Suchergebnisse - "Sulfonamides"

Rational Design and Antimycobacterial Evaluation of Aryl Sulfonamide-Linked Isoniazid Hydrazones Against Mycobacterium Tuberculosis.

Autoren: Kadima MG Mishra S Kumar G et al.

Quelle: ChemMedChem [ChemMedChem] 2025 Nov 06; Vol. 20 (21), pp. e202500398. Date of Electronic Publication: 2025 Sep 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

MeSH-Schlagworte: Mycobacterium tuberculosis*/drug effects , Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemistry , Antitubercular Agents*/chemical synthesis , Isoniazid*/chemistry , Isoniazid*/pharmacology , Sulfonamides*/chemistry , Sulfonamides*/pharmacology , Hydrazones*/chemistry , Hydrazones*/pharmacology , Hydrazones*/chemical synthesis , Drug Design*, Microbial Sensitivity Tests ; Humans ; Structure-Activity Relationship ; Molecular Docking Simulation ; Molecular Structure ; Dose-Response Relationship, Drug

Coumarin-Containing Aromatic Sulfonamides With Carbonic Anhydrase Inhibitory Properties Against Human and Fungal Isoforms.

Autoren: Angeli A Petrou A Kartsev V et al.

Quelle: Chemical biology & drug design [Chem Biol Drug Des] 2025 Nov; Vol. 106 (5), pp. e70188.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE

MeSH-Schlagworte: Carbonic Anhydrase Inhibitors*/chemistry , Carbonic Anhydrase Inhibitors*/pharmacology , Carbonic Anhydrase Inhibitors*/metabolism , Carbonic Anhydrases*/metabolism , Carbonic Anhydrases*/chemistry , Coumarins*/chemistry , Coumarins*/pharmacology , Sulfonamides*/chemistry , Sulfonamides*/pharmacology , Sulfonamides*/metabolism, Humans ; Carbonic Anhydrase I/metabolism ; Carbonic Anhydrase I/antagonists & inhibitors ; Carbonic Anhydrase II/metabolism ; Carbonic Anhydrase II/antagonists & inhibitors ; Catalytic Domain ; Isoenzymes/metabolism ; Isoenzymes/antagonists & inhibitors ; Malassezia/enzymology ; Malassezia/drug effects ; Molecular Docking Simulation ; Structure-Activity Relationship ; Fungal Proteins/chemistry

Environmentally friendly determination of sulfonamides in honey samples: Hydrophobic natural deep eutectic solvent-based microextraction prior to high-performance liquid chromatography by matrix matching calibration techniques.

Autoren: Erim ÜC; Istanbul Medipol University, School of Pharmacy, Department of Analytical Chemistry, 34810 Istanbul, Turkey. Electronic address: uc.erim@gmail.com.

Quelle: Food chemistry [Food Chem] 2025 Oct 15; Vol. 489, pp. 144996. Date of Electronic Publication: 2025 Jun 01.

Publikationsart: Journal Article; Evaluation Study

Info zur Zeitschrift: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH-Schlagworte: Honey*/analysis , Sulfonamides*/isolation & purification , Sulfonamides*/analysis , Liquid Phase Microextraction*/methods , Anti-Bacterial Agents*/isolation & purification , Anti-Bacterial Agents*/analysis, Chromatography, High Pressure Liquid/methods ; Chromatography, High Pressure Liquid/standards ; Food Contamination/analysis ; Hydrophobic and Hydrophilic Interactions ; Calibration ; Deep Eutectic Solvents/chemistry ; Limit of Detection

Sulfonamide Inhibitors of Amyloid Aggregation: A Promising Path against Neurodegenerative Diseases.

Autoren: Smirnovienė J Matulis D

Quelle: ChemMedChem [ChemMedChem] 2025 Oct 06; Vol. 20 (19), pp. e202500324. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

MeSH-Schlagworte: Neurodegenerative Diseases*/drug therapy , Neurodegenerative Diseases*/metabolism , Sulfonamides*/chemistry , Sulfonamides*/pharmacology , Sulfonamides*/therapeutic use , Amyloid*/antagonists & inhibitors , Amyloid*/metabolism , Protein Aggregation, Pathological*/drug therapy , Protein Aggregation, Pathological*/metabolism , Amyloidogenic Proteins*/antagonists & inhibitors , Amyloidogenic Proteins*/metabolism, Humans ; Protein Aggregates/drug effects ; Animals ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Peptides/antagonists & inhibitors ; Molecular Structure

Synthesis of novel benzene bissulfonamides with carbonic anhydrase and choline esterase inhibitory properties.

Autoren: Canoğlu U Akıncıoğlu A Öztaşkın N et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108938. Date of Electronic Publication: 2025 Aug 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Carbonic Anhydrase Inhibitors*/chemical synthesis , Carbonic Anhydrase Inhibitors*/pharmacology , Carbonic Anhydrase Inhibitors*/chemistry , Cholinesterase Inhibitors*/chemical synthesis , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Butyrylcholinesterase*/metabolism , Acetylcholinesterase*/metabolism , Sulfonamides*/chemical synthesis , Sulfonamides*/pharmacology , Sulfonamides*/chemistry , Carbonic Anhydrase I*/metabolism , Carbonic Anhydrase I*/antagonists & inhibitors, Humans ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Carbonic Anhydrase II/antagonists & inhibitors ; Carbonic Anhydrase II/metabolism ; Molecular Docking Simulation

Based on magnetically recoverable catalysts: a green strategy to sulfonamides.

Autoren: Song C Kazemi M

Quelle: Molecular diversity [Mol Divers] 2025 Oct; Vol. 29 (5), pp. 5045-5074. Date of Electronic Publication: 2024 Nov 04.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

MeSH-Schlagworte: Sulfonamides*/chemistry , Sulfonamides*/chemical synthesis , Green Chemistry Technology*/methods , Magnetite Nanoparticles*/chemistry, Catalysis

Potential therapeutic GSK-3β inhibitor 9-ING-41 is active in combination with venetoclax in double-hit lymphoma (DHL).

Autoren: Lei H Zhang Y Zheng H et al.

Quelle: Cancer biology & therapy [Cancer Biol Ther] 2025 Dec 31; Vol. 26 (1), pp. 2581831. Date of Electronic Publication: 2025 Nov 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137842 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8576 (Electronic) Linking ISSN: 15384047 NLM ISO Abbreviation: Cancer Biol Ther Subsets: MEDLINE

MeSH-Schlagworte: Sulfonamides*/pharmacology , Sulfonamides*/therapeutic use , Bridged Bicyclo Compounds, Heterocyclic*/pharmacology , Bridged Bicyclo Compounds, Heterocyclic*/therapeutic use , Glycogen Synthase Kinase 3 beta*/antagonists & inhibitors , Antineoplastic Combined Chemotherapy Protocols*/pharmacology , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Lymphoma*/drug therapy , Lymphoma*/pathology , Lymphoma*/genetics, Humans ; Cell Line, Tumor ; Apoptosis/drug effects ; Cell Proliferation/drug effects ; Drug Synergism ; Cell Survival/drug effects

4-substituted (1,2,5-oxadiazol-3-yl)benzamides and -benzene sulfonamides as antiplasmodial agents.

Autoren: Hermann T Hochegger P Saf R et al.

Quelle: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118150. Date of Electronic Publication: 2025 Sep 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Antimalarials*/pharmacology , Antimalarials*/chemistry , Antimalarials*/chemical synthesis , Plasmodium falciparum*/drug effects , Sulfonamides*/pharmacology , Sulfonamides*/chemistry , Sulfonamides*/chemical synthesis , Benzamides*/pharmacology , Benzamides*/chemistry , Benzamides*/chemical synthesis , Oxadiazoles*/pharmacology , Oxadiazoles*/chemistry , Oxadiazoles*/chemical synthesis, Structure-Activity Relationship ; Rats ; Animals ; Molecular Structure ; Parasitic Sensitivity Tests ; Dose-Response Relationship, Drug ; Humans

The Time Course of Repolarization Effects of Intravenous Dofetilide: A Pure Class III Antiarrhythmic Agent.

Autoren: Molnar J Somberg JC

Quelle: The American journal of cardiology [Am J Cardiol] 2025 Dec 15; Vol. 257, pp. 38-42. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 0207277 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1913 (Electronic) Linking ISSN: 00029149 NLM ISO Abbreviation: Am J Cardiol Subsets: MEDLINE

MeSH-Schlagworte: Phenethylamines*/administration & dosage , Phenethylamines*/pharmacokinetics , Sulfonamides*/administration & dosage , Sulfonamides*/pharmacokinetics , Anti-Arrhythmia Agents*/administration & dosage , Anti-Arrhythmia Agents*/pharmacokinetics , Heart Rate*/drug effects, Humans ; Adult ; Male ; Female ; Middle Aged ; Young Adult ; Infusions, Intravenous ; Adolescent ; Electrocardiography/drug effects ; Electrocardiography, Ambulatory ; Time Factors ; Long QT Syndrome ; Dose-Response Relationship, Drug ; Healthy Volunteers ; Potassium Channel Blockers/administration & dosage

Synthesis, in vitro and in silico anticancer evaluations of novel styryl 1,3,4-oxadiazole-sulfonamide hybrids for colorectal cancer.

Autoren: Ahmed HI Yazıcı OC Abdullah FO et al.

Quelle: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2025 Dec 15; Vol. 131, pp. 118409. Date of Electronic Publication: 2025 Sep 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Oxadiazoles*/chemistry , Oxadiazoles*/pharmacology , Oxadiazoles*/chemical synthesis , Sulfonamides*/chemistry , Sulfonamides*/pharmacology , Sulfonamides*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/pathology, Humans ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Molecular Docking Simulation ; Structure-Activity Relationship ; Cell Line, Tumor ; Molecular Structure ; Dose-Response Relationship, Drug ; HCT116 Cells

Design, synthesis, structure-activity relationship (SAR) and analgesic effect studies of novel arylsulfonamides as selective Nav1.7 inhibitors.

Autoren: Wu R Chen W Wang X et al.

Quelle: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 05; Vol. 299, pp. 118069. Date of Electronic Publication: 2025 Aug 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: NAV1.7 Voltage-Gated Sodium Channel*/metabolism , Sulfonamides*/pharmacology , Sulfonamides*/chemical synthesis , Sulfonamides*/chemistry , Analgesics*/pharmacology , Analgesics*/chemical synthesis , Analgesics*/chemistry , Drug Design* , Voltage-Gated Sodium Channel Blockers*/pharmacology , Voltage-Gated Sodium Channel Blockers*/chemical synthesis , Voltage-Gated Sodium Channel Blockers*/chemistry, Structure-Activity Relationship ; Animals ; Humans ; Molecular Structure ; Molecular Docking Simulation ; Rats ; Dose-Response Relationship, Drug ; Male ; Mice ; Rats, Sprague-Dawley ; Neuralgia/drug therapy

Fixed-duration ibrutinib-venetoclax with MRD-guided ibrutinib-obinutuzumab intensification in first-line chronic lymphocytic leukaemia (HOVON 158/NEXT STEP): primary analysis of a multicentre, open-label, phase 2 trial.

Autoren: Kater AP Kersting S Dubois JM et al.

Quelle: The Lancet. Haematology [Lancet Haematol] 2025 Dec; Vol. 12 (12), pp. e935-e945.

Publikationsart: Journal Article; Clinical Trial, Phase II; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101643584 Publication Model: Print Cited Medium: Internet ISSN: 2352-3026 (Electronic) Linking ISSN: 23523026 NLM ISO Abbreviation: Lancet Haematol Subsets: MEDLINE

MeSH-Schlagworte: Leukemia, Lymphocytic, Chronic, B-Cell*/drug therapy , Leukemia, Lymphocytic, Chronic, B-Cell*/pathology , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/adverse effects , Sulfonamides*/administration & dosage , Sulfonamides*/therapeutic use , Sulfonamides*/adverse effects , Bridged Bicyclo Compounds, Heterocyclic*/administration & dosage , Bridged Bicyclo Compounds, Heterocyclic*/therapeutic use , Bridged Bicyclo Compounds, Heterocyclic*/adverse effects , Antibodies, Monoclonal, Humanized*/administration & dosage , Antibodies, Monoclonal, Humanized*/therapeutic use , Antibodies, Monoclonal, Humanized*/adverse effects, Humans ; Male ; Female ; Aged ; Middle Aged ; Adenine/analogs & derivatives ; Neoplasm, Residual ; Piperidines ; Aged, 80 and over ; Adult

Venetoclax plus azacitidine in relapsed or refractory T-cell acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 trial.

Autoren: Cao HY Zhang H Zhang Y et al.

Quelle: The Lancet. Haematology [Lancet Haematol] 2025 Dec; Vol. 12 (12), pp. e946-e955.

Publikationsart: Journal Article; Clinical Trial, Phase II; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101643584 Publication Model: Print Cited Medium: Internet ISSN: 2352-3026 (Electronic) Linking ISSN: 23523026 NLM ISO Abbreviation: Lancet Haematol Subsets: MEDLINE

MeSH-Schlagworte: Azacitidine*/therapeutic use , Azacitidine*/administration & dosage , Azacitidine*/adverse effects , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/adverse effects , Sulfonamides*/therapeutic use , Sulfonamides*/administration & dosage , Sulfonamides*/adverse effects , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/pathology , Bridged Bicyclo Compounds, Heterocyclic*/therapeutic use , Bridged Bicyclo Compounds, Heterocyclic*/administration & dosage , Bridged Bicyclo Compounds, Heterocyclic*/adverse effects, Humans ; Adult ; Middle Aged ; Male ; Female ; Aged ; Adolescent ; Young Adult ; Recurrence ; Treatment Outcome

Sulphonamide derivatives with a triazine core as novel inducers of apoptosis and pyroptosis in glioblastoma multiforme cells.

Autoren: Szewczyk-Roszczenko OK Kotwica-Mojzych K Roszczenko P et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2594158. Date of Electronic Publication: 2025 Dec 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Glioblastoma*/pathology , Glioblastoma*/drug therapy , Glioblastoma*/metabolism , Pyroptosis*/drug effects , Apoptosis*/drug effects , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Sulfonamides*/pharmacology , Sulfonamides*/chemistry , Sulfonamides*/chemical synthesis , Triazines*/chemistry , Triazines*/pharmacology , Triazines*/chemical synthesis, Humans ; Zebrafish ; Animals ; Drug Screening Assays, Antitumor ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cell Line, Tumor ; Reactive Oxygen Species/metabolism ; Tumor Cells, Cultured ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/pathology ; Neoplasms, Experimental/metabolism

Maintained improvement of outcomes related to skin clearance, itch, sleep and quality of life with baricitinib in adults with moderate-to-severe Atopic Dermatitis who were treated for up to 200 weeks in a randomized trial.

Autoren: Wollenberg A Costanzo A Vestergaard C et al.

Quelle: The Journal of dermatological treatment [J Dermatolog Treat] 2025 Dec; Vol. 36 (1), pp. 2585244. Date of Electronic Publication: 2025 Nov 27.

Publikationsart: Journal Article; Randomized Controlled Trial; Multicenter Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE

MeSH-Schlagworte: Dermatitis, Atopic*/drug therapy , Dermatitis, Atopic*/diagnosis , Dermatitis, Atopic*/complications , Azetidines*/administration & dosage , Azetidines*/therapeutic use , Azetidines*/adverse effects , Sulfonamides*/administration & dosage , Sulfonamides*/therapeutic use , Quality of Life* , Pruritus*/drug therapy , Pruritus*/etiology , Dermatologic Agents*/administration & dosage, Humans ; Purines ; Adult ; Female ; Male ; Severity of Illness Index ; Treatment Outcome ; Middle Aged ; Pyrazoles ; Double-Blind Method ; Young Adult

Effectiveness and safety of Baricitinib in alopecia areata: a prospective cohort study.

Autoren: Muñoz-Barba D García-Moronta C Haselgruber-de Francisco S et al.

Quelle: The Journal of dermatological treatment [J Dermatolog Treat] 2025 Dec; Vol. 36 (1), pp. 2583877. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE

MeSH-Schlagworte: Alopecia Areata*/drug therapy , Alopecia Areata*/diagnosis , Azetidines*/adverse effects , Azetidines*/therapeutic use , Azetidines*/administration & dosage , Sulfonamides*/adverse effects , Sulfonamides*/therapeutic use , Sulfonamides*/administration & dosage , Pyrazoles*/adverse effects , Pyrazoles*/therapeutic use, Humans ; Purines/adverse effects ; Female ; Male ; Prospective Studies ; Adult ; Middle Aged ; Treatment Outcome ; Severity of Illness Index ; Young Adult ; Follow-Up Studies

From Sulfa Drugs to New Antibacterial Agents: Advances in Chemical Modification of Approved Sulfonamides.

Autoren: Karagüzel A Koçak Aslan E Gündüz MG

Quelle: Drug development research [Drug Dev Res] 2025 Dec; Vol. 86 (8), pp. e70191.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/pharmacology , Sulfonamides*/chemistry , Sulfonamides*/pharmacology, Humans ; Animals ; Bacterial Infections/drug therapy ; Drug Resistance, Bacterial/drug effects ; Drug Design ; Dihydropteroate Synthase/antagonists & inhibitors

Novel 2-oxoethylthio-sulfonamide derivatives targeting pyocyanin/staphyloxanthin producing-pathogens: Antibiofilm, DHPS inhibition and gamma radiation effects.

Autoren: Ghorab MM Aboul-Magd DS Soliman AM

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109228. Date of Electronic Publication: 2025 Nov 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/chemical synthesis , Biofilms*/drug effects , Sulfonamides*/pharmacology , Sulfonamides*/chemistry , Sulfonamides*/chemical synthesis , Pseudomonas aeruginosa*/drug effects , Pyocyanine*/antagonists & inhibitors , Pyocyanine*/biosynthesis , Pyocyanine*/metabolism , Staphylococcus aureus*/drug effects, Microbial Sensitivity Tests ; Structure-Activity Relationship ; Molecular Structure ; Gamma Rays ; Dose-Response Relationship, Drug ; Molecular Docking Simulation ; Xanthophylls

Design, development, and in vivo characterization of ocular pH-based in situ thixotropic gelling system for the therapy of Glaucoma.

Autoren: Arora A Kaul S Atre B et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 334 (Pt 1), pp. 149008. Date of Electronic Publication: 2025 Nov 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Glaucoma*/drug therapy , Sulfonamides*/chemistry , Sulfonamides*/pharmacology , Sulfonamides*/administration & dosage, Animals ; Hydrogen-Ion Concentration ; Gels/chemistry ; Mice ; Intraocular Pressure/drug effects ; Drug Liberation ; Mice, Inbred BALB C ; Chitosan/chemistry ; Aqueous Humor ; Isoquinolines

The efficacy of varying doses of venetoclax combined with azacitidine for newly diagnosed adult acute myeloid leukemia in real-world settings: a single-center retrospective analysis.

Autoren: Mao Y Cai Y Wu Y et al.

Quelle: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2571248. Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH-Schlagworte: Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/mortality , Leukemia, Myeloid, Acute*/diagnosis , Azacitidine*/administration & dosage , Azacitidine*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/adverse effects , Sulfonamides*/administration & dosage , Sulfonamides*/therapeutic use, Humans ; Female ; Male ; Retrospective Studies ; Middle Aged ; Adult ; Aged ; Bridged Bicyclo Compounds, Heterocyclic/administration & dosage ; Bridged Bicyclo Compounds, Heterocyclic/therapeutic use ; Treatment Outcome ; Aged, 80 and over