Suchergebnisse - "SCID"

TKK130 is a 3-Hydroxy-Propanamidine (HPA) with Potent Antimalarial In Vivo Activity and a High Barrier to Resistance.

Autoren: Knaab TC Moritz A Pessanha de Carvalho L et al.

Quelle: Journal of medicinal chemistry [J Med Chem] 2025 Jan 09; Vol. 68 (1), pp. 95-107. Date of Electronic Publication: 2024 Dec 26.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Antimalarials*/pharmacology , Antimalarials*/chemical synthesis , Antimalarials*/chemistry , Antimalarials*/pharmacokinetics , Plasmodium falciparum*/drug effects , Drug Resistance* , Mice, SCID*, Animals ; Humans ; Mice ; Structure-Activity Relationship ; Malaria/drug therapy ; Plasmodium berghei/drug effects ; Amidines/pharmacology ; Amidines/chemistry ; Amidines/chemical synthesis ; Amidines/pharmacokinetics ; Malaria, Falciparum/drug therapy ; Hemeproteins/antagonists & inhibitors ; Hemeproteins/metabolism

Adaptive immunity in Mus musculus influences the acquisition and abundance of Borrelia burgdorferi in Ixodes scapularis ticks.

Autoren: Koloski CW Adam H Hurry G et al.

Quelle: Applied and environmental microbiology [Appl Environ Microbiol] 2024 Dec 18; Vol. 90 (12), pp. e0129924. Date of Electronic Publication: 2024 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7605801 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5336 (Electronic) Linking ISSN: 00992240 NLM ISO Abbreviation: Appl Environ Microbiol Subsets: MEDLINE

MeSH-Schlagworte: Ixodes*/microbiology , Ixodes*/growth & development , Borrelia burgdorferi*/immunology , Borrelia burgdorferi*/genetics , Lyme Disease*/transmission , Lyme Disease*/microbiology , Lyme Disease*/immunology , Mice, SCID* , Mice, Inbred C57BL* , Larva*/microbiology , Adaptive Immunity*, Animals ; Mice ; Nymph/microbiology ; Nymph/growth & development ; Female

Construction a novel osteoporosis model in immune-deficient mice with natural ageing.

Autoren: Ma Z Qiu L Li J et al.

Quelle: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Nov 26; Vol. 735, pp. 150820. Date of Electronic Publication: 2024 Oct 11.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH-Schlagworte: Osteoporosis*/pathology , Osteoporosis*/genetics , Osteoporosis*/metabolism , Aging*/pathology , Disease Models, Animal* , Mice, Inbred NOD* , Mice, SCID*, Animals ; Mice ; Lumbar Vertebrae/pathology ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/metabolism ; Transforming Growth Factor beta1/metabolism ; Transforming Growth Factor beta1/genetics ; Smad3 Protein/metabolism ; Smad3 Protein/genetics ; Oxidative Stress ; X-Ray Microtomography ; Signal Transduction ; Female ; Humans ; Male ; Bone Density

Pneumocystis murina lesions in lungs of experimentally infected Cd40l ^-/- mice.

Autoren: Cappelleri A Canesi S Bertola L et al.

Quelle: Veterinary pathology [Vet Pathol] 2024 Nov; Vol. 61 (6), pp. 988-997. Date of Electronic Publication: 2024 May 17.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Sage Country of Publication: United States NLM ID: 0312020 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1544-2217 (Electronic) Linking ISSN: 03009858 NLM ISO Abbreviation: Vet Pathol Subsets: MEDLINE

MeSH-Schlagworte: Pneumocystis* , Lung*/pathology , Lung*/microbiology , CD40 Ligand*/deficiency , CD40 Ligand*/metabolism , CD40 Ligand*/genetics , Mice, SCID*, Animals ; Mice ; Mice, Knockout ; Pneumonia, Pneumocystis/pathology ; Pneumonia, Pneumocystis/microbiology ; Pneumonia, Pneumocystis/immunology ; Disease Models, Animal ; Immunohistochemistry ; Male

MRC2 expression modulates metabolism in acute myeloid leukemia stem cells.

Autoren: Mills TS Arnone M Görsch E et al.

Quelle: Cancer letters [Cancer Lett] 2025 Dec 28; Vol. 635, pp. 218068. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

MeSH-Schlagworte: Leukemia, Myeloid, Acute*/metabolism , Leukemia, Myeloid, Acute*/pathology , Leukemia, Myeloid, Acute*/genetics , Neoplastic Stem Cells*/metabolism , Neoplastic Stem Cells*/pathology , Lectins, C-Type*/metabolism , Lectins, C-Type*/genetics , Receptors, Mitogen*/metabolism , Receptors, Mitogen*/genetics , Receptors, Cell Surface*/metabolism , Receptors, Cell Surface*/genetics, Humans ; Animals ; Mice ; Glycolysis ; Mice, Inbred NOD ; Mice, SCID ; Collagen/metabolism ; Biomarkers, Tumor/metabolism ; Biomarkers, Tumor/genetics ; Cell Line, Tumor ; Gene Expression Regulation, Leukemic

TNF-α and IFN-γ differentially regulate AML cell susceptibility to CD70-antibody-mediated cytotoxicity.

Autoren: Sponheimer M White K Ulrich M et al.

Quelle: Journal for immunotherapy of cancer [J Immunother Cancer] 2025 Dec 04; Vol. 13 (12). Date of Electronic Publication: 2025 Dec 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE

MeSH-Schlagworte: Leukemia, Myeloid, Acute*/immunology , Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/pathology , Leukemia, Myeloid, Acute*/metabolism , CD27 Ligand*/metabolism , CD27 Ligand*/immunology , Tumor Necrosis Factor-alpha*/metabolism , Tumor Necrosis Factor-alpha*/pharmacology , Antibody-Dependent Cell Cytotoxicity* , Interferon-gamma*/metabolism , Interferon-gamma*/pharmacology, Humans ; Animals ; Mice ; Mice, SCID ; Female ; Male ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Killer Cells, Natural/immunology

Pharmacokinetic and biodistribution analysis of monoclonal antibodies: a comprehensive study of antibody biodistribution and partitioning coefficients in mice.

Autoren: Rabow Z Samiee I Desai P et al.

Quelle: MAbs [MAbs] 2025 Dec; Vol. 17 (1), pp. 2587580. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

MeSH-Schlagworte: Antibodies, Monoclonal*/pharmacokinetics, Animals ; Tissue Distribution ; Mice ; Mice, SCID ; Humans

Base edited "universal" donor CAR T-cell strategies for acute myeloid leukaemia.

Autoren: Kadirkamanathan R Georgiadis C Kloos A et al.

Quelle: Leukemia [Leukemia] 2025 Dec; Vol. 39 (12), pp. 2978-2987. Date of Electronic Publication: 2025 Oct 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

MeSH-Schlagworte: Gene Editing* , Immunotherapy, Adoptive*/methods , Leukemia, Myeloid, Acute*/therapy , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/immunology , T-Lymphocytes*/immunology, Animals ; Humans ; Mice ; HEK293 Cells ; HL-60 Cells ; Mice, Inbred NOD ; Mice, SCID ; Xenograft Model Antitumor Assays

T cell margination: investigating the detour of T cells following forimtamig treatment in humanized mice.

Autoren: O'Brien N Mueller JPJ Bröske AE et al.

Quelle: MAbs [MAbs] 2025 Dec; Vol. 17 (1), pp. 2440578. Date of Electronic Publication: 2024 Dec 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

MeSH-Schlagworte: Antibodies, Bispecific*/immunology , T-Lymphocytes*/immunology , Multiple Myeloma*/immunology , Multiple Myeloma*/therapy, Animals ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID

Integrated transcriptome profiling and in vitro analysis reveals MLN4924's role in inducing ferroptosis in acute myeloid leukemia.

Autoren: Jian J Guo Y Tang X et al.

Quelle: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2497041. Date of Electronic Publication: 2025 May 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH-Schlagworte: Ferroptosis*/drug effects , Ferroptosis*/genetics , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/metabolism , Leukemia, Myeloid, Acute*/pathology , Pyrimidines*/pharmacology , Pyrimidines*/therapeutic use , Gene Expression Profiling*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Mice, SCID ; Xenograft Model Antitumor Assays ; Amino Acid Transport System y+/genetics ; Amino Acid Transport System y+/metabolism ; Transcriptome ; Mice, Inbred NOD ; Phenylenediamines/pharmacology ; Reactive Oxygen Species/metabolism ; Cyclohexylamines ; Cyclopentanes

Anti-CTLA-4 Treatment Abrogates Co-stimulation Blockade-induced Acceptance of Transgenic Porcine Islets in Humanized Mice.

Autoren: Seissler J Figueiredo C Kemter E et al.

Quelle: Transplantation [Transplantation] 2025 Dec 01; Vol. 109 (12), pp. e691-e696. Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0132144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-6080 (Electronic) Linking ISSN: 00411337 NLM ISO Abbreviation: Transplantation Subsets: MEDLINE

MeSH-Schlagworte: Islets of Langerhans Transplantation*/methods , Islets of Langerhans Transplantation*/immunology , CTLA-4 Antigen*/immunology , CTLA-4 Antigen*/antagonists & inhibitors , CTLA-4 Antigen*/genetics , CTLA-4 Antigen*/metabolism , Graft Survival*/drug effects , Graft Rejection*/prevention & control , Graft Rejection*/immunology , Islets of Langerhans*/immunology , Islets of Langerhans*/drug effects , Islets of Langerhans*/metabolism , Diabetes Mellitus, Experimental*/surgery, Animals ; Humans ; Mice, Inbred NOD ; Swine ; Mice, SCID ; Mice, Transgenic ; Transplantation, Heterologous ; Cytokines/blood ; Mice ; Interleukin Receptor Common gamma Subunit/genetics ; Interleukin Receptor Common gamma Subunit/deficiency ; Time Factors

Biodistribution of free Francium-221 and Bismuth-213 in Tumour-bearing SCID mice after successful development of Actinium-225/Francium-221 radionuclide generator Set-up.

Autoren: Zitzmann-Kolbe S Remde Y Moen I et al.

Quelle: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2025 Dec; Vol. 53 (1), pp. 633-646. Date of Electronic Publication: 2025 Jul 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE

MeSH-Schlagworte: Bismuth*/pharmacokinetics , Bismuth*/therapeutic use , Bismuth*/chemistry , Radioisotopes*/pharmacokinetics , Radioisotopes*/therapeutic use , Radioisotopes*/chemistry , Actinium*/pharmacokinetics , Actinium*/chemistry , Actinium*/therapeutic use, Animals ; Mice ; Tissue Distribution ; Male ; Mice, SCID ; Humans ; Cell Line, Tumor ; Radiochemistry/instrumentation

NK92 cells stably transfected with CD16 are efficient against multiple myeloma cells ex vivo and in vivo , especially if combined with daratumumab.

Autoren: Giraldos D Galano-Frutos E Cambronero-Arregui L et al.

Quelle: Oncoimmunology [Oncoimmunology] 2025 Dec; Vol. 14 (1), pp. 2559782. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE

MeSH-Schlagworte: Multiple Myeloma*/therapy , Multiple Myeloma*/immunology , Multiple Myeloma*/pathology , Antibodies, Monoclonal*/pharmacology , Killer Cells, Natural*/immunology , Killer Cells, Natural*/metabolism , Killer Cells, Natural*/transplantation , Receptors, IgG*/genetics , Receptors, IgG*/immunology , Receptors, IgG*/metabolism , Immunotherapy, Adoptive*/methods, Humans ; Animals ; Mice ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Antibody-Dependent Cell Cytotoxicity/immunology ; Transfection ; Mice, SCID ; GPI-Linked Proteins

Dual nanobody-redirected and Bi-specific CD13/TIM3 CAR T cells eliminate AML xenografts without toxicity to human HSCs.

Autoren: Zhang X Feng Z Pranatharthi Haran A et al.

Quelle: Oncoimmunology [Oncoimmunology] 2025 Dec; Vol. 14 (1), pp. 2458843. Date of Electronic Publication: 2025 Feb 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE

MeSH-Schlagworte: Leukemia, Myeloid, Acute*/therapy , Leukemia, Myeloid, Acute*/immunology , Leukemia, Myeloid, Acute*/pathology , Hepatitis A Virus Cellular Receptor 2*/immunology , Single-Domain Antibodies*/immunology , Immunotherapy, Adoptive*/methods , Hematopoietic Stem Cells*/immunology , Receptors, Chimeric Antigen*/immunology , T-Lymphocytes*/immunology, Animals ; Humans ; Mice ; Xenograft Model Antitumor Assays ; Cell Line, Tumor ; Female ; Mice, SCID ; Mice, Inbred NOD

In Vivo Differentiation of hESC-Derived Neural Crest Cells into Trabecular Meshwork Cells.

Autoren: Su Y Duan H Zhu H et al.

Quelle: Tissue engineering. Part A [Tissue Eng Part A] 2025 Dec; Vol. 31 (23-24), pp. 1309-1318. Date of Electronic Publication: 2025 Jun 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101466659 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-335X (Electronic) Linking ISSN: 19373341 NLM ISO Abbreviation: Tissue Eng Part A Subsets: MEDLINE

MeSH-Schlagworte: Neural Crest*/cytology , Neural Crest*/metabolism , Trabecular Meshwork*/cytology , Trabecular Meshwork*/metabolism , Cell Differentiation* , Human Embryonic Stem Cells*/cytology , Human Embryonic Stem Cells*/metabolism, Animals ; Rabbits ; Humans ; Mice ; Mice, SCID ; Intraocular Pressure ; Mice, Inbred NOD

Immunotherapeutic targeting of NY-ESO-1 in malignant meningiomas with TCR-transduced T-cells.

Autoren: Sun MZ Contreras E Treger J et al.

Quelle: Journal of neuro-oncology [J Neurooncol] 2025 Dec; Vol. 175 (3), pp. 1079-1089. Date of Electronic Publication: 2025 Aug 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE

MeSH-Schlagworte: Meningioma*/therapy , Meningioma*/immunology , Meningioma*/pathology , Meningioma*/metabolism , Membrane Proteins*/metabolism , Membrane Proteins*/immunology , Meningeal Neoplasms*/therapy , Meningeal Neoplasms*/immunology , Meningeal Neoplasms*/pathology , Meningeal Neoplasms*/metabolism , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , T-Lymphocytes*/transplantation , Receptors, Antigen, T-Cell*/metabolism , Receptors, Antigen, T-Cell*/genetics , Receptors, Antigen, T-Cell*/immunology , Antigens, Neoplasm*/metabolism , Antigens, Neoplasm*/immunology , Immunotherapy, Adoptive*/methods, Animals ; Humans ; Mice ; Female ; Male ; Mice, Inbred NOD ; Mice, SCID ; Middle Aged ; Xenograft Model Antitumor Assays ; Aged ; Tumor Cells, Cultured ; Cell Line, Tumor ; Coculture Techniques

Cancer-testis antigen ACRBP: Cytotoxic response to its HLA-A2 restricted peptide and immune features in ovarian cancer.

Autoren: Zeng X Lin LN Li X et al.

Quelle: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2557096. Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

MeSH-Schlagworte: Ovarian Neoplasms*/immunology , Ovarian Neoplasms*/therapy , HLA-A2 Antigen*/immunology , T-Lymphocytes, Cytotoxic*/immunology , Antigens, Neoplasm*/immunology, Humans ; Female ; Animals ; Mice, SCID ; Dendritic Cells/immunology ; Mice ; Cell Line, Tumor ; CD8-Positive T-Lymphocytes/immunology ; Coculture Techniques ; Disease Models, Animal

A bispecific antibody-drug conjugate targeting CD7 and CD33 shows anti-tumor activity and improved tumor selectivity in an aggressive subtype of acute myeloid leukemia.

Autoren: Griffiths HBS Jones N Vitale M et al.

Quelle: MAbs [MAbs] 2025 Dec; Vol. 17 (1), pp. 2551205. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

MeSH-Schlagworte: Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/immunology , Leukemia, Myeloid, Acute*/pathology , Antibodies, Bispecific*/pharmacology , Antibodies, Bispecific*/immunology , Sialic Acid Binding Ig-like Lectin 3*/immunology , Sialic Acid Binding Ig-like Lectin 3*/antagonists & inhibitors , Immunoconjugates*/pharmacology , Antigens, CD7*/immunology, Humans ; Animals ; Mice ; Xenograft Model Antitumor Assays ; Cell Line, Tumor ; Female ; Mice, SCID ; Antigens, Neoplasm ; Tetraspanins

An integral membrane constitutively active heparanase enhances the tumor infiltration capability of NK cells.

Autoren: Liborio-Ramos S Quiros-Fernandez I Ilan N et al.

Quelle: Oncoimmunology [Oncoimmunology] 2025 Dec; Vol. 14 (1), pp. 2437917. Date of Electronic Publication: 2024 Dec 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE

MeSH-Schlagworte: Glucuronidase*/metabolism , Glucuronidase*/genetics , Killer Cells, Natural*/immunology, Animals ; Humans ; Mice ; Cell Line, Tumor ; Mice, SCID ; Cell Movement ; Neoplasms/immunology ; Neoplasms/pathology ; Neoplasms/therapy ; Mice, Inbred NOD ; Xenograft Model Antitumor Assays

Establishing a pediatric solid tumor PDX biobank for precision oncology research.

Autoren: Akemi Kido L Rodrigues Marusco M Aparecida da Silva E et al.

Quelle: Cancer biology & therapy [Cancer Biol Ther] 2025 Dec; Vol. 26 (1), pp. 2541974. Date of Electronic Publication: 2025 Aug 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137842 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8576 (Electronic) Linking ISSN: 15384047 NLM ISO Abbreviation: Cancer Biol Ther Subsets: MEDLINE

MeSH-Schlagworte: Precision Medicine*/methods , Biological Specimen Banks* , Neoplasms*/pathology , Neoplasms*/genetics, Humans ; Animals ; Mice ; Child ; Female ; Mice, SCID ; Mice, Inbred NOD ; Xenograft Model Antitumor Assays ; Male ; Child, Preschool