Výsledky vyhledávání - "Sarcoplasmic Reticulum Calcium-Transporting ATPases metabolism"

Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart

Autoři: Monika M Gladka Arwa Kohela Anne E de Leeuw a další

Přispěvatelé: Monika M Gladka Arwa Kohela Anne E de Leeuw a další

Zdroj: Cardiovasc Res
Cardiovascular Research

Témata: Male, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Calcium/metabolism, Cells, Inbred C57BL, alpha Subunit/metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Mice, Sarcoplasmic Reticulum/metabolism, Journal Article, MicroRNAs/metabolism, Animals, Myocytes, Cardiac, Gene Regulatory Networks, Calcium Signaling, Phosphorylation, Cells, Cultured, Zinc Finger E-box Binding Homeobox 2, Myocytes, Cultured, Ventricular Remodeling, Animal, Calcineurin, Calcium-Binding Proteins, Hypoxia-Inducible Factor 1, alpha Subunit, Myocardial Contraction, Cell Hypoxia, Zinc Finger E-box Binding Homeobox 2/genetics, Mice, Inbred C57BL, Disease Models, Animal, Sarcoplasmic Reticulum, MicroRNAs, Cardiac/metabolism, Disease Models, Calcineurin/metabolism, Original Article, Calcium, Hypoxia-Inducible Factor 1

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39308239
https://dspace.library.uu.nl/handle/1874/458978

Restoring Atrial T-Tubules Augments Systolic Ca Upon Recovery From Heart Failure

Autoři: Jessica L. Caldwell Jessica D. Clarke Charlotte E.R. Smith a další

Zdroj: Circ Res
Caldwell, J L, Clarke, J D, Smith, C E R, Pinali, C, Quinn, C J, Pearman, C M, Adomaviciene, A, Radcliffe, E J, Watkins, A E, Horn, M A, Bode, E F, Madders, G W P, Eisner, M, Eisner, D A, Trafford, A W & Dibb, K M 2024, 'Restoring Atrial T-Tubules Augments Systolic Ca Upon Recovery From Heart Failure', Circulation research, vol. 135, no. 7, pp. 739-754. https://doi.org/10.1161/CIRCRESAHA.124.324601

Témata: 0301 basic medicine, Calcium/metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Heart Failure/metabolism, Systole, Cells, Heart Atria/metabolism, Mitochondria, Heart, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Sarcoplasmic Reticulum/metabolism, Animals, Myocytes, Cardiac, Heart Atria, Calcium Signaling, Cells, Cultured, Original Research, Heart Failure, Myocytes, Cultured, Sheep, Heart/metabolism, Ryanodine Receptor Calcium Release Channel, Myocytes, Cardiac/metabolism, Recovery of Function, Mitochondria, Heart/metabolism, Mitochondria, Rats, 3. Good health, Sarcoplasmic Reticulum, Cardiac/metabolism, Calcium, Female, Sprague-Dawley, Ryanodine Receptor Calcium Release Channel/metabolism

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39140440

Effects of 8 Weeks of Moderate‐ or High‐Volume Strength Training on Sarcoplasmic Reticulum Ca2+ Handling in Elite Female and Male Rowers

Autoři: Oscar Mazza Joachim Nielsen Jonas Mathiesen a další

Zdroj: Scand J Med Sci Sports
Mazza, O, Nielsen, J, Mathiesen, J, Højme, D, Lundby, C, Hostrup, M, Thomassen, M, Plomgaard, P, Gejl, K D & Ørtenblad, N 2025, ' Effects of 8 Weeks of Moderate-or High-Volume Strength Training on Sarcoplasmic Reticulum Ca 2+ Handling in Elite Female and Male Rowers ', Scandinavian Journal of Medicine and Science in Sports, vol. 35, no. 1, e70017 . https://doi.org/10.1111/sms.70017

Témata: Male, Adult, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Calcium/metabolism, sex difference, Resistance Training/methods, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Young Adult, Sarcoplasmic Reticulum/metabolism, Skeletal/physiology, Myosin Heavy Chains/metabolism, strength training, Humans, Muscle Strength, Muscle, Skeletal, Water Sports, Water Sports/physiology, Myosin Heavy Chains, Ca release, Ca uptake, muscle plasticity, Resistance Training, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Muscle Strength/physiology, Muscle, Original Article, Female, Calcium, Ryanodine Receptor Calcium Release Channel/metabolism

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39831408
https://curis.ku.dk/ws/files/422459323/Scandinavian_Med_Sci_Sports_2025_Mazza_Effects_of_8_Weeks_of_Moderate_or_High_Volume_Strength_Training_on.pdf

Dietary nitrate increases submaximal SERCA activity and ADP transfer to mitochondria in slow-twitch muscle of female mice

Autoři: Heather L. Petrick Stuart Brownell Bayley Vachon a další

Přispěvatelé: Heather L. Petrick Stuart Brownell Bayley Vachon a další

Zdroj: American Journal of Physiology-Endocrinology and Metabolism. 323:E171-E184

Témata: 0301 basic medicine, mice, Calcium/metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Adenosine Triphosphate/metabolism, Skeletal/metabolism, Nitrates/metabolism, Fatigue/metabolism, Muscle Fibers, Slow-Twitch/metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Muscle Fibers, Slow-Twitch/metabolism, Mice, 03 medical and health sciences, Adenosine Triphosphate, contractile function, nitrate, SERCA, Mitochondria/metabolism, Animals, Muscle, Skeletal, Fatigue, Adenosine Diphosphate/metabolism, 0303 health sciences, Muscle, Skeletal/metabolism, Nitrates, calcium homeostasis, Mitochondria, mitochondria, Adenosine Diphosphate, Muscle Fibers, Slow-Twitch, Muscle, Calcium, Female, Muscle Contraction/physiology, Muscle Contraction

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35732003
https://cris.maastrichtuniversity.nl/en/publications/6b7d76cf-2990-4a84-bb81-814b574e1d3b
https://doi.org/10.1152/ajpendo.00371.2021
https://acuresearchbank.acu.edu.au/item/8y905/dietary-nitrate-increases-submaximal-serca-activity-and-adp-transfer-to-mitochondria-in-slow-twitch-muscle-of-female-mice
https://biblio.vub.ac.be/vubir/dietary-nitrate-increases-submaximal-serca-activity-and-adp-transfer-to-mitochondria-in-slowtwitch-muscle-of-female-mice(406a234b-fc99-4097-8177-8abd785cdb7f).html

Th17-associated cytokines IL-17 and IL-23 in inflamed skin of Darier disease patients as potential therapeutic targets

Autoři: Monika Ettinger Teresa Burner Anshu Sharma a další

Zdroj: Nat Commun
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Nature communications, vol. 14, no. 1, pp. 7470

Témata: Science, Interleukin-17, Humans, Th17 Cells, Darier Disease/genetics, Darier Disease/metabolism, Darier Disease/pathology, Interleukin-17/genetics, Interleukin-17/metabolism, Interleukin-23/metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Skin/pathology, Th17 Cells/metabolism, Darier Disease, Interleukin-23, Article, 3. Good health, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Skin

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37978298
https://doaj.org/article/8eec8722afcf4e4cb83878c6585c3720
https://serval.unil.ch/resource/serval:BIB_D062CF696E69.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_D062CF696E69
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_D062CF696E698

Calcium Fluxes in Work-Related Muscle Disorder: Implications from a Rat Model: Implications from a Rat Model

Autoři: J. Hadrevi M. F. Barbe N. Ørtenblad a další

Zdroj: Biomed Res Int
Hadrevi, J, Barbe, M F, Ørtenblad, N, Frandsen, U, Boyle, E, Lazar, S, Sjøgaard, G & Søgaard, K 2019, ' Calcium Fluxes in Work-Related Muscle Disorder : Implications from a Rat Model ', BioMed Research International, vol. 2019, 5040818 . https://doi.org/10.1155/2019/5040818, https://doi.org/10.1155/2019/5040818

Témata: Cytosol/metabolism, 0301 basic medicine, Calcium/metabolism, Mitochondrial Proteins/metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Neurologi, Skeletal/metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Mitochondrial Proteins, Rats, Sprague-Dawley, 03 medical and health sciences, Cytosol, 0302 clinical medicine, Calcium-Binding Proteins/metabolism, Sarcoplasmic Reticulum/metabolism, Muscular Diseases, Animals, Muscle, Skeletal, Excitation Contraction Coupling/physiology, Excitation Contraction Coupling, Muscle, Skeletal/metabolism, Animal, Calcium-Binding Proteins, Ryanodine Receptor Calcium Release Channel, Myalgia, Myalgia/metabolism, Rats, Disease Models, Animal, Sarcoplasmic Reticulum, Neurology, Disease Models, Muscle, Calcium, Female, Sprague-Dawley, Muscular Diseases/metabolism, Ryanodine Receptor Calcium Release Channel/metabolism, Muscle Contraction/physiology, Research Article, Muscle Contraction

Popis souboru: text/xhtml; application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/31662979
https://portal.findresearcher.sdu.dk/da/publications/calcium-fluxes-in-work-related-muscle-disorder-implications-from-
https://downloads.hindawi.com/journals/bmri/2019/5040818.pdf
http://downloads.hindawi.com/journals/bmri/2019/5040818.pdf
https://www.ncbi.nlm.nih.gov/pubmed/31662979
https://pubmed.ncbi.nlm.nih.gov/31662979/
https://findresearcher.sdu.dk:8443/ws/files/155675071/5040818.pdf
https://findresearcher.sdu.dk:8443/ws/files/155675071/5040818.pdf
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-165114

Drug Discovery Using Evolutionary Similarities in Chemical Binding to Inhibit Patient-Derived Hepatocellular Carcinoma

Přispěvatelé: Jin Hong Lim Keunwan Park Kyung Hwa Choi a další

Témata: Calcium / metabolism, Carcinoma, Hepatocellular* / drug therapy, Hepatocellular* / genetics, Hepatocellular* / metabolism, Drug Discovery, Endoplasmic Reticulum / metabolism, Humans, Liver Neoplasms* / drug therapy, Liver Neoplasms* / genetics, Liver Neoplasms* / metabolism, Sarcoplasmic Reticulum / metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases / genetics, Sarcoplasmic Reticulum Calcium-Transporting ATPases / metabolism, Thapsigargin / pharmacology, cancer stem cells, candidate 19, candidate 23, endoplasmic reticulum stress, patient-derived anti-cancer drug-resistant hepatocellular carcinoma, sarcoplasmic/endoplasmic reticulum calcium ATPase, thapsigargin

Popis souboru: application/pdf

Relation: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; J01133; https://ir.ymlib.yonsei.ac.kr/handle/22282913/191676; T202204422

Dostupnost: https://ir.ymlib.yonsei.ac.kr/handle/22282913/191676
https://doi.org/10.3390/ijms23147971

The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses

Autoři: Jingxian Duan Jorge Navarro-Dorado Jill H. Clark a další

Přispěvatelé: Jingxian Duan Jorge Navarro-Dorado Jill H. Clark a další

Zdroj: Nat Commun
Docta Complutense
instname
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Duan, J, Navarro-Dorado, J, Clark, J H, Kinnear, N P, Meinke, P, Schirmer, E C & Evans, A M 2019, ' The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses ', vol. 10, no. 1, 2299 . https://doi.org/10.1038/s41467-019-10055-w

Témata: Cytosol/metabolism, Male, 0301 basic medicine, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, 24 Ciencias de la Vida, Nuclear Envelope, Science, Primary Cell Culture, Cell Proliferation/physiology, Calcium Signaling/physiology, Article, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Rats, Sprague-Dawley, 03 medical and health sciences, Cytosol, Sarcoplasmic Reticulum/metabolism, Animals, Muscle Cells/physiology, Calcium Signaling, Muscle, Skeletal, Cells, Cultured, Nuclear Envelope/metabolism, Cell Proliferation, Muscle Cells, 0303 health sciences, Cell Membrane/metabolism, Cell Membrane, Ryanodine Receptor Calcium Release Channel, Rats, Sarcoplasmic Reticulum, Muscle, Skeletal/cytology, Ciencias Biomédicas, Sprague-Dawley, Ryanodine Receptor Calcium Release Channel/metabolism, Muscle Contraction/physiology, Muscle Contraction

Popis souboru: application/pdf

Přístupová URL adresa: https://www.nature.com/articles/s41467-019-10055-w.pdf
https://pubmed.ncbi.nlm.nih.gov/31127110
https://hdl.handle.net/20.500.14352/115653
https://doaj.org/article/1588c52787ed490bbdbdcbdbcc560603
https://www.nature.com/articles/s41467-019-10055-w.pdf
http://www-nature-com-443.webvpn.bjmu.tsg211.com/articles/s41467-019-10055-w.pdf
https://www.pure.ed.ac.uk/ws/files/121720800/s41467_019_10055_w.pdf
https://www.research.ed.ac.uk/portal/en/publications/the-cellwide-web-coordinates-cellular-processes-by-directing-sitespecific-ca2-flux-across-cytoplasmic-nanocourses(397b07ce-1d01-4ad1-bea8-0960dea5e7c8).html
http://www-nature-com-443.webvpn.bjmu.tsg211.com/articles/s41467-019-10055-w
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534574/
https://www.pure.ed.ac.uk/ws/files/96504396/s41467_019_10055_w.pdf
https://hdl.handle.net/20.500.11820/8a58d842-5d8d-4072-8653-fda568693427

SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells

Autoři: Philippe, Réginald Antigny, Fabrice Buscaglia, Paul a další

Přispěvatelé: Philippe, Réginald Antigny, Fabrice Buscaglia, Paul a další

Zdroj: Biochimica et Biophysica Acta, Vol. 1853, No 5 (2015) pp. 892-903

Témata: 0301 basic medicine, MESH: Cystic Fibrosis / pathology, Cystic Fibrosis, [SDV]Life Sciences [q-bio], MESH: Calcium / metabolism, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, [SDV.BC.IC] Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], MESH: Epithelial Cells / drug effects, Endoplasmic Reticulum, MESH: Benzodioxoles / pharmacology, Adenosine Triphosphate, PMCA, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], Homeostasis, MESH: Cystic Fibrosis Transmembrane Conductance Regulator, 0303 health sciences, MESH: Endoplasmic Reticulum / metabolism, MESH: Adenosine Triphosphate / pharmacology, MESH: Plasma Membrane Calcium-Transporting ATPases / metabolism, Mitochondria, MESH: Homeostasis* / drug effects, MESH: Protein Binding / drug effects, Protein Binding, MESH: Aminopyridines / pharmacology, MESH: Bronchi / pathology, Bronchi, MESH: Epithelial Cells / enzymology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, MESH: Epithelial Cells / pathology, Cystic fibrosis, F508del-CFTR, Cell Line, Sarcoplasmic Reticulum Calcium-Transporting ATPases, MESH: Sarcoplasmic Reticulum Calcium-Transporting ATPases / metabolism, Plasma Membrane Calcium-Transporting ATPases, 03 medical and health sciences, SERCA, Humans, Benzodioxoles, ddc:612, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Molecular Biology, MESH: Humans, MESH: Endoplasmic Reticulum / drug effects, MESH: Mitochondria / drug effects, Calcium signaling, Epithelial Cells, Cell Biology, MESH: Cell Line, MESH: Mitochondria / metabolism, Calcium

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/25661196
https://europepmc.org/abstract/MED/25661196
https://pubmed.ncbi.nlm.nih.gov/25661196/
https://hal.archives-ouvertes.fr/hal-01134260
http://www.ncbi.nlm.nih.gov/pubmed/25661196
https://archive-ouverte.unige.ch/unige:75584
https://www.sciencedirect.com/science/article/pii/S0167488915000191
https://archive-ouverte.unige.ch/unige:75584
https://archive-ouverte.unige.ch/unige:75584
https://doi.org/10.1016/j.bbamcr.2015.01.010

Homer2 Protein Regulates Plasma Membrane Ca2+-ATPase-mediated Ca2+ Signaling in Mouse Parotid Gland Acinar Cells

Autoři: Hae Jo Dong Min Shin Shmuel Muallem a další

Přispěvatelé: Hae Jo Dong Min Shin Shmuel Muallem a další

Zdroj: Journal of Biological Chemistry. 289:24971-24979

Témata: 0301 basic medicine, Carrier Proteins/genetics, Parotid Gland/metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Knockout, Molecular Sequence Data, Sequence Homology, Binding Sites/genetics, Parotid Gland/cytology, Mice, 03 medical and health sciences, Homer Scaffolding Proteins, Cell Signaling, Acinar Cells/metabolism, Animals, Humans, Parotid Gland, Amino Acid Sequence, Calcium Signaling, Calcium Transport, Inositol 1,4,5-Trisphosphate Receptors/metabolism, Microscopy, 0303 health sciences, Proline-rich Motif, Blotting, Calcium/metabolism, Homer Proteins, Plasma Membrane Calcium-Transporting ATPases/genetics, Protein-Protein Interaction, Amino Acid, HEK293 Cells, Carrier Proteins/metabolism, Confocal, Plasma Membrane Calcium-Transporting ATPases/metabolism, Scaffold Protein, Calcium ATPase, Western, Plasma Membrane Ca2+-ATPase, Protein Binding

Popis souboru: 24971~24979

Přístupová URL adresa: http://www.jbc.org/content/289/36/24971.full.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155665
https://www.sciencedirect.com/science/article/pii/S0021925820316525
https://ir.ymlib.yonsei.ac.kr/handle/22282913/99704
https://europepmc.org/article/MED/25049230
https://www.jbc.org/content/289/36/24971.full
https://yonsei.pure.elsevier.com/en/publications/homer2-protein-regulates-plasma-membrane-ca-sup2sup-atpase-mediat

Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis

Autoři: Su, Qiaozhu Baker, Chris Christian, Patricia a další

Zdroj: American Journal of Physiology-Endocrinology and Metabolism. 306:E1264-E1273

Témata: Liver/metabolism, Male, 0301 basic medicine, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Lipoproteins, Knockout, Blotting, Western, Primary Cell Culture, Fructose/pharmacology, Mitochondria, Liver, PPAR alpha/genetics, Fructose, Lipoproteins, VLDL, Inbred C57BL, Real-Time Polymerase Chain Reaction, Fluorescence, Dyslipidemias/etiology, Mice, 03 medical and health sciences, Animals, Homeostasis, PPAR alpha, Apolipoproteins B, Dyslipidemias, Hypertriglyceridemia, Mice, Knockout, Microscopy, 0303 health sciences, Blotting, Fatty Liver/metabolism, Signal Transduction/physiology, Homeostasis/physiology, VLDL/metabolism, Endoplasmic Reticulum Stress/physiology, Endoplasmic Reticulum Stress, Apolipoproteins B/metabolism, Mitochondria, Rats, Hypertriglyceridemia/blood, Fatty Liver, Mice, Inbred C57BL, Microscopy, Fluorescence, Hepatocytes, Hepatocytes/drug effects, Western, Ultracentrifugation

Přístupová URL adresa: https://europepmc.org/articles/pmc4280162
https://pubmed.ncbi.nlm.nih.gov/24735884
https://www.physiology.org/doi/10.1152/ajpendo.00438.2013
https://pubmed.ncbi.nlm.nih.gov/24735884/
https://www.physiology.org/doi/pdf/10.1152/ajpendo.00438.2013
http://ajpendo.physiology.org/content/306/11/E1264
https://nebraska.pure.elsevier.com/en/publications/hepatic-mitochondrial-and-er-stress-induced-by-defective-ppar%CE%B1-si
http://www.ncbi.nlm.nih.gov/pmc/articles/4280162/

Emerging role of epigenetics and miRNA in diabetic cardiomyopathy

Autoři: Asrih, Mohamed Steffens, Sabine

Zdroj: Cardiovascular Pathology, Vol. 22, No 2 (2013) pp. 117-125

Témata: 0301 basic medicine, 0303 health sciences, 616.8, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Diabetic Cardiomyopathies/genetics/pathology/physiopathology, Diabetic Cardiomyopathies, Dyslipidemias/complications/metabolism, Histones/metabolism, Models, Cardiovascular, Protein Kinase C/metabolism, DNA Methylation, ddc:616.8, Epigenesis, Genetic, Sarcoplasmic Reticulum Calcium-Transporting ATPases, 3. Good health, Histones, MicroRNAs/genetics, MicroRNAs, Oxidative Stress, 03 medical and health sciences, Hyperglycemia, Humans, Hyperglycemia/complications/metabolism, Protein Kinase C, Dyslipidemias

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/22951386
https://pubmed.ncbi.nlm.nih.gov/22951386/
https://europepmc.org/article/MED/22951386
https://www.ncbi.nlm.nih.gov/pubmed/22951386
https://archive-ouverte.unige.ch/unige:96810
http://www.sciencedirect.com/science/article/pii/S1054880712000944
https://www.sciencedirect.com/science/article/pii/S1054880712000944
https://archive-ouverte.unige.ch/unige:96810
https://doi.org/10.1016/j.carpath.2012.07.004
https://archive-ouverte.unige.ch/unige:96810

Artificial mirtron-mediated gene knockdown: Functional DMPK silencing in mammalian cells

Autoři: Seow, Yiqi Sibley, Christopher R Wood, Matthew J A

Zdroj: Seow, Y, Sibley, C R & Wood, M J A 2012, ' Artificial mirtron-mediated gene knockdown : Functional DMPK silencing in mammalian cells ', RNA, vol. 18, no. 7, pp. 1328-37 . https://doi.org/10.1261/rna.030601.111

Témata: Ribonuclease III, 0301 basic medicine, mice, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, gene knockdown techniques, Transcription, Genetic, introns, Protein-Serine-Threonine Kinases/genetics, Molecular Sequence Data, Karyopherins, Protein Serine-Threonine Kinases, Myotonin-Protein Kinase, Cell Line, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Myoblasts, alternative splicing, gene silencing, Mice, 03 medical and health sciences, Molecular sequence data, Ribonuclease III/metabolism, Animals, Humans, Gene Silencing, humans, 0303 health sciences, Base Sequence, Myoblasts/metabolism, cell line, base sequence, Introns, animals, Alternative Splicing, Gene Knockdown Techniques, Karyopherins/metabolism, RNA Interference, genetic, transcription

Popis souboru: application/pdf

Přístupová URL adresa: http://rnajournal.cshlp.org/content/18/7/1328.full.pdf
https://pubmed.ncbi.nlm.nih.gov/22647847
https://www.dpag.ox.ac.uk/publications/334765
http://europepmc.org/articles/PMC3383964
https://pubmed.ncbi.nlm.nih.gov/22647847/
https://www.neuroscience.ox.ac.uk/publications/334765
https://thewoodlab.paediatrics.ox.ac.uk/publications/334765
https://www.ncbi.nlm.nih.gov/pubmed/22647847
https://ora.ox.ac.uk/objects/uuid:53b69888-2b05-415c-8a81-a18d42af49b0
https://doi.org/10.1261/rna.030601.111
https://hdl.handle.net/20.500.11820/081b43f1-d235-435f-83bd-30ff67548572
https://www.pure.ed.ac.uk/ws/files/110243616/RNA_2012_Seow_1328_37.pdf

Markers of squamous cell carcinoma in sarco/endoplasmic reticulum Ca2+ ATPase 2 heterozygote mice keratinocytes

Autoři: Yu Mi Yang Jeong Hee Hong Shmuel Muallem a další

Přispěvatelé: Yu Mi Yang Jeong Hee Hong Shmuel Muallem a další

Zdroj: Progress in Biophysics and Molecular Biology. 103:81-87

Témata: Keratinocytes, 0301 basic medicine, Heterozygote, 0303 health sciences, Keratinocytes/metabolism, Carcinoma, Calcium Signaling/physiology, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Ca2þ signaling, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics, Mice, 03 medical and health sciences, SERCA2þ, Squamous Cell/metabolism, Squamous cell carcinoma, Carcinoma, Squamous Cell, Animals, Humans, Calcium Signaling, Squamous Cell/genetics, Biomarkers

Popis souboru: 81~87

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/19840814
http://www.sciencedirect.com/science/article/pii/S0079610709000698
https://www.sciencedirect.com/science/article/pii/S0079610709000698
https://europepmc.org/article/MED/19840814
http://www.ncbi.nlm.nih.gov/pubmed/19840814
https://yonsei.pure.elsevier.com/en/publications/markers-of-squamous-cell-carcinoma-in-sarcoendoplasmic-reticulum-
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101389

Cardiac contractile dysfunction during acute hyperglycemia due to impairment of SERCA by polyol pathway-mediated oxidative stress

Autoři: Tong, XY Hou, XY Kravtsov, GM a další

Zdroj: American Journal of Physiology-Cell Physiology. 299:C643-C653

Témata: Male, Tyrosine - metabolism, Superoxides - metabolism, Aldose reductase, Pyruvic Acid - metabolism, Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism, Hyperglycemia - metabolism - physiopathology, In Vitro Techniques, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Aldehyde Reductase, Lactic Acid - metabolism, Peroxynitrous Acid, Pyruvic Acid, Glutathione - metabolism, Myocardium - metabolism, Animals, Calcium Signaling, Lactic Acid, Myocardium, Aldehyde Reductase - physiology, Heart, Sorbitol dehydrogenase, Glutathione, Myocardial Contraction, Sarco(endo)plasmic reticulum Ca 2+-ATPase, Heart - physiopathology, Rats, 3. Good health, Perfusion, Oxidative Stress, Glucose, Glucose - pharmacology, Hyperglycemia, Acute Disease, Sprague-Dawley, Oxidation-Reduction, Peroxynitrous Acid - metabolism, Signal Transduction

Přístupová URL adresa: https://europepmc.org/articles/pmc2944313
https://pubmed.ncbi.nlm.nih.gov/20573996
https://pubmed.ncbi.nlm.nih.gov/20573996/
http://europepmc.org/articles/PMC2944313
https://ajpcell.physiology.org/content/299/3/C643
https://journals.physiology.org/doi/full/10.1152/ajpcell.00137.2010
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944313/
https://core.ac.uk/display/37950053
http://hdl.handle.net/10722/124488

Rosuvastatin inhibits norepinephrine-induced cardiac hypertrophy via suppression of Gh

Autoři: Woochul Chang Min Ji Cha Hye Jung Kim a další

Přispěvatelé: Woochul Chang Min Ji Cha Hye Jung Kim a další

Zdroj: European Journal of Pharmacology. 627:56-62

Témata: Myosin Light Chains/genetics, 0301 basic medicine, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Intracellular Space/drug effects, Cardiomegaly/metabolism, Norepinephrine/pharmacology, Proto-Oncogenes/genetics, Intracellular Space, Down-Regulation/drug effects, Messenger/metabolism, Norepinephrine, Extracellular Signal-Regulated MAP Kinases/metabolism, Cardiac Myosins/metabolism, Myocytes, Cardiac, Rosuvastatin Calcium, RNA, Small Interfering, Extracellular Signal-Regulated MAP Kinases, Cardiomyocytes, 0303 health sciences, Intracellular Space/metabolism, Pyrimidines/pharmacology, GTP-Binding Proteins/metabolism, 3. Good health, Protein Transport, Small Interfering/genetics, Cardiac/metabolism, G-proteins, Cardiomegaly/pathology, Calcium/metabolism, Myosin Light Chains, Down-Regulation, Cardiomegaly, Transfection, Rosuvastatin, 03 medical and health sciences, GTP-Binding Proteins, Cardiac Myosins/genetics, Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology, Proto-Oncogenes, Animals, RNA, Messenger, GTP-Binding Proteins/genetics, Myocytes, Cell Membrane/drug effects, Base Sequence, Cardiomegaly/chemically induced, Cell Membrane/metabolism, Cell Membrane, Hypertrophy, Protein Transport/drug effects, Sulfonamides/pharmacology, Rats, GTP-Binding Proteins/deficiency, Fluorobenzenes, Cardiac/drug effects, Pyrimidines, Fluorobenzenes/pharmacology, Myosin Light Chains/metabolism, RNA, Messenger/genetics, Calcium, Sprague-Dawley, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Cardiac Myosins

Popis souboru: 56~62

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/19883640
https://www.sciencedirect.com/science/article/pii/S0014299909009571
https://europepmc.org/article/MED/19883640
https://ir.ymlib.yonsei.ac.kr/handle/22282913/100556
https://yonsei.pure.elsevier.com/en/publications/rosuvastatin-inhibits-norepinephrine-induced-cardiac-hypertrophy-
https://pubmed.ncbi.nlm.nih.gov/19883640/

Alteration of RANKL-Induced Osteoclastogenesis in Primary Cultured Osteoclasts From SERCA2+/− Mice

Autoři: Dong Min Shin Aran Son Jeong Hee Hong a další

Přispěvatelé: Dong Min Shin Aran Son Jeong Hee Hong a další

Zdroj: Journal of Bone and Mineral Research. 24:1763-1769

Témata: Osteopetrosis/physiopathology, 0301 basic medicine, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, oste oclastogenesis, Cells, Osteoclasts/drug effects, Bone Marrow Cells/cytology, Osteoclasts, Bone Marrow Cells, Monocytes, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Mice, 03 medical and health sciences, Monocytes/drug effects, Bone Density, Osteogenesis, Osteogenesis/drug effects, Animals, Osteoclasts/enzymology, Calcium Signaling, Sarcoplasmic Reticulum Calcium-Transporting ATPases/deficiency, Cells, Cultured, NFATC Transcription Factors/metabolism, 0303 health sciences, Cultured, NFATC Transcription Factors, Monocytes/pathology, Monocytes/enzymology, RANK Ligand, sarco/endoplasmic reticulum Ca2+ATPase, RANKL, Bone Density/drug effects, [Ca2+]i oscillation, Protein Transport/drug effects, Osteopetrosis/pathology, Protein Transport, Osteoclasts/pathology, Osteopetrosis/enzymology, Osteopetrosis, Calcium Signaling/drug effects, osteopetrosis, RANK Ligand/pharmacology

Popis souboru: 1763~1769

Přístupová URL adresa: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1359/jbmr.090420
https://pubmed.ncbi.nlm.nih.gov/19419309
http://www.ncbi.nlm.nih.gov/pubmed/19419309
https://www.onlinelibrary.wiley.com/doi/abs/10.1359/jbmr.090420
http://onlinelibrary.wiley.com/doi/10.1359/jbmr.090420/abstract
https://asbmr.onlinelibrary.wiley.com/doi/pdf/10.1359/jbmr.090420
https://europepmc.org/abstract/MED/19419309
https://yonsei.pure.elsevier.com/en/publications/alteration-of-rankl-induced-osteoclastogenesis-in-primary-culture
https://ir.ymlib.yonsei.ac.kr/handle/22282913/104316

Deletion of TRPC3 in Mice Reduces Store-Operated Ca2+ Influx and the Severity of Acute Pancreatitis

Autoři: Jeong Hee Hong Lutz Birnbaumer Qin Li a další

Přispěvatelé: Jeong Hee Hong Lutz Birnbaumer Qin Li a další

Zdroj: Gastroenterology. 137:1509-1517

Témata: 0301 basic medicine, Pancreatitis/chemically induced, Sarcoplasmic Reticulum Calcium-Transporting ATPases/antagonists & inhibitors, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Indoles, Taurocholic Acid/metabolism, Severity of Illness Index, Membrane Potentials, Mice, Sarcoplasmic Reticulum/metabolism, Pancreatitis/prevention & control, Enzyme Inhibitors, Phosphorylation, eIF-2 Kinase/metabolism, Enzyme Inhibitors/pharmacology, Mice, Knockout, 0303 health sciences, Indoles/pharmacology, TRPC Cation Channels/genetics, Pancreatitis/pathology, 3. Good health, Sarcoplasmic Reticulum, Actins/metabolism, Acute Disease, Drug, Ceruletide, Calcium Signaling*/drug effects, Pancreas/metabolism, Knockout, Pancreas/pathology, Cholinergic Agonists, Trypsin/metabolism, Exocytosis, Dose-Response Relationship, 03 medical and health sciences, Pancreatitis/metabolism, Animals, TRPC Cation Channels/deficiency, Carbachol/pharmacology, Calcium Signaling, Pancreas, Dose-Response Relationship, Drug, Animal, Pancreas/drug effects, Cholinergic Agonists/pharmacology, Actins, Enzyme Activation, Disease Models, Animal, Pancreatitis, Sincalide/metabolism, Disease Models, Carbachol

Popis souboru: 1509~1517

Přístupová URL adresa: https://europepmc.org/articles/pmc2757493?pdf=render
https://pubmed.ncbi.nlm.nih.gov/19622358
https://www.gastrojournal.org/article/S0016-5085(09)01162-7/fulltext
http://www.sciencedirect.com/science/article/pii/S0016508509011627
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757493/
https://yonsei.pure.elsevier.com/en/publications/deletion-of-trpc3-in-mice-reduces-store-operated-casup2sup-influx
https://utsouthwestern.pure.elsevier.com/en/publications/deletion-of-trpc3-in-mice-reduces-store-operated-casup2sup-influx
https://www.sciencedirect.com/science/article/pii/S0016508509011627

Amiloride derivatives induce apoptosis by depleting ER Ca2+ stores in vascular endothelial cells

Autoři: Park, Kyu-Sang Poburko, Damon Wollheim, Claes a další

Zdroj: British Journal of Pharmacology, Vol. 156, No 8 (2009) pp. 1296-1304

Témata: 0301 basic medicine, Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism, Sodium-Hydrogen Exchangers, Diuretics/*toxicity, Apoptosis, Cell Cycle Proteins, Endoplasmic Reticulum, Guanidines, Transcription, Genetic/drug effects, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Amiloride, Endoplasmic Reticulum/*drug effects/metabolism, 03 medical and health sciences, Protein Phosphatase 1, Transcription Factor CHOP/genetics, Endothelial Cells/*drug effects/metabolism/pathology, Humans, Thapsigargin/pharmacology, Sulfones, Enzyme Inhibitors, ddc:612, Diuretics, Guanidines/pharmacology, Cell Cycle Proteins/genetics, Enzyme Inhibitors/pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Endothelial Cells, Calcium/*metabolism, Sodium-Hydrogen Antiporter/antagonists & inhibitors/metabolism, Hydrogen-Ion Concentration, Apoptosis/*drug effects, Antigens, Differentiation, Sulfones/pharmacology, Kinetics, Thapsigargin, Calcium, Amiloride/analogs & derivatives/*toxicity, Antigens, Differentiation/genetics, HeLa Cells

Popis souboru: application/pdf

Přístupová URL adresa: https://europepmc.org/articles/pmc2697743?pdf=render
https://pubmed.ncbi.nlm.nih.gov/19302589
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2009.00133.x
http://europepmc.org/articles/PMC2697743
https://core.ac.uk/display/60825616
https://yonsei.pure.elsevier.com/en/publications/amiloride-derivatives-induce-apoptosis-by-depleting-er-casup2sup-
http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2009.00133.x/full
https://pubmed.ncbi.nlm.nih.gov/19302589/
https://archive-ouverte.unige.ch/unige:20019
https://archive-ouverte.unige.ch/unige:20019
https://doi.org/10.1111/j.1476-5381.2009.00133.x

Testosterone-augmented contractile responses to α1- and β1-adrenoceptor stimulation are associated with increased activities of RyR, SERCA, and NCX in the heart

Autoři: Tsang, S Wong, SSC Wu, S a další

Zdroj: American Journal of Physiology-Cell Physiology. 296:C766-C782

Témata: Phenylephrine - Pharmacology, Sodium-Calcium Exchanger - Metabolism, Male, 0301 basic medicine, Time Factors, Myocardium - Enzymology - Metabolism, Norepinephrine - Pharmacology, Testosterone - Administration & Dosage - Metabolism, Receptors, Adrenergic, Beta-1 - Metabolism, Rats, Sprague-Dawley, Propanolamines, Norepinephrine, Phenylephrine, Receptors, Ventricular Function, Cells, Cultured, Adrenergic Alpha-1 Receptor Agonists, 0303 health sciences, Cultured, Calcium Signaling - Drug Effects, Adrenergic Beta-1 Receptor Agonists, Calcium Radioisotopes, Alpha-1 - Metabolism, Beta-1 - Metabolism, Adrenergic Agonists, Adrenergic, Adrenergic beta-1 Receptor Agonists, Calcium-Binding Proteins - Metabolism, Receptors, Adrenergic, Alpha-1 - Metabolism, Ventricular Function, Left - Drug Effects, Left - Drug Effects, Ventricular Pressure - Drug Effects, Ryanodine Receptor Calcium Release Channel - Metabolism, Cells, Adrenergic beta-Antagonists, Sarcoplasmic Reticulum Calcium-Transporting Atpases - Metabolism, 03 medical and health sciences, Propanolamines - Pharmacology, Caffeine, Animals, Calcium Signaling, Receptors, Androgen - Metabolism, Androgen - Metabolism, Isoproterenol - Pharmacology, Myocardium, Myocardial Contraction - Drug Effects, Calcium-Binding Proteins, Isoproterenol, Myocardial Contraction, Electric Stimulation, Rats, Sprague-Dawley, Adrenergic alpha-1 Receptor Agonists, Adrenergic Beta-Antagonists - Pharmacology, Orchiectomy, Caffeine - Pharmacology, Adrenergic Agonists - Pharmacology

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/19336623
https://www.physiology.org/doi/pdf/10.1152/ajpcell.00193.2008
http://hub.hku.hk/handle/10722/188346
https://ajpcell.physiology.org/content/ajpcell/296/4/C766.full.pdf
https://pubmed.ncbi.nlm.nih.gov/19336623/
https://journals.physiology.org/doi/full/10.1152/ajpcell.00193.2008
https://core.ac.uk/display/38029763
http://hdl.handle.net/10722/188346