Search Results - "Saccharomyces cerevisiae"

Allosteric regulation of fungal fatty acid synthesis.

Authors: Hasan SMN Samani EK Keszei AFA et al.

Source: Structure (London, England : 1993) [Structure] 2025 Dec 04; Vol. 33 (12), pp. 2041-2048.e4. Date of Electronic Publication: 2025 Oct 02.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/enzymology , Candida albicans*/enzymology , Candida albicans*/metabolism , Fatty Acids*/biosynthesis , Fatty Acid Synthases*/chemistry , Fatty Acid Synthases*/metabolism, Allosteric Regulation ; Crystallography, X-Ray ; Protein Binding ; Models, Molecular ; Binding Sites ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/metabolism

Enhanced production of sabinene by engineered Saccharomyces cerevisiae from corn hydrolysates.

Authors: Liu L Song L Qi C et al.

Source: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2025 Dec; Vol. 56 (4), pp. 2327-2337. Date of Electronic Publication: 2025 Aug 23.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Publishing Country of Publication: Brazil NLM ID: 101095924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4405 (Electronic) Linking ISSN: 15178382 NLM ISO Abbreviation: Braz J Microbiol Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Zea mays*/metabolism , Zea mays*/chemistry , Metabolic Engineering* , Monoterpenes*/metabolism, Fermentation ; CRISPR-Cas Systems ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism

Genotype-by-environment interactions shape ubiquitin-proteasome system activity.

Authors: Avery RR Collins MA Albert FW

Source: Genetics [Genetics] 2025 Nov 12; Vol. 231 (3).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print Cited Medium: Internet ISSN: 1943-2631 (Electronic) Linking ISSN: 00166731 NLM ISO Abbreviation: Genetics Subsets: MEDLINE

MeSH Terms: Proteasome Endopeptidase Complex*/metabolism , Proteasome Endopeptidase Complex*/genetics , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism , Gene-Environment Interaction* , Ubiquitin*/metabolism , Ubiquitin*/genetics, Genotype ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Proteolysis

The origin of septin ring size control in budding yeast.

Authors: Kukhtevich IV Persson S Padovani F et al.

Source: The EMBO journal [EMBO J] 2025 Nov; Vol. 44 (22), pp. 6466-6498. Date of Electronic Publication: 2025 Oct 02.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

MeSH Terms: Septins*/metabolism , Septins*/genetics , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/genetics , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/cytology, cdc42 GTP-Binding Protein, Saccharomyces cerevisiae/metabolism ; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae/genetics ; Cell Polarity ; Actins/metabolism ; Exocytosis ; Microfilament Proteins

Rational spatial rewiring of key enzymes enhances α-santalene production in Saccharomyces cerevisiae.

Authors: Tan W Tong S Gao Y et al.

Source: Bioresource technology [Bioresour Technol] 2025 Nov; Vol. 436, pp. 133027. Date of Electronic Publication: 2025 Jul 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Applied Science Country of Publication: England NLM ID: 9889523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2976 (Electronic) Linking ISSN: 09608524 NLM ISO Abbreviation: Bioresour Technol Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/enzymology , Saccharomyces cerevisiae*/genetics , Sesquiterpenes*/metabolism , Metabolic Engineering*/methods, Polycyclic Sesquiterpenes ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Endoplasmic Reticulum/metabolism ; Fermentation

Toxic Effects and Adaptive Response Mechanisms of Lignocellulose-Derived Phenolic Aldehydes in Saccharomyces cerevisiae during Cellulosic Ethanol Fermentation.

Authors: Yan Z Zhao H Chen F et al.

Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Oct 29; Vol. 73 (43), pp. 27587-27598. Date of Electronic Publication: 2025 Oct 16.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/drug effects , Ethanol*/metabolism , Lignin*/metabolism , Lignin*/chemistry , Aldehydes*/toxicity , Aldehydes*/metabolism , Cellulose*/metabolism , Phenols*/metabolism , Phenols*/toxicity, Fermentation ; Zea mays/metabolism ; Zea mays/chemistry ; Zea mays/microbiology ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Benzaldehydes/toxicity ; Benzaldehydes/metabolism

Heat shock induces silent ribosomes and reorganizes mRNA turnover.

Authors: Rahaman S Schiffelholz N Mittal N et al.

Source: Cell reports [Cell Rep] 2025 Oct 28; Vol. 44 (10), pp. 116447. Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH Terms: Heat-Shock Response*/genetics , RNA, Messenger*/metabolism , RNA, Messenger*/genetics , Ribosomes*/metabolism , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics, Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Protein Biosynthesis ; Heat-Shock Proteins/metabolism ; Heat-Shock Proteins/genetics ; Polyribosomes/metabolism ; RNA Stability

ERC accumulation depletes Sir2 from rDNA and induces cellular senescence by rDNA destabilization.

Authors: Yamamuro Y Uneme Y Li S et al.

Source: Nucleic acids research [Nucleic Acids Res] 2025 Oct 28; Vol. 53 (20).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

MeSH Terms: Sirtuin 2*/metabolism , Sirtuin 2*/genetics , DNA, Ribosomal*/metabolism , DNA, Ribosomal*/genetics , Silent Information Regulator Proteins, Saccharomyces cerevisiae*/metabolism , Silent Information Regulator Proteins, Saccharomyces cerevisiae*/genetics , Cellular Senescence*/genetics , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/genetics, Acetylation ; Genomic Instability ; Histones/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Transcription, Genetic ; Histone Acetyltransferases/genetics ; Histone Acetyltransferases/metabolism ; Promoter Regions, Genetic

Biosorption-based decontamination of mercury by Saccharomyces cerevisiae BY4741.

Authors: Azma N Wahyuni WT Astuti RI

Source: Archives of microbiology [Arch Microbiol] 2025 Oct 13; Vol. 207 (11), pp. 295. Date of Electronic Publication: 2025 Oct 13.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0410427 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-072X (Electronic) Linking ISSN: 03028933 NLM ISO Abbreviation: Arch Microbiol Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/drug effects , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/growth & development , Mercury*/metabolism , Mercury*/toxicity , Mercuric Chloride*/metabolism, Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Biodegradation, Environmental ; Microbial Sensitivity Tests ; Microbial Viability/drug effects ; Gene Expression Regulation, Fungal

Inducible chromosomal rearrangement reveals nonlinear polygenic dosage effects in driving aneuploid yeast traits.

Authors: Yin H Guo Z Zhou C et al.

Source: Nature communications [Nat Commun] 2025 Dec 04; Vol. 16 (1), pp. 10884. Date of Electronic Publication: 2025 Dec 04.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH Terms: Aneuploidy* , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/drug effects , Saccharomyces cerevisiae*/metabolism , Chromosomes, Fungal*/genetics , Gene Dosage* , Multifactorial Inheritance*/genetics, Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Epistasis, Genetic ; Phenotype ; Sirolimus/pharmacology ; Trehalose/biosynthesis

Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress.

Authors: Zedan M Schürch AP Heinrich S et al.

Source: Molecular cell [Mol Cell] 2025 Dec 04; Vol. 85 (23), pp. 4379-4392.e5. Date of Electronic Publication: 2025 Nov 24.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism , Protein Biosynthesis* , RNA, Messenger*/genetics , RNA, Messenger*/metabolism , RNA, Messenger*/biosynthesis , Transcription, Genetic* , Stress, Physiological* , RNA, Fungal*/genetics , RNA, Fungal*/metabolism, Gene Expression Regulation, Fungal ; Glucose/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; RNA Stability ; Time Factors

Structure of the transcriptional co-activator SAGA complex, including the histone acetyltransferase module.

Authors: Mattoo RUH Chen DH Bushnell DA et al.

Source: Molecular cell [Mol Cell] 2025 Dec 04; Vol. 85 (23), pp. 4333-4346.e4. Date of Electronic Publication: 2025 Nov 18.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

MeSH Terms: Histone Acetyltransferases*/chemistry , Histone Acetyltransferases*/metabolism , Histone Acetyltransferases*/genetics , Histone Acetyltransferases*/ultrastructure , Chaetomium*/genetics , Chaetomium*/enzymology , Fungal Proteins*/chemistry , Fungal Proteins*/genetics , Fungal Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/chemistry , Saccharomyces cerevisiae Proteins*/genetics , Saccharomyces cerevisiae Proteins*/metabolism , Trans-Activators*/chemistry , Trans-Activators*/genetics , Trans-Activators*/metabolism, Cryoelectron Microscopy ; Histones/metabolism ; Acetylation ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/enzymology ; Models, Molecular ; Transcription, Genetic ; Protein Conformation

SCR Organism: Chaetomium thermophilum

Proteasome-associated autoinflammatory syndromes: The impact of mutations in proteasome subunits on particle assembly, structure, and activity.

Authors: Huber EM Heinemeyer W Groll M

Source: Structure (London, England : 1993) [Structure] 2025 Dec 04; Vol. 33 (12), pp. 2084-2094.e5. Date of Electronic Publication: 2025 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

MeSH Terms: Proteasome Endopeptidase Complex*/genetics , Proteasome Endopeptidase Complex*/chemistry , Proteasome Endopeptidase Complex*/metabolism , Saccharomyces cerevisiae Proteins*/genetics , Saccharomyces cerevisiae Proteins*/chemistry , Saccharomyces cerevisiae Proteins*/metabolism, Humans ; Models, Molecular ; Crystallography, X-Ray ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Protein Subunits/genetics ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Point Mutation ; Mutation ; Amino Acid Substitution ; Protein Binding

Propolis impairs cellular proliferation by promoting oxidative damage and disrupting macromolecular composition in a yeast model.

Authors: Yardımcı BK Şimşek Özek N Güler A et al.

Source: Scientific reports [Sci Rep] 2025 Dec 03; Vol. 15 (1), pp. 43085. Date of Electronic Publication: 2025 Dec 03.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Propolis*/pharmacology , Saccharomyces cerevisiae*/drug effects , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Oxidative Stress*/drug effects , Cell Proliferation*/drug effects, Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Catalase/genetics

UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeast.

Authors: Bartolutti C Kim AJ Ma Y et al.

Source: Genes & development [Genes Dev] 2025 Dec 01; Vol. 39 (23-24), pp. 1434-1450. Date of Electronic Publication: 2025 Dec 01.

Publication Type: Journal Article

Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Electronic Cited Medium: Internet ISSN: 1549-5477 (Electronic) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE

MeSH Terms: Unfolded Protein Response*/genetics , Unfolded Protein Response*/physiology , Aneuploidy* , Proteostasis*/genetics , Saccharomyces cerevisiae*/growth & development , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/cytology , Saccharomyces cerevisiae*/physiology , Endoplasmic Reticulum*/metabolism, Endoplasmic Reticulum Stress ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Gene Expression Regulation, Fungal ; Protein Folding

Yeast cell fusion is mediated by spatially regulated secretion.

Authors: Machi U Mazur EE Sundlof A et al.

Source: Molecular biology of the cell [Mol Biol Cell] 2025 Dec 01; Vol. 36 (12), pp. ar151. Date of Electronic Publication: 2025 Oct 29.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/genetics , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/cytology, Cell Fusion ; Cell Wall/metabolism ; Membrane Fusion ; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae/metabolism ; cdc42 GTP-Binding Protein/metabolism

Unraveling gene expression: a beginner's guide from chromatin modifications to mRNA export in Saccharomyces cerevisiae .

Authors: Serrano-Quílez J Rodriguez-Navarro S

Source: Nucleus (Austin, Tex.) [Nucleus] 2025 Dec; Vol. 16 (1), pp. 2516909. Date of Electronic Publication: 2025 Jun 13.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101518322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-1042 (Electronic) Linking ISSN: 19491034 NLM ISO Abbreviation: Nucleus Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism , RNA, Messenger*/metabolism , RNA, Messenger*/genetics , Chromatin*/metabolism , Chromatin*/genetics , Gene Expression Regulation, Fungal*, Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Histones/metabolism

Mlh1-Pms1 couples ATP-driven DNA compaction with nick-dependent endonuclease activation.

Authors: Collingwood BW Bhalkar AN Manhart CM

Source: Nucleic acids research [Nucleic Acids Res] 2025 Nov 26; Vol. 53 (22).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

MeSH Terms: MutL Protein Homolog 1*/metabolism , Adenosine Triphosphate*/metabolism , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/genetics , DNA*/metabolism , DNA*/chemistry , Adenosine Triphosphatases*/metabolism, Proliferating Cell Nuclear Antigen/metabolism ; DNA Mismatch Repair ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Enzyme Activation ; Replication Protein C/metabolism ; MutL Proteins

eIF2D promotes 40S ribosomal subunit recycling during intrinsic ribosome destabilization.

Authors: Ichihara K Shiraishi T Chadani Y et al.

Source: Nucleic acids research [Nucleic Acids Res] 2025 Nov 26; Vol. 53 (22).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

MeSH Terms: Ribosome Subunits, Small, Eukaryotic*/metabolism , Ribosome Subunits, Small, Eukaryotic*/genetics , Eukaryotic Initiation Factor-2*/metabolism , Eukaryotic Initiation Factor-2*/genetics , Ribosomes*/metabolism , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/genetics, Protein Biosynthesis ; Humans ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Peptide Chain Initiation, Translational ; Protein Binding

Engineering yeast peroxisome assembly enables the increased production of acetyl-CoA and its derived 5-deoxyflavonoids.

Authors: Li Y Du B Li C et al.

Source: Nature communications [Nat Commun] 2025 Nov 25; Vol. 16 (1), pp. 10468. Date of Electronic Publication: 2025 Nov 25.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH Terms: Peroxisomes*/metabolism , Peroxisomes*/genetics , Acetyl Coenzyme A*/metabolism , Acetyl Coenzyme A*/biosynthesis , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Metabolic Engineering*/methods, Peroxins/genetics ; Peroxins/metabolism ; Flavanones/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics