Výsledky vyhľadávania - "Single-Blind Method"

Physiological effects of nasal high flow therapy during exercise in patients with chronic obstructive pulmonary disease: A crossover randomised controlled trial.

Autori: Bonnevie T Gravier FE Smondack P a ďalší

Zdroj: Pulmonology [Pulmonology] 2025 Dec 31; Vol. 31 (1), pp. 2424649. Date of Electronic Publication: 2024 Nov 20.

Spôsob vydávania: Journal Article; Randomized Controlled Trial

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101723786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-0437 (Electronic) Linking ISSN: 25310429 NLM ISO Abbreviation: Pulmonology Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pulmonary Disease, Chronic Obstructive*/physiopathology , Pulmonary Disease, Chronic Obstructive*/therapy , Oxygen Inhalation Therapy*/methods , Exercise*/physiology, Humans ; Cross-Over Studies ; Male ; Female ; Middle Aged ; Single-Blind Method ; Aged ; Dyspnea/physiopathology ; Dyspnea/therapy ; Dyspnea/etiology ; Exercise Test/methods ; Respiratory Muscles/physiopathology ; Exercise Tolerance/physiology ; Tidal Volume

Comparison of M-TAPA and EOIB to TAP Block in Laparoscopic Cholecystectomy: A Single-Blind Randomized Controlled Trial.

Autori: Matsuura H Terada Y Tanaka N a ďalší

Zdroj: The Tokai journal of experimental and clinical medicine [Tokai J Exp Clin Med] 2025 Dec 20; Vol. 50 (3), pp. 75-80. Date of Electronic Publication: 2025 Dec 20.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Comparative Study; Clinical Trial

Informácie o časopise: Publisher: Tokai University School Of Medicine Country of Publication: Japan NLM ID: 7704186 Publication Model: Electronic Cited Medium: Internet ISSN: 2185-2243 (Electronic) Linking ISSN: 03850005 NLM ISO Abbreviation: Tokai J Exp Clin Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholecystectomy, Laparoscopic*/methods , Cholecystectomy, Laparoscopic*/adverse effects , Nerve Block*/methods , Pain, Postoperative*/prevention & control, Humans ; Female ; Male ; Middle Aged ; Adult ; Single-Blind Method ; Treatment Outcome ; Aged ; Prospective Studies ; Pain Measurement ; Abdominal Muscles/innervation ; Pain Management/methods ; Time Factors

Far infrared therapy improves vascular function by enhancing endothelial function and decreasing arterial stiffness via cytoprotective pathways.

Autori: Bagabir H Mohammad OA Lang CC a ďalší

Zdroj: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 16; Vol. 241, pp. 438-446. Date of Electronic Publication: 2025 Sep 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Vascular Stiffness*/radiation effects , Infrared Rays*/therapeutic use , Endothelium, Vascular*/radiation effects , Endothelium, Vascular*/metabolism , Endothelium, Vascular*/physiology, Humans ; Male ; Adult ; Female ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type III/metabolism ; Pilot Projects ; Single-Blind Method ; HSP70 Heat-Shock Proteins/genetics ; Middle Aged ; Leukocytes, Mononuclear/radiation effects ; Leukocytes, Mononuclear/metabolism ; Gene Expression Regulation/radiation effects ; Cytoprotection/radiation effects

Effectiveness of a Remote Intervention Program for Self-Management Behaviors in Adolescents and Young Adults With Inflammatory Bowel Disease Based on the Self-Determination Theory: Randomized Controlled Trial Across 2 Centers.

Autori: Zhu Y Chen Y Hu J a ďalší

Zdroj: Journal of medical Internet research [J Med Internet Res] 2025 Dec 05; Vol. 27, pp. e79370. Date of Electronic Publication: 2025 Dec 05.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Multicenter Study

Informácie o časopise: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 100959882 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-8871 (Electronic) Linking ISSN: 14388871 NLM ISO Abbreviation: J Med Internet Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Inflammatory Bowel Diseases*/therapy , Inflammatory Bowel Diseases*/psychology , Self-Management* , Personal Autonomy*, Humans ; Adolescent ; Male ; Female ; Young Adult ; Single-Blind Method ; Social Support ; China ; Quality of Life

Comparative effects of French Contrast Method vs. Complex Training on explosive power and its endurance in youth badminton athletes.

Autori: Huang R Gao Y Yang K a ďalší

Zdroj: PloS one [PLoS One] 2025 Dec 05; Vol. 20 (12), pp. e0338383. Date of Electronic Publication: 2025 Dec 05 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Comparative Study

Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Výrazy zo slovníka MeSH: Racquet Sports*/physiology , Physical Endurance*/physiology , Muscle Strength*/physiology , Athletes* , Athletic Performance*/physiology , Physical Conditioning, Human*/methods, Humans ; Male ; Adolescent ; Single-Blind Method

Acupuncture (Jin's Three-Needle) versus sham acupuncture in treating mild-to-moderate depression: Study protocol for randomized clinical trial.

Autori: Wen H Wang J Zhang K a ďalší

Zdroj: PloS one [PLoS One] 2025 Dec 05; Vol. 20 (12), pp. e0338341. Date of Electronic Publication: 2025 Dec 05 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Clinical Trial Protocol

Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Výrazy zo slovníka MeSH: Acupuncture Therapy*/methods , Depression*/therapy, Humans ; Adult ; Female ; Single-Blind Method ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome ; Randomized Controlled Trials as Topic ; Needles ; Young Adult

Efficacy of FiberMore, an AI-Based mHealth Intervention to Increase Dietary Fiber Intake Among Type 2 Diabetes Patients: Protocol for a Pilot Randomized Controlled Trial.

Autori: Sze WT Waki K Lane D a ďalší

Zdroj: JMIR research protocols [JMIR Res Protoc] 2025 Dec 04; Vol. 14, pp. e78019. Date of Electronic Publication: 2025 Dec 04.

Spôsob vydávania: Journal Article; Clinical Trial Protocol

Informácie o časopise: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101599504 Publication Model: Electronic Cited Medium: Internet ISSN: 1929-0748 (Electronic) Linking ISSN: 19290748 NLM ISO Abbreviation: JMIR Res Protoc Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diabetes Mellitus, Type 2*/diet therapy , Dietary Fiber*/administration & dosage , Artificial Intelligence*, Humans ; Pilot Projects ; Telemedicine ; Female ; Male ; Japan ; Single-Blind Method ; Glycated Hemoglobin/analysis ; Middle Aged ; Randomized Controlled Trials as Topic ; Aged

Effectiveness of Different Methods of Interdental Hygiene in Daily Practice Among Young Adults: Protocol for a Randomized, Single-Blind Controlled Trial.

Autori: Carrouel F Lan R Saliasi I a ďalší

Zdroj: JMIR research protocols [JMIR Res Protoc] 2025 Dec 04; Vol. 14, pp. e85154. Date of Electronic Publication: 2025 Dec 04.

Spôsob vydávania: Journal Article; Clinical Trial Protocol

Informácie o časopise: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101599504 Publication Model: Electronic Cited Medium: Internet ISSN: 1929-0748 (Electronic) Linking ISSN: 19290748 NLM ISO Abbreviation: JMIR Res Protoc Subsets: MEDLINE

Výrazy zo slovníka MeSH: Oral Hygiene*/methods, Humans ; Adult ; Single-Blind Method ; Young Adult ; Adolescent ; Male ; Female ; Periodontal Index ; Toothbrushing/methods ; Randomized Controlled Trials as Topic ; Periodontal Diseases/prevention & control ; Gingivitis/prevention & control

Effect of the index of consciousness 2 on intraoperative opioid dosage in ovarian cancer patients receiving neoadjuvant chemotherapy: a study protocol for a randomised controlled trial.

Autori: Ding Y Halisa P Xing L a ďalší

Zdroj: BMJ open [BMJ Open] 2025 Dec 03; Vol. 15 (12), pp. e099607. Date of Electronic Publication: 2025 Dec 03.

Spôsob vydávania: Journal Article; Clinical Trial Protocol

Informácie o časopise: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/surgery , Analgesics, Opioid*/administration & dosage , Neoadjuvant Therapy* , Consciousness Monitors* , Monitoring, Intraoperative*/methods, Humans ; Female ; Prospective Studies ; Single-Blind Method ; Randomized Controlled Trials as Topic ; Pain, Postoperative/drug therapy ; Remifentanil/administration & dosage ; Adult ; Cytoreduction Surgical Procedures ; Middle Aged ; Anesthesia, General

"Laser assisted gingival melanin depigmentation using diode 450 nm; ablative vs. non-ablative techniques: randomized clinical trial".

Autori: Altayeb W Luk K Arnabat-Dominguez J a ďalší

Zdroj: Lasers in medical science [Lasers Med Sci] 2025 Dec 03; Vol. 40 (1), pp. 509. Date of Electronic Publication: 2025 Dec 03.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Comparative Study

Informácie o časopise: Publisher: Springer Country of Publication: England NLM ID: 8611515 Publication Model: Electronic Cited Medium: Internet ISSN: 1435-604X (Electronic) Linking ISSN: 02688921 NLM ISO Abbreviation: Lasers Med Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lasers, Semiconductor*/therapeutic use , Melanins*/metabolism , Gingival Diseases*/surgery, Humans ; Female ; Adult ; Male ; Single-Blind Method ; Middle Aged ; Treatment Outcome ; Young Adult

The effects of mindfulness training on emotion and sleep quality in patients with colorectal cancer.

Autori: Shi L Xin S Li DN a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Dec 03; Vol. 15 (1), pp. 43064. Date of Electronic Publication: 2025 Dec 03.

Spôsob vydávania: Journal Article; Randomized Controlled Trial

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Colorectal Neoplasms*/psychology , Colorectal Neoplasms*/therapy , Mindfulness*/methods , Sleep Quality* , Emotions*/physiology, Humans ; Male ; Female ; Middle Aged ; Aged ; Single-Blind Method ; Adult ; Sleep ; Quality of Life

Steerable versus Conventional flexible and navigable suction ureteral access sheath (FANS) flexible Ureteroscopy for Lower Pole stones Treatment: study protocol for a multicentre, randomised superiority trial (SCULPT trial).

Autori: Yuen SKK Steffi Liu S Gauhar V a ďalší

Zdroj: BMJ open [BMJ Open] 2025 Dec 02; Vol. 15 (12), pp. e103866. Date of Electronic Publication: 2025 Dec 02.

Spôsob vydávania: Journal Article; Clinical Trial Protocol

Informácie o časopise: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ureteroscopy*/methods , Ureteroscopy*/instrumentation , Kidney Calculi*/surgery , Ureteroscopes*, Humans ; Adult ; Prospective Studies ; Middle Aged ; Single-Blind Method ; Multicenter Studies as Topic ; Aged ; Young Adult ; Adolescent ; Female ; Male ; China ; Suction/instrumentation ; Equivalence Trials as Topic ; Randomized Controlled Trials as Topic

Efficacy and safety of autologous adipose-derived stem cells in subjects with moderate to severe atopic dermatitis: a multicenter, randomized, single-blind, placebo-controlled, phase 2 trial.

Autori: Seok J Kim SY Lee WG a ďalší

Zdroj: Stem cell research & therapy [Stem Cell Res Ther] 2025 Dec 02; Vol. 16 (1), pp. 671. Date of Electronic Publication: 2025 Dec 02.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

Výrazy zo slovníka MeSH: Dermatitis, Atopic*/therapy , Dermatitis, Atopic*/pathology , Adipose Tissue*/cytology , Mesenchymal Stem Cell Transplantation*/methods , Mesenchymal Stem Cells*/cytology , Mesenchymal Stem Cells*/metabolism, Humans ; Male ; Female ; Adult ; Single-Blind Method ; Middle Aged ; Transplantation, Autologous ; Young Adult ; Adolescent ; Treatment Outcome

Individualized Perioperative Blood Pressure Management in Patients Undergoing Major Abdominal Surgery: The IMPROVE-multi Randomized Clinical Trial.

Autori: Saugel B Meidert AS Brunkhorst FM a ďalší

Korporácia: Saugel B Meidert AS Brunkhorst FM a ďalší

Zdroj: JAMA [JAMA] 2025 Dec 02; Vol. 334 (21), pp. 1893-1904.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Multicenter Study; Comment

Informácie o časopise: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE

Výrazy zo slovníka MeSH: Abdomen*/surgery , Antihypertensive Agents*/therapeutic use , Hypotension*/diagnosis , Hypotension*/drug therapy , Hypotension*/prevention & control , Perioperative Care*/methods , Postoperative Complications*/epidemiology , Postoperative Complications*/etiology , Postoperative Complications*/prevention & control , Intraoperative Complications*/diagnosis , Intraoperative Complications*/drug therapy , Intraoperative Complications*/prevention & control , Monitoring, Intraoperative*/methods, Aged ; Female ; Humans ; Male ; Middle Aged ; Acute Kidney Injury/epidemiology ; Acute Kidney Injury/etiology ; Acute Kidney Injury/prevention & control ; Blood Pressure ; Elective Surgical Procedures/adverse effects ; Heart Arrest/epidemiology ; Heart Arrest/etiology ; Heart Arrest/prevention & control ; Single-Blind Method ; Incidence ; Blood Pressure Determination/methods ; Hospital Mortality

Comparison of safety, salivary flow rate, and pH with different mouthrinse formulations in addition to toothbrushing vs toothbrushing only: Results from a 2-week phase 4 randomized controlled clinical trial.

Autori: Milleman K Bosma ML Saito A a ďalší

Zdroj: Journal of the American Dental Association (1939) [J Am Dent Assoc] 2025 Dec; Vol. 156 (12), pp. 991-1000.e3.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Comparative Study; Clinical Trial, Phase IV

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 7503060 Publication Model: Print Cited Medium: Internet ISSN: 1943-4723 (Electronic) Linking ISSN: 00028177 NLM ISO Abbreviation: J Am Dent Assoc Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mouthwashes*/adverse effects , Mouthwashes*/chemistry , Mouthwashes*/therapeutic use , Toothbrushing*/methods , Saliva*/metabolism , Saliva*/drug effects , Oils, Volatile*/adverse effects , Oils, Volatile*/therapeutic use, Humans ; Female ; Male ; Hydrogen-Ion Concentration ; Adult ; Middle Aged ; Single-Blind Method ; Secretory Rate/drug effects ; Young Adult

Efficacy of core muscle strengthening training around the knee compared to oral nonsteroidal anti-inflammatory drugs in early-stage knee osteoarthritis patients: protocol for a randomized controlled trial.

Autori: Wei C Wang X Xiong Y a ďalší

Zdroj: Trials [Trials] 2025 Dec 01; Vol. 26 (1), pp. 555. Date of Electronic Publication: 2025 Dec 01.

Spôsob vydávania: Journal Article; Clinical Trial Protocol

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoarthritis, Knee*/therapy , Osteoarthritis, Knee*/physiopathology , Osteoarthritis, Knee*/rehabilitation , Osteoarthritis, Knee*/diagnosis , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects , Anti-Inflammatory Agents, Non-Steroidal*/therapeutic use , Resistance Training*/methods , Knee Joint*/physiopathology, Humans ; Single-Blind Method ; Randomized Controlled Trials as Topic ; Treatment Outcome ; Administration, Oral ; Equivalence Trials as Topic ; Pain Measurement ; Muscle Strength ; Quality of Life ; Time Factors ; Middle Aged ; Male ; Female

Preliminary Outcomes of a Culturally Adapted Fear of Recurrence Therapy (FORT) for Turkish Breast Cancer Survivors: A Randomized Controlled Trial.

Autori: Eyrenci A Ertuna L Bahçivan O

Zdroj: Psycho-oncology [Psychooncology] 2025 Dec; Vol. 34 (12), pp. e70345.

Spôsob vydávania: Journal Article; Randomized Controlled Trial

Informácie o časopise: Publisher: Wiley Country of Publication: England NLM ID: 9214524 Publication Model: Print Cited Medium: Internet ISSN: 1099-1611 (Electronic) Linking ISSN: 10579249 NLM ISO Abbreviation: Psychooncology Subsets: MEDLINE

Výrazy zo slovníka MeSH: Breast Neoplasms*/psychology , Breast Neoplasms*/therapy , Cancer Survivors*/psychology , Neoplasm Recurrence, Local*/psychology , Cognitive Behavioral Therapy*/methods , Fear*/psychology, Humans ; Female ; Middle Aged ; Turkey ; Quality of Life/psychology ; Single-Blind Method ; Adult ; Adaptation, Psychological ; Anxiety/therapy ; Anxiety/psychology ; Depression/psychology ; Depression/therapy ; Aged ; Self Efficacy

Massage and exercise increase body awareness in healthy adults: A single blinded randomized controlled trial.

Autori: Danner U Avian A Mittermaier C

Zdroj: Journal of bodywork and movement therapies [J Bodyw Mov Ther] 2025 Dec; Vol. 45, pp. 508-515. Date of Electronic Publication: 2025 Sep 10.

Spôsob vydávania: Journal Article; Randomized Controlled Trial

Informácie o časopise: Publisher: Churchill Livingstone Country of Publication: United States NLM ID: 9700068 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-9283 (Electronic) Linking ISSN: 13608592 NLM ISO Abbreviation: J Bodyw Mov Ther Subsets: MEDLINE

Výrazy zo slovníka MeSH: Massage*/methods , Massage*/psychology , Body Image*/psychology , Awareness*/physiology , Exercise*/psychology , Exercise*/physiology , Exercise Therapy*/methods, Humans ; Female ; Adult ; Middle Aged ; Male ; Self Concept ; Single-Blind Method ; Affect ; Surveys and Questionnaires

The effect of a ketone monoester drink on blood glucose and substrate oxidation in adults with metabolic syndrome and matched controls.

Autori: Graybeal AJ Aultman RS Brandner CF a ďalší

Zdroj: Physiological reports [Physiol Rep] 2025 Dec; Vol. 13 (23), pp. e70676.

Spôsob vydávania: Journal Article; Randomized Controlled Trial

Informácie o časopise: Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM ID: 101607800 Publication Model: Print Cited Medium: Internet ISSN: 2051-817X (Electronic) Linking ISSN: 2051817X NLM ISO Abbreviation: Physiol Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Metabolic Syndrome*/blood , Metabolic Syndrome*/metabolism , Ketones*/administration & dosage , Blood Glucose*/metabolism , Blood Glucose*/drug effects , Esters*/administration & dosage, Humans ; Male ; Adult ; Female ; Oxidation-Reduction/drug effects ; Middle Aged ; Single-Blind Method ; Cross-Over Studies ; Energy Metabolism/drug effects ; Beverages

Noncontact Midair Ultrasonic Neuromodulation of the Median and Ulnar Nerves Induces Frequency-Specific Parasympathetic and Cortical Network Responses in Healthy Adults.

Autori: Pryer TA Mathew J Khwaounjoo P a ďalší

Zdroj: Neuromodulation : journal of the International Neuromodulation Society [Neuromodulation] 2025 Dec; Vol. 28 (8), pp. 1354-1365. Date of Electronic Publication: 2025 Nov 25.

Spôsob vydávania: Journal Article; Randomized Controlled Trial

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 9804159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-1403 (Electronic) Linking ISSN: 10947159 NLM ISO Abbreviation: Neuromodulation Subsets: MEDLINE

Výrazy zo slovníka MeSH: Median Nerve*/physiology , Ulnar Nerve*/physiology , Cerebral Cortex*/physiology , Parasympathetic Nervous System*/physiology , Ultrasonic Therapy*/methods , Nerve Net*/physiology, Humans ; Male ; Female ; Adult ; Cross-Over Studies ; Single-Blind Method ; Young Adult ; Heart Rate/physiology ; Electroencephalography ; Electrocardiography ; Healthy Volunteers