Výsledky vyhľadávania - "Schizophrenia"

Saliva Based Clozapine Therapeutic Drug Monitoring: A Systematic Review.

Autori: Rademaker T Chu R Hasan S a ďalší

Zdroj: Pharmacology research & perspectives [Pharmacol Res Perspect] 2025 Oct; Vol. 13 (5), pp. e70165.

Spôsob vydávania: Journal Article; Systematic Review

Informácie o časopise: Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 101626369 Publication Model: Print Cited Medium: Internet ISSN: 2052-1707 (Electronic) Linking ISSN: 20521707 NLM ISO Abbreviation: Pharmacol Res Perspect Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antipsychotic Agents*/pharmacokinetics , Antipsychotic Agents*/therapeutic use , Clozapine*/pharmacokinetics , Clozapine*/analysis , Clozapine*/therapeutic use , Drug Monitoring*/methods , Saliva*/chemistry , Schizophrenia, Treatment-Resistant*/drug therapy, Humans ; Schizophrenia/drug therapy

Increased Ribosome Biogenesis and Increased Oxidative Stress in Blood Leukocytes of Patients With Catatonic Schizophrenia Compared With Paranoid Schizophrenia.

Autori: Ershova ES Veiko NN Agafonova ON a ďalší

Zdroj: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2025 Aug 30; Vol. 30 (8), pp. 39426.

Spôsob vydávania: Journal Article; Comparative Study

Informácie o časopise: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101612996 Publication Model: Print Cited Medium: Internet ISSN: 2768-6698 (Electronic) Linking ISSN: 27686698 NLM ISO Abbreviation: Front Biosci (Landmark Ed) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Oxidative Stress* , Leukocytes*/metabolism , Ribosomes*/metabolism , Ribosomes*/genetics , Schizophrenia, Paranoid*/blood , Schizophrenia, Paranoid*/genetics , Schizophrenia, Paranoid*/metabolism , Catatonia*/genetics , Catatonia*/blood , Catatonia*/metabolism, Humans ; Male ; Female ; Adult ; Middle Aged ; DNA, Ribosomal/genetics ; Schizophrenia ; Case-Control Studies

THE EFFECTS OF THIRD-GENERATION ANTIPSYCHOTIC DRUGS ON THE PSYCHOSOCIAL FUNCTIONING OF PATIENTS WITH SCHIZOPHRENIA.

Autori: Spikina A Savelyev A Odinets A a ďalší

Zdroj: Psychiatria Danubina [Psychiatr Danub] 2025 Sep; Vol. 37 (Suppl 1), pp. 278-283.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Facultas Universitatis [i.e. Facultas Medica Universitatis] Studiorum Zagrabiensis in cooperation with WHO Collaborating Centre for Research and Training in Mental Health--KBC Zagreb, on behalf of the Danube Symposion of Psychiatry Country of Publication: Croatia NLM ID: 9424753 Publication Model: Print Cited Medium: Print ISSN: 0353-5053 (Print) Linking ISSN: 03535053 NLM ISO Abbreviation: Psychiatr Danub Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antipsychotic Agents*/therapeutic use , Antipsychotic Agents*/adverse effects , Antipsychotic Agents*/administration & dosage , Antipsychotic Agents*/pharmacology , Psychosocial Functioning* , Schizophrenia, Paranoid*/drug therapy , Schizophrenia, Paranoid*/psychology , Schizophrenic Psychology* , Piperazines*/therapeutic use , Piperazines*/adverse effects, Humans ; Male ; Female ; Adult ; Young Adult ; Cognitive Dysfunction ; Schizophrenia/drug therapy

The Safety of 12-Weekly Monitoring of Neutrophil Count in Long-Term Clozapine Patients.

Autori: Taylor D Gee S Helthuis M a ďalší

Zdroj: Acta psychiatrica Scandinavica [Acta Psychiatr Scand] 2025 Sep; Vol. 152 (3), pp. 187-192. Date of Electronic Publication: 2025 May 03.

Spôsob vydávania: Journal Article; Observational Study

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 0370364 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0447 (Electronic) Linking ISSN: 0001690X NLM ISO Abbreviation: Acta Psychiatr Scand Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antipsychotic Agents*/adverse effects , Antipsychotic Agents*/therapeutic use , Antipsychotic Agents*/administration & dosage , Clozapine*/adverse effects , Clozapine*/administration & dosage , Clozapine*/therapeutic use , Neutropenia*/chemically induced , Neutropenia*/epidemiology , Neutrophils* , Schizophrenia*/drug therapy, Adult ; Female ; Humans ; Male ; Middle Aged ; Agranulocytosis/chemically induced ; Agranulocytosis/epidemiology ; COVID-19/epidemiology ; Drug Monitoring/methods ; Leukocyte Count ; Retrospective Studies ; Schizophrenia, Treatment-Resistant/drug therapy ; Schizophrenia, Treatment-Resistant/blood ; United Kingdom/epidemiology

Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study.

Autori: Seppälä J Grasa E Alonso-Solis A a ďalší

Korporácia: Seppälä J Grasa E Alonso-Solis A a ďalší

Zdroj: JMIR human factors [JMIR Hum Factors] 2025 May 15; Vol. 12, pp. e67659. Date of Electronic Publication: 2025 May 15.

Spôsob vydávania: Journal Article; Multicenter Study

Informácie o časopise: Publisher: JMIR Publications Inc Country of Publication: Canada NLM ID: 101666561 Publication Model: Electronic Cited Medium: Internet ISSN: 2292-9495 (Electronic) Linking ISSN: 22929495 NLM ISO Abbreviation: JMIR Hum Factors Subsets: MEDLINE

Výrazy zo slovníka MeSH: Schizophrenia, Treatment-Resistant*/therapy , Mobile Applications*, Humans ; Female ; Male ; Adult ; Prospective Studies ; Telemedicine ; Middle Aged ; Quality of Life ; Treatment Outcome ; Feasibility Studies ; Spain ; Israel ; Hungary ; Schizophrenia/therapy

Competence and confidence of health care professionals in using clozapine: a qualitative systematic review and thematic synthesis.

Autori: Secchi A Whiskey E Nair S a ďalší

Zdroj: Acta neuropsychiatrica [Acta Neuropsychiatr] 2025 Jun 30; Vol. 37, pp. e73. Date of Electronic Publication: 2025 Jun 30.

Spôsob vydávania: Journal Article; Systematic Review; Review

Informácie o časopise: Publisher: Cambridge University Press Country of Publication: England NLM ID: 9612501 Publication Model: Electronic Cited Medium: Internet ISSN: 1601-5215 (Electronic) Linking ISSN: 09242708 NLM ISO Abbreviation: Acta Neuropsychiatr Subsets: MEDLINE

Výrazy zo slovníka MeSH: Clozapine*/therapeutic use , Clozapine*/adverse effects , Antipsychotic Agents*/therapeutic use , Antipsychotic Agents*/adverse effects , Health Personnel*/psychology , Clinical Competence* , Schizophrenia, Treatment-Resistant*/drug therapy , Health Knowledge, Attitudes, Practice* , Attitude of Health Personnel*, Humans ; Schizophrenia/drug therapy

A Case of Clozapine Induced Mania-Like Symptoms in the Treatment of Schizophrenia.

Autori: Sze AH Pola AS Smith AG a ďalší

Zdroj: Psychopharmacology bulletin [Psychopharmacol Bull] 2025 Apr 08; Vol. 55 (3), pp. 56-59.

Spôsob vydávania: Case Reports; Journal Article

Informácie o časopise: Publisher: MedWorks Media Country of Publication: United States NLM ID: 0101123 Publication Model: Print Cited Medium: Internet ISSN: 2472-2448 (Electronic) Linking ISSN: 00485764 NLM ISO Abbreviation: Psychopharmacol Bull Subsets: MEDLINE

Výrazy zo slovníka MeSH: Clozapine*/adverse effects , Clozapine*/therapeutic use , Antipsychotic Agents*/adverse effects , Antipsychotic Agents*/therapeutic use , Mania*/chemically induced , Schizophrenia*/drug therapy, Humans ; Male ; Middle Aged ; Schizophrenia, Treatment-Resistant/drug therapy

Lights and shadows of clozapine on the immune system in schizophrenia: a narrative literature review.

Autori: Liu J Zhao W Wang Y

Zdroj: Metabolic brain disease [Metab Brain Dis] 2025 Feb 15; Vol. 40 (2), pp. 128. Date of Electronic Publication: 2025 Feb 15.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Springer Country of Publication: United States NLM ID: 8610370 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7365 (Electronic) Linking ISSN: 08857490 NLM ISO Abbreviation: Metab Brain Dis Subsets: MEDLINE

Výrazy zo slovníka MeSH: Clozapine*/therapeutic use , Clozapine*/adverse effects , Clozapine*/pharmacology , Antipsychotic Agents*/therapeutic use , Antipsychotic Agents*/adverse effects , Antipsychotic Agents*/pharmacology , Schizophrenia*/drug therapy , Schizophrenia*/immunology , Immune System*/drug effects, Humans ; Schizophrenia, Treatment-Resistant/drug therapy ; Schizophrenia, Treatment-Resistant/immunology

Formal Thought Disorders and Neurocognition in Treatment-Resistant Schizophrenia: Trouble du cours de la pensée et neurocognition dans la schizophrénie réfractaire.

Autori: Alarabi M Burton L Powell V a ďalší

Zdroj: Canadian journal of psychiatry. Revue canadienne de psychiatrie [Can J Psychiatry] 2025 Mar; Vol. 70 (3), pp. 229-239. Date of Electronic Publication: 2024 Nov 04.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Sage Country of Publication: United States NLM ID: 7904187 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1497-0015 (Electronic) Linking ISSN: 07067437 NLM ISO Abbreviation: Can J Psychiatry Subsets: MEDLINE

Výrazy zo slovníka MeSH: Schizophrenia, Treatment-Resistant*/physiopathology , Schizophrenia, Treatment-Resistant*/complications , Cognitive Dysfunction*/physiopathology , Cognitive Dysfunction*/etiology , Thinking*/physiology, Humans ; Male ; Female ; Adult ; Retrospective Studies ; Middle Aged ; Schizophrenia

Glutamate, GABA and NAA in treatment-resistant schizophrenia: A systematic review of the effect of clozapine and group differences between clozapine-responders and non-responders.

Autori: Kristensen MWP Biuk B Nielsen J a ďalší

Zdroj: Behavioural brain research [Behav Brain Res] 2025 Feb 28; Vol. 479, pp. 115338. Date of Electronic Publication: 2024 Nov 19.

Spôsob vydávania: Systematic Review; Journal Article

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Clozapine*/pharmacology , gamma-Aminobutyric Acid*/metabolism , Glutamic Acid*/metabolism , Aspartic Acid*/analogs & derivatives , Aspartic Acid*/metabolism , Antipsychotic Agents*/pharmacology , Schizophrenia, Treatment-Resistant*/drug therapy , Schizophrenia, Treatment-Resistant*/metabolism, Humans ; Brain/metabolism ; Brain/drug effects ; Brain/diagnostic imaging ; Schizophrenia/drug therapy ; Schizophrenia/metabolism

Shared polygenic susceptibility to treatment response in severe affective and psychotic disorders: Evidence from GWAS data sets.

Autori: Facal F Costas J

Zdroj: Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2025 Jan 10; Vol. 136, pp. 111183. Date of Electronic Publication: 2024 Oct 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 8211617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4216 (Electronic) Linking ISSN: 02785846 NLM ISO Abbreviation: Prog Neuropsychopharmacol Biol Psychiatry Subsets: MEDLINE

Výrazy zo slovníka MeSH: Multifactorial Inheritance*/genetics , Psychotic Disorders*/genetics , Psychotic Disorders*/drug therapy , Genetic Predisposition to Disease*/genetics , Antidepressive Agents*/therapeutic use , Bipolar Disorder*/genetics , Bipolar Disorder*/drug therapy , Depressive Disorder, Major*/genetics , Depressive Disorder, Major*/drug therapy , Schizophrenia, Treatment-Resistant*/genetics , Schizophrenia, Treatment-Resistant*/drug therapy, Humans ; Genome-Wide Association Study ; Antipsychotic Agents/therapeutic use ; Treatment Outcome ; Schizophrenia/genetics ; Schizophrenia/drug therapy

Immunophenotyping schizophrenia subtypes stratified by antipsychotic response.

Autori: Li Y Ong JWX See YM a ďalší

Zdroj: Brain, behavior, and immunity [Brain Behav Immun] 2025 Jan; Vol. 123, pp. 656-671. Date of Electronic Publication: 2024 Oct 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antipsychotic Agents*/therapeutic use , Antipsychotic Agents*/pharmacology , Immunophenotyping*/methods , Schizophrenia*/drug therapy , Schizophrenia*/immunology , Clozapine*/therapeutic use , Clozapine*/pharmacology, Humans ; Adult ; Male ; Female ; Middle Aged ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/immunology ; Schizophrenia, Treatment-Resistant/drug therapy ; Flow Cytometry/methods

Treatment-resistant schizophrenia with 22q11.2 deletion and additional genetic defects.

Autori: Furukawa S Arafuka S Kato H a ďalší

Zdroj: Neuropsychopharmacology reports [Neuropsychopharmacol Rep] 2024 Dec; Vol. 44 (4), pp. 847-851. Date of Electronic Publication: 2024 Aug 27.

Spôsob vydávania: Case Reports; Journal Article

Informácie o časopise: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101719700 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2574-173X (Electronic) Linking ISSN: 2574173X NLM ISO Abbreviation: Neuropsychopharmacol Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: DiGeorge Syndrome*/genetics , Schizophrenia, Treatment-Resistant*/genetics , Schizophrenia, Treatment-Resistant*/diagnosis, Humans ; Female ; Middle Aged ; Intellectual Disability/genetics ; Schizophrenia/genetics ; Schizophrenia/diagnosis

Prevalence of treatment-resistant schizophrenia among people with early psychosis and its clinical and demographic correlates.

Autori: Detanac M Williams C Dragovic M a ďalší

Zdroj: The Australian and New Zealand journal of psychiatry [Aust N Z J Psychiatry] 2024 Dec; Vol. 58 (12), pp. 1080-1089. Date of Electronic Publication: 2024 Aug 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Sage Country of Publication: England NLM ID: 0111052 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1614 (Electronic) Linking ISSN: 00048674 NLM ISO Abbreviation: Aust N Z J Psychiatry Subsets: MEDLINE

Výrazy zo slovníka MeSH: Psychotic Disorders*/epidemiology , Psychotic Disorders*/therapy , Psychotic Disorders*/drug therapy , Schizophrenia, Treatment-Resistant*/epidemiology, Humans ; Male ; Female ; Prevalence ; Adult ; Young Adult ; Western Australia/epidemiology ; Adolescent ; Schizophrenia/epidemiology ; Schizophrenia/therapy ; Antipsychotic Agents/therapeutic use

Factors associated with cognitive dysfunction in treatment-responsive and -resistant schizophrenia: A pilot cross-sectional study.

Autori: Suzuki Y Watanabe K Kanno-Nozaki K a ďalší

Zdroj: Journal of psychiatric research [J Psychiatr Res] 2024 Oct; Vol. 178, pp. 228-235. Date of Electronic Publication: 2024 Aug 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 0376331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1379 (Electronic) Linking ISSN: 00223956 NLM ISO Abbreviation: J Psychiatr Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antipsychotic Agents*/pharmacology , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/physiopathology , Clozapine*/pharmacology , Clozapine*/analogs & derivatives , Schizophrenia, Treatment-Resistant*/drug therapy , Schizophrenia, Treatment-Resistant*/blood, Humans ; Male ; Female ; Cross-Sectional Studies ; Pilot Projects ; Adult ; Middle Aged ; Homovanillic Acid/blood ; Schizophrenia/drug therapy ; Schizophrenia/blood ; Schizophrenia/complications ; Schizophrenia/physiopathology ; Psychiatric Status Rating Scales

Deep brain stimulation of Hippocampus in Treatment-resistant Schizophrenia (DBS-HITS): protocol for a crossover randomized controlled trial.

Autori: Lu C Zhai Z Zhuo K a ďalší

Zdroj: BMC psychiatry [BMC Psychiatry] 2024 Nov 25; Vol. 24 (1), pp. 847. Date of Electronic Publication: 2024 Nov 25.

Spôsob vydávania: Clinical Trial Protocol; Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 100968559 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-244X (Electronic) Linking ISSN: 1471244X NLM ISO Abbreviation: BMC Psychiatry Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cross-Over Studies* , Deep Brain Stimulation*/methods , Hippocampus*/diagnostic imaging , Hippocampus*/physiopathology , Schizophrenia, Treatment-Resistant*/therapy, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Electroencephalography/methods ; Schizophrenia/therapy ; Schizophrenia/physiopathology ; Randomized Controlled Trials as Topic

Dysregulated oxidative stress and lactate levels in treatment-resistant schizophrenia.

Autori: Fang Y Zhang T Xu K a ďalší

Zdroj: Brain, behavior, and immunity [Brain Behav Immun] 2025 Nov; Vol. 130, pp. 106111. Date of Electronic Publication: 2025 Sep 15.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Oxidative Stress*/physiology , Lactic Acid*/metabolism , Lactic Acid*/blood , Schizophrenia, Treatment-Resistant*/metabolism , Schizophrenia, Treatment-Resistant*/physiopathology , Schizophrenia*/metabolism, Animals ; Mice ; Humans ; Male ; Female ; Astrocytes/metabolism ; Extracellular Vesicles/metabolism ; Adult ; Proteomics/methods ; Middle Aged ; Antipsychotic Agents ; Disease Models, Animal ; Neurons/metabolism ; Mice, Inbred C57BL ; Prepulse Inhibition/physiology

Therapeutic Effect of Evenamide, a Glutamate Inhibitor, in Patients With Treatment-Resistant Schizophrenia (TRS): Final, 1-Year Results From a Phase 2, Open-Label, Rater-Blinded, Randomized, International Clinical Trial.

Autori: Anand R Turolla A Chinellato G a ďalší

Zdroj: The international journal of neuropsychopharmacology [Int J Neuropsychopharmacol] 2024 Dec 28; Vol. 28 (1).

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 9815893 Publication Model: Print Cited Medium: Internet ISSN: 1469-5111 (Electronic) Linking ISSN: 14611457 NLM ISO Abbreviation: Int J Neuropsychopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antipsychotic Agents*/pharmacology , Antipsychotic Agents*/administration & dosage , Antipsychotic Agents*/therapeutic use , Schizophrenia, Treatment-Resistant*/drug therapy, Humans ; Male ; Adult ; Female ; Treatment Outcome ; Middle Aged ; Psychiatric Status Rating Scales ; Young Adult ; Pilot Projects ; Schizophrenia/drug therapy ; Single-Blind Method

Clozapine rechallenge following myocarditis: a systematic review of rechallenge cases.

Autori: McMahon L Giudice M Wagner E a ďalší

Zdroj: CNS spectrums [CNS Spectr] 2024 Dec; Vol. 29 (6), pp. 585-592. Date of Electronic Publication: 2024 Dec 20.

Spôsob vydávania: Systematic Review; Journal Article

Informácie o časopise: Publisher: Cambridge University Press Country of Publication: United States NLM ID: 9702877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-8529 (Print) Linking ISSN: 10928529 NLM ISO Abbreviation: CNS Spectr Subsets: MEDLINE

Výrazy zo slovníka MeSH: Clozapine*/adverse effects , Clozapine*/administration & dosage , Clozapine*/therapeutic use , Myocarditis*/chemically induced , Antipsychotic Agents*/adverse effects , Antipsychotic Agents*/administration & dosage , Antipsychotic Agents*/therapeutic use , Schizophrenia, Treatment-Resistant*/drug therapy, Humans ; Schizophrenia/drug therapy

The factors associated with clozapine polypharmacy for schizophrenia patients discharged from a large public psychiatric hospital in Taiwan, 2006-2021.

Autori: Shih YJ Lin CH Chou LS

Zdroj: Medicine [Medicine (Baltimore)] 2024 Dec 20; Vol. 103 (51), pp. e40897.

Spôsob vydávania: Journal Article; Observational Study

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antipsychotic Agents*/therapeutic use , Antipsychotic Agents*/administration & dosage , Clozapine*/therapeutic use , Hospitals, Psychiatric*/statistics & numerical data , Patient Discharge*/statistics & numerical data , Polypharmacy* , Schizophrenia*/drug therapy, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Age Factors ; Hospitals, Public ; Length of Stay/statistics & numerical data ; Retrospective Studies ; Schizophrenia, Treatment-Resistant/drug therapy ; Sex Factors ; Taiwan