Výsledky vyhledávání - "Subthalamic nucleus"

Precise Electrode Co-Alignment in Deep Brain Stimulation Fusing Neuroimaging and Electrophysiology.

Autoři: Varga I Novak D Urgosik D a další

Zdroj: The European journal of neuroscience [Eur J Neurosci] 2025 Nov; Vol. 62 (10), pp. e70309.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley-Blackwell Country of Publication: France NLM ID: 8918110 Publication Model: Print Cited Medium: Internet ISSN: 1460-9568 (Electronic) Linking ISSN: 0953816X NLM ISO Abbreviation: Eur J Neurosci Subsets: MEDLINE

Výrazy ze slovníku MeSH: Deep Brain Stimulation*/methods , Deep Brain Stimulation*/instrumentation , Subthalamic Nucleus*/diagnostic imaging , Subthalamic Nucleus*/surgery , Neuroimaging*/methods , Parkinson Disease*/therapy , Parkinson Disease*/diagnostic imaging , Parkinson Disease*/surgery, Humans ; Magnetic Resonance Imaging/methods ; Electrodes, Implanted ; Microelectrodes ; Neural Networks, Computer ; Retrospective Studies ; Male ; Female ; Middle Aged

The Impact of Deep Brain Stimulation of the Subthalamic Nucleus on Sleep-Wake Function and Circadian Rhythms in Patients with Parkinson's Disease.

Autoři: Steinhardt J Lokowandt L Schmidt CX a další

Zdroj: Movement disorders clinical practice [Mov Disord Clin Pract] 2025 Nov; Vol. 12 (11), pp. 1801-1810. Date of Electronic Publication: 2025 Jun 04.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 101630279 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2330-1619 (Electronic) Linking ISSN: 23301619 NLM ISO Abbreviation: Mov Disord Clin Pract Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/therapy , Parkinson Disease*/complications , Parkinson Disease*/physiopathology , Deep Brain Stimulation*/methods , Subthalamic Nucleus*/physiology , Subthalamic Nucleus*/physiopathology , Circadian Rhythm*/physiology , Sleep Wake Disorders*/etiology , Sleep Wake Disorders*/therapy , Sleep*/physiology, Humans ; Male ; Female ; Middle Aged ; Aged ; Actigraphy

Dysfunction of subthalamic dopaminergic circuitry contributes to anxiety- and depression-like behaviors in 6-OHDA lesion-induced hemiparkinsonian mice.

Autoři: Zhang JQ Li SY Yin C a další

Zdroj: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2025 Oct; Vol. 46 (10), pp. 2622-2636. Date of Electronic Publication: 2025 May 06.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

Výrazy ze slovníku MeSH: Anxiety*/metabolism , Anxiety*/physiopathology , Depression*/metabolism , Depression*/physiopathology , Subthalamic Nucleus*/metabolism , Subthalamic Nucleus*/physiopathology , Subthalamic Nucleus*/drug effects , Dopamine*/metabolism , Parkinsonian Disorders*/chemically induced, Animals ; Oxidopamine ; Male ; Mice ; Behavior, Animal/drug effects ; Mice, Inbred C57BL ; Disease Models, Animal ; Apomorphine/pharmacology ; Desipramine/pharmacology ; Parkinson Disease ; Motor Activity/drug effects

Molecular glucose imaging reveals functional brain reconfiguration by subthalamic deep brain stimulation in Parkinsonian rats.

Autoři: Chen J Li N Muthuraman M a další

Zdroj: Translational neurodegeneration [Transl Neurodegener] 2025 Dec 02; Vol. 14 (1), pp. 62. Date of Electronic Publication: 2025 Dec 02.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158 (Print) Linking ISSN: 20479158 NLM ISO Abbreviation: Transl Neurodegener Subsets: MEDLINE

Výrazy ze slovníku MeSH: Deep Brain Stimulation*/methods , Subthalamic Nucleus*/metabolism , Subthalamic Nucleus*/diagnostic imaging , Brain*/metabolism , Brain*/diagnostic imaging , Glucose*/metabolism , Parkinson Disease*/metabolism , Parkinson Disease*/therapy , Parkinson Disease*/diagnostic imaging , Molecular Imaging*/methods, Animals ; Rats ; Positron-Emission Tomography/methods ; Male ; Fluorodeoxyglucose F18 ; Rats, Transgenic ; Disease Models, Animal ; Rats, Sprague-Dawley ; Humans

An exploratory study on surgical planning of single trajectory deep brain stimulation of ventral intermediate nucleus and subthalamic nucleus.

Autoři: Sakakura K Pu Q Pertsch N a další

Zdroj: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2025 Dec; Vol. 259, pp. 109213. Date of Electronic Publication: 2025 Oct 26.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7502039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6968 (Electronic) Linking ISSN: 03038467 NLM ISO Abbreviation: Clin Neurol Neurosurg Subsets: MEDLINE

Výrazy ze slovníku MeSH: Deep Brain Stimulation*/methods , Subthalamic Nucleus*/surgery , Parkinson Disease*/therapy , Parkinson Disease*/surgery , Neurosurgical Procedures*/methods , Ventral Thalamic Nuclei*/surgery, Humans ; Male ; Female ; Middle Aged ; Aged ; Tremor/therapy ; Tremor/surgery

Unipolar recordings of beta power inform initial programming of the subthalamic nucleus in Parkinson's disease.

Autoři: Thompson JA Radcliffe EM Ojemann S a další

Zdroj: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2025 Dec; Vol. 141, pp. 108078. Date of Electronic Publication: 2025 Oct 10.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5126 (Electronic) Linking ISSN: 13538020 NLM ISO Abbreviation: Parkinsonism Relat Disord Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/therapy , Parkinson Disease*/physiopathology , Subthalamic Nucleus*/physiology , Subthalamic Nucleus*/physiopathology , Deep Brain Stimulation*/methods , Beta Rhythm*/physiology, Humans ; Male ; Female ; Middle Aged ; Aged ; Adult

Low β predicts motor output and cell degeneration in the A53T Parkinson's disease rat model.

Autoři: Hofman K Chen J Sil T a další

Zdroj: Brain : a journal of neurology [Brain] 2025 Nov 04; Vol. 148 (11), pp. 4058-4071.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/physiopathology , Parkinson Disease*/pathology , Parkinson Disease*/genetics , Subthalamic Nucleus*/physiopathology , Subthalamic Nucleus*/pathology , Beta Rhythm*/physiology , Nerve Degeneration*/physiopathology , Nerve Degeneration*/pathology, Animals ; Rats ; Disease Models, Animal ; Male ; alpha-Synuclein/genetics ; alpha-Synuclein/metabolism ; Rats, Transgenic ; Motor Cortex/physiopathology ; Motor Cortex/pathology ; Disease Progression

Clinical predictors of speech changes after subthalamic neurostimulation in Parkinson's disease.

Autoři: Cavallieri F Bove F Zampogna A a další

Zdroj: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2025 Nov; Vol. 46 (11), pp. 5837-5846. Date of Electronic Publication: 2025 Aug 25.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100959175 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3478 (Electronic) Linking ISSN: 15901874 NLM ISO Abbreviation: Neurol Sci Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/therapy , Parkinson Disease*/complications , Parkinson Disease*/physiopathology , Deep Brain Stimulation*/adverse effects , Deep Brain Stimulation*/methods , Subthalamic Nucleus*/physiopathology , Speech Disorders*/etiology , Speech Disorders*/diagnosis , Speech Disorders*/therapy , Speech*/physiology, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Treatment Outcome ; Follow-Up Studies

Peripheral cytokine levels in patients with idiopathic parkinson's disease undergoing subthalamic nucleus deep brain stimulation.

Autoři: Kocabıcak E Sen S Uzun H a další

Zdroj: Scientific reports [Sci Rep] 2025 Oct 21; Vol. 15 (1), pp. 36719. Date of Electronic Publication: 2025 Oct 21.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/therapy , Parkinson Disease*/blood , Deep Brain Stimulation*/methods , Subthalamic Nucleus*/physiopathology , Cytokines*/blood, Humans ; Male ; Female ; Middle Aged ; Aged ; Biomarkers/blood ; Treatment Outcome

The microlesion effect is associated with global cognitive impairment and predicts motor outcomes after subthalamic deep brain stimulation in Parkinson's disease.

Autoři: Liang L Zhao J Wang H a další

Zdroj: Journal of neurology [J Neurol] 2025 Oct 18; Vol. 272 (11), pp. 708. Date of Electronic Publication: 2025 Oct 18.

Způsob vydávání: Journal Article; Observational Study

Informace o časopise: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/physiopathology , Deep Brain Stimulation*/adverse effects , Deep Brain Stimulation*/methods , Parkinson Disease*/therapy , Parkinson Disease*/complications , Parkinson Disease*/physiopathology , Subthalamic Nucleus*/surgery, Aged ; Female ; Humans ; Male ; Middle Aged ; Follow-Up Studies ; Prospective Studies ; Treatment Outcome

Acute Cortical Stroke Alters Neural Activity in Subthalamic Nucleus, Which Correlates With Motor Disability in Rats.

Autoři: Deng Z Mc Laughlin M Kilic U a další

Zdroj: Stroke [Stroke] 2025 Oct; Vol. 56 (10), pp. 3060-3071. Date of Electronic Publication: 2025 Aug 12.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE

Výrazy ze slovníku MeSH: Stroke*/physiopathology , Motor Cortex*/pathology , Subthalamic Nucleus*/physiopathology , Motor Disorders*/etiology, Animals ; Rats ; Rats, Sprague-Dawley ; Male

Deep brain stimulation of the subthalamic nucleus in Parkinson disease 2013-2023: where are we a further 10 years on?

Autoři: O'Keeffe AB Merla A Ashkan K

Zdroj: British journal of neurosurgery [Br J Neurosurg] 2025 Oct; Vol. 39 (5), pp. 603-611. Date of Electronic Publication: 2024 Feb 07.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8800054 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1360-046X (Electronic) Linking ISSN: 02688697 NLM ISO Abbreviation: Br J Neurosurg Subsets: MEDLINE

Výrazy ze slovníku MeSH: Deep Brain Stimulation*/methods , Deep Brain Stimulation*/trends , Parkinson Disease*/therapy , Subthalamic Nucleus*/surgery, Humans

Relationships between neuronal loss, age of death, disease duration and MRI brain volumes in progressive supranuclear palsy.

Autoři: Kumar M Roemer SF Tosakulwong N a další

Zdroj: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2025 Oct; Vol. 139, pp. 107980. Date of Electronic Publication: 2025 Jul 30.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5126 (Electronic) Linking ISSN: 13538020 NLM ISO Abbreviation: Parkinsonism Relat Disord Subsets: MEDLINE

Výrazy ze slovníku MeSH: Supranuclear Palsy, Progressive*/pathology , Supranuclear Palsy, Progressive*/diagnostic imaging , Neurons*/pathology , Red Nucleus*/pathology , Red Nucleus*/diagnostic imaging , Subthalamic Nucleus*/pathology , Subthalamic Nucleus*/diagnostic imaging , Brain*/pathology, Humans ; Female ; Male ; Aged ; Magnetic Resonance Imaging ; Aged, 80 and over ; Middle Aged ; Disease Progression ; tau Proteins/metabolism ; Prospective Studies

Differential synaptic depression mediates the therapeutic effect of deep brain stimulation.

Autoři: Li J Zhou J He B a další

Zdroj: Nature neuroscience [Nat Neurosci] 2025 Dec; Vol. 28 (12), pp. 2575-2587. Date of Electronic Publication: 2025 Oct 16.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

Výrazy ze slovníku MeSH: Deep Brain Stimulation*/methods , Subthalamic Nucleus*/physiology , Synapses*/physiology, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Glutamic Acid/metabolism ; Disease Models, Animal ; Oxidopamine/toxicity ; Neurons/physiology ; Neurons/drug effects ; gamma-Aminobutyric Acid/metabolism

"YiJinJing, Wohu Pushi" Posture-Voice Therapy for Dysarthria in Parkinson's Disease Patients Following Subthalamic Nucleus Deep Brain Stimulation: A Randomized Controlled Trial.

Autoři: Yang M Sun X Yan J a další

Zdroj: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2025 Nov; Vol. 31 (11), pp. e70652.

Způsob vydávání: Journal Article; Randomized Controlled Trial

Informace o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/therapy , Parkinson Disease*/complications , Deep Brain Stimulation*/adverse effects , Deep Brain Stimulation*/methods , Dysarthria*/therapy , Dysarthria*/etiology , Subthalamic Nucleus*/physiology , Posture*/physiology, Humans ; Male ; Female ; Middle Aged ; Aged ; Treatment Outcome ; Prospective Studies ; Follow-Up Studies

Five-Year Outcomes from Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson Disease.

Autoři: Starr PA Shivacharan RS Goldberg E a další

Korporace: Starr PA Shivacharan RS Goldberg E a další

Zdroj: JAMA neurology [JAMA Neurol] 2025 Nov 01; Vol. 82 (11), pp. 1181-1190.

Způsob vydávání: Journal Article; Randomized Controlled Trial; Multicenter Study

Informace o časopise: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/therapy , Parkinson Disease*/physiopathology , Deep Brain Stimulation*/methods , Deep Brain Stimulation*/trends , Deep Brain Stimulation*/adverse effects , Subthalamic Nucleus*/physiology, Humans ; Male ; Female ; Middle Aged ; Double-Blind Method ; Aged ; Treatment Outcome ; Prospective Studies ; Follow-Up Studies

DBS-STN&SNr combined stimulation versus DBS-STN monotarget stimulation for Parkinson's disease freezing: A comparative efficacy study.

Autoři: Tan B Chen T Guo P a další

Zdroj: Journal of Parkinson's disease [J Parkinsons Dis] 2025 Nov; Vol. 15 (7), pp. 1264-1274. Date of Electronic Publication: 2025 Aug 04.

Způsob vydávání: Journal Article; Randomized Controlled Trial; Multicenter Study; Comparative Study

Informace o časopise: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101567362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-718X (Electronic) Linking ISSN: 18777171 NLM ISO Abbreviation: J Parkinsons Dis Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/therapy , Parkinson Disease*/complications , Parkinson Disease*/physiopathology , Deep Brain Stimulation*/methods , Subthalamic Nucleus* , Gait Disorders, Neurologic*/therapy , Gait Disorders, Neurologic*/etiology , Substantia Nigra* , Outcome Assessment, Health Care*, Humans ; Male ; Female ; Middle Aged ; Cross-Over Studies ; Aged ; Prospective Studies ; Quality of Life

Differential Effects of Levodopa and Stimulation on Post-Surgery Freezing of Gait in Subthalamic Nucleus Deep Brain Stimulation Parkinson's Disease Patients: A Clinical and Kinematic Analysis.

Autoři: Barbosa R Bastos P Pita Lobo P a další

Zdroj: Movement disorders clinical practice [Mov Disord Clin Pract] 2025 Nov; Vol. 12 (11), pp. 1859-1872. Date of Electronic Publication: 2025 Jun 12.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 101630279 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2330-1619 (Electronic) Linking ISSN: 23301619 NLM ISO Abbreviation: Mov Disord Clin Pract Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/therapy , Parkinson Disease*/complications , Deep Brain Stimulation*/methods , Levodopa*/therapeutic use , Levodopa*/pharmacology , Subthalamic Nucleus*/physiology , Gait Disorders, Neurologic*/etiology , Gait Disorders, Neurologic*/therapy , Gait Disorders, Neurologic*/drug therapy , Antiparkinson Agents*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Aged ; Biomechanical Phenomena ; Treatment Outcome

Subthalamic Electrophysiological Mapping of Gait Initiation Dynamics and Freezing in Parkinson's Disease.

Autoři: Collomb-Clerc A Yeche M Demain A a další

Zdroj: Annals of neurology [Ann Neurol] 2025 Nov; Vol. 98 (5), pp. 977-990. Date of Electronic Publication: 2025 Jul 25.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/physiopathology , Parkinson Disease*/complications , Parkinson Disease*/therapy , Parkinson Disease*/drug therapy , Subthalamic Nucleus*/physiopathology , Gait Disorders, Neurologic*/physiopathology , Gait Disorders, Neurologic*/etiology, Humans ; Male ; Female ; Middle Aged ; Aged ; Deep Brain Stimulation ; Brain Mapping

The effect of subthalamic nucleus deep brain stimulation on speech metrics in Parkinson's disease.

Autoři: Je G Akella P Wilkins KB a další

Zdroj: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2025 Nov; Vol. 140, pp. 108053. Date of Electronic Publication: 2025 Sep 17.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5126 (Electronic) Linking ISSN: 13538020 NLM ISO Abbreviation: Parkinsonism Relat Disord Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parkinson Disease*/complications , Parkinson Disease*/therapy , Parkinson Disease*/physiopathology , Deep Brain Stimulation*/methods , Subthalamic Nucleus* , Speech Disorders*/etiology , Speech Disorders*/therapy , Speech*/physiology , Outcome Assessment, Health Care*, Humans ; Male ; Female ; Middle Aged ; Aged