Výsledky vyhľadávania - "Sittewelle M"

Regulation of lipoprotein processing by GPNMB in foamy macrophages: potential therapeutic targets for atherosclerosis.

Autori: Wang, Junqi Peng, Liming Wang, Huan a ďalší

Zdroj: Nature Communications; 11/14/2025, Vol. 16 Issue 1, p1-23, 23p

Predmety: ATHEROSCLEROSIS, MACROPHAGES, PROTEINS, DRUG target, TRANSCRIPTION factors, TRIGLYCERIDES, FOAM cells, LIPOPROTEINS

Nondisruptive inducible labeling of ER-membrane contact sites using the Lamin B receptor.

Autori: Downie, Laura Ferrandiz, Nuria Courthold, Elizabeth a ďalší

Zdroj: PLoS Biology; 7/10/2025, Vol. 23 Issue 7, p1-28, 28p

Predmety: CELL morphology, ORGANELLES, MICROSCOPY, DEEP learning, CELL membranes

Activation of platelet-derived growth factor receptors regulate connective tissue growth factor protein levels via the AKT pathway in malignant mesothelioma cells.

Autori: Suehiro, Tomoya Ahmad, Khoja Mouhand Hoang, Nguyen Truong Duc a ďalší

Zdroj: Journal of Biochemistry; Dec2024, Vol. 176 Issue 6, p460-471, 12p

Predmety: PLATELET-derived growth factor receptors, CONNECTIVE tissue growth factor, PROTEIN kinase B, PROTEIN expression, PROTEIN synthesis

Single-Cell RNA-Seq Analysis Links DNMT3B and PFKFB4 Transcriptional Profiles with Metastatic Traits in Hepatoblastoma.

Autori: Desterke, Christophe Francés, Raquel Monge, Claudia a ďalší

Zdroj: Biomolecules (2218-273X); Nov2024, Vol. 14 Issue 11, p1394, 15p

Predmety: BENIGN tumors, DNA methylation, LIVER cancer, CHILDHOOD cancer, HEPATOBLASTOMA

Leveraging Neural Crest-Derived Tumors to Identify NF1 Cancer Stem Cell Signatures.

Autori: Khan, Sajjad Alson, Donia Sun, Li a ďalší

Zdroj: Cancers; Nov2024, Vol. 16 Issue 21, p3639, 11p

Predmety: DRUG resistance in cancer cells, NEUROECTODERMAL tumors, NEUROFIBROMATOSIS 1, TUMOR markers, GENE expression profiling, STEM cells, MOLECULAR biology, DISEASE progression

Overexpression of TPD52L2 in HNSCC: prognostic significance and correlation with immune infiltrates.

Autori: Lu, Min Xia, Haoyu Xu, Jing a ďalší

Zdroj: BMC Oral Health; 10/7/2024, Vol. 24 Issue 1, p1-15, 15p

Predmety: SQUAMOUS cell carcinoma, PROTEINS, RESEARCH funding, RECEIVER operating characteristic curves, HEAD & neck cancer, POLYMERASE chain reaction, IMMUNE system, CELLULAR signal transduction, CELL motility, GENE expression, IMMUNOHISTOCHEMISTRY, MESSENGER RNA, BIOINFORMATICS, ONCOGENES, WESTERN immunoblotting, SURVIVAL analysis (Biometry), DISEASE progression, PROPORTIONAL hazards models, OVERALL survival

PRMT5 activates AKT via methylation to promote tumor metastasis.

Autori: Huang, Lei Zhang, Xiao-Ou Rozen, Esteban J. a ďalší

Zdroj: Nature Communications; 7/8/2022, Vol. 13 Issue 1, p1-16, 16p

Predmety: PROTEIN arginine methyltransferases, PROTEIN kinase B, METASTASIS, METHYLATION, CELL membranes, TRANSCRIPTION factors

ATG9A vesicles are a subtype of intracellular nanovesicle.

Autori: Fesenko, Mary Moore, Daniel J. Ewbank, Peyton a ďalší

Zdroj: Journal of Cell Science; Apr2025, Vol. 138 Issue 7, p1-15, 15p

Predmety: AUTOPHAGY, PROTEIN transport, BIOCHEMICAL variation, INTRACELLULAR membranes, MEMBRANE proteins

Suleiman-El-Hattab syndrome: a histone modification disorder caused by TASP1 deficiency.

Autori: Riedhammer, Korbinian M Burgemeister, Anna L Cantagrel, Vincent a ďalší

Zdroj: Human Molecular Genetics; 9/15/2022, Vol. 31 Issue 18, p3083-3094, 12p

Canonical and Non-Canonical Roles of Human DNA Polymerase η.

Autori: Bedaiwi, Salma Usmani, Anam Carty, Michael P.

Zdroj: Genes; Oct2024, Vol. 15 Issue 10, p1-22, 22p, 3 Diagrams

Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis.

Autori: Rashidieh, Behnam Shohayeb, Belal Bain, Amanda Louise a ďalší

Zdroj: PLoS Genetics; 10/28/2021, Vol. 17 Issue 10, p1-31, 31p

Predmety: PI3K/AKT pathway, LABORATORY mice, EMBRYOLOGY, SYMPTOMS, NEURAL development, PLURIPOTENT stem cells

Small ubiquitin-related modifier 2 affects the intracellular survival of Brucella abortus 2308 by regulating activation of the NF-κB pathway.

Autori: Wang, Yueli Xi, Jing Wu, Peng a ďalší

Zdroj: Innate Immunity; Jan2021, Vol. 27 Issue 1, p81-88, 8p

Predmety: BRUCELLA abortus, SMALL ubiquitin-related modifier proteins, GRAM-negative bacteria, PATHOGENIC bacteria, ANIMAL diseases

Mechanistic divergences of endocytic clathrin-coated vesicle formation in mammals, yeasts and plants.

Autori: Johnson, Alexander

Zdroj: Journal of Cell Science; Aug2024, Vol. 137 Issue 16, p1-13, 13p

The PI3K/Akt Pathway and Glucose Metabolism: A Dangerous Liaison in Cancer.

Autori: Fontana, Fabrizio Giannitti, Gaia Marchesi, Sara a ďalší

Zdroj: International Journal of Biological Sciences; 2024, Vol. 20 Issue 9, p3113-3125, 13p

Identification of genomic determinants contributing to cytokine release in immunotherapies and human diseases.

Autori: Shao, Lipei Pelayo, Alejandra Shi, Rongye a ďalší

Zdroj: Journal of Translational Medicine; 7/28/2022, Vol. 20 Issue 1, p1-12, 12p

Weighted gene co-expression network analysis and whole genome sequencing identify potential lung cancer biomarkers.

Autori: Abudereheman, Mireguli Zhengjun Lian Ainitu, Baidurula

Zdroj: Frontiers in Oncology; 2024, p1-11, 11p

Predmety: WHOLE genome sequencing, GENE ontology, GENE regulatory networks, TUMOR markers, LUNG cancer, CONTACT tracing, GENE expression

Revamping the corneal permeability and antiglaucoma therapeutic potential of brinzolamide using transniosomes: optimization, in vitro and preclinical evaluation.

Autori: Patil, Rushikesh K Srivastava, Vaibhavi Bhawale, Rohit a ďalší

Zdroj: Nanomedicine; May2024, Vol. 19 Issue 11, p947-964, 18p

Structural basis for RAD18 regulation by MAGEA4 and its implications for RING ubiquitin ligase binding by MAGE family proteins.

Autori: Griffith-Jones, Simonne Álvarez, Lucía Mukhopadhyay, Urbi a ďalší

Zdroj: EMBO Journal; Apr2024, Vol. 43 Issue 7, p1273-1300, 28p

Predmety: UBIQUITIN ligases, UBIQUITIN, DNA synthesis, PEPTIDES, PROTEINS, DNA repair

Expression of Constitutive Fusion of Ubiquitin to PCNA Restores the Level of Immunoglobulin A/T Mutations During Somatic Hypermutation in the Ramos Cell Line.

Autori: Lerner, Leticia K. Bonte, Dorine Le Guillou, Morwenna a ďalší

Zdroj: Frontiers in Immunology; 4/1/2022, Vol. 13, p1-14, 14p

Predmety: CELL lines, PROLIFERATING cell nuclear antigen, IMMUNOGLOBULIN genes, UBIQUITIN, IMMUNOGLOBULIN class switching, CYTIDINE deaminase, SOMATIC mutation

RNase H activities counteract a toxic effect of Polymerase η in cells replicating with depleted dNTP pools.

Autori: Meroni, Alice Nava, Giulia Maria Bianco, Eliana a ďalší

Zdroj: Nucleic Acids Research; 5/21/2019, Vol. 47 Issue 9, p4612-4623, 12p