Výsledky vyhľadávania - "String Database Version 12.0"

Molecular Architecture of Duchenne Muscular Dystrophy: Hub Gene Identification and Functional Pathway Analysis

Autori: Amna Makawi Somia Attaelseed Khalafallah Aymen Elfadil Abbas a ďalší

Prispievatelia: Amna Makawi Somia Attaelseed Khalafallah Aymen Elfadil Abbas a ďalší

Zdroj: Biomedical and Pharmacology Journal. 18:1695-1710

Predmety: Muscle Atrophy, Omim Database, Transcription Factor, Disease Exacerbation, Protein Expression, Gene Expression, Apoptosis, Duchenne Muscular Dystrophy, Functional Enrichment Analysis, Gene, Microrna, Dystrophin, Cell Infiltration, Go Consortium Enrichment Tool, Architecture, Down Regulation, Dystrophin Protein, Muscular Dystrophy, Protein Protein Interaction, Immune Response, Gene Regulatory Network, Genetic Transcription, Genecards Database, Enrichment Pathway, Extracellular Matrix, Extracellular Matrix Organization, Geo2r Tool, Differential Gene Expression, Limma Package R, Functional Pathway Analysis, Genetic Association, Network Analysis, Human, Signal Transduction, Bioinformatics, Gene Set Enrichment Analysis, Pathophysiology, Article, Rna Sequence, Life Expectancy, Kegg, Reactome Database, Hub Genes, Gene Identification, Molecular Architecture, Transcriptomics, Enrichment Pathways, Gene Expression Profiling, String Database Version 12.0, Differential Expression Analysis, Cytoscape Version 3.10.2, Validation Process, Gene Ontology, Mutation, Hub Gene

Prístupová URL adresa: https://hdl.handle.net/20.500.12831/25778
https://doi.org/10.13005/bpj/3203

Predicting interactome networks of up/down regulated proteins and drug-gene interaction analysis associated with peri-implantitis.

Autori: Asadzadeh, Azizeh Moattar, Fatemeh Shams Moshfegh, Azam

Zdroj: Dental Research Journal; Jan2025, Vol. 22 Issue 1, p1-7, 7p

Predmety: PROTEINS, DENTAL implants, COMPUTER software, PHARMACEUTICAL chemistry, PERI-implantitis, BIOINFORMATICS, GENE expression profiling, MICROARRAY technology, PROTEOMICS, PHARMACOGENOMICS, DRUG interactions, INDIVIDUALIZED medicine, BIOMARKERS, MOLECULAR pathology

A Novel Scaffold-Free Engineered Cartilage Using Combined Chondrocyte Pellets and Sheets in Chondrogenic Differentiation Medium.

Autori: Wongin-Sangphet, Sopita Sribenjarat, Pinprapha Chotiyarnwong, Pojchong a ďalší

Zdroj: Tissue Engineering & Regenerative Medicine; Dec2025, Vol. 22 Issue 8, p1141-1157, 17p

VEGFB is a potential therapeutic target for Alzheimer's disease: Insights from integrative multi-omics analysis.

Autori: Ye, Hongyu Zhuang, Caixiang Jin, Ziyang a ďalší

Zdroj: Journal of Alzheimer's Disease; Dec2025, Vol. 108 Issue 3, p1073-1087, 15p

Predmety: ALZHEIMER'S disease, DRUG target, MULTIOMICS, DRUG development, GENE expression, VASCULAR endothelial growth factors, GENETIC regulation, MENDELIAN randomization

Variable steady inflammation and inflammatory responses in precision-cut lung slices from various IPF lung Regions.

Autori: Machahua, Carlos Marti, Thomas M. Kewalramani, Namrata a ďalší

Zdroj: Respiratory Research; 11/28/2025, Vol. 26 Issue 1, p1-18, 18p

Serum proteomics and machine learning identify PSMD11 as a prognostic biomarker in severe fever with thrombocytopenia syndrome.

Autori: Zhao, Chenxi Ge, Ziruo Wang, Ranran a ďalší

Zdroj: Frontiers in Immunology; 2025, p1-13, 13p

Predmety: PROGNOSIS, VIRAL load, PROTEOMICS, MACHINE learning, MULTIPLE organ failure, HEMORRHAGIC fever

Application of VHH-Immobilized Cryogel-Based Immunoaffinity Chromatography for Isolation of Extracellular Vesicles.

Autori: Terzić, Jovana Filipović, Lidija Mitić, Ninoslav a ďalší

Zdroj: Molecules; Nov2025, Vol. 30 Issue 22, p4337, 20p

The Emerging Role of FAM171A2 in Gynecological Malignancies: Bioinformatic Insights from UCEC and Ovarian Cancer.

Autori: Soylemez, Sibel Ayan, Durmus

Zdroj: International Journal of Molecular Sciences; Nov2025, Vol. 26 Issue 22, p11126, 26p

Predmety: OVARIAN cancer, GYNECOLOGIC cancer, GENETIC transcription regulation, ENDOMETRIAL cancer, GENE expression, BIOINFORMATICS, GENE regulatory networks, GENES

The RNA-binding protein RBM39 scaffolds an m⁶A-dependent RNA decay complex that destabilizes Tat transcripts and restricts HIV-1 reactivation.

Autori: Deng, Xiaohui Xie, Siyi Zhou, Mo a ďalší

Zdroj: PLoS Biology; 11/11/2025, Vol. 23 Issue 11, p1-25, 25p

Predmety: RNA-binding proteins, HIV infections, DRUG target, VIRUS reactivation, NUCLEIC acids

In-silico discovery of druggable molecular signatures that drive dengue fever to severe dengue fever highlighting common pathogenesis through single-cell RNA-Seq analysis.

Autori: Al Noman, Md. Latif, Md. Abdul Ahmed, Md. Foysal a ďalší

Zdroj: Scientific Reports; 11/11/2025, Vol. 15 Issue 1, p1-20, 20p

Predmety: DENGUE, DRUG discovery, CELL populations, THERAPEUTICS, GENE expression, RNA sequencing, BIOMARKERS

A frameshift variant in activity-dependent neuroprotective protein (ADNP) causes nucleocytoskeletal alterations in a dizygotic male twin: a case study.

Autori: D'Incal, Claudio Peter Van Dijck, Anke Annear, Dale John a ďalší

Zdroj: Clinical Epigenetics; 11/10/2025, Vol. 17 Issue 1, p1-12, 12p

Predmety: AUTISM, WNT signal transduction, NEURAL development, ZINC-finger proteins, INTELLECTUAL disabilities, DNA methylation, DIZYGOTIC twins, MOLECULAR genetics

Identification of post-translational modification-related biomarkers in ischemic stroke using bioinformatics and machine learning.

Autori: Bian, Xiaonan Fu, Haiyang Sun, Wenqiang a ďalší

Zdroj: Scientific Reports; 11/10/2025, Vol. 15 Issue 1, p1-18, 18p

Predmety: ISCHEMIC stroke, POST-translational modification, MACHINE learning, DIAGNOSIS, GENE expression, DRUG target, BIOINFORMATICS, BIOMARKERS

Polydatin as a potential therapeutic agent for migraine: mechanistic insights from experimental, network pharmacology and molecular docking studies.

Autori: Anwar, Maira Badshah, Ismail Altaf, Reem a ďalší

Zdroj: Future Journal of Pharmaceutical Sciences; 11/7/2025, Vol. 11 Issue 1, p1-19, 19p

Predmety: MIGRAINE, NITRIC oxide, CALCITONIN gene-related peptide, PHARMACOLOGY, BIOACTIVE compounds, OXIDATIVE stress, THERAPEUTICS, MOLECULAR docking

Intersectin1/cdc42 signaling regulates methamphetamine-induced neuronal remodeling in the hippocampus.

Autori: Terceiro, Ana Filipa Lobo, Andrea Socodato, Renato a ďalší

Zdroj: Cellular & Molecular Life Sciences; 11/6/2025, Vol. 82 Issue 1, p1-21, 21p

Development of a diagnostic model for ovarian cancer based on machine learning algorithms and functional analysis of key biomarker SOX17.

Autori: Geng, Xueyan Yin, Maopeng Zhao, Hongxi a ďalší

Zdroj: Journal of Ovarian Research; 11/4/2025, Vol. 18 Issue 1, p1-13, 13p

Predmety: OVARIAN cancer, MACHINE learning, TUMOR microenvironment, PREDICTION models, TUMOR markers, GENE expression profiling, SOX transcription factors, BIOMARKERS

Integrated summary data-based Mendelian randomization and colocalization analysis reveals TNNT3 as a target of Deer-Antler-Ginseng-formula for triple-negative breast cancer.

Autori: Jia, Jianling Ma, Yuan Wu, Di a ďalší

Zdroj: Discover Oncology; 11/4/2025, Vol. 16 Issue 1, p1-19, 19p

Predmety: TRIPLE-negative breast cancer, DRUG target, TROPONIN, MENDELIAN randomization, GENE expression profiling

Kmt2c / Mll3 Haploinsufficiency Causes Autism-like Behavioral Deficits in Mice.

Autori: Ma, Kaijie Webb, Maria Hayder, Haniya a ďalší

Zdroj: Biomolecules (2218-273X); Nov2025, Vol. 15 Issue 11, p1547, 14p

Predmety: AUTISM, NEURAL development, HISTONE methyltransferases, DEVELOPMENTAL delay, ANIMAL disease models, GENETIC disorders, GENETIC testing

Genetic variation in the Nr1d1 transcription factor binding site shapes metabolism‐related protein networks associated with cognitive resilience in an Alzheimer's disease mouse reference panel.

Autori: Chen, Yu Stevenson, Tamara K. Cao, Yiding a ďalší

Zdroj: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Nov2025, Vol. 21 Issue 11, p1-17, 17p

Differential Expression of Antioxidant and Oxidant Pathways in Chronic Rhinosinusitis Without Nasal Polyps.

Autori: Tsai, Yih-Jeng Shieh, Jiunn-Min Ma, Ming-Chieh a ďalší

Zdroj: Antioxidants; Nov2025, Vol. 14 Issue 11, p1292, 17p

The study of Alzheimer's disease risk diagnosis based on natural killer cell marker genes in the multi-omics data.

Autori: Chen, Xiaorong Hu, Fuyan Chi, Qingjia a ďalší

Zdroj: Journal of Alzheimer's Disease; 2025 Suppl 1, Vol. 108, pS274-S292, 19p

Predmety: ALZHEIMER'S disease, BIOMARKERS, RNA sequencing, BIOLOGICAL databases, FEATURE selection, PHYSIOLOGY, PREDICTION models, KILLER cells