Search Results - "Sleep Deprivation"

Chronic sleep deprivation induces depression- and Alzheimer's disease-like changes in adult and ageing wild-type and Fat-1 transgenic mice.

Authors: Niazi NUK Yang Z Zhang Y et al.

Source: Prostaglandins, leukotrienes, and essential fatty acids [Prostaglandins Leukot Essent Fatty Acids] 2025 Dec; Vol. 207, pp. 102699. Date of Electronic Publication: 2025 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 8802730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2823 (Electronic) Linking ISSN: 09523278 NLM ISO Abbreviation: Prostaglandins Leukot Essent Fatty Acids Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/complications , Sleep Deprivation*/metabolism , Sleep Deprivation*/genetics , Alzheimer Disease*/metabolism , Alzheimer Disease*/etiology , Alzheimer Disease*/genetics , Depression*/metabolism , Depression*/etiology , Depression*/genetics , Aging*/metabolism, Animals ; Mice ; Mice, Transgenic ; Male ; Disease Models, Animal ; Toll-Like Receptor 4/metabolism ; Brain/metabolism ; Fatty Acids, Omega-3/metabolism ; Mice, Inbred C57BL ; Cadherins

Brain connectivity changes associated with acute sleep deprivation: a systematic review.

Authors: Hosang S Wong K Mlinarevic D et al.

Source: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2025 Dec; Vol. 46 (12), pp. 6457-6477. Date of Electronic Publication: 2025 Oct 13.

Publication Type: Journal Article; Systematic Review; Review

Journal Info: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100959175 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3478 (Electronic) Linking ISSN: 15901874 NLM ISO Abbreviation: Neurol Sci Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/physiopathology , Sleep Deprivation*/diagnostic imaging , Brain*/physiopathology , Brain*/diagnostic imaging , Nerve Net*/physiopathology , Nerve Net*/diagnostic imaging , Connectome*, Humans

Sleep deprivation exacerbates experimental colitis via down-regulating the clock gene Per2.

Authors: Jiang X Wu P Chen H et al.

Source: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 2), pp. 117224. Date of Electronic Publication: 2025 Aug 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Period Circadian Proteins*/genetics , Period Circadian Proteins*/metabolism , Period Circadian Proteins*/biosynthesis , Period Circadian Proteins*/antagonists & inhibitors , Colitis*/metabolism , Colitis*/chemically induced , Colitis*/genetics , Colitis*/pathology , Sleep Deprivation*/metabolism , Sleep Deprivation*/genetics , Sleep Deprivation*/complications , Down-Regulation*/physiology, Animals ; Mice ; Mice, Inbred C57BL ; Dextran Sulfate/toxicity ; Male ; Mice, Knockout ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism

Sleep & Wellness for the Otolaryngologist.

Authors: Erickson TS Durr ML

Source: Otolaryngologic clinics of North America [Otolaryngol Clin North Am] 2025 Dec; Vol. 58 (6), pp. 993-1002. Date of Electronic Publication: 2025 Jul 22.

Publication Type: Journal Article; Review

Journal Info: Publisher: W B Saunders Country of Publication: United States NLM ID: 0144042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8259 (Electronic) Linking ISSN: 00306665 NLM ISO Abbreviation: Otolaryngol Clin North Am Subsets: MEDLINE

MeSH Terms: Burnout, Professional*/prevention & control , Burnout, Professional*/etiology , Sleep Deprivation*/prevention & control , Sleep Deprivation*/psychology , Otolaryngologists*/psychology , Sleep* , Otolaryngology*, Humans ; Sleep Quality ; Work Schedule Tolerance

Irreversible male infertility from sleep restriction: A dual hit on testicular steroidogenesis and Keap1-Nrf2-mediated antioxidant defense.

Authors: Chen K Luo F Huang X et al.

Source: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2025 Dec; Vol. 138, pp. 109083. Date of Electronic Publication: 2025 Oct 22.

Publication Type: Journal Article

Journal Info: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

MeSH Terms: Testis*/metabolism , Testis*/pathology , Kelch-Like ECH-Associated Protein 1*/metabolism , Infertility, Male*/etiology , Infertility, Male*/metabolism , NF-E2-Related Factor 2*/metabolism , Testosterone*/biosynthesis , Sleep Deprivation*/metabolism , Sleep Deprivation*/complications, Male ; Animals ; Mice, Inbred ICR ; Antioxidants/metabolism ; Mice ; Apoptosis ; Spermatozoa ; Oxidative Stress

Bidirectional Predictors Between Neurobehavioural Measures During Total Sleep Deprivation and Baseline and Recovery Sleep Measures.

Authors: Pasetes LN Goel N

Source: Journal of sleep research [J Sleep Res] 2025 Dec; Vol. 34 (6), pp. e70031. Date of Electronic Publication: 2025 Mar 08.

Publication Type: Journal Article

Journal Info: Publisher: Published on behalf of the European Sleep Research Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9214441 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2869 (Electronic) Linking ISSN: 09621105 NLM ISO Abbreviation: J Sleep Res Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/physiopathology , Sleep Deprivation*/psychology , Sleep*/physiology , Psychomotor Performance*/physiology, Humans ; Female ; Male ; Actigraphy ; Adult ; Young Adult ; Fatigue/physiopathology ; Sleepiness

Sleep deprivation-induced cognitive impairment: Unraveling the role of neuroinflammation.

Authors: Yuan XL Wang CY

Source: Experimental neurology [Exp Neurol] 2025 Dec; Vol. 394, pp. 115419. Date of Electronic Publication: 2025 Aug 14.

Publication Type: Journal Article; Review

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/complications , Sleep Deprivation*/metabolism , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/metabolism , Neuroinflammatory Diseases*/metabolism , Neuroinflammatory Diseases*/etiology, Humans ; Animals ; Brain/metabolism

[Study on the innate immune regulatory mechanism of transcutaneous electrical acupoint stimulation in sleep-deprived rats based on TLR4/MyD88/NF-κB signaling pathway].

Authors: Zhang Y Xue Y Wang D et al.

Source: Zhen ci yan jiu = Acupuncture research [Zhen Ci Yan Jiu] 2025 Nov 25; Vol. 50 (11), pp. 1276-1285.

Publication Type: English Abstract; Journal Article

Journal Info: Publisher: Institute Of Acupuncture And Moxibustion Country of Publication: China NLM ID: 8507710 Publication Model: Print Cited Medium: Print ISSN: 1000-0607 (Print) Linking ISSN: 10000607 NLM ISO Abbreviation: Zhen Ci Yan Jiu Subsets: MEDLINE

MeSH Terms: Toll-Like Receptor 4*/genetics , Toll-Like Receptor 4*/immunology , Acupuncture Points* , Myeloid Differentiation Factor 88*/genetics , Myeloid Differentiation Factor 88*/immunology , NF-kappa B*/genetics , NF-kappa B*/immunology , Sleep Deprivation*/immunology , Sleep Deprivation*/genetics , Sleep Deprivation*/therapy , Immunity, Innate* , Transcutaneous Electric Nerve Stimulation*, Animals ; Rats ; Rats, Sprague-Dawley ; Signal Transduction ; Male ; Humans

Bidirectional Effects of Sleep Deprivation Associated with Parkinson's Disease on Behavior, Oxidative Stress, and Energy Metabolism in Male and Female Rats.

Authors: Mathia GB Mondo GS Pedro LC et al.

Source: Molecular neurobiology [Mol Neurobiol] 2025 Nov 24; Vol. 63 (1), pp. 161. Date of Electronic Publication: 2025 Nov 24.

Publication Type: Journal Article

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/metabolism , Sleep Deprivation*/complications , Sleep Deprivation*/physiopathology , Oxidative Stress*/physiology , Energy Metabolism*/physiology , Parkinson Disease*/metabolism , Parkinson Disease*/complications , Parkinson Disease*/physiopathology , Behavior, Animal* , Sex Characteristics*, Animals ; Rats, Wistar ; Female ; Male ; Rats ; Mitochondria/metabolism ; Oxidopamine ; Brain/metabolism

Targeting Oxidative Stress and Neuroinflammation: Epigallocatechin-3-gallate-Selenium Nanoparticles Mitigate Sleep Deprivation-Induced Cortical Impairment.

Authors: Lutfy RH Ashour AM Khames A et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 19; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Catechin*/analogs & derivatives , Catechin*/pharmacology , Catechin*/chemistry , Oxidative Stress*/drug effects , Sleep Deprivation*/complications , Sleep Deprivation*/drug therapy , Sleep Deprivation*/metabolism , Nanoparticles*/chemistry , Selenium*/chemistry , Selenium*/pharmacology , Neuroinflammatory Diseases*/drug therapy , Neuroinflammatory Diseases*/metabolism , Neuroinflammatory Diseases*/etiology , Cerebral Cortex*/drug effects , Cerebral Cortex*/metabolism , Cerebral Cortex*/pathology, Animals ; Rats ; Male ; Neuroprotective Agents/pharmacology ; Antioxidants/pharmacology ; Rats, Wistar

Exploratory development of biomarkers for neurobehavioral performance impairment during sleep loss: comparison across multiple types of sleep deprivation.

Authors: Uyhelji HA Nicholson SJ Nesthus TE et al.

Source: BMC genomics [BMC Genomics] 2025 Nov 14; Vol. 26 (1), pp. 1043. Date of Electronic Publication: 2025 Nov 14.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/physiopathology , Sleep Deprivation*/genetics , Biomarkers*/metabolism, Humans ; Male ; Female ; Adult ; Young Adult ; Psychomotor Performance ; Fatigue/genetics ; Polysomnography ; Middle Aged ; Transcriptome

Acute sleep deprivation induces hyperalgesia through P2X4-mediated microglial activation in mice.

Authors: Huang S Cheng W Lai P et al.

Source: European journal of medical research [Eur J Med Res] 2025 Nov 11; Vol. 30 (1), pp. 1106. Date of Electronic Publication: 2025 Nov 11.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9517857 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-783X (Electronic) Linking ISSN: 09492321 NLM ISO Abbreviation: Eur J Med Res Subsets: MEDLINE

MeSH Terms: Microglia*/metabolism , Microglia*/drug effects , Sleep Deprivation*/complications , Sleep Deprivation*/metabolism , Hyperalgesia*/etiology , Hyperalgesia*/metabolism , Receptors, Purinergic P2X4*/metabolism, Animals ; Mice ; Male ; Cytokines/metabolism ; Mice, Inbred C57BL

Effects of acute sleep deprivation and recovery sleep on cognitive performance in depressed individuals.

Authors: Larson O Basner M Rao H et al.

Source: Journal of psychiatric research [J Psychiatr Res] 2025 Nov; Vol. 191, pp. 198-205. Date of Electronic Publication: 2025 Sep 26.

Publication Type: Journal Article

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0376331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1379 (Electronic) Linking ISSN: 00223956 NLM ISO Abbreviation: J Psychiatr Res Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/complications , Sleep Deprivation*/physiopathology , Depression*/complications, Humans ; Male ; Female ; Adult ; Middle Aged ; Neuropsychological Tests ; Young Adult

Sleep Deprivation Aggravates Periodontitis Through Trigeminal-Periodontal Neuroimmune Pathway Mediated by the AChE-ACh-α7nAChR Axis.

Authors: Liu K Huang Q Yang M et al.

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Nov; Vol. 12 (43), pp. e00945. Date of Electronic Publication: 2025 Aug 14.

Publication Type: Journal Article

Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

MeSH Terms: alpha7 Nicotinic Acetylcholine Receptor*/metabolism , Sleep Deprivation*/complications , Sleep Deprivation*/metabolism , Sleep Deprivation*/immunology , Periodontitis*/metabolism , Periodontitis*/immunology , Acetylcholine*/metabolism , Acetylcholinesterase*/metabolism , Neuroimmunomodulation*/physiology, Animals ; Mice ; Male ; Humans ; Macrophages/metabolism ; Disease Models, Animal ; Mice, Inbred C57BL ; Female ; Electroacupuncture/methods ; Trigeminal Ganglion/metabolism ; Trigeminal Ganglion/immunology

High-intensity interval training (HIIT) and lactate protect against sleep deprivation-induced memory impairment: Role of the PKA-CREB-BDNF-Cofilin signaling pathway.

Authors: Movahed A Aminizadeh S Marefati H et al.

Source: Physiology & behavior [Physiol Behav] 2025 Nov 01; Vol. 301, pp. 115076. Date of Electronic Publication: 2025 Aug 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0151504 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-507X (Electronic) Linking ISSN: 00319384 NLM ISO Abbreviation: Physiol Behav Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/complications , Sleep Deprivation*/metabolism , High-Intensity Interval Training*/methods , Signal Transduction*/drug effects , Signal Transduction*/physiology , Memory Disorders*/etiology , Memory Disorders*/prevention & control , Memory Disorders*/metabolism , Memory Disorders*/therapy , Lactic Acid*/pharmacology, Animals ; Male ; Brain-Derived Neurotrophic Factor/metabolism ; Rats, Wistar ; Cyclic AMP Response Element-Binding Protein/metabolism ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Rats ; Hippocampus/metabolism ; Hippocampus/drug effects ; Actin Depolymerizing Factors/metabolism ; Maze Learning/drug effects ; Maze Learning/physiology

Effect of 24-h and 36-h acute total sleep deprivation on human attention: An activation likelihood estimation meta-analysis.

Authors: Shao Y Chen J Zhong X et al.

Source: International journal of psychophysiology : official journal of the International Organization of Psychophysiology [Int J Psychophysiol] 2025 Nov; Vol. 217, pp. 113252. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article; Meta-Analysis; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8406214 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7697 (Electronic) Linking ISSN: 01678760 NLM ISO Abbreviation: Int J Psychophysiol Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/physiopathology , Sleep Deprivation*/diagnostic imaging , Attention*/physiology , Nerve Net*/diagnostic imaging , Nerve Net*/physiopathology , Cerebral Cortex*/diagnostic imaging , Cerebral Cortex*/physiopathology, Humans ; Magnetic Resonance Imaging ; Time Factors ; Likelihood Functions

L-theanine prevents myocardial injury in sleep‑deprived mice by suppressing ferroptosis through SIRT1.

Authors: Huang X Lu X Wu Y et al.

Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Nov; Vol. 398 (11), pp. 15443-15457. Date of Electronic Publication: 2025 May 06.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

MeSH Terms: Sirtuin 1*/metabolism , Ferroptosis*/drug effects , Glutamates*/pharmacology , Glutamates*/therapeutic use , Sleep Deprivation*/complications , Sleep Deprivation*/drug therapy , Sleep Deprivation*/metabolism , Cardiotonic Agents*/pharmacology , Antioxidants*/pharmacology, Animals ; Male ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/pathology ; Myocytes, Cardiac/metabolism ; Cell Line ; Mice ; Reactive Oxygen Species/metabolism ; Rats ; Oxidative Stress/drug effects ; Mice, Inbred C57BL

Sleep deprivation and risk for Parkinson's disease: evidence and therapeutic implications.

Authors: Zhou T Ye W Chen B et al.

Source: Journal of neurology [J Neurol] 2025 Oct 30; Vol. 272 (11), pp. 740. Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE

MeSH Terms: Parkinson Disease*/epidemiology , Parkinson Disease*/etiology , Parkinson Disease*/therapy , Parkinson Disease*/prevention & control , Sleep Deprivation*/complications , Sleep Deprivation*/therapy , Sleep Deprivation*/epidemiology, Humans ; Risk Factors

Sleep deprivation disrupts vestibular compensation by activating TLR4/NF-κB/NLRP3 signalling in the deafferented vestibular nuclei.

Authors: Li Z Lai J Li Y et al.

Source: Brain research bulletin [Brain Res Bull] 2025 Oct 15; Vol. 231, pp. 111550. Date of Electronic Publication: 2025 Sep 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2747 (Electronic) Linking ISSN: 03619230 NLM ISO Abbreviation: Brain Res Bull Subsets: MEDLINE

MeSH Terms: Toll-Like Receptor 4*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Sleep Deprivation*/metabolism , Sleep Deprivation*/physiopathology , Vestibular Nuclei*/metabolism , NF-kappa B*/metabolism , Vestibule, Labyrinth*/metabolism, Animals ; Mice ; Signal Transduction/physiology ; Male ; Mice, Inbred C57BL ; Microglia/metabolism ; Neuronal Plasticity/physiology ; Minocycline/pharmacology

Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine.

Authors: Wang Z Zhou L Zheng Y et al.

Source: Journal of translational medicine [J Transl Med] 2025 Oct 15; Vol. 23 (1), pp. 1106. Date of Electronic Publication: 2025 Oct 15.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

MeSH Terms: Sleep Deprivation*/microbiology , Sleep Deprivation*/metabolism , Homeostasis*/drug effects , Gastrointestinal Microbiome*/drug effects , Taurine*/metabolism , Taurine*/pharmacology , Nuclear Receptor Subfamily 1, Group D, Member 1*/metabolism , Intestines*/microbiology , Intestines*/pathology, Animals ; Male ; Mice, Inbred C57BL ; Intestinal Mucosa/pathology ; Intestinal Mucosa/metabolism ; Mice ; Fecal Microbiota Transplantation ; Colon/pathology