Výsledky vyhledávání - "Subcutaneous Fat"

Reduction of Subcutaneous and Visceral Fat With the Use of Energy-Based Equipment With a High-Power Amplifying Effect Plus an Exercise Regimen.

Autoři: Rodriguez Lastra J Kouser S

Zdroj: Journal of cosmetic dermatology [J Cosmet Dermatol] 2025 Oct; Vol. 24 (10), pp. e70490.

Způsob vydávání: Clinical Trial; Journal Article

Informace o časopise: Publisher: Blackwell Science Country of Publication: England NLM ID: 101130964 Publication Model: Print Cited Medium: Internet ISSN: 1473-2165 (Electronic) Linking ISSN: 14732130 NLM ISO Abbreviation: J Cosmet Dermatol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Exercise* , Exercise Therapy*/methods , Intra-Abdominal Fat*/diagnostic imaging , Intra-Abdominal Fat*/radiation effects , Radiofrequency Therapy*/instrumentation , Subcutaneous Fat*/diagnostic imaging , Subcutaneous Fat*/radiation effects , Subcutaneous Fat, Abdominal*/diagnostic imaging , Subcutaneous Fat, Abdominal*/radiation effects, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Combined Modality Therapy ; Leptin/blood ; Magnetic Resonance Imaging ; Pilot Projects ; Treatment Outcome

Correlation analysis of key genes and immune infiltration in visceral adipose tissue and subcutaneous adipose tissue of patients with type 2 diabetes in women.

Autoři: Shi Q Li Y Liu C a další

Zdroj: Adipocyte [Adipocyte] 2025 Dec; Vol. 14 (1), pp. 2442419. Date of Electronic Publication: 2024 Dec 24.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101567863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-397X (Electronic) Linking ISSN: 21623945 NLM ISO Abbreviation: Adipocyte Subsets: MEDLINE

Výrazy ze slovníku MeSH: Diabetes Mellitus, Type 2*/genetics , Diabetes Mellitus, Type 2*/immunology , Diabetes Mellitus, Type 2*/metabolism , Intra-Abdominal Fat*/metabolism , Intra-Abdominal Fat*/immunology , Subcutaneous Fat*/metabolism , Subcutaneous Fat*/immunology, Humans ; Female ; Transcriptome ; Gene Expression Profiling ; Macrophages/immunology ; Macrophages/metabolism ; Protein Interaction Maps

Human deep subcutaneous adipose tissue is enriched for inflammatory and tissue remodeling pathways.

Autoři: Yamada K Kubota Y Kosaka K a další

Zdroj: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2025 Oct 01; Vol. 329 (4), pp. C1161-C1172. Date of Electronic Publication: 2025 Aug 20.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Subcutaneous Fat*/metabolism , Subcutaneous Fat*/pathology , Inflammation*/genetics , Inflammation*/metabolism , Inflammation*/pathology, Humans ; Macrophages/metabolism ; Oxidative Stress/genetics ; Transcriptome ; Male ; Signal Transduction ; Female ; Fibroblasts/metabolism ; Single-Cell Analysis ; Middle Aged ; Lipid Metabolism ; Adult ; Adipocytes/metabolism

Genetic Determinants of Fatty Acid Composition in Subcutaneous and Visceral Adipose Tissue.

Autoři: Ahmed A Naz A Thanaj M a další

Zdroj: Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2025 Dec; Vol. 33 (12), pp. 2406-2415. Date of Electronic Publication: 2025 Sep 29.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101264860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1930-739X (Electronic) Linking ISSN: 19307381 NLM ISO Abbreviation: Obesity (Silver Spring) Subsets: MEDLINE

Výrazy ze slovníku MeSH: Intra-Abdominal Fat*/metabolism , Fatty Acids*/metabolism , Subcutaneous Fat*/metabolism , Subcutaneous Fat*/chemistry, Humans ; Male ; Female ; Genome-Wide Association Study ; Middle Aged ; Polymorphism, Single Nucleotide ; Aged ; Quantitative Trait Loci ; Magnetic Resonance Imaging ; Diabetes Mellitus, Type 2/genetics ; Kruppel-Like Transcription Factors/genetics ; Adult

Distinct metabolic associations of subcutaneous and visceral adipocyte morphology in women with or without obesity.

Autoři: Maikaew P Phattanakiatsakul T Sitticharoon C a další

Zdroj: Scientific reports [Sci Rep] 2025 Nov 21; Vol. 15 (1), pp. 41287. Date of Electronic Publication: 2025 Nov 21.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy ze slovníku MeSH: Obesity*/metabolism , Obesity*/pathology , Obesity*/blood , Adipocytes*/metabolism , Adipocytes*/pathology , Intra-Abdominal Fat*/metabolism , Intra-Abdominal Fat*/pathology , Subcutaneous Fat*/metabolism , Subcutaneous Fat*/pathology, Humans ; Female ; Middle Aged ; Adult ; Insulin Resistance ; Cross-Sectional Studies ; Adiponectin/blood ; Leptin/blood ; Cytokines/blood ; Cytokines/genetics ; Cytokines/metabolism ; Nicotinamide Phosphoribosyltransferase/genetics ; Nicotinamide Phosphoribosyltransferase/blood ; Nicotinamide Phosphoribosyltransferase/metabolism ; GPI-Linked Proteins/blood ; GPI-Linked Proteins/metabolism ; GPI-Linked Proteins/genetics ; Lectins/blood ; Lectins/genetics ; Lectins/metabolism

An ovine model shows that subcutaneous adipose tissue fibrosis occurs early in polycystic ovary syndrome (PCOS).

Autoři: Wang Y Levate G Rae MT a další

Zdroj: Journal of molecular endocrinology [J Mol Endocrinol] 2025 Nov 19; Vol. 75 (4). Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioScientifica Country of Publication: England NLM ID: 8902617 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1479-6813 (Electronic) Linking ISSN: 09525041 NLM ISO Abbreviation: J Mol Endocrinol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Polycystic Ovary Syndrome*/pathology , Polycystic Ovary Syndrome*/metabolism , Polycystic Ovary Syndrome*/genetics , Subcutaneous Fat*/pathology , Subcutaneous Fat*/metabolism, Animals ; Female ; Sheep ; Disease Models, Animal ; Fibrosis ; Adipogenesis ; Pregnancy ; Adipocytes/metabolism ; Adipocytes/pathology

Subcutaneous white adipose tissue-derived extracellular vesicles maintain intestinal homeostasis via IgA biosynthesis in aging mice.

Autoři: Long K Liu P Wang Y a další

Zdroj: The Journal of clinical investigation [J Clin Invest] 2025 Nov 17; Vol. 135 (22). Date of Electronic Publication: 2025 Nov 17 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Výrazy ze slovníku MeSH: Extracellular Vesicles*/immunology , Extracellular Vesicles*/metabolism , Immunoglobulin A*/biosynthesis , Immunoglobulin A*/immunology , Aging*/immunology , Aging*/pathology , Adipose Tissue, White*/immunology , Adipose Tissue, White*/metabolism , Adipose Tissue, White*/pathology , Homeostasis* , Gastrointestinal Microbiome*/immunology , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/immunology , Subcutaneous Fat*/immunology , Subcutaneous Fat*/metabolism , Intestine, Small*/immunology , Intestine, Small*/metabolism, Animals ; Mice ; Male ; Tretinoin/metabolism ; Mice, Inbred C57BL

Molecular responses in abdominal subcutaneous adipose tissue after a session of endurance exercise: effects of exercise intensity.

Autoři: Ahn C Zhang T Rode T a další

Zdroj: The Journal of physiology [J Physiol] 2025 Nov; Vol. 603 (22), pp. 6895-6919. Date of Electronic Publication: 2025 Oct 12.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Subcutaneous Fat, Abdominal*/metabolism , Subcutaneous Fat, Abdominal*/physiology , Exercise*/physiology , Physical Endurance*, Humans ; Male ; Adult ; Female ; Transcriptome ; Young Adult

Genotype and dietary inclusion of omega-3 fatty acids and fiber influence metabolism of subcutaneous adipose tissue and systemic metabolic outcomes in growing pigs.

Autoři: Gondret F Sierżant K Lebret B

Zdroj: Meat science [Meat Sci] 2025 Nov; Vol. 229, pp. 109911. Date of Electronic Publication: 2025 Jul 12.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 101160862 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4138 (Electronic) Linking ISSN: 03091740 NLM ISO Abbreviation: Meat Sci Subsets: MEDLINE

Výrazy ze slovníku MeSH: Subcutaneous Fat*/metabolism , Fatty Acids, Omega-3*/administration & dosage , Diet*/veterinary , Sus scrofa*/genetics , Sus scrofa*/metabolism , Sus scrofa*/growth & development , Dietary Fiber*/administration & dosage, Animals ; Female ; Animal Feed/analysis ; Genotype ; Antioxidants/analysis

CCL26 and CXCL12 preserve insulin-sensitizing macrophages in subcutaneous adipose tissue in obesity.

Autoři: Jeelani I Franco da Cunha F Rohm TV a další

Zdroj: Cell reports [Cell Rep] 2025 Oct 28; Vol. 44 (10), pp. 116450. Date of Electronic Publication: 2025 Oct 15.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Výrazy ze slovníku MeSH: Chemokine CXCL12*/metabolism , Obesity*/metabolism , Obesity*/pathology , Macrophages*/metabolism , Subcutaneous Fat*/metabolism , Subcutaneous Fat*/pathology , Insulin*/metabolism, Animals ; Mice ; Insulin Resistance ; Mice, Inbred C57BL ; Male ; Extracellular Vesicles/metabolism ; Adipocytes/metabolism ; Humans

Sex-Specific Differences in Visceral and Subcutaneous Adiposity Accumulation and Their Association With Metabolic Abnormalities.

Autoři: Rodrigues IG Arcoverde GMPF do Nascimento CLC a další

Zdroj: Journal of obesity [J Obes] 2025 Oct 27; Vol. 2025, pp. 7240063. Date of Electronic Publication: 2025 Oct 27 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 101526295 Publication Model: eCollection Cited Medium: Internet ISSN: 2090-0716 (Electronic) Linking ISSN: 20900708 NLM ISO Abbreviation: J Obes Subsets: MEDLINE

Výrazy ze slovníku MeSH: Intra-Abdominal Fat*/diagnostic imaging , Intra-Abdominal Fat*/metabolism , Subcutaneous Fat*/diagnostic imaging , Subcutaneous Fat*/metabolism , Adiposity*, Humans ; Male ; Female ; Middle Aged ; Cross-Sectional Studies ; Adult ; Sex Factors

The influence of muscle size and density, as well as subcutaneous adipose tissue, on mortality risk in elderly women across different age groups.

Autoři: Li Y Hu Y Jiang R a další

Zdroj: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2025 Oct 22; Vol. 26 (1), pp. 984. Date of Electronic Publication: 2025 Oct 22.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474 (Electronic) Linking ISSN: 14712474 NLM ISO Abbreviation: BMC Musculoskelet Disord Subsets: MEDLINE

Výrazy ze slovníku MeSH: Subcutaneous Fat*/diagnostic imaging , Subcutaneous Fat*/pathology , Muscle, Skeletal*/diagnostic imaging , Muscle, Skeletal*/pathology , Muscle, Skeletal*/anatomy & histology , Hip Fractures*/mortality , Hip Fractures*/diagnostic imaging, Humans ; Female ; Aged ; Aged, 80 and over ; Retrospective Studies ; Age Factors ; Buttocks/diagnostic imaging ; Risk Factors ; Tomography, X-Ray Computed ; Follow-Up Studies ; Organ Size

Comprehensive Identification of miRNAs and circRNAs in the Regulation of Intramuscular and Subcutaneous Fat Deposition in Meat Ducks.

Autoři: Wang Z Zhou T Liang W a další

Zdroj: Genes [Genes (Basel)] 2025 Oct 14; Vol. 16 (10). Date of Electronic Publication: 2025 Oct 14.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

Výrazy ze slovníku MeSH: MicroRNAs*/genetics , Ducks*/genetics , Ducks*/metabolism , Subcutaneous Fat*/metabolism , RNA, Circular*/genetics, Animals ; Adipocytes/metabolism ; Adipocytes/cytology ; Meat ; Cell Differentiation/genetics ; Transcriptome ; Muscle, Skeletal/metabolism ; Gene Regulatory Networks ; Gene Expression Profiling

Impact of Subcutaneous Adipose Tissue Index Change During Neoadjuvant Chemoradiotherapy on Disease-Free Survival and Tumor Response in Patients with Locally Advanced Rectal Cancer.

Autoři: Yang Q Lu S Qu R a další

Zdroj: International journal of medical sciences [Int J Med Sci] 2025 Oct 10; Vol. 22 (16), pp. 4313-4324. Date of Electronic Publication: 2025 Oct 10 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101213954 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-1907 (Electronic) Linking ISSN: 14491907 NLM ISO Abbreviation: Int J Med Sci Subsets: MEDLINE

Výrazy ze slovníku MeSH: Rectal Neoplasms*/therapy , Rectal Neoplasms*/mortality , Rectal Neoplasms*/pathology , Neoadjuvant Therapy*/methods , Subcutaneous Fat*/diagnostic imaging , Subcutaneous Fat*/pathology, Humans ; Male ; Female ; Middle Aged ; Aged ; Disease-Free Survival ; Prognosis ; Adult ; Retrospective Studies ; Tomography, X-Ray Computed ; Neoplasm Staging ; Chemoradiotherapy, Adjuvant/methods ; Treatment Outcome

Blood Pressure Mediates the Association Between Visceral-to-Subcutaneous Fat Ratio and Arterial Stiffness in Patients With Type 2 Diabetes.

Autoři: Tang D Gu X Xuan Y a další

Zdroj: Journal of diabetes research [J Diabetes Res] 2025 Oct 05; Vol. 2025, pp. 4898638. Date of Electronic Publication: 2025 Oct 05 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 101605237 Publication Model: eCollection Cited Medium: Internet ISSN: 2314-6753 (Electronic) NLM ISO Abbreviation: J Diabetes Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Vascular Stiffness*/physiology , Diabetes Mellitus, Type 2*/physiopathology , Diabetes Mellitus, Type 2*/complications , Intra-Abdominal Fat*/physiopathology , Blood Pressure*/physiology , Subcutaneous Fat*/physiopathology, Humans ; Male ; Female ; Middle Aged ; Cross-Sectional Studies ; Pulse Wave Analysis ; Aged ; Ankle Brachial Index ; Adult

Laparoscopic Appendectomy Is Superior in Patients with Higher Fat Thickness.

Autoři: Teke E Besler E Özdilek HB a další

Zdroj: JSLS : Journal of the Society of Laparoendoscopic Surgeons [JSLS] 2025 Oct-Dec; Vol. 29 (4). Date of Electronic Publication: 2025 Oct 31.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Society of Laparoscopic & Robotic Surgeons Country of Publication: United States NLM ID: 100884618 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-3797 (Electronic) Linking ISSN: 10868089 NLM ISO Abbreviation: JSLS Subsets: MEDLINE

Výrazy ze slovníku MeSH: Laparoscopy*/methods , Appendectomy*/methods , Appendicitis*/surgery , Appendicitis*/complications , Subcutaneous Fat*/diagnostic imaging, Humans ; Retrospective Studies ; Male ; Female ; Adult ; Middle Aged ; Tomography, X-Ray Computed ; Body Mass Index ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology ; Operative Time ; Postoperative Complications/epidemiology ; Treatment Outcome ; ROC Curve ; Length of Stay/statistics & numerical data

Keratinocyte-specific deletion of O-GlcNAc transferase reduces the subcutaneous adipocyte layer in mice.

Autoři: Kim KD Hong DG Jin S a další

Zdroj: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Oct 01; Vol. 783, pp. 152640. Date of Electronic Publication: 2025 Sep 12.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Výrazy ze slovníku MeSH: N-Acetylglucosaminyltransferases*/genetics , N-Acetylglucosaminyltransferases*/metabolism , N-Acetylglucosaminyltransferases*/deficiency , Keratinocytes*/metabolism , Keratinocytes*/enzymology , Keratinocytes*/cytology , Adipocytes*/metabolism , Adipocytes*/cytology , Subcutaneous Fat*/metabolism , Subcutaneous Fat*/cytology, Animals ; Mice, Knockout ; Mice ; Gene Deletion ; Skin/metabolism

Glucagon-like peptide-1 is involved in fasting and postprandial blood flow regulation of subcutaneous adipose tissue.

Autoři: Sotorník R Brassard P Ménard J a další

Zdroj: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Oct; Vol. 27 (10), pp. 5478-5486. Date of Electronic Publication: 2025 Jul 09.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Výrazy ze slovníku MeSH: Postprandial Period*/physiology , Glucagon-Like Peptide 1*/metabolism , Glucagon-Like Peptide 1*/physiology , Fasting*/physiology , Subcutaneous Fat*/blood supply , Subcutaneous Fat*/drug effects , Subcutaneous Fat*/metabolism, Humans ; Male ; Female ; Adult ; Regional Blood Flow/drug effects ; Regional Blood Flow/physiology ; Peptide Fragments/pharmacology ; Peptide Fragments/administration & dosage ; Blood Glucose/metabolism ; Young Adult ; Healthy Volunteers ; Glucagon-Like Peptide-1 Receptor/antagonists & inhibitors ; Middle Aged

Novel microRNA pathways of impaired angiogenesis in human peripheral artery disease adipose tissue.

Autoři: Okazaki RA Rizvi SH Bretón-Romero R a další

Zdroj: Vascular medicine (London, England) [Vasc Med] 2025 Oct; Vol. 30 (5), pp. 537-544. Date of Electronic Publication: 2025 Aug 25.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: SAGE Publications Country of Publication: England NLM ID: 9610930 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0377 (Electronic) Linking ISSN: 1358863X NLM ISO Abbreviation: Vasc Med Subsets: MEDLINE

Výrazy ze slovníku MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Peripheral Arterial Disease*/genetics , Peripheral Arterial Disease*/physiopathology , Peripheral Arterial Disease*/metabolism , Peripheral Arterial Disease*/surgery , Peripheral Arterial Disease*/pathology , Neovascularization, Physiologic*/genetics , Subcutaneous Fat*/blood supply , Subcutaneous Fat*/metabolism, Humans ; Male ; Female ; Aged ; Middle Aged ; Case-Control Studies ; Signal Transduction ; Neovascularization, Pathologic ; Gene Expression Profiling/methods ; Gene Expression Regulation ; Angiogenic Proteins/genetics ; Angiogenic Proteins/metabolism ; Adipose Tissue ; Angiogenesis

Prognosis of a deep excision margin within or beyond subcutaneous fat for invasive acral melanoma of the sole: A multi-institutional retrospective study.

Autoři: Koizumi S Yamazaki N Ichigozaki Y a další

Korporace: Koizumi S Yamazaki N Ichigozaki Y a další

Zdroj: Surgery [Surgery] 2025 Oct; Vol. 186, pp. 109573. Date of Electronic Publication: 2025 Jul 22.

Způsob vydávání: Journal Article; Multicenter Study

Informace o časopise: Publisher: Mosby Country of Publication: United States NLM ID: 0417347 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-7361 (Electronic) Linking ISSN: 00396060 NLM ISO Abbreviation: Surgery Subsets: MEDLINE

Výrazy ze slovníku MeSH: Melanoma*/surgery , Melanoma*/mortality , Melanoma*/pathology , Margins of Excision* , Subcutaneous Fat*/surgery , Subcutaneous Fat*/pathology , Skin Neoplasms*/surgery , Skin Neoplasms*/mortality , Skin Neoplasms*/pathology, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Aged ; Prognosis ; Adult ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Invasiveness ; Foot/surgery ; Disease-Free Survival ; Aged, 80 and over