Suchergebnisse - "Reverse Transcriptase Inhibitors/therapeutic use"

Reverse transcriptase inhibitors in Aicardi–Goutières syndrome: A crossover clinical trial: A crossover clinical trial

Autoren: Yanick J. Crow Tracy A. Briggs Despina Eleftheriou et al.

Quelle: Dev Med Child Neurol
AGS-RTIs Study Group 2025, 'Reverse transcriptase inhibitors in Aicardi-Goutières syndrome : A crossover clinical trial', Developmental Medicine and Child Neurology, vol. 67, no. 6, pp. 750-757. https://doi.org/10.1111/dmcn.16199

Schlagwörter: Male, Cyclopropanes, 0301 basic medicine, Reverse Transcriptase Inhibitors/therapeutic use, 0303 health sciences, Cross-Over Studies, Adolescent, Zidovudine/therapeutic use, Nervous System Malformations/drug therapy, Dideoxynucleosides/therapeutic use, 03 medical and health sciences, Treatment Outcome, Dideoxyadenosine/analogs & derivatives, Drug Therapy, Child, Preschool, Autoimmune Diseases of the Nervous System/drug therapy, Interferon-alpha/blood, Combination, Humans, Drug Therapy, Combination, Female, Original Article, Lamivudine/therapeutic use, Child, Preschool

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39630935

Lower Incidence of HIV-1 Blips Observed During Integrase Inhibitor–Based Combination Antiretroviral Therapy

Autoren: Suzan Dijkstra L. Marije Hofstra Tania Mudrikova et al.

Weitere Verfasser: Suzan Dijkstra L. Marije Hofstra Tania Mudrikova et al.

Quelle: JAIDS Journal of Acquired Immune Deficiency Syndromes. 89:575-582

Schlagwörter: integrase strand transfer inhibitors, Reverse Transcriptase Inhibitors/therapeutic use, protease inhibitors, HIV Infections/complications, HIV Infections, HIV Integrase Inhibitors/therapeutic use, Viremia/drug therapy, 03 medical and health sciences, 0302 clinical medicine, Antiretroviral Therapy, Highly Active/adverse effects, Antiretroviral Therapy, Highly Active, HIV Seropositivity, Journal Article, transient viremia, Humans, Pharmacology (medical), HIV Integrase Inhibitors, Viremia, Retrospective Studies, Research Support, Non-U.S. Gov't, Incidence, Viral Load, non-nucleoside reverse transcriptase inhibitors, 3. Good health, Infectious Diseases, HIV Seropositivity/complications, HIV-1, combination antiretroviral therapy, Reverse Transcriptase Inhibitors, blips

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/34966148
https://dspace.library.uu.nl/handle/1874/446447

Use of antiretroviral therapy in pregnancy and association with birth outcome among women living with HIV in Denmark: A nationwide, population‐based cohort study: A nationwide, population-based cohort study

Autoren: Ellen Moseholm Terese Lea Katzenstein Gitte Pedersen et al.

Quelle: HIV Med
Moseholm, E, Katzenstein, T L, Pedersen, G, Johansen, I S, Wienecke, L S, Storgaard, M, Obel, N & Weis, N 2022, 'Use of antiretroviral therapy in pregnancy and association with birth outcome among women living with HIV in Denmark : A nationwide, population-based cohort study', HIV Medicine, vol. 23, no. 9, pp. 1007-1018. https://doi.org/10.1111/hiv.13304
Moseholm, E, Katzenstein, T L, Pedersen, G, Johansen, I S, Wienecke, L S, Storgaard, M, Obel, N & Weis, N 2022, ' Use of antiretroviral therapy in pregnancy and association with birth outcome among women living with HIV in Denmark : A nationwide, population-based cohort study ', HIV Medicine, vol. 23, no. 9, pp. 1007-1018 . https://doi.org/10.1111/hiv.13304

Schlagwörter: TENOFOVIR DISOPROXIL FUMARATE, Reverse Transcriptase Inhibitors/therapeutic use, Denmark, antiretroviral therapy, INFANTS, HIV Infections/complications, HIV Infections, REGIMENS, Pregnancy Outcome/epidemiology, Cohort Studies, EFAVIRENZ, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Humans, RNA/therapeutic use, Pregnancy Complications, Infectious, RISK, Infectious/drug therapy, Pregnancy Complications, Infectious/drug therapy, Infant, Newborn, Pregnancy Outcome, Infant, birth outcome, Original Articles, Newborn, Denmark/epidemiology, 3. Good health, Pregnancy Complications, Premature Birth/epidemiology, PRETERM DELIVERY, SAFETY, INFECTED WOMEN, Premature Birth, RNA, Reverse Transcriptase Inhibitors, Female, pregnancy, SMOKING, Danish HIV Birth Cohort

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/35388607
https://vbn.aau.dk/da/publications/a6a7f198-d077-4537-ab1d-eed8a2b3c3a6
https://doi.org/10.1111/hiv.13304
https://vbn.aau.dk/ws/files/488640174/Moseholm_et_al_2022_Use_of_antiretroviral_therapy_in_pregnancy_and_association_with_birth_outcome_among_women_living_with_HIV_in_Denmark.pdf
http://www.scopus.com/inward/record.url?scp=85127616855&partnerID=8YFLogxK
https://curis.ku.dk/ws/files/319536101/Fulltext.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545374/pdf/HIV-23-1007.pdf
https://doi.org/10.1111/hiv.13304
https://pure.au.dk/portal/en/publications/dfc0a4f0-03e9-4aef-bd86-4cbc5c058318
http://www.scopus.com/inward/record.url?scp=85127616855&partnerID=8YFLogxK

Weight changes, metabolic syndrome and all‐cause mortality among Asian adults living with HIV

Autoren: Win Min Han Matthew G. Law Jun Yong Choi et al.

Weitere Verfasser: Win Min Han Matthew G. Law Jun Yong Choi et al.

Quelle: HIV Medicine. 23:274-286

Schlagwörter: HIV Infections* / drug therapy, Adult, Male, Metabolic Syndrome, Metabolic Syndrome* / complications, weight gain, HIV Infections, Reverse Transcriptase Inhibitors / therapeutic use, Metabolic Syndrome* / epidemiology, HIV Infections* / complications, metabolic syndrome, CD4 Lymphocyte Count, 3. Good health, Asian people living with HIV, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, HIV/AIDS, all-cause mortality, Humans, Reverse Transcriptase Inhibitors, Metabolic Syndrome* / drug therapy

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/34816562
https://onlinelibrary.wiley.com/doi/abs/10.1111/hiv.13211
https://pubmed.ncbi.nlm.nih.gov/34816562/
https://www.ncbi.nlm.nih.gov/pubmed/34816562

Impact of recommendation updates in well-controlled patients on nonrecommended antiretroviral therapies: the Swiss HIV cohort study.

Autoren: Boillat-Blanco, N. Darling, K.E. Taffe, P. et al.

Schlagwörter: Adult, Cardiovascular Diseases/chemically induced, Cardiovascular Diseases/prevention & control, Chi-Square Distribution, Cholesterol/blood, Diabetes Complications/complications, Didanosine/therapeutic use, Drug Therapy, Combination/standards, Female, Guideline Adherence, HIV Infections/complications, HIV Infections/drug therapy, HIV Protease Inhibitors/therapeutic use, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Physician's Practice Patterns, Practice Guidelines as Topic, Retrospective Studies, Reverse Transcriptase Inhibitors/therapeutic use, Sex Factors, Statistics, Nonparametric, Stavudine/therapeutic use, Switzerland, Viral Load

Dateibeschreibung: application/pdf

Relation: Journal of Acquired Immune Deficiency Syndromes; https://iris.unil.ch/handle/iris/89463; serval:BIB_5EE95A0D4F7F; 000314459500014

Verfügbarkeit: https://iris.unil.ch/handle/iris/89463
https://doi.org/10.1097/QAI.0b013e31827b626a

Reducing tuberculosis incidence by tuberculin skin testing, preventive treatment, and antiretroviral therapy in an area of low tuberculosis transmission

Autoren: Elzi, L. Schlegel, M. Weber, R. et al.

Schlagwörter: Adult Anti-HIV Agents/*therapeutic use CD4 Lymphocyte Count Drug Therapy, Combination Female HIV Infections/*drug therapy Humans Incidence Male Prevalence RNA, Viral/blood Reverse Transcriptase Inhibitors/*therapeutic use Tuberculin Test/*methods Tuberculosis/diagnosis/drug therapy/*epidemiology/*prevention & control

Dateibeschreibung: application/pdf

Relation: Clinical Infectious Diseases; https://iris.unil.ch/handle/iris/76387; serval:BIB_23B13C5E19B9; 000242479500016

Verfügbarkeit: https://iris.unil.ch/handle/iris/76387
https://doi.org/10.1086/510080

Long-term responses to treatment including ritonavir or nelfinavir in HIV-1-infected children. Pediatric AIDS Group of Switzerland

Autoren: Nadal, D. Steiner, F. Cheseaux, J. J. et al.

Schlagwörter: Adolescent CD4 Lymphocyte Count Child Child, Preschool Drug Therapy, Combination Female HIV Infections/blood/*drug therapy/virology HIV Protease Inhibitors/*therapeutic use *HIV-1/genetics/isolation & purification Humans Infant Male Nelfinavir/adverse effects/*therapeutic use Prospective Studies RNA, Messenger/blood RNA, Viral/blood Reverse Transcriptase Inhibitors/*therapeutic use Ritonavir/adverse effects/*therapeutic use

Relation: Infection; https://iris.unil.ch/handle/iris/70509; serval:BIB_0E5523482DA2; 000089932300007

Verfügbarkeit: https://iris.unil.ch/handle/iris/70509
https://doi.org/10.1007/s150100070021

Prevalence and effect of pre-treatment drug resistance on the virological response to antiretroviral treatment initiated in HIV-infected children - a EuroCoord-CHAIN-EPPICC joint project.

Autoren: Ngo-Giang-Huong, N. Wittkop, L. Judd, A. et al.

Weitere Verfasser: Ngo-Giang-Huong, N. Wittkop, L. Judd, A. et al.

Schlagwörter: Adolescent, Anti-HIV Agents/therapeutic use, CD4 Lymphocyte Count, Child, Preschool, Drug Resistance, Viral/drug effects, Viral/genetics, Drug Therapy, Combination, Female, HIV Infections/drug therapy, HIV Infections/mortality, HIV Infections/virology, HIV-1/drug effects, Humans, Infant, Kaplan-Meier Estimate, Male, Mutation, Reverse Transcriptase Inhibitors/therapeutic use, Viral Load/drug effects, Children, First-line combination antiretroviral therapy, HIV, Pre-treatment drug resistance mutations, Virological failure

Dateibeschreibung: application/pdf

Relation: BMC Infectious Diseases; https://iris.unil.ch/handle/iris/59418; serval:BIB_2E1EBE8BEC65; 000387727900001

Verfügbarkeit: https://iris.unil.ch/handle/iris/59418
https://doi.org/10.1186/s12879-016-1968-2

The comparative effectiveness of NRTI-sparing dual regimens in emulated trials using observational data from the Swiss HIV Cohort Study.

Autoren: Young, J. Scherrer, A.U. Calmy, A. et al.

Weitere Verfasser: Young, J. Scherrer, A.U. Calmy, A. et al.

Schlagwörter: Adult, Aged, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Cohort Studies, Female, HIV Infections/drug therapy, HIV Infections/immunology, HIV Infections/virology, HIV-1/drug effects, Humans, Male, Middle Aged, Randomized Controlled Trials as Topic, Reverse Transcriptase Inhibitors/administration & dosage, Reverse Transcriptase Inhibitors/adverse effects, Reverse Transcriptase Inhibitors/therapeutic use, Treatment Outcome, Viral Load

Relation: Antiviral Therapy; https://iris.unil.ch/handle/iris/247698; serval:BIB_EE3F2AF63928; 000525652500003

Verfügbarkeit: https://iris.unil.ch/handle/iris/247698
https://doi.org/10.3851/IMP3310

Survival of infantile fulminant hepatitis B and treatment with Lamivudine

Autoren: Laubscher, B. Gehri, M. Roulet, M. et al.

Schlagwörter: Hepatitis B/complications/*drug therapy Hepatitis B Surface Antigens/drug effects/metabolism Hepatitis B virus/*drug effects Humans Infant Lamivudine/*therapeutic use Liver Failure/*drug therapy/etiology Male Reverse Transcriptase Inhibitors/*therapeutic use Survival Analysis Treatment Outcome

Relation: Journal of Pediatric Gastroenterology and Nutrition; https://iris.unil.ch/handle/iris/240874; serval:BIB_FC1B37A76851; 000228078400022

Verfügbarkeit: https://iris.unil.ch/handle/iris/240874
https://doi.org/10.1097/01.MPG.0000144374.63230.44

Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice?

Autoren: Mugavero, M.J. May, M. Harris, R. et al.

Weitere Verfasser: Mugavero, M.J. May, M. Harris, R. et al.

Schlagwörter: Adolescent, Adult, Anti-Retroviral Agents/therapeutic use, Disease-Free Survival, Drug Interactions, Drug Resistance, Viral, Drug Therapy, Combination, Epidemiologic Methods, Female, HIV Infections/drug therapy, HIV Infections/immunology, HIV-1, Humans, Male, Middle Aged, Odds Ratio, RNA, Viral/metabolism, Reverse Transcriptase Inhibitors/therapeutic use, Treatment Outcome, Viral Load, Young Adult

Relation: AIDS; https://iris.unil.ch/handle/iris/235431; serval:BIB_E64306C44B49; 000261772300008

Verfügbarkeit: https://iris.unil.ch/handle/iris/235431
https://doi.org/10.1097/QAD.0b013e328318f130

Polymorphism of HIV type 1 gag p7/p1 and p1/p6 cleavage sites: clinical significance and implications for resistance to protease inhibitors

Autoren: Bally, F. Martinez, R. Peters, S. et al.

Schlagwörter: Capsid/genetics *Capsid Proteins Disease Progression Drug Resistance, Microbial/genetics Drug Therapy, Combination Fusion Proteins, gag-pol/genetics/metabolism Gene Products, gag/*genetics HIV Infections/drug therapy/physiopathology/*virology HIV Protease/genetics HIV Protease Inhibitors/*pharmacology/therapeutic use HIV-1/*drug effects/genetics/physiology Humans Mutation Polymorphism, Genetic/*genetics RNA, Viral/blood Reverse Transcriptase Inhibitors/therapeutic use *Viral Proteins

Relation: AIDS Research and Human Retroviruses; https://iris.unil.ch/handle/iris/221610; serval:BIB_A98506B54078; 000088921400002

Verfügbarkeit: https://iris.unil.ch/handle/iris/221610
https://doi.org/10.1089/08892220050116970

Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study.

Autoren: Yang, W.L. Kouyos, R.D. Scherrer, A.U. et al.

Weitere Verfasser: Yang, W.L. Kouyos, R.D. Scherrer, A.U. et al.

Schlagwörter: Adult, Antiretroviral Therapy, Highly Active/methods, Drug Resistance, Viral, Female, HIV Infections/drug therapy, HIV-1, Humans, Male, Middle Aged, Nucleosides/therapeutic use, Nucleotides/therapeutic use, Reverse Transcriptase Inhibitors/therapeutic use, Switzerland, Treatment Failure

Dateibeschreibung: application/pdf

Relation: Journal of Antimicrobial Chemotherapy; https://iris.unil.ch/handle/iris/213096; serval:BIB_78500C13A281; 000368246800022

Verfügbarkeit: https://iris.unil.ch/handle/iris/213096
https://doi.org/10.1093/jac/dkv257

Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics.

Autoren: Kühnert, D. Kouyos, R. Shirreff, G. et al.

Weitere Verfasser: Kühnert, D. Kouyos, R. Shirreff, G. et al.

Schlagwörter: Adaptation, Biological/genetics, Anti-HIV Agents/therapeutic use, Antiretroviral Therapy, Highly Active, Databases, Factual, Drug Resistance, Viral/genetics, Genetic Fitness, Genotype, HIV Infections/drug therapy, HIV Infections/epidemiology, HIV Infections/virology, HIV-1/genetics, Humans, Mutation, Mutation Rate, Phylogeny, Reverse Transcriptase Inhibitors/therapeutic use, Switzerland/epidemiology

Dateibeschreibung: application/pdf

Relation: PLoS Pathogens; https://iris.unil.ch/handle/iris/212130; serval:BIB_6E944D8BBF5C; 000426477000038

Verfügbarkeit: https://iris.unil.ch/handle/iris/212130
https://doi.org/10.1371/journal.ppat.1006895

Successful efavirenz dose reduction guided by therapeutic drug monitoring.

Autoren: Fayet Mello, A. Buclin, T. Decosterd, L.A. et al.

Schlagwörter: Anti-HIV Agents/administration & dosage, Anti-HIV Agents/therapeutic use, Bayes Theorem, Benzoxazines/administration & dosage, Benzoxazines/therapeutic use, Drug Monitoring/methods, Female, HIV Infections/drug therapy, HIV Infections/virology, HIV-1/drug effects, Humans, Male, Middle Aged, Reverse Transcriptase Inhibitors/administration & dosage, Reverse Transcriptase Inhibitors/therapeutic use, Treatment Outcome

Relation: Antiviral Therapy; https://iris.unil.ch/handle/iris/197520; serval:BIB_AC2598E4B289

Verfügbarkeit: https://iris.unil.ch/handle/iris/197520
https://doi.org/10.3851/IMP1742

Comparison of Population Pharmacokinetics Based on Steady-State Assumption Versus Electronically Monitored Adherence to Lopinavir, Atazanavir, Efavirenz, and Etravirine: A Retrospective Study.

Autoren: Fuchs, A. Rotzinger, A. Cavassini, M. et al.

Schlagwörter: Atazanavir Sulfate/blood, Atazanavir Sulfate/pharmacokinetics, Atazanavir Sulfate/therapeutic use, Benzoxazines/blood, Benzoxazines/pharmacokinetics, Benzoxazines/therapeutic use, Drug Monitoring/methods, HIV Infections/drug therapy, HIV Protease Inhibitors/blood, HIV Protease Inhibitors/pharmacokinetics, Humans, Lopinavir/blood, Lopinavir/pharmacokinetics, Lopinavir/therapeutic use, Medication Adherence, Pyridazines/blood, Pyridazines/pharmacokinetics, Pyridazines/therapeutic use, Retrospective Studies, Reverse Transcriptase Inhibitors/blood, Reverse Transcriptase Inhibitors/pharmacokinetics, Reverse Transcriptase Inhibitors/therapeutic use

Relation: Therapeutic Drug Monitoring; https://iris.unil.ch/handle/iris/195901; serval:BIB_9C5EDAE96F2A; 000381427700012

Verfügbarkeit: https://iris.unil.ch/handle/iris/195901
https://doi.org/10.1097/FTD.0000000000000297

Dynamic correlation of apoptosis and immune activation during treatment of HIV infection

Autoren: Bradley, A. D. Parato, K. Cameron, D. W. et al.

Schlagwörter: Adolescent Adult Anti-HIV Agents/therapeutic use Antigens, CD95/biosynthesis *Apoptosis CASP8 and FADD-Like Apoptosis Regulating Protein Carrier Proteins/biosynthesis Drug Therapy, Combination HIV Infections/*drug therapy/*immunology/virology HIV Protease Inhibitors/therapeutic use Humans *Intracellular Signaling Peptides and Proteins Middle Aged Nelfinavir/therapeutic use Nucleosides/therapeutic use Reverse Transcriptase Inhibitors/therapeutic use Saquinavir/therapeutic use T-Lymphocytes/immunology

Relation: Cell Death & Differentiation; https://iris.unil.ch/handle/iris/164137; serval:BIB_93E338F98BBB; 000080272500007

Verfügbarkeit: https://iris.unil.ch/handle/iris/164137
https://doi.org/10.1038/sj.cdd.4400509

Virological outcome and management of persistent low-level viraemia in HIV-1-infected patients: 11 years of the Swiss HIV Cohort Study.

Autoren: Boillat-Blanco, N. Darling, K.E. Schoni-Affolter, F. et al.

Weitere Verfasser: Boillat-Blanco, N. Darling, K.E. Schoni-Affolter, F. et al.

Schlagwörter: Adult, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Disease Management, Female, HIV Infections/drug therapy, HIV Infections/immunology, HIV Protease Inhibitors/therapeutic use, HIV-1/drug effects, HIV-1/physiology, Humans, Male, Middle Aged, Retrospective Studies, Reverse Transcriptase Inhibitors/therapeutic use, Switzerland, Treatment Outcome, Viral Load/drug effects, Viremia/drug therapy, Viremia/immunology, Virus Replication/drug effects

Relation: Antiviral Therapy; https://iris.unil.ch/handle/iris/156321; serval:BIB_EBE639128EA3; 000359909200007

Verfügbarkeit: https://iris.unil.ch/handle/iris/156321
https://doi.org/10.3851/IMP2815

Response to first protease inhibitor- and efavirenz-containing antiretroviral combination therapy. The Swiss HIV Cohort Study

Autoren: Friedl, A. C. Ledergerber, B. Flepp, M. et al.

Schlagwörter: Adult Aged Anti-HIV Agents/*therapeutic use CD4 Lymphocyte Count Cohort Studies Drug Therapy, Combination Female HIV Infections/*drug therapy HIV Protease Inhibitors/*therapeutic use HIV-1/physiology Humans Male Middle Aged Oxazines/*therapeutic use Prospective Studies RNA, Viral/blood Reverse Transcriptase Inhibitors/*therapeutic use Treatment Outcome Viral Load

Relation: AIDS; https://iris.unil.ch/handle/iris/141780; serval:BIB_BF7702ACC5A7; 000171375100008

Verfügbarkeit: https://iris.unil.ch/handle/iris/141780
https://doi.org/10.1097/00002030-200109280-00008

Impact of lamivudine on the risk of liver-related death in 2,041 HBsAg- and HIV-positive individuals: results from an inter-cohort analysis

Autoren: Puoti, M. Cozzi-Lepri, A. Arici, C. et al.

Schlagwörter: Adult CD4 Lymphocyte Count Carcinoma, Hepatocellular/*drug therapy/immunology/mortality Drug Therapy, Combination Female HIV Infections/*drug therapy/immunology/mortality Hepatitis B/*drug therapy/immunology/mortality Hepatitis B Surface Antigens/blood Hepatitis C Antibodies/blood Humans Lamivudine/*therapeutic use Liver Neoplasms/*drug therapy/immunology/mortality Male Retrospective Studies Reverse Transcriptase Inhibitors/*therapeutic use Risk Factors Survival Analysis

Relation: Antiviral Therapy; https://iris.unil.ch/handle/iris/112355; serval:BIB_0AEDB213C1C3; 000239984700004

Verfügbarkeit: https://iris.unil.ch/handle/iris/112355