Suchergebnisse - "Superoxide Dismutase-1: genetics"

Inflammation-dependent oxidative stress metabolites as a hallmark of amyotrophic lateral sclerosis

Autoren: Luyang Xiong Michael McCoy Hitoshi Komuro et al.

Quelle: Free Radical Biology and Medicine. 178:125-133

Schlagwörter: 0301 basic medicine, mice, Mice, Transgenic, Mice, 03 medical and health sciences, Superoxide Dismutase-1, oxidative stress, Animals, Humans, animal, neurodegenerative diseases, humans, inflammation (genetics), transgenic, Inflammation, superoxide dismutase (metabolism), 0303 health sciences, disease models, amyotrophic lateral sclerosis (genetics), Superoxide Dismutase, Amyotrophic Lateral Sclerosis, Biomedical Sciences, lipid peroxidation, Neurodegenerative Diseases, carboxyethylpyrrole, 3. Good health, animals, Disease Models, Animal, Oxidative Stress, Mutation, superoxide dismutase-1 (genetics), biomarker, mutation

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/34871763

Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS

Autoren: Aly, Amr Laszlo, Zsofia I. Barletta, Francesca et al.

Quelle: Acta neuropathologica -, - (2023). doi:10.1007/s00401-023-02611-y

Schlagwörter: info:eu-repo/classification/ddc/610, Humans, Amyotrophic Lateral Sclerosis: pathology, Neurodegenerative Diseases: pathology, Proteomics, Superoxide Dismutase-1: genetics, Motor Neurons: metabolism

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:37488208; info:eu-repo/semantics/altIdentifier/issn/1432-0533; info:eu-repo/semantics/altIdentifier/issn/0001-6322; https://pub.dzne.de/record/259239

Verfügbarkeit: https://pub.dzne.de/record/259239
https://pub.dzne.de/search?p=id:%22DZNE-2023-00740%22

Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis.

Autoren: Catanese, Alberto Rajkumar, Sandeep Mulaw, Medhanie et al.

Quelle: Brain 146(9), 3770 - 3782 (2023). doi:10.1093/brain/awad075

Schlagwörter: info:eu-repo/classification/ddc/610, Humans, Amyotrophic Lateral Sclerosis: metabolism, Multiomics, Neurodegenerative Diseases: metabolism, C9orf72 Protein: genetics, Superoxide Dismutase-1: genetics, Induced Pluripotent Stem Cells: metabolism, Motor Neurons: metabolism, ALS, deep learning, motor neurons, omics

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/1460-2156; info:eu-repo/semantics/altIdentifier/issn/0006-8950; info:eu-repo/semantics/altIdentifier/pmid/pmid:36883643; https://pub.dzne.de/record/258910

Verfügbarkeit: https://pub.dzne.de/record/258910
https://pub.dzne.de/search?p=id:%22DZNE-2023-00683%22

Presymptomatic grey matter alterations in ALS kindreds: a computational neuroimaging study of asymptomatic C9orf72 and SOD1 mutation carriers.

Autoren: Bede, Peter Lulé, Dorothée Müller, Hans-Peter et al.

Quelle: Journal of neurology 270(9), 4235-4247 (2023). doi:10.1007/s00415-023-11764-5

Schlagwörter: info:eu-repo/classification/ddc/610, Humans, Amyotrophic Lateral Sclerosis: diagnostic imaging, Amyotrophic Lateral Sclerosis: genetics, Bayes Theorem, C9orf72 Protein: genetics, Frontotemporal Dementia: genetics, Gray Matter: diagnostic imaging, Magnetic Resonance Imaging, Mutation, Neuroimaging, Prospective Studies, Superoxide Dismutase-1: genetics, Amyotrophic lateral sclerosis, Asymptomatic, Biomarker, C9orf72, Frontotemporal dementia, Magnetic resonance imaging (MRI), Pharmaceutical trials, Presymptomatic, SOD1

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/0340-5354; info:eu-repo/semantics/altIdentifier/issn/0367-004X; info:eu-repo/semantics/altIdentifier/issn/1432-1459; info:eu-repo/semantics/altIdentifier/pmid/pmid:37178170; info:eu-repo/semantics/altIdentifier/issn/0012-1037; https://pub.dzne.de/record/258909

Verfügbarkeit: https://pub.dzne.de/record/258909
https://pub.dzne.de/search?p=id:%22DZNE-2023-00682%22

Neurofilament light-chain response during therapy with antisense oligonucleotide tofersen in SOD1-related ALS: Treatment experience in clinical practice.

Autoren: Meyer, Thomas Schumann, Peggy Kolzarek, Felix et al.

Quelle: Muscle & nerve 67(6), 515 - 521 (2023). doi:10.1002/mus.27818

Schlagwörter: info:eu-repo/classification/ddc/610, Humans, Amyotrophic Lateral Sclerosis: drug therapy, Amyotrophic Lateral Sclerosis: genetics, Oligonucleotides, Antisense: therapeutic use, Superoxide Dismutase-1: genetics, Intermediate Filaments, Biomarkers, Neurofilament Proteins, amyotrophic lateral sclerosis, neurofilament light chain, tofersen

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/1097-4598; info:eu-repo/semantics/altIdentifier/issn/0148-639X; info:eu-repo/semantics/altIdentifier/pmid/pmid:36928619; https://pub.dzne.de/record/257590

Verfügbarkeit: https://pub.dzne.de/record/257590
https://pub.dzne.de/search?p=id:%22DZNE-2023-00466%22

A novel homozygous p.Ser69Pro SOD1 mutation causes severe young-onset ALS with decreased enzyme activity.

Autoren: Fahmy, Nagia Müller, Kathrin Andersen, Peter Munch et al.

Quelle: Journal of neurology 270(3), 1770-1773 (2022). doi:10.1007/s00415-022-11489-x

Schlagwörter: info:eu-repo/classification/ddc/610, Humans, Superoxide Dismutase-1: genetics, Amyotrophic Lateral Sclerosis: genetics, Amyotrophic Lateral Sclerosis: diagnosis, Mutation, Homozygote, Motor Neurons, Superoxide Dismutase: genetics, Enzyme activity, Homozygous, Novel mutation, SOD1, Young-onset

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/0939-1517; info:eu-repo/semantics/altIdentifier/issn/1432-1459; info:eu-repo/semantics/altIdentifier/issn/0340-5354; info:eu-repo/semantics/altIdentifier/issn/0367-004X; info:eu-repo/semantics/altIdentifier/pmid/pmid:36472686; info:eu-repo/semantics/altIdentifier/issn/1619-800X; info:eu-repo/semantics/altIdentifier/issn/0012-1037; https://pub.dzne.de/record/169125

Verfügbarkeit: https://pub.dzne.de/record/169125
https://pub.dzne.de/search?p=id:%22DZNE-2023-00004%22

Mutation-specific metabolic profiles in presymptomatic amyotrophic lateral sclerosis.

Autoren: Xia, Kailin Witzel, Simon Witzel, Christina et al.

Quelle: European journal of neurology 30(1), 87-95 (2022). doi:10.1111/ene.15584

Schlagwörter: info:eu-repo/classification/ddc/610, Humans, Amyotrophic Lateral Sclerosis: genetics, Superoxide Dismutase-1: genetics, Blood Glucose, Disease Progression, Metabolome, Amyotrophic lateral sclerosis, Genetics, Metabolism, Presymptomatic Gene Carriers

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/1471-0552; info:eu-repo/semantics/altIdentifier/pmid/pmid:36169607; info:eu-repo/semantics/altIdentifier/issn/1468-1331; info:eu-repo/semantics/altIdentifier/issn/1351-5101; https://pub.dzne.de/record/165272

Verfügbarkeit: https://pub.dzne.de/record/165272
https://pub.dzne.de/search?p=id:%22DZNE-2022-01565%22

Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.

Autoren: Yazar, Volkan Kühlwein, Julia Knehr, Antje et al.

Quelle: Scientific reports 13(1), 12019 (2023). doi:10.1038/s41598-023-38684-8

Schlagwörter: info:eu-repo/classification/ddc/600, Animals, Mice, Amyotrophic Lateral Sclerosis: genetics, Amyotrophic Lateral Sclerosis: metabolism, Leukocytes, Mononuclear: metabolism, Transgenic, Mutation, Superoxide Dismutase: genetics, Superoxide Dismutase: metabolism, Superoxide Dismutase-1: genetics

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:37491426; info:eu-repo/semantics/altIdentifier/issn/2045-2322; https://pub.dzne.de/record/259245

Verfügbarkeit: https://pub.dzne.de/record/259245
https://pub.dzne.de/search?p=id:%22DZNE-2023-00746%22

Metabolic alterations precede neurofilament changes in presymptomatic ALS gene carriers.

Autoren: Dorst, Johannes Weydt, Patrick Müller, Kathrin et al.

Quelle: EBioMedicine 90, 104521 (2023). doi:10.1016/j.ebiom.2023.104521

Schlagwörter: info:eu-repo/classification/ddc/610, Humans, Male, Adult, Middle Aged, Female, Amyotrophic Lateral Sclerosis: diagnosis, Amyotrophic Lateral Sclerosis: genetics, Intermediate Filaments, C9orf72 Protein: genetics, Superoxide Dismutase-1: genetics, Biomarkers, Amyotrophic lateral sclerosis, Metabolic, Metabolism, Mutations carriers, Presymptomatic

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/2352-3964; info:eu-repo/semantics/altIdentifier/pmid/pmid:36917918; https://pub.dzne.de/record/257342

Verfügbarkeit: https://pub.dzne.de/record/257342
https://pub.dzne.de/search?p=id:%22DZNE-2023-00411%22

Downstream Effects of Mutations in SOD1 and TARDBP Converge on Gene Expression Impairment in Patient-Derived Motor Neurons.

Autoren: Dash, Banaja Freischmidt, Axel Weishaupt, Jochen H et al.

Quelle: International journal of molecular sciences 23(17), 9652 (2022). doi:10.3390/ijms23179652 special issue: "Neurological Diseases: A Molecular Genetic Perspective"

Schlagwörter: info:eu-repo/classification/ddc/540, Amyotrophic Lateral Sclerosis: genetics, DNA-Binding Proteins: genetics, DNA-Binding Proteins: metabolism, Gene Expression, Humans, Induced Pluripotent Stem Cells: metabolism, Motor Neurons: metabolism, Mutation, Neurodegenerative Diseases: metabolism, RNA: metabolism, Superoxide Dismutase-1: genetics, RNA sequencing (RNA-Seq), amyotrophic lateral sclerosis (ALS), differentially expressed genes (DEG), human induced pluripotent stem cells (iPSC), motor neurons (MN), protein-protein interaction (PPI), DNA-Binding Proteins, SOD1 protein, human, TARDBP protein, RNA, Superoxide Dismutase-1

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:36077049; info:eu-repo/semantics/altIdentifier/issn/1422-0067; info:eu-repo/semantics/altIdentifier/issn/1661-6596; https://pub.dzne.de/record/165289

Verfügbarkeit: https://pub.dzne.de/record/165289
https://pub.dzne.de/search?p=id:%22DZNE-2022-01582%22

Role of genetics in amyotrophic lateral sclerosis: a large cohort study in Chinese mainland population.

Autoren: Chen, Yong-Ping Yu, Shi-Hui Liu, Fei-Fei et al.

Quelle: Journal of medical genetics 59(9), 840-849 (2022). doi:10.1136/jmedgenet-2021-107965

Schlagwörter: info:eu-repo/classification/ddc/610, Amyotrophic Lateral Sclerosis: epidemiology, Amyotrophic Lateral Sclerosis: genetics, C9orf72 Protein: genetics, Cohort Studies, Genetic Predisposition to Disease, Humans, Mutation: genetics, Superoxide Dismutase-1: genetics, genetic variation, genetics, medical, neurodegenerative diseases

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:34544842; info:eu-repo/semantics/altIdentifier/issn/0022-2593; info:eu-repo/semantics/altIdentifier/issn/1468-6244; https://pub.dzne.de/record/164181

Verfügbarkeit: https://pub.dzne.de/record/164181
https://pub.dzne.de/search?p=id:%22DZNE-2022-00837%22

Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS

Autoren: Günther, René Pal, Arun Marklund, Stefan L. et al.

Quelle: Cells 11(7), 1246 (2022). doi:10.3390/cells11071246 special issue: "Neurodegenerative and Neurologic Disease: Genes, Mechanisms, and Therapies"

Schlagwörter: info:eu-repo/classification/ddc/570, Amyotrophic Lateral Sclerosis: metabolism, Humans, Induced Pluripotent Stem Cells: metabolism, Mitochondria: metabolism, Superoxide Dismutase-1: genetics, Superoxide Dismutase-1: metabolism

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/2073-4409; info:eu-repo/semantics/altIdentifier/pmid/pmid:35406813; https://pub.dzne.de/record/163726

Verfügbarkeit: https://pub.dzne.de/record/163726
https://pub.dzne.de/search?p=id:%22DZNE-2022-00465%22

The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration

Autoren: Opie-Martin, Sarah Iacoangeli, Alfredo Topp, Simon, D et al.

Weitere Verfasser: Opie-Martin, Sarah Iacoangeli, Alfredo Topp, Simon, D et al.

Quelle: ISSN: 2041-1723.

Schlagwörter: MESH: Humans, MESH: Mutation, MESH: Amyotrophic Lateral Sclerosis / epidemiology, MESH: Amyotrophic Lateral Sclerosis / genetics, MESH: Phenotype Superoxide Dismutase / genetics, MESH: Superoxide Dismutase-1 / genetics, [SCCO.NEUR]Cognitive science/Neuroscience, [SDV.GEN]Life Sciences [q-bio]/Genetics

Relation: info:eu-repo/semantics/altIdentifier/pmid/36371497; hal-04312742; https://hal.umontpellier.fr/hal-04312742; https://hal.umontpellier.fr/hal-04312742/document; https://hal.umontpellier.fr/hal-04312742/file/41467_2022_Article_34620.pdf; PUBMED: 36371497; PUBMEDCENTRAL: PMC9653399

Verfügbarkeit: https://hal.umontpellier.fr/hal-04312742
https://hal.umontpellier.fr/hal-04312742/document
https://hal.umontpellier.fr/hal-04312742/file/41467_2022_Article_34620.pdf
https://doi.org/10.1038/s41467-022-34620-y

A selectable all-in-one CRISPR prime editing piggyBac transposon allows for highly efficient gene editing in human cell lines.

Autoren: Eggenschwiler, Reto Gschwendtberger, Thomas Martin, Ulrich et al.

Quelle: Scientific reports 11(1), 22154 (2021). doi:10.1038/s41598-021-01689-2

Schlagwörter: info:eu-repo/classification/ddc/600, Amyotrophic Lateral Sclerosis: genetics, CRISPR-Cas Systems, Cell Line, Gene Editing: methods, HEK293 Cells, Humans, Induced Pluripotent Stem Cells: metabolism, Mutation, Superoxide Dismutase-1: genetics, Transfection: methods, Superoxide Dismutase-1

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:34773059; info:eu-repo/semantics/altIdentifier/issn/2045-2322; https://pub.dzne.de/record/163639

Verfügbarkeit: https://pub.dzne.de/record/163639
https://pub.dzne.de/search?p=id:%22DZNE-2022-00385%22

Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients.

Autoren: Bayer, David Antonucci, Stefano Müller, Hans-Peter et al.

Quelle: Translational neurodegeneration 10(1), 17 (2021). doi:10.1186/s40035-021-00241-6

Schlagwörter: info:eu-repo/classification/ddc/570, Amyotrophic Lateral Sclerosis: diagnostic imaging, Amyotrophic Lateral Sclerosis: pathology, Animals, Brain Mapping, Case-Control Studies, Cohort Studies, Diffusion Tensor Imaging, Energy Metabolism, Humans, Hypothalamus: diagnostic imaging, Hypothalamus: pathology, Immunohistochemistry, Mice, Motor Cortex: growth & development, Motor Cortex: pathology, Neural Pathways: diagnostic imaging, Neural Pathways: pathology, Prefrontal Cortex: diagnostic imaging, Prefrontal Cortex: pathology, RNA-Binding Protein FUS: genetics, Superoxide Dismutase-1: genetics, Agranular insula, Amyotrophic lateral sclerosis, Hypermetabolism, Lateral hypothalamus, Orbitofrontal cortex, rAAV2

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:34059131; info:eu-repo/semantics/altIdentifier/issn/2096-6466; info:eu-repo/semantics/altIdentifier/issn/2047-9158; https://pub.dzne.de/record/162632

Verfügbarkeit: https://pub.dzne.de/record/162632
https://pub.dzne.de/search?p=id:%22DZNE-2021-01328%22

A natural history comparison of SOD1-mutant patients with amyotrophic lateral sclerosis between Chinese and German populations.

Autoren: Tang, Lu Dorst, Johannes Fan, Dongsheng et al.

Quelle: Translational neurodegeneration 10, 42 (2021). doi:10.1186/s40035-021-00266-x

Schlagwörter: info:eu-repo/classification/ddc/570, Amyotrophic Lateral Sclerosis: diagnosis, Amyotrophic Lateral Sclerosis: epidemiology, Amyotrophic Lateral Sclerosis: genetics, China: epidemiology, Germany, Humans, Mutation: genetics, Superoxide Dismutase: genetics, Superoxide Dismutase-1: genetics

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:34711284; info:eu-repo/semantics/altIdentifier/issn/2096-6466; info:eu-repo/semantics/altIdentifier/issn/2047-9158; https://pub.dzne.de/record/162640

Verfügbarkeit: https://pub.dzne.de/record/162640
https://pub.dzne.de/search?p=id:%22DZNE-2021-01336%22

Blocking glutamate mGlu5 receptors with the negative allosteric modulator CTEP improves disease course in SOD1G93A mouse model of amyotrophic lateral sclerosis.

Autoren: Milanese, Marco Bonifacino, Tiziana Bertola, Nadia et al.

Quelle: British journal of pharmacology 178(18), 3747-3764 (2021). doi:10.1111/bph.15515

Schlagwörter: info:eu-repo/classification/ddc/610, Amyotrophic Lateral Sclerosis: drug therapy, Animals, Disease Models, Animal, Disease Progression, Female, Glutamic Acid, Male, Mice, Transgenic, Receptor, Metabotropic Glutamate 5, Spinal Cord, Superoxide Dismutase, Superoxide Dismutase-1: genetics, 2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine (CTEP), SOD1G93A mice, amyotrophic lateral sclerosis (ALS), in vivo pharmacological treatment, metabotropic glutamate receptor 5 (mGlu5 receptor)

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:33931856; info:eu-repo/semantics/altIdentifier/issn/2056-8177; info:eu-repo/semantics/altIdentifier/issn/1476-5381; info:eu-repo/semantics/altIdentifier/issn/0007-1188; info:eu-repo/semantics/altIdentifier/issn/0366-0826; https://pub.dzne.de/record/155465

Verfügbarkeit: https://pub.dzne.de/record/155465
https://pub.dzne.de/search?p=id:%22DZNE-2021-00664%22

UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy

Autoren: Min Ji Yoon Boyoon Choi Eun Jin Kim et al.

Weitere Verfasser: Min Ji Yoon Boyoon Choi Eun Jin Kim et al.

Quelle: Nat Commun
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Schlagwörter: 0301 basic medicine, Autophagy / genetics, Sequestosome-1 Protein / genetics, Protein Folding, Green Fluorescent Proteins / metabolism, Proteasome Endopeptidase Complex / drug effects, Cell Cycle Proteins / genetics, Leupeptins, Cell Cycle Proteins, Motor Neurons / drug effects, Motor Neurons / metabolism, Xenopus laevis, Superoxide Dismutase-1 / metabolism, Genes, Reporter, Ganglia, Spinal, Sequestosome-1 Protein, Molecular Chaperones / genetics, Transgenes, 10. No inequality, Motor Neurons, 0303 health sciences, Spinal / metabolism, Motor Neurons / cytology, Luminescent Proteins / metabolism, Sequestosome-1 Protein / metabolism, 3. Good health, Superoxide Dismutase-1 / genetics, Protein Folding / drug effects, Spinal / cytology, Signal Transduction, Proteasome Endopeptidase Complex, Science, Green Fluorescent Proteins, Primary Cell Culture, Cell Cycle Proteins / metabolism, Leupeptins / pharmacology, Article, Protein Aggregates, 03 medical and health sciences, Green Fluorescent Proteins / genetics, Protein Aggregates* / drug effects, Autophagy / drug effects, Autophagy, Luminescent Proteins / genetics, Animals, Humans, Reporter, Molecular Chaperones / metabolism, Proteasome Endopeptidase Complex / metabolism, Luminescent Proteins, HEK293 Cells, Genes, Gene Expression Regulation, Ganglia, HeLa Cells, Molecular Chaperones

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.nature.com/articles/s41467-021-22252-7.pdf
https://pubmed.ncbi.nlm.nih.gov/33782410
https://doaj.org/article/f97d34af557c40b1a93c7c19606cff1c
https://www.nature.com/articles/s41467-021-22252-7
https://ir.ymlib.yonsei.ac.kr/handle/22282913/182451
https://ir.ymlib.yonsei.ac.kr/bitstream/22282913/182451/1/T202101286.pdf
http://ui.adsabs.harvard.edu/abs/2021NatCo..12.1955Y/abstract
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007730
https://koreauniv.pure.elsevier.com/en/publications/uxt-chaperone-prevents-proteotoxicity-by-acting-as-an-autophagy-a

CRISPR/Cas9-Mediated Gene Correction to Understand ALS

Weitere Verfasser: Yeomin Yun Yoon Ha Ha, Yoon

Schlagwörter: Amyotrophic Lateral Sclerosis / genetics, Amyotrophic Lateral Sclerosis / therapy, Animals, C9orf72 Protein / genetics, CRISPR-Cas Systems, DNA-Binding Proteins / genetics, Humans, RNA-Binding Protein FUS / genetics, Superoxide Dismutase-1 / genetics, Targeted Gene Repair / methods, CRISPR/Cas9, amyotrophic lateral sclerosis (ALS), gene correction, induced pluripotent stem cells (iPSCs)

Relation: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; J01133; https://ir.ymlib.yonsei.ac.kr/handle/22282913/182642; T202006410

Verfügbarkeit: https://ir.ymlib.yonsei.ac.kr/handle/22282913/182642
https://doi.org/10.3390/ijms21113801

Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

Autoren: Ouali Alami, Najwa Tang, Linyun Böckers, Tobias et al.

Quelle: Life science alliance 3(11), e201900571 (2020). doi:10.26508/lsa.201900571

Schlagwörter: info:eu-repo/classification/ddc/570, Amyotrophic Lateral Sclerosis: blood, Amyotrophic Lateral Sclerosis: metabolism, Animals, Astrocytes: metabolism, Astrocytes: physiology, Disease Models, Animal, Disease Progression, Female, Humans, Male, Mice, Inbred C57BL, Transgenic, Motor Neurons: metabolism, Motor Neurons: physiology, Spinal Cord: metabolism, Spine: blood supply, Spine: metabolism, Superoxide Dismutase: metabolism, Superoxide Dismutase-1: genetics, Superoxide Dismutase-1: metabolism, Wnt Proteins: metabolism, Wnt-5a Protein: metabolism

Geographisches Schlagwort: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:32900826; info:eu-repo/semantics/altIdentifier/issn/2575-1077; https://pub.dzne.de/record/164314

Verfügbarkeit: https://pub.dzne.de/record/164314
https://pub.dzne.de/search?p=id:%22DZNE-2022-00968%22