Výsledky vyhľadávania - "STRUCTURE-activity relationships"

In vitro CB1 receptor activity of halogenated indazole synthetic cannabinoid receptor agonists

Autori: Green, Henrik McKenzie, Craig Hamra, Elias a ďalší

Zdroj: Archives of Toxicology. 99:3343-3353

Predmety: Halogenated synthetic cannabinoid receptor agonists, New psychoactive substances, CB1 cannabinoid receptor, Potency, Structure-activity relationships

Popis súboru: electronic

Prístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-213869
https://doi.org/10.1007/s00204-025-04082-4

In silico study of the potential of curcumin and its derivatives for increasing wild-type p53 expression and improving the function of p53 mutant R273H.

Autori: Nainggolan, Sarah Ika Rajuddin, Rajuddin Kamarlis, Reno Keumalazia a ďalší

Zdroj: Veterinary World. Mar2025, Vol. 18 Issue 3, p715-730. 16p.

Predmet: Tumor suppressor proteins, Structure-activity relationships, p53 protein, Molecular docking, Mutant proteins, Protein-ligand interactions, p53 antioncogene

Thiazolotriazoles: Their Biological Activity and Structure–Activity Relationships.

Autori: Purakkel, Umadevi Kizhakke Praveena, Ganji Blanch, Ewan W. a ďalší

Zdroj: Chemical Record. Nov2025, p1. 24p. 26 Illustrations.

Predmety: *STRUCTURE-activity relationships, *DRUG discovery, *ANTINEOPLASTIC agents, *THERAPEUTICS, *THIAZOLES, *ENZYME inhibitors, *HETEROCYCLIC compounds, *PHARMACEUTICAL chemistry

Cu‐SSZ‐13 Catalysts Designed Through Interzeolite Conversion Process From Different Structure Types of Zeolites for NH3‐SCR‐DeNOx: Structure‐Property Activity Relationships and Intermediates Determination

Autori: Robles, Alejandro Mollá Jabłońska, Magdalena Palčić, Ana a ďalší

Zdroj: ChemCatChem. 11/24/2025, Vol. 17 Issue 22, p1-16. 16p.

Predmety: *ZEOLITE catalysts, *STRUCTURE-activity relationships, *INTERMEDIATES (Chemistry), *CATALYSTS, *REACTION mechanisms (Chemistry), *ZEOLITES, *CATALYTIC reduction

Synthesis and Structure–Activity Relationship Studies of Truncated Artificial Analogues of Amphidinol 3.

Autori: Yasuno, Yoko Wakamiya, Yuma Mita, Yusuke a ďalší

Zdroj: Chemistry - An Asian Journal. 11/17/2025, Vol. 20 Issue 22, p1-8. 8p.

Predmety: *STRUCTURE-activity relationships, *ANTIFUNGAL agents, *STEREOCHEMISTRY, *POLYENES, *CHEMICAL synthesis, *POLYOLS, *SUZUKI reaction

Structure-activity relationships of bioactive peptides derived from legumes: significance and perspectives.

Autori: Zhao, Changhui He, Zichuan Regenstein, Joe M. a ďalší

Zdroj: Critical Reviews in Food Science & Nutrition. Nov2025, p1-13. 13p. 3 Illustrations.

Predmety: *STRUCTURE-activity relationships, *LEGUMES, *FUNCTIONAL foods, *DIETARY bioactive peptides, *PHARMACODYNAMICS, *HYDROLYSIS

Recent Progress in the Design of Aryl/Hetaryl Chalcone Derivatives as Improved Anticancer Agents: An Insightful Review Focusing on Structure‐Activity Relationship.

Autori: Yadav, Sidhant Vaishali Pundeer, Rashmi

Zdroj: ChemistrySelect. 11/10/2025, Vol. 10 Issue 42, p1-42. 42p.

Predmety: *CHALCONE, *STRUCTURE-activity relationships, *FLAVONOIDS, *CHEMOPREVENTION, *APOPTOSIS, *ANTINEOPLASTIC agents

Electron‐Donor Functionalization at the N‐Position of Ethylenediamine Derivatives for Enhanced Aluminum Corrosion Inhibition.

Autori: Liao, Huilian Huang, Haohua Li, Lin a ďalší

Zdroj: Chemistry - An Asian Journal. 11/3/2025, Vol. 20 Issue 21, p1-11. 11p.

Predmety: *ETHYLENEDIAMINE, *STRUCTURE-activity relationships, *ELECTROCHEMICAL analysis, *PROTECTIVE coatings, *ALUMINUM oxidation, *COORDINATE covalent bond, *ELECTRON donors, *LIGAND binding (Biochemistry)

Carbon–carbon bond formation reaction overactive sites of heterogeneous catalysts: understanding the role of catalytic sites with reaction mechanism, performance, stability, and product selectivity.

Autori: Sarfraz, Hina Shabanian, Saleh Shabbir, Samina a ďalší

Zdroj: Pure & Applied Chemistry. Nov2025, p1. 38p. 8 Illustrations.

Predmety: *HETEROGENEOUS catalysts, *STRUCTURE-activity relationships, *CARBON-carbon bonds, *DURABILITY, *CATALYSTS, *CATALYTIC activity, *CATALYTIC domains, *NANOPARTICLES

Benzohydrazide Analogs: Synthesis, Anticancer Screening, SAR, in Silico Molecular Docking, and ADMET Studies.

Autori: Solanki, Viral H. Patel, Umang P. Baloch, Muskanbanu M. a ďalší

Zdroj: ChemistrySelect. 11/3/2025, Vol. 10 Issue 41, p1-13. 13p.

Predmety: *MOLECULAR docking, *STRUCTURE-activity relationships, *CYTOTOXINS, *DRUG design, *PHARMACOKINETICS, *HYDRAZINE derivatives, *CELL lines

A Study on the Photothermal Catalytic Performance of Pt@MnO 2 for O-Xylene Oxidation.

Autori: Qiao, Rong Wang, Yanxuan Chen, Jiani a ďalší

Zdroj: Molecules. Nov2025, Vol. 30 Issue 21, p4193. 13p.

Predmety: *VOLATILE organic compounds, *STRUCTURE-activity relationships, *CATALYTIC activity, *PHOTOCATALYSIS, *CRYSTAL structure, *CATALYSTS, *OXIDATION-reduction reaction

Conformational Analysis of 3-Indoleacetamide: Unveiling Structural Rigidity in the Tryptophan-Derived Bioactive Molecule Family.

Autori: Municio, Sofía Mato, Sergio Alonso, José Luis a ďalší

Zdroj: Molecules. Nov2025, Vol. 30 Issue 21, p4156. 12p.

Predmety: *CONFORMATIONAL analysis, *STRUCTURE-activity relationships, *PHYSIOLOGY, *LASER spectroscopy, *BIOLOGICAL products, *INDOLE compounds

Screening and Validation of Functional Residues of the Antimicrobial Peptide Pp Rcys1.

Autori: Tao, Ming Fei, Zixun Sun, Aobo a ďalší

Zdroj: Biomolecules (2218-273X). Nov2025, Vol. 15 Issue 11, p1617. 19p.

Predmety: *ANTIMICROBIAL peptides, *STRUCTURE-activity relationships, *ANTIBACTERIAL agents, *MOLECULAR dynamics, *BACTERIAL cell walls, *AMINO acids, *SUSTAINABLE aquaculture

Structure–Activity Relationships of N -Acyl Dopamines in Inhibiting Myofibroblast Transdifferentiation of Retinal Pigment Epithelial Cells.

Autori: Zhao, Dandan Motheramgari, Vishaka Freudenberger, Riley a ďalší

Zdroj: Biomolecules (2218-273X). Nov2025, Vol. 15 Issue 11, p1526. 14p.

Predmety: *PROLIFERATIVE vitreoretinopathy, *STRUCTURE-activity relationships, *MYOFIBROBLASTS, *EXTRACELLULAR matrix, *RETINA, *CANNABINOIDS, *FIBROSIS, *DRUGS

Potent Broad‐Spectrum Antimicrobials Based on Indene‐Fused Thiazolidinone and Thiazolopyrimidine Scaffolds: Design, Synthesis, and Molecular Insights.

Autori: Aloudah, Salman A. Fadda, Ahmed A. Gaffer, Hatem E. a ďalší

Zdroj: Journal of Heterocyclic Chemistry. Nov2025, Vol. 62 Issue 11, p1776-1790. 15p.

Predmety: *DRUG development, *STRUCTURE-activity relationships, *THIAZOLE derivatives, *DRUG resistance in microorganisms, *HETEROCYCLIC compounds, *MOLECULAR docking, *THIAZOLES, *ANTI-infective agents

Design, Synthesis, and Structure–Activity Relationship of Some New Ciprofloxacin Hybrids as Antibacterial Agents.

Autori: Menteşe, Emre Yılmaz, Fatih Menteşe, Meltem a ďalší

Zdroj: Journal of Heterocyclic Chemistry. Nov2025, Vol. 62 Issue 11, p1473-1482. 10p.

Predmety: *CIPROFLOXACIN, *STRUCTURE-activity relationships, *GRAM-positive bacteria, *GRAM-negative bacteria, *CHEMICAL synthesis, *MOLECULAR hybridization, *ANTIBACTERIAL agents, *STRUCTURAL analysis (Science)

Targeting KRAS^G13C with cyclic linker based inhibitors to explore warhead orientation.

Autori: Kirschner, Tonia Rodriguez, João Moreira, Emerson Gonçalves a ďalší

Zdroj: Scientific Reports. 10/31/2025, Vol. 15 Issue 1, p1-16. 16p.

Predmety: *RAS oncogenes, *STRUCTURE-activity relationships, *NUCLEOSIDE derivatives, *CYCLIC compounds, *REACTIVITY (Chemistry), *CHEMICAL inhibitors

In silico and in vitro evaluation of N-heterocyclic derivatives as antimicrobials: ADMET analysis, SAR, and molecular docking.

Autori: Abbaoui, Zakariae Khibech, Oussama Oulous, Ahlam a ďalší

Zdroj: In Silico Pharmacology. 10/27/2025, Vol. 13 Issue 3, p1-18. 18p.

Predmety: *HETEROCYCLIC compound derivatives, *STRUCTURE-activity relationships, *ANTI-infective agents, *MOLECULAR docking, *CANDIDA albicans, *PHARMACOKINETICS, *STAPHYLOCOCCUS aureus, *ESCHERICHIA coli

Advanced Polyethylene Wax via Zinc‐Enhanced Metallocene Catalysis: Insights Into Molecular Weight Regulation Mechanisms.

Autori: Gui, Xiao Liu, Ying Wang, Shijia a ďalší

Zdroj: Macromolecular Reaction Engineering. Oct2025, p1. 12p. 11 Illustrations.

Predmety: *METALLOCENE catalysts, *STRUCTURE-activity relationships, *DENSITY functional theory, *CHAIN scission, *POLYMERS, *CHAIN transfer (Chemistry), *CATALYSTS, *CHEMICAL properties

Design, Synthesis, and Biological Evaluation of Lipid‐Modified Derivatives of Tunicamycins.

Autori: Yamamoto, Kazuki Sato, Toyotaka Mashalidis, Ellene H. a ďalší

Zdroj: Chemistry - A European Journal. 10/22/2025, Vol. 31 Issue 59, p1-7. 7p.

Predmety: *TUNICAMYCIN, *STRUCTURE-activity relationships, *STAPHYLOCOCCUS aureus, *ENTEROCOCCUS, *CYTOTOXINS, *FATTY acid derivatives, *ANTIBIOTICS