Výsledky vyhľadávania - "Ribavirin pharmacology"

Targeting the proteolytic processing of the viral glycoprotein precursor is a promising novel antiviral strategy against arenaviruses.

Autori: Rojek, J.M. Pasqual, G. Sanchez, A.B. a ďalší

Predmety: Animals, Antiviral Agents/pharmacology, Arenavirus/drug effects, Cell Line, Drug Delivery Systems/methods, Drug Synergism, Glycoproteins/metabolism, Humans, Lymphocytic choriomeningitis virus/drug effects, Peptide Hydrolases/metabolism, Peptides/pharmacology, Proprotein Convertases/antagonists & inhibitors, Proprotein Convertases/metabolism, Protease Inhibitors/pharmacology, Protease Inhibitors/therapeutic use, Ribavirin/pharmacology, Serine Endopeptidases/metabolism, Viral Envelope Proteins/metabolism

Relation: Journal of Virology; https://iris.unil.ch/handle/iris/252704; serval:BIB_FB4222F3912F; 000272564300054

Dostupnosť: https://iris.unil.ch/handle/iris/252704
https://doi.org/10.1128/JVI.01697-09

Durability of virologic response, risk of de novo hepatocellular carcinoma, liver function and stiffness 2 years after treatment with ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in the AMBER, real‐world experience study

Autori: R. Flisiak E. Janczewska M. Łucejko a ďalší

Zdroj: Journal of Viral Hepatitis. 25:1298-1305

Predmety: Male, Cyclopropanes, Liver Cirrhosis, chronic - drug therapy, Hepacivirus, Uracil - analogs & derivatives, 0302 clinical medicine, Liver cirrhosis - drug therapy, 2-Naphthylamine, Ritonavir - therapeutic use, Anilides, Treatment outcome, Liver neoplasms - epidemiology, Middle aged, chronic - virology, Uracil - pharmacology, Viral load - drug effects, Liver Neoplasms, Liver - pathology, Hepatitis C, hepatocellular - epidemiology, 3. Good health, Liver, Drug Therapy, Combination, Female, Drug therapy, Anilides - pharmacology, Uracil - therapeutic use, chronic - pathology, Liver cirrhosis - pathology, Adult, Carcinoma, Hepatocellular, Macrocyclic Compounds, Genotype, Liver cirrhosis - virology, Antiviral agents - therapeutic use, Liver cirrhosis - epidemiology, Lactams, Macrocyclic, Follow-up studies, Liver - physiopathology, Ribavirin - pharmacology, Antiviral Agents, Macrocyclic compounds - therapeutic use, 03 medical and health sciences, Sulfonamides - therapeutic use, chronic - epidemiology, Sulfonamides - pharmacology, Humans, hepatocellular carcinoma, liver cirrhosis, long-term follow-up, sustained virologic response, therapy, viral hepatitis C, Aged, combination, Carbamates - pharmacology, Carcinoma, Macrocyclic compounds - pharmacology, Poland - epidemiology, Hepatitis C, Chronic, Hepacivirus - genetics, Liver - drug effects, Ribavirin - therapeutic use, Ritonavir - pharmacology, Carbamates - therapeutic use, Anilides - therapeutic use, Hepacivirus - drug effects, Carbamates, Antiviral agents - pharmacology, Follow-Up Studies

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/29888828
https://onlinelibrary.wiley.com/doi/10.1111/jvh.12945
https://europepmc.org/article/MED/29888828
https://publicum.umed.lodz.pl/info/article/AML180e3455f40d456dbc7677bd27168393/
https://www.ncbi.nlm.nih.gov/pubmed/29888828
https://onlinelibrary.wiley.com/doi/abs/10.1111/jvh.12945
https://doi.org/10.1111/jvh.12945
https://ruj.uj.edu.pl/xmlui/handle/item/143548

Prevalence of NS5A resistance associated substitutions in patients with hepatitis C virus genotypes 1a and 3: Impact on current therapeutic strategies: Impact on current therapeutic strategies

Autori: Marta Grandal Berta Pernas Andrés Tabernilla a ďalší

Prispievatelia: Marta Grandal Berta Pernas Andrés Tabernilla a ďalší

Zdroj: RUC. Repositorio da Universidade da Coruña
instname

Predmety: RASs, Adult, Male, 0301 basic medicine, Genotype, Ribavirin/pharmacology, Mutation, Missense, Mutación missense, Antiviral Agents/pharmacology, Hepacivirus, Viral Nonstructural Proteins, Proteínas mutantes, NS5A, Antiviral Agents, 03 medical and health sciences, Hepatitis C, Chronic/drug therapy, Drug Resistance, Viral, Ribavirin, Prevalence, Humans, genotype 3, Sustitución de aminoácidos, Farmacorresistencia viral, Genotype 1a, Análisis de secuencia de ADN, Ribavirina, Sequence Analysis, DNA, Genotype 3, Hepatitis C, Chronic, Middle Aged, genotype 1a, 3. Good health, Viral Nonstructural Proteins/genetics, Amino Acid Substitution, Antivirales, Mutant Proteins, Mutant Proteins/genetics, Prevalencia, HCV-infection, Genotipo, Hepacivirus/classification, Hepatitis C crónica, Follow-Up Studies

Popis súboru: application/pdf

Prístupová URL adresa: https://ruc.udc.es/dspace/bitstream/2183/20798/2/Grndal_Prvlence.pdf
https://pubmed.ncbi.nlm.nih.gov/29427437
http://hdl.handle.net/2183/20798
https://onlinelibrary.wiley.com/doi/10.1002/jmv.25048
https://pubmed.ncbi.nlm.nih.gov/29427437/
https://www.ncbi.nlm.nih.gov/pubmed/29427437
https://hdl.handle.net/2183/20798
https://hdl.handle.net/10668/12111
https://biblio.vub.ac.be/vubir/(c980fe18-9b60-4b2f-a117-6b7b6e60b7ee).html

Ribavirin restores IFNα responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes

Autori: Testoni, Barbara Durantel, David Lebossé, Fanny a ďalší

Zdroj: Gut, Vol. 65, No 4 (2016) pp. 672-682

Predmety: Epigenomics, 0301 basic medicine, Interferon-alpha/genetics/pharmacology, Cells, Ribavirin/pharmacology, Blotting, Western, Messenger/drug effects, Gene Expression, Enzyme-Linked Immunosorbent Assay, Antiviral Agents/pharmacology, Gene Expression/drug effects, Hepacivirus, 616.07, ddc:616.07, Real-Time Polymerase Chain Reaction, Transfection, Virus Replication, Antiviral Agents, 03 medical and health sciences, Ribavirin, Humans, Immunoprecipitation, RNA, Messenger, Chronic, Cells, Cultured, ddc:616, Histone-Lysine N-Methyltransferase/metabolism, Virus Replication/drug effects, Cultured, Blotting, Hepacivirus/drug effects, Interferon-alpha, Histone-Lysine N-Methyltransferase, Hepatitis C, Chronic, Viral Load, Hepatocytes/drug effects/metabolism, Hepatitis C, 3. Good health, chronic viral hepatitis, gene regulation, hepatitis C, interferon, Hepatocytes, RNA, Western

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/26082258
https://gut.bmj.com/content/65/4/672.full.pdf
https://moh-it.pure.elsevier.com/en/publications/ribavirin-restores-ifn%CE%B1-responsiveness-in-hcv-infected-livers-by-
https://gut.bmj.com/content/65/4/672.short
https://gut.bmj.com/content/65/4/672
https://gut.bmj.com/content/gutjnl/65/4/672.full.pdf
https://pubmed.ncbi.nlm.nih.gov/26082258/
https://archive-ouverte.unige.ch/unige:126405
https://archive-ouverte.unige.ch/unige:126405
https://doi.org/10.1136/gutjnl-2014-309011
https://hdl.handle.net/11573/838626
https://doi.org/10.1136/gutjnl-2014-309011

Rapid viral response of once-daily TMC435 plus pegylated interferon/ribavirin in hepatitis C genotype-1 patients: a randomized trial

Autori: Manns, Michael Reesink, Hendrik Berg, Thomas a ďalší

Zdroj: Antiviral Therapy. 16(7):1021-1033

Predmety: Adult, Male, Adolescent, Double-blind method, Genotype, Antiviral agents - therapeutic use, Antiviral agents - administration & dosage, Antiviral agents - adverse effects, Recombinant proteins - therapeutic use, Ribavirin - pharmacology, Sulfonamides - administration & dosage, 3-ring - administration & dosage, Interferon-alpha - therapeutic use, viral - blood, Sulfonamides - therapeutic use, Simeprevir, Sulfonamides - adverse effects, Humans, Viral load, Middle aged, Aged, combination, Hepatitis C - virology, Interferon-alpha - administration & dosage, Ribavirin - administration & dosage, Polyethylene glycols - therapeutic use, Protease inhibitors - adverse effects, Protease inhibitors - therapeutic use, Ribavirin - therapeutic use, RNA, Female, 3-ring - adverse effects, Recombinant proteins - administration & dosage, Bilirubin - analysis, Drug therapy, Hepacivirus - drug effects, Hepatitis C - drug therapy, Heterocyclic compounds, 3-ring - therapeutic use, Polyethylene glycols - administration & dosage, Protease inhibitors - administration & dosage

In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds

Autori: Fan, KW Yuen, KY Kao, RYT a ďalší

Zdroj: J Clin Virol

Predmety: Adult, Male, 0301 basic medicine, Sars Virus - Drug Effects, Short Communication, Glycyrrhizic Acid - Chemistry - Pharmacology, Pyrimidinones - Pharmacology, Flavonoids - Chemistry - Pharmacology, Viral Plaque Assay, Microbial Sensitivity Tests, Pyrimidinones, Antiviral Agents, Lopinavir, Cell Line, 03 medical and health sciences, Rimantadine, Ribavirin, Humans, Epidemics, Ribavirin - Pharmacology, Flavonoids, 0303 health sciences, Severe Acute Respiratory Syndrome - Virology, Antiviral Agents - Pharmacology, Rimantadine - Pharmacology, Interferon-alpha, Drug Synergism, Interferon-beta, Middle Aged, Interferon-Alpha - Pharmacology, Glycyrrhizic Acid, 3. Good health, Severe acute respiratory syndrome, Interferon-Beta - Pharmacology, Severe acute respiratory syndrome-related coronavirus, Female, Antiviral compounds, Chlorogenic Acid, Chlorogenic Acid - Chemistry - Pharmacology, Interferon beta-1a

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/15288617
https://pubmed.ncbi.nlm.nih.gov/15288617/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128415
http://hub.hku.hk/handle/10722/163121
http://www.sciencedirect.com/science/article/pii/S1386653204000551
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128415
https://covid19.elsevierpure.com/pl/publications/in-vitro-susceptibility-of-10-clinical-isolates-of-sars-coronavir
http://hdl.handle.net/10722/163121

Viral hepatitis C

Autori: Yuen, MF Lung Lai, C Poynard, T a ďalší

Zdroj: The Lancet. 362:2095-2100

Predmety: Adult, Liver Cirrhosis, Interferon-alpha - pharmacology - therapeutic use, Genotype, Ribavirin - pharmacology - therapeutic use, Enzyme-Linked Immunosorbent Assay, HIV Infections, Comorbidity, Hepacivirus, Interferon alpha-2, Severity of Illness Index, Antiviral Agents, Hepatitis C, Chronic - diagnosis - drug therapy - epidemiology, Polyethylene Glycols, 03 medical and health sciences, 0302 clinical medicine, Viral - analysis - genetics - immunology, Ribavirin, Humans, Hepacivirus - drug effects - genetics - isolation & purification, Serotyping, HIV Infections - drug therapy - epidemiology, RNA, Viral - analysis - genetics - immunology, Polyethylene Glycols - pharmacology - therapeutic use, Interferon-alpha, Hepatitis C, Chronic, Antiviral Agents - pharmacology - therapeutic use, Hepatitis C, Recombinant Proteins, 3. Good health, Hepatitis C - diagnosis - drug therapy - epidemiology, Liver Cirrhosis - diagnosis - pathology, Chronic - diagnosis - drug therapy - epidemiology, Interferons - pharmacology - therapeutic use, Disease Progression, RNA, RNA, Viral, Interferons

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/14697814
https://www.sciencedirect.com/science/article/pii/S0140673603151094
https://www.ncbi.nlm.nih.gov/pubmed/14697814
https://pubmed.ncbi.nlm.nih.gov/14697814/
https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(03)15109-4.pdf
http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(03)15109-4.pdf
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(03)15109-4/fulltext
http://hdl.handle.net/10722/76969

Interferon and Ribavirin Therapy for Chronic Hepatitis C Virus Genotype 6: A Comparison with Genotype 1

Autori: Chan, AOO Wong, BCY Lai, CL a ďalší

Zdroj: The Journal of Infectious Diseases. 187:1071-1074

Predmety: Adult, Male, 0301 basic medicine, Genes, Viral, Genotype, Antiviral agents - therapeutic use, Ribavirin - pharmacology - therapeutic use, Hepacivirus, Interferon alpha-2, Hepatitis c, Antiviral Agents, Interferon alfa-2b - pharmacology - therapeutic use, 03 medical and health sciences, Ribavirin, Humans, Aged, Aged, 80 and over, Interferon-alpha, Hepatitis C, Chronic, Middle Aged, Recombinant Proteins, 3. Good health, chronic - drug therapy - virology, Drug Therapy, Combination, Female, Hepacivirus - drug effects - genetics, Hepatitis c, chronic - drug therapy - virology

Popis súboru: 85405 bytes; 3035 bytes; 2319 bytes; application/pdf; text/plain

Prístupová URL adresa: https://academic.oup.com/jid/article-pdf/187/7/1071/2393427/187-7-1071.pdf
https://pubmed.ncbi.nlm.nih.gov/12660921
http://hub.hku.hk/bitstream/10722/42154/1/80554.pdf
https://core.ac.uk/display/37881522
https://paperity.org/p/58709919/interferon-and-ribavirin-therapy-for-chronic-hepatitis-c-virus-genotype-6-a-comparison
http://hub.hku.hk/handle/10722/42154
https://www.ncbi.nlm.nih.gov/pubmed/12660921
http://hdl.handle.net/10722/42154

Serum procalcitonin levels in chronic hepatitis C patients under pegylated interferon-alpha plus ribavirin treatment

Autori: Elefsiniotis, I. S. Petrocheilou, A. Scarmeas, N. a ďalší

Zdroj: Journal of Clinical Virology. 37:329-331

Predmety: Adult, Calcitonin, Male, 0301 basic medicine, Calcitonin Gene-Related Peptide, Interferon alpha-2, Antiviral Agents, Polyethylene Glycols, 03 medical and health sciences, Ribavirin, Humans, Protein Precursors, Antiviral Agents/therapeutic use, Interferon-alpha, Hepatitis C, Chronic, Middle Aged, Ribavirin/*pharmacology/therapeutic use, Recombinant Proteins, 3. Good health, Protein Precursors/*blood, Hepatitis C, Chronic/drug therapy/*metabolism, Drug Therapy, Combination, Female, Polyethylene Glycols/*pharmacology/therapeutic use, Interferon-alpha/*pharmacology/therapeutic use, Calcitonin/*blood

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/16996792
https://pubmed.ncbi.nlm.nih.gov/16996792/
http://www.sciencedirect.com/science/article/pii/S138665320600309X
https://www.ncbi.nlm.nih.gov/pubmed/16996792
https://www.sciencedirect.com/science/article/pii/S138665320600309X
http://olympias.lib.uoi.gr/jspui/handle/123456789/18347

Hepatitis E virus replication in human intestinal cells

Autori: Olivier, Marion Lhomme, Sébastien Nayrac, Manon a ďalší

Prispievatelia: Olivier, Marion Lhomme, Sébastien Nayrac, Manon a ďalší

Zdroj: ISSN: 0017-5749.

Predmety: antiviral chemotherapy, enteric infections, epithelial cells, hepatitis E, MESH: Cells, Cultured, MESH: Epithelial Cells, MESH: Humans, MESH: Intestine, Small / cytology, MESH: RNA, Viral / genetics, MESH: Ribavirin / pharmacology, MESH: Sensitivity and Specificity, MESH: Virus Replication / genetics, MESH: Genotype, MESH: Hepatitis E virus / genetics, MESH: Hepatocytes / drug effects, MESH: Hepatocytes / virology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases

Relation: info:eu-repo/semantics/altIdentifier/pmid/31727684; PUBMED: 31727684

Dostupnosť: https://ut3-toulouseinp.hal.science/hal-03170436
https://doi.org/10.1136/gutjnl-2019-319004

Predicting treatment outcome following 24 weeks peginterferon alpha-2a/ribavirin therapy in patients infected with HCV genotype 1: utility of HCV-RNA at day 0, day 22, day 29, and week 6

Autori: Lukasiewicz, Esther Hellstrand, Kristoffer Westin, Johan a ďalší

Zdroj: Hepatology. 45(1):258-9

Predmety: Medical and Health Sciences, Medicin och hälsovetenskap, Antiviral Agents/pharmacology/ therapeutic use, Clinical Trials, Drug Therapy, Combination, Europe, Follow-Up Studies, Genotype, Hepacivirus/drug effects/ genetics, Hepatitis C/blood/ drug therapy/genetics, Humans, Interferon Alfa-2a/pharmacology/ therapeutic use, Multicenter Studies, Polyethylene Glycols/pharmacology/ therapeutic use, Predictive Value of Tests, RNA, Viral/ blood, Ribavirin/pharmacology/ therapeutic use, Treatment Outcome, Viral Load

Prístupová URL adresa: https://gup.ub.gu.se/publication/55067

Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin.

Autori: Dao Thi, V.L. Debing, Y. Wu, X. a ďalší

Predmety: Antiviral Agents/administration & dosage, Antiviral Agents/pharmacology, Chronic Disease, Drug Synergism, Drug Therapy, Combination, Hepatitis E/drug therapy, Hepatitis E virus/drug effects, Hepatitis E virus/physiology, Humans, In Vitro Techniques, RNA, Viral/drug effects, Viral/physiology, Ribavirin/administration & dosage, Ribavirin/pharmacology, Sofosbuvir/administration & dosage, Sofosbuvir/pharmacology, Virus Replication/drug effects

Relation: Gastroenterology; https://iris.unil.ch/handle/iris/140022; serval:BIB_9D8D1725E989; 000366832800025

Dostupnosť: https://iris.unil.ch/handle/iris/140022
https://doi.org/10.1053/j.gastro.2015.09.011

Ribavirin restores IFNα responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes

Autori: Testoni, Barbara Durantel, David Lebossé, Fanny a ďalší

Zdroj: ISSN: 0017-5749 ; Gut, vol. 65, no. 4 (2016) p. 672-682.

Predmety: info:eu-repo/classification/ddc/616, info:eu-repo/classification/ddc/616.07, Antiviral Agents/pharmacology, Blotting, Western, Cells, Cultured, Enzyme-Linked Immunosorbent Assay, Epigenomics, Gene Expression/drug effects, Hepacivirus/drug effects, Hepatitis C, Chronic, Hepatocytes/drug effects/metabolism, Histone-Lysine N-Methyltransferase/metabolism, Humans, Immunoprecipitation, Interferon-alpha/genetics/pharmacology, RNA, Messenger/drug effects, Real-Time Polymerase Chain Reaction, Ribavirin/pharmacology, Transfection, Viral Load, Virus Replication/drug effects

Relation: info:eu-repo/semantics/altIdentifier/pmid/26082258; unige:126405

Dostupnosť: https://archive-ouverte.unige.ch/unige:126405

Efficacy of Immunotherapy With TG4040, Peg-Interferon, and Ribavirin in a Phase 2 Study of Patients With Chronic HCV Infection

Autori: Vicente Carreño Adrian M. Di Bisceglie Patricia Zerr a ďalší

Zdroj: Gastroenterology. 147:119-131.e3

Predmety: Male, 0301 basic medicine, chronic - drug therapy, Polyethylene glycols - pharmacology, Viral vaccines - therapeutic use, Antiviral agents - adverse effects, Recombinant proteins - adverse effects, Hepacivirus, Polyethylene Glycols, chronic - immunology, Interferon-alpha - adverse effects, Immunotherapy - adverse effects, Vaccines, DNA, Treatment outcome, Middle aged, Interferon-alpha - pharmacology, Polyethylene glycols - adverse effects, Polyethylene glycols - therapeutic use, Viral vaccines - pharmacology, anti-idiotypic - metabolism, Middle Aged, Hepatitis C, Recombinant Proteins, Antibodies, Anti-Idiotypic, 3. Good health, Treatment Outcome, Drug Therapy, Combination, Female, Drug therapy, Immunotherapy, Adult, Viral vaccines - adverse effects, Genotype, Antiviral agents - therapeutic use, Recombinant proteins - therapeutic use, Ribavirin - pharmacology, Antiviral Agents, Antibodies, Interferon-alpha - therapeutic use, 03 medical and health sciences, Recombinant proteins - pharmacology, Ribavirin, Humans, Aged, combination, chronic - genetics, Interferon-alpha, Viral Vaccines, Hepatitis C, Chronic, Ribavirin - therapeutic use, Hepacivirus - drug effects, Antiviral agents - pharmacology, Ribavirin - adverse effects

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/24657484
https://www.gastrojournal.org/article/S0016-5085(14)00356-4/pdf
https://www.sciencedirect.com/science/article/pii/S0016508514003564
https://pubmed.ncbi.nlm.nih.gov/24657484/
https://www.gastrojournal.org/article/S0016-5085(14)00356-4/fulltext
https://www.ncbi.nlm.nih.gov/pubmed/24657484