Výsledky vyhľadávania - "Spiro Compounds pharmacology"

Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205

Autori: Eggo, MC Lewis, AE Wong, BCY a ďalší

Zdroj: Cellular Signalling. 17:253-262

Predmety: 0301 basic medicine, Apoptosis, Tumor Necrosis Factor-alpha - pharmacology, Cysteine Proteinase Inhibitors - pharmacology, Dipeptides - pharmacology, Acetophenones - pharmacology, Amino Acid Chloromethyl Ketones, Benzopyrans - pharmacology, Acetamides, Phenanthridines - pharmacology, Protein Kinase C - metabolism - physiology, 0303 health sciences, Tumor, Indomethacin - pharmacology, Calpain, Caspase 3, Colonic Neoplasms - chemistry - metabolism - pathology, Cell Cycle, Amino Acid Chloromethyl Ketones - pharmacology, Dipeptides, Flow Cytometry, Caspase Inhibitors, 3. Good health, Protein Kinase C-delta, Caspases, Colonic Neoplasms, Enzyme Inhibitors - pharmacology, Pyrans - pharmacology, Antineoplastic Agents, DNA Fragmentation, Cysteine Proteinase Inhibitors, Cell Line, Calpain - antagonists & inhibitors, Tetradecanoylphorbol Acetate - pharmacology, 03 medical and health sciences, Alkaloids, Cell Line, Tumor, Cell Cycle - drug effects, Humans, Benzopyrans, DNA Fragmentation - drug effects, Cell Proliferation, Benzophenanthridines, Phosphorylation - drug effects, Acetamides - pharmacology, Spiro Compounds - pharmacology, Acetophenones, Enzyme Activation, Kinetics, Caspases - antagonists & inhibitors - metabolism - physiology, Cell Proliferation - drug effects, Antineoplastic Agents - pharmacology, Histones - metabolism

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/15494216
http://www.ncbi.nlm.nih.gov/pubmed/15494216
https://core.ac.uk/display/37907837
http://www.sciencedirect.com/science/article/pii/S0898656804001421
http://hub.hku.hk/handle/10722/76368
https://www.sciencedirect.com/science/article/pii/S0898656804001421#!
http://europepmc.org/abstract/MED/15494216
http://hdl.handle.net/10722/76368

Spiro[pyrrolidine-3, 3´-oxindole] as potent anti-breast cancer compounds: Their design, synthesis, biological evaluation and cellular target identification

Autori: Hati, Santanu Tripathy, Sayantan Dutta, Pratip Kumar a ďalší

Zdroj: Sci Rep

Predmety: 0301 basic medicine, Indoles, Pyrrolidines, Apoptosis - drug effects, Antineoplastic Agents - chemistry, Antineoplastic Agents, Apoptosis, Breast Neoplasms, Molecular Dynamics Simulation, 01 natural sciences, Article, Cercopithecus aethiops, Breast Neoplasms - pathology, 03 medical and health sciences, Chlorocebus aethiops, Animals, Humans, Spiro Compounds, Antineoplastic Agents - chemical synthesis, Cell Proliferation, Pyrrolidines - chemistry, Molecular Structure, Spiro Compounds - chemistry, Spiro Compounds - pharmacology, Breast Neoplasms - metabolism, Oxindoles, 0104 chemical sciences, 3. Good health, Indoles - chemistry, Drug Design, COS Cells, Antineoplastic Agents - pharmacology, Cell Proliferation - drug effects, MCF-7 Cells, Spiro Compounds - chemical synthesis, Female

Prístupová URL adresa: https://www.nature.com/articles/srep32213.pdf
https://pubmed.ncbi.nlm.nih.gov/27573798
http://ui.adsabs.harvard.edu/abs/2016NatSR...632213H/abstract
https://www.ncbi.nlm.nih.gov/pubmed/27573798
https://www.nature.com/articles/srep32213
https://www.nature.com/articles/srep32213.pdf
https://pubmed.ncbi.nlm.nih.gov/27573798/
https://europepmc.org/article/MED/27573798

[Action mechanism of anticonvulsant and anti-immobility (forced swim) effects of 3', 4'-dihydro-N, N-dimethylspiro-[9H-fluorene-9, 2' (5'H) furane]-3'-methanamine (AE37F)]

Autori: Vamvakides, A. Antoniou, K. Daifoti, Z.

Zdroj: Annales pharmaceutiques francaises. 62(1)

Predmety: 0301 basic medicine, Serotonin, Motor Activity/drug effects, Receptors, N-Methyl-D-Aspartate/drug effects, Pentylenetetrazole/antagonists & inhibitors/pharmacology, Convulsants, Muscarinic Antagonists, Swimming/psychology, Motor Activity, Receptors, N-Methyl-D-Aspartate, Serotonin/metabolism, Anticonvulsants/*pharmacology, 03 medical and health sciences, Mice, 0302 clinical medicine, Amantadine, Animals, Spiro Compounds, Furans, Swimming, Brain Chemistry, Spiro Compounds/*pharmacology, Furans/*pharmacology, Hydroxyindoleacetic Acid, Muscarinic Antagonists/chemical synthesis/pharmacology, 3. Good health, Rats, Hydroxyindoleacetic Acid/metabolism, Amantadine/pharmacology, Convulsants/pharmacology, Pentylenetetrazole, Anticonvulsants, Brain Chemistry/drug effects

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/14747773
http://olympias.lib.uoi.gr/jspui/handle/123456789/24127