Suchergebnisse - "Skin"

Beyond the Skin Surface: Melanocyte Biology and the Spectrum of Health Inequities.

Autoren: Abbas AA Dlova N Higgins CA

Quelle: The Journal of investigative dermatology [J Invest Dermatol] 2025 Dec; Vol. 145 (12), pp. 2973-2980. Date of Electronic Publication: 2025 Aug 08.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1747 (Electronic) Linking ISSN: 0022202X NLM ISO Abbreviation: J Invest Dermatol Subsets: MEDLINE

MeSH-Schlagworte: Skin Pigmentation*/physiology , Melanocytes*/physiology , Healthcare Disparities*/statistics & numerical data , Skin Diseases*/diagnosis , Skin Diseases*/therapy , Health Status Disparities*, Humans ; Skin/cytology ; Skin/pathology ; Melanins/metabolism

Effectiveness of double-layer artificial dermis repair material combined with autologous skin patch in repairing deep skin and soft tissue defects: a retrospective study.

Autoren: Xu Y Liu Y Cao P et al.

Quelle: The Journal of dermatological treatment [J Dermatolog Treat] 2025 Dec; Vol. 36 (1), pp. 2541970. Date of Electronic Publication: 2025 Aug 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE

MeSH-Schlagworte: Skin Transplantation*/methods , Skin Transplantation*/adverse effects , Skin, Artificial* , Soft Tissue Injuries*/surgery, Humans ; Retrospective Studies ; Male ; Female ; Adult ; Middle Aged ; Treatment Outcome ; Transplantation, Autologous/adverse effects ; Wound Healing ; Young Adult ; Skin/injuries ; Skin/pathology ; Cicatrix/etiology ; Cicatrix/prevention & control

Advances in 3D Printed Microneedles as a Prototype for Skin Targeted Therapeutics in Personalized Dermal Pharmaceuticals.

Autoren: Uddin MJ Baig MS Gholap AD et al.

Quelle: AAPS PharmSciTech [AAPS PharmSciTech] 2025 Dec 05; Vol. 27 (1), pp. 49. Date of Electronic Publication: 2025 Dec 05.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 100960111 Publication Model: Electronic Cited Medium: Internet ISSN: 1530-9932 (Electronic) Linking ISSN: 15309932 NLM ISO Abbreviation: AAPS PharmSciTech Subsets: MEDLINE

MeSH-Schlagworte: Printing, Three-Dimensional* , Drug Delivery Systems*/methods , Drug Delivery Systems*/instrumentation , Needles* , Skin*/metabolism , Skin*/drug effects, Humans ; Administration, Cutaneous ; Precision Medicine/methods ; Skin Absorption ; Skin Diseases/drug therapy ; Animals ; Pharmaceutical Preparations/administration & dosage

Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors.

Autoren: Sabri AH Smith F Cater Z et al.

Quelle: Drug delivery [Drug Deliv] 2025 Dec; Vol. 32 (1), pp. 2527824. Date of Electronic Publication: 2025 Jul 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9417471 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0464 (Electronic) Linking ISSN: 10717544 NLM ISO Abbreviation: Drug Deliv Subsets: MEDLINE

MeSH-Schlagworte: Skin Neoplasms*/drug therapy , Skin Neoplasms*/metabolism , Drug Delivery Systems*/methods , Carcinoma, Basal Cell*/drug therapy , Carcinoma, Basal Cell*/metabolism , Aminoquinolines*/administration & dosage , Antineoplastic Agents*/administration & dosage, Animals ; Imiquimod ; Swine ; Needles ; Administration, Cutaneous ; Mice ; Skin/metabolism ; Skin/drug effects ; Skin Absorption ; Humans ; Cell Line, Tumor ; Microinjections

Ibrutinib-loaded lipid nanocarriers exhibit antitumor effect in a human ex vivo skin model of melanoma.

Autoren: Souto-Silva MV Rodrigues NS Albuquerque LFF et al.

Quelle: International journal of pharmaceutics [Int J Pharm] 2025 Nov 30; Vol. 685, pp. 126249. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

MeSH-Schlagworte: Melanoma*/drug therapy , Melanoma*/pathology , Melanoma*/metabolism , Skin Neoplasms*/drug therapy , Skin Neoplasms*/pathology , Skin Neoplasms*/metabolism , Drug Carriers*/chemistry , Drug Carriers*/administration & dosage , Antineoplastic Agents*/administration & dosage , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/pharmacokinetics , Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , Pyrazoles*/administration & dosage , Pyrazoles*/pharmacology , Pyrimidines*/administration & dosage , Pyrimidines*/pharmacology , Protein Kinase Inhibitors*/administration & dosage , Protein Kinase Inhibitors*/pharmacology, Humans ; Adenine/analogs & derivatives ; Piperidines/administration & dosage ; Cell Line, Tumor ; Lipids/chemistry ; Skin/metabolism ; Skin/drug effects ; Skin Absorption ; Reactive Oxygen Species/metabolism ; Cell Proliferation/drug effects ; Cell Survival/drug effects

Regulatory mechanisms of transforming growth factor-β in senescence of fibroblast associated with refractory skin diseases.

Autoren: Zheng Y Lei J Zhang A et al.

Quelle: Experimental gerontology [Exp Gerontol] 2025 Nov; Vol. 211, pp. 112900. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 0047061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6815 (Electronic) Linking ISSN: 05315565 NLM ISO Abbreviation: Exp Gerontol Subsets: MEDLINE

MeSH-Schlagworte: Fibroblasts*/metabolism , Fibroblasts*/pathology , Cellular Senescence*/physiology , Transforming Growth Factor beta*/metabolism , Transforming Growth Factor beta*/physiology , Skin Diseases*/metabolism , Skin Diseases*/pathology , Skin Aging*, Humans ; Signal Transduction ; Senescence-Associated Secretory Phenotype ; Skin/metabolism ; Skin/pathology ; Oxidative Stress ; Animals ; Extracellular Matrix/metabolism ; Reactive Oxygen Species/metabolism

Skin microbiome and skin aging: emerging strategies for manipulation.

Autoren: Wang Z Yuan F Zhong X et al.

Quelle: Microbiological research [Microbiol Res] 2025 Nov; Vol. 300, pp. 128285. Date of Electronic Publication: 2025 Jul 24.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: G. Fischer Country of Publication: Germany NLM ID: 9437794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0623 (Electronic) Linking ISSN: 09445013 NLM ISO Abbreviation: Microbiol Res Subsets: MEDLINE

MeSH-Schlagworte: Skin Aging*/radiation effects , Skin Aging*/physiology , Microbiota*/radiation effects , Microbiota*/physiology , Skin*/microbiology , Skin*/radiation effects, Humans ; Ultraviolet Rays/adverse effects ; Aging ; Animals ; Skin Microbiome

A deep learning-based dual-branch framework for automated skin lesion segmentation and classification via dermoscopic Images.

Autoren: Owida HA El-Fattah IA Abuowaida S et al.

Quelle: Scientific reports [Sci Rep] 2025 Oct 29; Vol. 15 (1), pp. 37823. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Deep Learning* , Dermoscopy*/methods , Image Processing, Computer-Assisted*/methods , Skin Neoplasms*/diagnostic imaging , Skin Neoplasms*/diagnosis , Image Interpretation, Computer-Assisted*/methods , Skin Diseases*/diagnostic imaging , Skin Diseases*/diagnosis, Humans ; Algorithms ; Skin/diagnostic imaging ; Skin/pathology

Bioengineered Skin from a Platelet-Derived Hydrogel Repairs Full Thickness Wounds in a Pre-Clinical Mouse Model.

Autoren: Rahman MM Arellano CL Banakh I et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 14; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Wound Healing* , Hydrogels*/chemistry , Blood Platelets*/chemistry , Blood Platelets*/metabolism , Tissue Engineering*/methods , Skin*/metabolism , Skin*/injuries, Animals ; Mice ; Skin Transplantation/methods ; Humans ; Disease Models, Animal ; Mice, Nude ; Tissue Scaffolds/chemistry ; Skin, Artificial

Clinical consequences of age-related skin barrier dysfunction: Part II. Approach to barrier dysfunction in the geriatric population.

Autoren: Sanders M Wahhab R Kokikian N et al.

Quelle: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2025 Oct; Vol. 93 (4), pp. 917-926. Date of Electronic Publication: 2024 Aug 30.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Mosby Country of Publication: United States NLM ID: 7907132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6787 (Electronic) Linking ISSN: 01909622 NLM ISO Abbreviation: J Am Acad Dermatol Subsets: MEDLINE

MeSH-Schlagworte: Skin Aging*/physiology , Skin Diseases*/physiopathology , Skin Diseases*/therapy , Aging*/physiology, Humans ; Aged ; Female ; Male ; Aged, 80 and over ; Skin/physiopathology ; Skin Physiological Phenomena

Polarity-induced intermolecular association of ceramide liposomes for enhanced skin delivery.

Autoren: Choi TH Shin M Yang H et al.

Quelle: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126360. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

MeSH-Schlagworte: Ceramides*/chemistry , Ceramides*/administration & dosage , Skin*/metabolism, Liposomes ; Skin Absorption/drug effects ; Animals ; Administration, Cutaneous ; Humans ; Oleic Acid/chemistry ; Oleic Acid/administration & dosage ; Permeability ; Drug Delivery Systems ; Female ; Lecithins/chemistry ; Skin Aging/drug effects

Network Pharmacology Approach to Explore the Skin-Lightening Compounds and Potential Mechanisms of Chinese Herbal Medicines.

Autoren: Liang Y Chen J Fu C et al.

Quelle: Journal of cosmetic dermatology [J Cosmet Dermatol] 2025 Dec; Vol. 24 (12), pp. e70562.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Science Country of Publication: England NLM ID: 101130964 Publication Model: Print Cited Medium: Internet ISSN: 1473-2165 (Electronic) Linking ISSN: 14732130 NLM ISO Abbreviation: J Cosmet Dermatol Subsets: MEDLINE

MeSH-Schlagworte: Drugs, Chinese Herbal*/pharmacology , Skin Lightening Preparations*/pharmacology , Skin Pigmentation*/drug effects, Humans ; Network Pharmacology ; Protein Interaction Maps/drug effects ; Skin/drug effects ; Skin/metabolism ; Skin/cytology ; Molecular Docking Simulation ; Signal Transduction/drug effects ; Keratinocytes/drug effects ; Medicine, Chinese Traditional ; NF-kappa B/metabolism

Grape Seed Extract NSPCC1 Counteracts Mouse Skin Aging via Modulating MAPK and AMPK Pathways.

Autoren: Zhang Z Xue Z Wang Y et al.

Quelle: Journal of food science [J Food Sci] 2025 Dec; Vol. 90 (12), pp. e70620.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley on behalf of the Institute of Food Technologists Country of Publication: United States NLM ID: 0014052 Publication Model: Print Cited Medium: Internet ISSN: 1750-3841 (Electronic) Linking ISSN: 00221147 NLM ISO Abbreviation: J Food Sci Subsets: MEDLINE

MeSH-Schlagworte: Skin Aging*/drug effects , Skin Aging*/radiation effects , Grape Seed Extract*/pharmacology , AMP-Activated Protein Kinases*/metabolism , AMP-Activated Protein Kinases*/genetics , MAP Kinase Signaling System*/drug effects, Animals ; Mice ; Skin/drug effects ; Skin/metabolism ; Skin/radiation effects ; Ultraviolet Rays/adverse effects ; Proanthocyanidins/pharmacology ; Antioxidants/pharmacology ; Male

Tannic acid prevents UVB-induced skin photoaging by regulating ferroptosis through NRF2/SLC7A11/GPX4 signaling.

Autoren: Chen Z Ye L Zhu L et al.

Quelle: Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2025 Dec; Vol. 273, pp. 113309. Date of Electronic Publication: 2025 Nov 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Sequoia Country of Publication: Switzerland NLM ID: 8804966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2682 (Electronic) Linking ISSN: 10111344 NLM ISO Abbreviation: J Photochem Photobiol B Subsets: MEDLINE

MeSH-Schlagworte: Ultraviolet Rays*/adverse effects , NF-E2-Related Factor 2*/metabolism , Skin Aging*/drug effects , Skin Aging*/radiation effects , Ferroptosis*/drug effects , Ferroptosis*/radiation effects , Tannins*/pharmacology , Tannins*/chemistry , Signal Transduction*/drug effects , Signal Transduction*/radiation effects , Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism, Animals ; Humans ; Mice ; Mice, Inbred BALB C ; Reactive Oxygen Species/metabolism ; Fibroblasts/metabolism ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Fibroblasts/radiation effects ; Oxidative Stress/drug effects ; Oxidative Stress/radiation effects ; Skin/radiation effects ; Skin/metabolism ; Skin/cytology ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Antioxidants ; Cell Line ; Polyphenols

Efficacy and safety of the combination therapy of CO 2 laser and thalidomide in cutaneous classic Kaposi's sarcoma.

Autoren: Li X Sharma Poudel R Cao C et al.

Quelle: The Journal of dermatological treatment [J Dermatolog Treat] 2025 Dec; Vol. 36 (1), pp. 2539290. Date of Electronic Publication: 2025 Jul 30.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE

MeSH-Schlagworte: Sarcoma, Kaposi*/therapy , Sarcoma, Kaposi*/pathology , Thalidomide*/administration & dosage , Thalidomide*/adverse effects , Lasers, Gas*/therapeutic use , Lasers, Gas*/adverse effects , Skin Neoplasms*/therapy , Skin Neoplasms*/pathology, Humans ; Middle Aged ; Male ; Female ; Prospective Studies ; Aged ; Treatment Outcome ; Combined Modality Therapy/adverse effects ; Combined Modality Therapy/methods ; Skin/pathology ; Skin/radiation effects ; Adult ; Administration, Oral ; Follow-Up Studies

Rubus caesius leaves and stems in antiaging skin care products: antityrosinase, anticollagenase, antimicrobial activity, and transdermal distribution of main phenolic acids.

Autoren: Hering A Nowak A Muzykiewicz-Szymańska A et al.

Quelle: Pharmaceutical biology [Pharm Biol] 2025 Dec; Vol. 63 (1), pp. 731-753. Date of Electronic Publication: 2025 Nov 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

MeSH-Schlagworte: Plant Extracts*/pharmacology , Plant Extracts*/isolation & purification , Plant Extracts*/administration & dosage , Plant Extracts*/pharmacokinetics , Hydroxybenzoates*/isolation & purification , Hydroxybenzoates*/pharmacology , Hydroxybenzoates*/administration & dosage , Hydroxybenzoates*/pharmacokinetics , Skin Aging*/drug effects , Anti-Infective Agents*/isolation & purification , Anti-Infective Agents*/pharmacology , Anti-Infective Agents*/administration & dosage, Plant Leaves ; Animals ; Monophenol Monooxygenase/antagonists & inhibitors ; Monophenol Monooxygenase/metabolism ; Skin/drug effects ; Skin/metabolism ; Skin/microbiology ; Swine ; Plant Stems ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Antioxidants/administration & dosage ; Skin Absorption ; Collagenases/metabolism ; Administration, Cutaneous ; Skin Care/methods ; Hydrogels ; Ethanol/chemistry

Anti-aging potential of  Monascus purpureus  pigments in skin care.

Autoren: Rungruang R Panichakul T Peasura N et al.

Quelle: Pharmaceutical biology [Pharm Biol] 2025 Dec; Vol. 63 (1), pp. 683-697. Date of Electronic Publication: 2025 Sep 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

MeSH-Schlagworte: Monascus*/chemistry , Monascus*/metabolism , Antioxidants*/pharmacology , Antioxidants*/isolation & purification , Pigments, Biological*/pharmacology , Pigments, Biological*/isolation & purification , Skin Aging*/drug effects , Skin Care*/methods, Humans ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Cell Survival/drug effects ; Cell Survival/physiology ; Wound Healing/drug effects ; Fermentation ; Oryza ; Cells, Cultured ; Elastin/metabolism ; Skin/drug effects ; Skin/metabolism ; Collagenases/metabolism ; Dose-Response Relationship, Drug

The effects of human volatiles produced by skin microbiota on Forcipomyia (Lasiohelea) taiwana host preference.

Autoren: Lu T Zhang Y Gou D et al.

Quelle: Pest management science [Pest Manag Sci] 2025 Dec; Vol. 81 (12), pp. 7815-7826. Date of Electronic Publication: 2025 Jul 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published for SCI by Wiley Country of Publication: England NLM ID: 100898744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4998 (Electronic) Linking ISSN: 1526498X NLM ISO Abbreviation: Pest Manag Sci Subsets: MEDLINE

MeSH-Schlagworte: Skin*/microbiology , Skin*/chemistry , Volatile Organic Compounds*/metabolism , Volatile Organic Compounds*/pharmacology , Microbiota* , Ceratopogonidae*/physiology , Ceratopogonidae*/drug effects , Insect Repellents*/pharmacology, Humans ; Animals ; Gas Chromatography-Mass Spectrometry ; Female ; Male ; Bacteria/metabolism ; Bacteria/isolation & purification ; Skin Microbiome

Collagen peptides derived from sea bass scales (Lateolabrax maculatus) relieve photoaging through MAPK, NF-κB and TGF-β signaling pathways and modulating gut microbiota composition.

Autoren: Liu D Ren Y Peng Y et al.

Quelle: Food research international (Ottawa, Ont.) [Food Res Int] 2025 Dec; Vol. 221 (Pt 4), pp. 117521. Date of Electronic Publication: 2025 Sep 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH-Schlagworte: Skin Aging*/drug effects , Skin Aging*/radiation effects , Bass* , Gastrointestinal Microbiome*/drug effects , Collagen*/pharmacology , Collagen*/chemistry , Transforming Growth Factor beta*/metabolism , Peptides*/pharmacology , Animal Scales*/chemistry, Animals ; NF-kappa B/metabolism ; Mice ; Signal Transduction/drug effects ; Ultraviolet Rays/adverse effects ; Skin/radiation effects ; Skin/drug effects ; Mice, Nude ; Mitogen-Activated Protein Kinases/metabolism

Keratinocytes: new perspectives in inflammatory skin diseases.

Autoren: Ye J Lai Y

Quelle: Trends in molecular medicine [Trends Mol Med] 2025 Dec; Vol. 31 (12), pp. 1103-1113. Date of Electronic Publication: 2025 Apr 16.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-499X (Electronic) Linking ISSN: 14714914 NLM ISO Abbreviation: Trends Mol Med Subsets: MEDLINE

MeSH-Schlagworte: Keratinocytes*/metabolism , Keratinocytes*/immunology , Keratinocytes*/pathology , Skin Diseases*/metabolism , Skin Diseases*/pathology , Skin Diseases*/etiology , Skin Diseases*/immunology , Inflammation*/pathology , Inflammation*/metabolism , Inflammation*/immunology, Humans ; Animals ; Skin/pathology ; Skin/immunology