressure, *TRIGLYCERIDES, *DIETARY supplements, *SENSITIVITY & specificity (Statistics), *BIOMARKERS, *C-reactive protein

Effectiveness of probiotic supplements on cognitive function in mild cognitive impairment and Alzheimer's disease: A meta-analysis of randomized controlled trials.

Authors: Peng, Tzu-Rong Lin, Hung-Hong Tseng, Tzu-Ling et al.

Source: General Hospital Psychiatry. Nov2025, Vol. 97, p284-293. 10p.

Subject Terms: *THERAPEUTIC use of probiotics, *MEDICAL information storage & retrieval systems, *ALZHEIMER'S disease, *MILD cognitive impairment, *TREATMENT effectiveness, *META-analysis, *DESCRIPTIVE statistics, *SYSTEMATIC reviews, *MEDLINE, *MEDICAL databases, *ONLINE information services, *DATA analysis software, *CONFIDENCE intervals, *PROBIOTICS, *COGNITION

Functional and biological characterization of Lactobacillus plantarum with isatin for use as probiotics for therapeutic options.

Authors: Ravindhiran, Ramya Subramanian, Mahalakshmi Rajalingam, Madhumitha et al.

Source: Journal of Asian Natural Products Research. Nov2025, Vol. 27 Issue 11, p1673-1689. 17p.

Subject Terms: *THERAPEUTIC use of probiotics, *CENTRIFUGATION, *PHARMACEUTICAL chemistry, *NUTRITIONAL requirements, *INDOLE compounds, *ANTI-infective agents, *ESCHERICHIA coli, *LACTOBACILLUS, *ANTIOXIDANTS, *PROBIOTICS, *DRUG discovery, *PSEUDOMONAS, *KLEBSIELLA

Probiotics and Cognitive-Related Health Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses of Randomized Controlled Trials.

Authors: Liu, Xiaoxia Ning, Lianzhen Fan, Wenqi et al.

Source: Nutrition Reviews. Nov2025, Vol. 8 Issue 11, p2144-2158. 15p.

Subject Terms: *THERAPEUTIC use of probiotics, *MEDICAL information storage & retrieval systems, *LIPIDS, *TREATMENT effectiveness, *META-analysis, *OXIDATIVE stress, *DESCRIPTIVE statistics, *SYSTEMATIC reviews, *MEDLINE, *BLOOD sugar, *COGNITION disorders, *MEDICAL databases, *ONLINE information services, *INFLAMMATION, *COGNITION, *BIOMARKERS

Therapeutic Potential of Cynara scolymus Extract and Bifidobacterium longum in Alleviating Diabetes‐Induced Male Reproductive Dysfunction.

Authors: Bozorgpoursavadjani, Hadis Keyghobadi, Haniyeh Moghadam, Delaram et al.

Source: International Journal of Endocrinology. 10/19/2025, Vol. 2025, p1-17. 17p.

Subject Terms: *THERAPEUTIC use of probiotics, *DIABETES complications, *COMBINATION drug therapy, *TESTOSTERONE, *GERM cells, *COLORIMETRY, *DATA analysis, *INFERTILITY, *GLYCEMIC control, *ENZYME-linked immunosorbent assay, *REVERSE transcriptase polymerase chain reaction, *DESCRIPTIVE statistics, *MALE reproductive organ diseases, *PLANT extracts, *RATS, *BLOOD sugar, *MESSENGER RNA, *GENE expression, *DRUG efficacy, *ANIMAL experimentation, *ANTIOXIDANTS, *LUTEINIZING hormone, *FOLLICLE-stimulating hormone, *TESTIS, *ONE-way analysis of variance, *STATISTICS, *STAINS & staining (Microscopy), *DATA analysis software, *MALONDIALDEHYDE

Geographic Terms: IRAN

Lactobacillus rhamnosus Ameliorates Dyslipidemia and Liver Steatosis in a Rat Model Fed High‐Fat Diet.

Authors: Liao, Yu-Tso Huang, John Lin, Been-Ren et al.

Source: Gastroenterology Research & Practice. 10/13/2025, Vol. 2025, p1-17. 17p.

Subject Terms: *THERAPEUTIC use of probiotics, *FECAL analysis, *HYPERLIPIDEMIA treatment, *BIOLOGICAL models, *FATTY liver, *SHORT-chain fatty acids, *DATA analysis, *BODY weight, *KRUSKAL-Wallis Test, *MICROBIOTA, *DESCRIPTIVE statistics, *MANN Whitney U Test, *RATS, *RNA, *LACTOBACILLUS, *ANIMAL experimentation, *CHOLESTEROL, *STATISTICS, *LIVER, *TRIGLYCERIDES, *MICROSCOPY, *DIET

Geographic Terms: TAIWAN

Targeting Fusobacterium nucleatum in colorectal cancer: therapeutic strategies and future directions.

Authors: Kowsarkhizi, Atiyeh Sadeghi Yousefi, Bahareh Rahimi, Arian et al.

Source: Infectious Agents & Cancer. 10/14/2025, Vol. 20 Issue 1, p1-27. 27p.

Subject Terms: *THERAPEUTIC use of probiotics, *ANTIBIOTICS, *DRUG resistance in microorganisms, *GUT microbiota, *IMMUNOTHERAPY, *COLORECTAL cancer, *ANTIMICROBIAL peptides, *BIOTHERAPY, *ALTERNATIVE medicine, *GRAM-negative bacteria, *VIRUSES

High-fat diet, intestinal microecology and bone loss.

Authors: Wang, Ning Tong, Xue Li, Yi-kai

Source: Nutrition & Metabolism. 10/8/2025, Vol. 22 Issue 1, p1-23. 23p.

Subject Terms: *THERAPEUTIC use of probiotics, *OSTEOBLAST metabolism, *BONE resorption, *INTESTINAL mucosa, *SHORT-chain fatty acids, *BONE density, *GUT microbiota, *INTESTINAL barrier function, *PREBIOTICS, *EXERCISE therapy, *DIETARY fats, *OXIDATIVE stress, *INTESTINAL diseases, *OSTEOCLASTS, *INFLAMMATION, *DISEASE complications

A randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy of the synbiotic medical food, SBD111, for the clinical dietary management of bone loss in menopausal women.

Authors: Schott, Eric M. Charbonneau, Mark R. Kiel, Douglas P. et al.

Source: Osteoporosis International. Oct2025, Vol. 36 Issue 10, p2019-2030. 12p.

Subject Terms: *THERAPEUTIC use of probiotics, *OSTEOPENIA, *PATIENT safety, *BODY mass index, *BONE density, *T-test (Statistics), *RESEARCH funding, *PREBIOTICS, *STATISTICAL sampling, *BLIND experiment, *GUT microbiota, *POSTMENOPAUSE, *FUNCTIONAL foods, *RANDOMIZED controlled trials, *CHI-squared test, *DISEASES, *LONGITUDINAL method, *DRUG efficacy, *RESEARCH, *OSTEOPOROSIS, *COMPARATIVE studies, *CONFIDENCE intervals, *BIOMARKERS

Geographic Terms: AUSTRALIA

Effect of probiotics on intestinal permeability in critically ill children with sepsis: preliminary results from a double-blind, placebo-controlled trial.

Authors: Safabakhsh, Maryam Shab-Bidar, Sakineh Rohani, Pejman et al.

Source: European Journal of Nutrition. Oct2025, Vol. 64 Issue 7, p1-11. 11p.

Subject Terms: *THERAPEUTIC use of probiotics, *INFLAMMATORY mediators, *RESEARCH funding, *CARRIER proteins, *T-test (Statistics), *INTESTINAL barrier function, *STATISTICAL sampling, *BLIND experiment, *MULTIPLE organ failure, *ENZYME-linked immunosorbent assay, *FISHER exact test, *RANDOMIZED controlled trials, *HOSPITAL mortality, *DESCRIPTIVE statistics, *CHI-squared test, *MANN Whitney U Test, *ANALYSIS of covariance, *PEDIATRICS, *SEPSIS, *DRUG efficacy, *LIPOPOLYSACCHARIDES, *INTENSIVE care units, *ANALYSIS of variance, *CYTOKINES, *DATA analysis software, *CRITICALLY ill patient psychology, *INTERLEUKINS, *C-reactive protein, *DISEASE complications, *CHILDREN

Effects of Probiotics Supplementation on Short-Chain Fatty Acids: A Systematic Review of Randomized Controlled Trials.

Authors: Brasiel, Poliana Guiomar de Almeida Luquetti, Sheila Cristina Potente Dutra

Source: Nutrition Reviews. Oct2025, Vol. 8 Issue 10, p1892-1907. 16p.

Subject Terms: *THERAPEUTIC use of probiotics, *FECAL analysis, *IMMUNOGLOBULIN analysis, *MEDICAL information storage & retrieval systems, *BIFIDOBACTERIUM, *METABOLIC disorders, *ELDER care, *SHORT-chain fatty acids, *RESEARCH funding, *GUT microbiota, *FERMENTED foods, *DESCRIPTIVE statistics, *METABOLITES, *SYSTEMATIC reviews, *MEDLINE, *INFLAMMATORY bowel diseases, *INFANT formulas, *LACTOBACILLUS, *ONLINE information services, *DATA analysis software, *CHILD care, *DIETARY supplements, *GASTROINTESTINAL diseases

Treatment of Peri-implant Mucositis: An AAP/AO Systematic Review and Meta-analysis.

Authors: Guo-Hao Lin Chambrone, Leandro Rajendran, Yogalakshmi et al.

Source: International Journal of Oral & Maxillofacial Implants; 2025 Suppl 1, Vol. 40, ps49-s72, 24p

Subject Terms: THERAPEUTIC use of probiotics, STOMATITIS treatment, DENTAL implants, MEDICAL information storage & retrieval systems, OSSEOINTEGRATION, SMOKING, ELECTRONIC cigarettes, PERI-implantitis, TREATMENT effectiveness, META-analysis, DESCRIPTIVE statistics, CHI-squared test, SYSTEMATIC reviews, OPERATIVE surgery, MEDLINE, COMBINED modality therapy, LACTOBACILLUS, INFERENTIAL statistics, DEBRIDEMENT, DATA analysis software, CONFIDENCE intervals

Probiotics and inflammatory bowel disease: an umbrella meta-analysis of relapse, recurrence, and remission outcomes.

Authors: Liu, Wei Zhang, Shengbo Dong, Changzheng et al.

Source: Nutrition & Metabolism. 9/30/2025, Vol. 22 Issue 1, p1-15. 15p.

Subject Terms: *THERAPEUTIC use of probiotics, *MEDICAL information storage & retrieval systems, *EFFECT sizes (Statistics), *STATISTICAL correlation, *CROHN'S disease, *RESEARCH funding, *DISEASE remission, *TREATMENT effectiveness, *META-analysis, *ULCERATIVE colitis, *MAXIMUM likelihood statistics, *RELATIVE medical risk, *DESCRIPTIVE statistics, *INFLAMMATORY bowel diseases, *SYSTEMATIC reviews, *MEDLINE, *DRUG efficacy, *DISEASE relapse, *ONLINE information services, *TREATMENT effect heterogeneity, *QUALITY assurance, *CONFIDENCE intervals, *DATA analysis software, *DIETARY supplements, *PUBLICATION bias, *EVALUATION

Effect of Lactobacillus spp. Supplementation for Improving Muscle Health: A Systematic Review and Meta-Analysis.

Authors: Im, Jeong Yeon Jung, Eun Jin Lee, Jun Gu et al.

Source: Journal of Medicinal Food. Sep2025, Vol. 28 Issue 9, p842-859. 18p.

Subject Terms: *THERAPEUTIC use of probiotics, *SKELETAL muscle physiology, *MEDICAL information storage & retrieval systems, *RESEARCH funding, *META-analysis, *DESCRIPTIVE statistics, *SYSTEMATIC reviews, *MEDLINE, *MUSCLE strength, *LEAN body mass, *LACTOBACILLUS, *DRUG efficacy, *MEDICAL databases, *MUSCULAR atrophy, *PROBIOTICS, *ONLINE information services, *CONFIDENCE intervals, *GRIP strength, *DIETARY supplements, *SARCOPENIA

Efficacy of a Probiotic Combination on Glycemic Index and Insulin Resistance in Adults: A Systematic Review and Meta-Analysis.

Authors: Dubey, Vishal P. Kansagra, Jignesh J. Sureja, Varun P. et al.

Source: Journal of Dietary Supplements. 2025, Vol. 22 Issue 5, p641-663. 23p.

Subject Terms: *THERAPEUTIC use of probiotics, *BIFIDOBACTERIUM, *INSULIN sensitivity, *GUT microbiota, *PANCREATIC beta cells, *TREATMENT effectiveness, *META-analysis, *DESCRIPTIVE statistics, *INSULIN resistance, *SYSTEMATIC reviews, *BLOOD sugar, *LACTOBACILLUS acidophilus, *LACTOBACILLUS, *GLYCEMIC index, *DIETARY supplements

The role of the microbiome in endometrial carcinoma: Pathogenesis, biomarkers, and therapeutic prospects.

Authors: Abdalla, Wafa Ibrahim, Wisam Nabeel Abdallah, Atiyeh M. et al.

Source: Journal of Obstetrics & Gynaecology Research. Sep2025, Vol. 51 Issue 9, p1-16. 16p.

Subject Terms: *THERAPEUTIC use of probiotics, *RISK assessment, *PREDICTION models, *HEALTH, *CELL physiology, *IMMUNOTHERAPY, *MICROBIOTA, *TUMOR markers, *INFORMATION resources, *ESTROGEN, *IMMUNE system, *ENDOMETRIAL tumors, *CHRONIC diseases, *CELL lines, *CANCER chemotherapy, *METABOLITES, *ENVIRONMENTAL exposure, *INFLAMMATION, *MOLECULAR biology, *DISEASE progression, *DIET, *DISEASE risk factors