Search Results - "Skin Aging"

Grape Seed Extract NSPCC1 Counteracts Mouse Skin Aging via Modulating MAPK and AMPK Pathways.

Authors: Zhang Z Xue Z Wang Y et al.

Source: Journal of food science [J Food Sci] 2025 Dec; Vol. 90 (12), pp. e70620.

Publication Type: Journal Article

Journal Info: Publisher: Wiley on behalf of the Institute of Food Technologists Country of Publication: United States NLM ID: 0014052 Publication Model: Print Cited Medium: Internet ISSN: 1750-3841 (Electronic) Linking ISSN: 00221147 NLM ISO Abbreviation: J Food Sci Subsets: MEDLINE

MeSH Terms: Skin Aging*/drug effects , Skin Aging*/radiation effects , Grape Seed Extract*/pharmacology , AMP-Activated Protein Kinases*/metabolism , AMP-Activated Protein Kinases*/genetics , MAP Kinase Signaling System*/drug effects, Animals ; Mice ; Skin/drug effects ; Skin/metabolism ; Skin/radiation effects ; Ultraviolet Rays/adverse effects ; Proanthocyanidins/pharmacology ; Antioxidants/pharmacology ; Male

Single-Cell Atlas of Aging Human Skin Reveals FOSB-Related Transcriptional Programs and Druggable Targets.

Authors: Zhang Y Wang Y Lyu D et al.

Source: Journal of cosmetic dermatology [J Cosmet Dermatol] 2025 Dec; Vol. 24 (12), pp. e70569.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Science Country of Publication: England NLM ID: 101130964 Publication Model: Print Cited Medium: Internet ISSN: 1473-2165 (Electronic) Linking ISSN: 14732130 NLM ISO Abbreviation: J Cosmet Dermatol Subsets: MEDLINE

MeSH Terms: Skin Aging*/genetics , Skin Aging*/drug effects , Proto-Oncogene Proteins c-fos*/genetics , Proto-Oncogene Proteins c-fos*/metabolism , Skin*/cytology , Skin*/drug effects , Skin*/metabolism, Humans ; Single-Cell Analysis ; Gene Regulatory Networks ; Aged ; Adult ; RNA-Seq ; Middle Aged ; Female ; Male ; Metallothionein/genetics ; Metallothionein/metabolism ; Young Adult

Human collagen III mRNA therapy for effective skin rejuvenation.

Authors: Zhang J Chen S Yang J et al.

Source: Journal of translational medicine [J Transl Med] 2025 Nov 13; Vol. 23 (1), pp. 1283. Date of Electronic Publication: 2025 Nov 13.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

MeSH Terms: RNA, Messenger*/genetics , RNA, Messenger*/metabolism , RNA, Messenger*/therapeutic use , Skin Aging*/radiation effects , Skin Aging*/genetics , Rejuvenation* , Skin*/pathology , Skin*/radiation effects , Collagen Type III*/genetics , Collagen Type III*/metabolism , Collagen Type III*/therapeutic use, Humans ; Animals ; Ultraviolet Rays ; Cell Proliferation ; Apoptosis ; Fibroblasts/metabolism ; Cell Movement ; Cellular Senescence ; Oxidative Stress ; Mice

Skin microbiome and skin aging: emerging strategies for manipulation.

Authors: Wang Z Yuan F Zhong X et al.

Source: Microbiological research [Microbiol Res] 2025 Nov; Vol. 300, pp. 128285. Date of Electronic Publication: 2025 Jul 24.

Publication Type: Journal Article; Review

Journal Info: Publisher: G. Fischer Country of Publication: Germany NLM ID: 9437794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0623 (Electronic) Linking ISSN: 09445013 NLM ISO Abbreviation: Microbiol Res Subsets: MEDLINE

MeSH Terms: Skin Aging*/radiation effects , Skin Aging*/physiology , Microbiota*/radiation effects , Microbiota*/physiology , Skin*/microbiology , Skin*/radiation effects, Humans ; Ultraviolet Rays/adverse effects ; Aging ; Animals ; Skin Microbiome

A novel polypeptide inhibitor of MMP-1 attenuates the UVA-mediated skin aging.

Authors: Tang PX Li JX Guo C et al.

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Oct 30; Vol. 786, pp. 152681. Date of Electronic Publication: 2025 Sep 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH Terms: Skin Aging*/drug effects , Skin Aging*/radiation effects , Ultraviolet Rays*/adverse effects , Matrix Metalloproteinase 1*/metabolism , Matrix Metalloproteinase Inhibitors*/pharmacology , Matrix Metalloproteinase Inhibitors*/chemistry , Peptides*/pharmacology , Peptides*/chemistry, Humans ; Cellular Senescence/drug effects ; Cellular Senescence/radiation effects ; Cell Line ; Skin/drug effects ; Skin/radiation effects ; Cell Proliferation/drug effects ; Cell Proliferation/radiation effects ; Apoptosis/drug effects ; Apoptosis/radiation effects ; Fibroblasts/drug effects ; Fibroblasts/radiation effects ; Reactive Oxygen Species/metabolism

Arazyme prevents skin aging through regulation of matrix metalloproteinase and collagen synthesis.

Authors: Kim JH Lee H Son KH et al.

Source: Enzyme and microbial technology [Enzyme Microb Technol] 2025 Oct; Vol. 190, pp. 110695. Date of Electronic Publication: 2025 Jun 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8003761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0909 (Electronic) Linking ISSN: 01410229 NLM ISO Abbreviation: Enzyme Microb Technol Subsets: MEDLINE

MeSH Terms: Skin Aging*/drug effects , Skin Aging*/radiation effects , Collagen*/biosynthesis , Matrix Metalloproteinases*/metabolism , Matrix Metalloproteinases*/genetics, Humans ; Keratinocytes/drug effects ; Keratinocytes/metabolism ; Keratinocytes/radiation effects ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibroblasts/radiation effects ; Ultraviolet Rays ; Cellular Senescence/drug effects ; Oxidative Stress/drug effects ; Cell Line ; HaCaT Cells ; Matrix Metalloproteinase 1/metabolism ; Matrix Metalloproteinase 1/genetics ; Skin/drug effects ; Signal Transduction/drug effects

Isolation and characterization of bioactive collagen peptides from sea bass scales and their anti-photoaging effects.

Authors: Liu D Ren Y Zhong S et al.

Source: Food chemistry [Food Chem] 2025 Dec 25; Vol. 496 (Pt 2), pp. 146779. Date of Electronic Publication: 2025 Oct 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH Terms: Bass* , Collagen*/chemistry , Collagen*/pharmacology , Collagen*/isolation & purification , Peptides*/isolation & purification , Peptides*/pharmacology , Peptides*/chemistry , Fish Proteins*/isolation & purification , Fish Proteins*/chemistry , Fish Proteins*/pharmacology , Skin Aging*/drug effects , Skin Aging*/radiation effects , Animal Scales*/chemistry, Animals ; Humans ; Ultraviolet Rays ; Reactive Oxygen Species/metabolism ; NF-kappa B/metabolism ; NF-kappa B/genetics ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Tandem Mass Spectrometry

Exopolysaccharide from Lacticaseibacillus rhamnosus IR06 as a potential postbiotics attenuates photoaging through regulation of MAPK and NF-κB signaling.

Authors: Kim JH Lee WJ Choi KY et al.

Source: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 16; Vol. 241, pp. 843-856. Date of Electronic Publication: 2025 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

MeSH Terms: Polysaccharides, Bacterial*/pharmacology , Polysaccharides, Bacterial*/chemistry , NF-kappa B*/metabolism , NF-kappa B*/genetics , Skin Aging*/drug effects , Skin Aging*/radiation effects , Lacticaseibacillus rhamnosus*/chemistry, Humans ; Ultraviolet Rays/adverse effects ; Reactive Oxygen Species/metabolism ; Keratinocytes/drug effects ; Keratinocytes/metabolism ; Keratinocytes/radiation effects ; Signal Transduction/drug effects ; MAP Kinase Signaling System/drug effects ; Probiotics ; Antioxidants/pharmacology ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism

Assessing the Submental and Neck Region.

Authors: Mariwalla K Fabi S Belkin D et al.

Source: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2025 Dec 01; Vol. 51 (12S), pp. S31-S37.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 9504371 Publication Model: Print Cited Medium: Internet ISSN: 1524-4725 (Electronic) Linking ISSN: 10760512 NLM ISO Abbreviation: Dermatol Surg Subsets: MEDLINE

MeSH Terms: Neck*/anatomy & histology , Skin Aging*/ethnology , Skin Aging*/physiology , Rejuvenation*, Humans ; Cosmetic Techniques

Tannic acid prevents UVB-induced skin photoaging by regulating ferroptosis through NRF2/SLC7A11/GPX4 signaling.

Authors: Chen Z Ye L Zhu L et al.

Source: Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2025 Dec; Vol. 273, pp. 113309. Date of Electronic Publication: 2025 Nov 15.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Sequoia Country of Publication: Switzerland NLM ID: 8804966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2682 (Electronic) Linking ISSN: 10111344 NLM ISO Abbreviation: J Photochem Photobiol B Subsets: MEDLINE

MeSH Terms: Ultraviolet Rays*/adverse effects , NF-E2-Related Factor 2*/metabolism , Skin Aging*/drug effects , Skin Aging*/radiation effects , Ferroptosis*/drug effects , Ferroptosis*/radiation effects , Tannins*/pharmacology , Tannins*/chemistry , Signal Transduction*/drug effects , Signal Transduction*/radiation effects , Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism, Animals ; Humans ; Mice ; Mice, Inbred BALB C ; Reactive Oxygen Species/metabolism ; Fibroblasts/metabolism ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Fibroblasts/radiation effects ; Oxidative Stress/drug effects ; Oxidative Stress/radiation effects ; Skin/radiation effects ; Skin/metabolism ; Skin/cytology ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Antioxidants ; Cell Line ; Polyphenols

Valorization and evaluation of acidic and neutral polysaccharides from Panax ginseng processing residues for the mitigating effects on skin aging.

Authors: Xiong B Liu R Zhi X et al.

Source: Food research international (Ottawa, Ont.) [Food Res Int] 2025 Dec; Vol. 221 (Pt 3), pp. 117462. Date of Electronic Publication: 2025 Sep 08.

Publication Type: Journal Article

Journal Info: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH Terms: Panax*/chemistry , Polysaccharides*/pharmacology , Polysaccharides*/chemistry , Polysaccharides*/isolation & purification , Skin Aging*/drug effects , Plant Extracts*/pharmacology , Plant Extracts*/chemistry, Animals ; Mice ; Antioxidants/pharmacology ; Oxidative Stress/drug effects ; Male ; Spectroscopy, Fourier Transform Infrared ; Ginsenosides

Cedrol prevents UVB-induced photoaging by restoring mitochondrial function, metabolic homeostasis, and skin barrier integrity in HaCaT cells.

Authors: Xu MR Lin CH Lee HH et al.

Source: Pharmaceutical biology [Pharm Biol] 2025 Dec; Vol. 63 (1), pp. 859-876. Date of Electronic Publication: 2025 Nov 10.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

MeSH Terms: Ultraviolet Rays*/adverse effects , Mitochondria*/drug effects , Mitochondria*/radiation effects , Mitochondria*/metabolism , Skin Aging*/drug effects , Skin Aging*/radiation effects, Humans ; HaCaT Cells ; Reactive Oxygen Species/metabolism ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Membrane Potential, Mitochondrial/drug effects ; Membrane Potential, Mitochondrial/radiation effects ; Homeostasis/drug effects ; Homeostasis/radiation effects ; Skin/drug effects ; Skin/radiation effects ; Skin/metabolism ; Keratinocytes/drug effects ; Keratinocytes/radiation effects ; Keratinocytes/metabolism ; Oxidative Stress/drug effects ; Oxidative Stress/radiation effects ; Adenosine Triphosphate/metabolism ; Antioxidants/pharmacology

A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study.

Authors: Shao H Wang L Wang Y et al.

Source: The Journal of dermatological treatment [J Dermatolog Treat] 2025 Dec; Vol. 36 (1), pp. 2585243. Date of Electronic Publication: 2025 Nov 10.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE

MeSH Terms: Skin Aging*/drug effects , Skin Aging*/radiation effects , Intense Pulsed Light Therapy*/adverse effects , Intense Pulsed Light Therapy*/methods , Skin Cream*/administration & dosage , Skin Cream*/chemistry , Emollients*/administration & dosage , Emollients*/chemistry, Humans ; Female ; Middle Aged ; Adult ; Male ; Patient Satisfaction ; Treatment Outcome ; Rejuvenation ; Aged ; Water Loss, Insensible/drug effects

Integrative Network Pharmacology and Proteomics Decipher the Immunomodulatory Mechanism of Sulforaphane Against Intrinsic Skin Aging.

Authors: Du X Yang X Zhang C et al.

Source: Molecular nutrition & food research [Mol Nutr Food Res] 2025 Dec; Vol. 69 (23), pp. e70281. Date of Electronic Publication: 2025 Oct 02.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101231818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1613-4133 (Electronic) Linking ISSN: 16134125 NLM ISO Abbreviation: Mol Nutr Food Res Subsets: MEDLINE

MeSH Terms: Isothiocyanates*/pharmacology , Skin Aging*/drug effects , Sulfoxides*/pharmacology, Animals ; Proteomics/methods ; Mice ; Network Pharmacology ; Skin/drug effects ; Mice, Inbred C57BL ; Male ; Signal Transduction/drug effects

Recent Clinical Advances of the Use of Three Kinds of Laser Systems Combined with a New Exosome-Based Postlaser Booster Solution.

Authors: Ricardo Galimberti D Gallo G Fusco I et al.

Source: Photobiomodulation, photomedicine, and laser surgery [Photobiomodul Photomed Laser Surg] 2025 Dec; Vol. 43 (12), pp. 611-618. Date of Electronic Publication: 2025 Jul 23.

Publication Type: Journal Article

Journal Info: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101734781 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2578-5478 (Electronic) Linking ISSN: 25785478 NLM ISO Abbreviation: Photobiomodul Photomed Laser Surg Subsets: MEDLINE

MeSH Terms: Skin Aging*/radiation effects , Skin Aging*/drug effects , Exosomes* , Low-Level Light Therapy*/methods , Lasers, Gas*/therapeutic use , Lasers, Solid-State*/therapeutic use , Cosmetic Techniques*, Humans ; Aged ; Middle Aged ; Female ; Adult ; Aged, 80 and over ; Male

Unlocking Longevity in Aesthetic Dermatology: Epigenetics, Aging, and Personalized Care.

Authors: Haykal D Flament F Mora P et al.

Source: International journal of dermatology [Int J Dermatol] 2025 Dec; Vol. 64 (12), pp. 2204-2214. Date of Electronic Publication: 2025 Mar 10.

Publication Type: Journal Article; Review

Journal Info: Publisher: Blackwell Science Country of Publication: England NLM ID: 0243704 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-4632 (Electronic) Linking ISSN: 00119059 NLM ISO Abbreviation: Int J Dermatol Subsets: MEDLINE

MeSH Terms: Skin Aging*/genetics , Skin Aging*/radiation effects , Epigenesis, Genetic* , Rejuvenation* , Precision Medicine*/methods , Longevity*/genetics , Aging*/genetics, Humans ; DNA Methylation ; Dermatology/methods ; Life Style ; Cosmetic Techniques

Clinical evaluation of skin aging: a systematic review.

Authors: Wang YC Ma SH Chang YT et al.

Source: Archives of gerontology and geriatrics [Arch Gerontol Geriatr] 2025 Dec; Vol. 139, pp. 105995. Date of Electronic Publication: 2025 Aug 18.

Publication Type: Journal Article; Systematic Review; Review

Journal Info: Publisher: Elsevier Biomedical Press Country of Publication: Netherlands NLM ID: 8214379 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6976 (Electronic) Linking ISSN: 01674943 NLM ISO Abbreviation: Arch Gerontol Geriatr Subsets: MEDLINE

MeSH Terms: Skin Aging*/physiology, Humans

Collagen peptides derived from sea bass scales (Lateolabrax maculatus) relieve photoaging through MAPK, NF-κB and TGF-β signaling pathways and modulating gut microbiota composition.

Authors: Liu D Ren Y Peng Y et al.

Source: Food research international (Ottawa, Ont.) [Food Res Int] 2025 Dec; Vol. 221 (Pt 4), pp. 117521. Date of Electronic Publication: 2025 Sep 16.

Publication Type: Journal Article

Journal Info: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH Terms: Skin Aging*/drug effects , Skin Aging*/radiation effects , Bass* , Gastrointestinal Microbiome*/drug effects , Collagen*/pharmacology , Collagen*/chemistry , Transforming Growth Factor beta*/metabolism , Peptides*/pharmacology , Animal Scales*/chemistry, Animals ; NF-kappa B/metabolism ; Mice ; Signal Transduction/drug effects ; Ultraviolet Rays/adverse effects ; Skin/radiation effects ; Skin/drug effects ; Mice, Nude ; Mitogen-Activated Protein Kinases/metabolism

Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial.

Authors: Kim J Lee SG Boo J et al.

Source: The Journal of dermatological treatment [J Dermatolog Treat] 2025 Dec; Vol. 36 (1), pp. 2504655. Date of Electronic Publication: 2025 Jun 04.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE

MeSH Terms: Skin Aging*/drug effects , Skin Aging*/radiation effects , Coumaric Acids*/administration & dosage , Rejuvenation* , Antioxidants*/administration & dosage , Ascorbic Acid*/administration & dosage , Vitamin E*/administration & dosage , Cosmetic Techniques*/instrumentation, Humans ; Middle Aged ; Double-Blind Method ; Female ; Prospective Studies ; Neck ; Adult ; Aged ; Male ; Treatment Outcome ; Needles ; Combined Modality Therapy/methods ; Skin/pathology ; Elastin/metabolism

Saponins from Dioscorea nipponinca Makino rehabilitate UVB-induced skin photoaging by inhibiting oxidative stress and apoptosis via targeting STAT3.

Authors: Cai Q Zhang Q Zhang Y et al.

Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Nov 25; Vol. 148, pp. 157452. Date of Electronic Publication: 2025 Oct 25.

Publication Type: Journal Article

Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

MeSH Terms: STAT3 Transcription Factor*/metabolism , Saponins*/pharmacology , Oxidative Stress*/drug effects , Skin Aging*/drug effects , Skin Aging*/radiation effects , Dioscorea*/chemistry, Apoptosis/drug effects ; Ultraviolet Rays/adverse effects ; Animals ; Humans ; Mice ; HaCaT Cells ; Molecular Docking Simulation ; Mice, Inbred C57BL ; Skin/drug effects