Suchergebnisse - "Reperfusion Injury/prevention & control"

Malonate given at reperfusion prevents post-myocardial infarction heart failure by decreasing ischemia/reperfusion injury

Autoren: Jiro Abe Ana Vujic Hiran A. Prag et al.

Weitere Verfasser: Jiro Abe Ana Vujic Hiran A. Prag et al.

Quelle: Basic Res Cardiol
Abe, J, Vujic, A, Prag, H A, Murphy, M P & Krieg, T 2024, 'Malonate given at reperfusion prevents post-myocardial infarction heart failure by decreasing ischemia/reperfusion injury', Basic Research in Cardiology, vol. 119, no. 4, pp. 691-697. https://doi.org/10.1007/s00395-024-01063-z

Schlagwörter: Male, Succinate, Time Factors, Myocardium/metabolism, Malonates/pharmacology, Myocardial Infarction, Myocardial Reperfusion Injury/prevention & control, Myocardial Reperfusion Injury, Ischemia/reperfusion injury, Inbred C57BL, Left/drug effects, Ventricular Function, Left, Heart Failure/prevention & control, Mice, Ventricular Function, Animals, Ventricular Function, Left/drug effects, Myocytes, Cardiac, Myocardial Infarction/metabolism, Heart Failure, Myocytes, Animal, Myocardium, Malonate, Myocytes, Cardiac/metabolism, Original Contribution, Heart failure with reduced ejection fraction, Fibrosis, Malonates, Mitochondria, 3. Good health, Mice, Inbred C57BL, Disease Models, Animal, Disease Models, Cardiac/metabolism, Reactive oxygen species

Dateibeschreibung: application/pdf; text/xml

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38864895
https://research.manchester.ac.uk/en/publications/d148d01d-bbfc-44ee-99d9-97a7a64024b4
https://doi.org/10.1007/s00395-024-01063-z
https://www.repository.cam.ac.uk/handle/1810/372727
https://doi.org/10.1007/s00395-024-01063-z
https://www.repository.cam.ac.uk/handle/1810/369563
https://doi.org/10.1007/s00395-024-01063-z

Single and 7-day handgrip and squat exercise prevents endothelial ischemia-reperfusion injury in individuals with cardiovascular disease risk factors

Autoren: Yasina B. Somani Maxime Boidin Mandy A. G. Peggen et al.

Quelle: Somani, Y B, Boidin, M, Peggen, M A G, Wanders, I, Proctor, D N, Low, D A, Jones, H, Lip, G Y H & Thijssen, D H J 2024, 'Single and 7-day handgrip and squat exercise prevents endothelial ischemia-reperfusion injury in individuals with cardiovascular disease risk factors', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 326, no. 1, pp. R79-R87. https://doi.org/10.1152/ajpregu.00168.2023
American Journal of Physiology : Regulatory Integrative and Comparative Physiology, 326, 1, pp. R79-R87

Schlagwörter: Male, Cross-Over Studies, Brachial Artery, Hand Strength, Physiology, ischemia-reperfusion injury, 06 Biological Sciences, Middle Aged, exercise preconditioning, Medical Biosciences - Radboud University Medical Center, cardiovascular disease risk, 3. Good health, Exercise Therapy, Vasodilation, endothelial function, Cardiovascular Diseases, Ischemia, Risk Factors, Reperfusion Injury, Reperfusion Injury/prevention & control, Humans, Female, Endothelium, Vascular, 11 Medical and Health Sciences

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37899755
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/301228
https://doi.org/10.1152/ajpregu.00168.2023
https://vbn.aau.dk/da/publications/49f15cb7-589d-406e-9a26-efecc41876d6
http://www.scopus.com/inward/record.url?scp=85181396275&partnerID=8YFLogxK
https://doi.org/10.1152/ajpregu.00168.2023
https://repository.ubn.ru.nl//bitstream/handle/2066/301228/301228.pdf
https://hdl.handle.net/2066/301228
https://e-space.mmu.ac.uk/633300/

Expanding the horizons of cardioprotection: unveiling a role of nonneuronal cholinergic signaling in hypoxic preconditioning

Autoren: Bøtker, Hans Erik Seefeldt, Jacob Marthinsen

Quelle: Bøtker, H E & Seefeldt, J M 2024, 'Expanding the horizons of cardioprotection : unveiling a role of nonneuronal cholinergic signaling in hypoxic preconditioning', American Journal of Physiology-Heart and Circulatory Physiology, vol. 327, no. 1, pp. H67-H69. https://doi.org/10.1152/ajpheart.00310.2024

Schlagwörter: Myocardium/metabolism, Hypoxia/metabolism, Myocardium, Ischemic Preconditioning, Myocardial, Acetylcholine/metabolism, Myocardial Reperfusion Injury/prevention & control, Animals, Humans, Myocardial Reperfusion Injury, Hypoxia, Acetylcholine, Signal Transduction

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38787387
https://pure.au.dk/portal/en/publications/75f94f90-ad08-445c-a36d-772c8963ac6c
https://doi.org/10.1152/ajpheart.00310.2024
http://www.scopus.com/inward/record.url?scp=85195709580&partnerID=8YFLogxK

Propofol-based versus sevoflurane-based anaesthesia for deceased donor kidney transplantation: the VAPOR-2 study protocol for an international multicentre randomised controlled trial: the VAPOR-2 study protocol for an international multicentre randomised controlled trial

Autoren: Gerrie Joelle Julia Huisman Stefan P Berger Peter S Thyrrestrup et al.

Quelle: BMJ Open. 15:e098965

Schlagwörter: Propofol/administration & dosage, Graft Rejection/prevention & control, Kidney Transplantation/methods, Graft Survival, Sevoflurane/administration & dosage, Tissue Donors, Intravenous/administration & dosage, Inhalation/administration & dosage, Humans, Multicenter Studies as Topic, Reperfusion Injury/prevention & control, Female, Prospective Studies, Delayed Graft Function/prevention & control, Anesthetics, Randomized Controlled Trials as Topic

Zugangs-URL: https://research.rug.nl/en/publications/3c23bef5-6599-47eb-ae49-c045f5624352
https://doi.org/10.1136/bmjopen-2025-098965
https://hdl.handle.net/11370/3c23bef5-6599-47eb-ae49-c045f5624352

Normothermic Machine Perfusion Reconstitutes Porcine Kidney Tissue Metabolism But Induces an Inflammatory Response, Which Is Reduced by Complement C5 Inhibition

Autoren: Eline de Boer Marina Sokolova Neeltina M. Jager et al.

Quelle: Transpl Int
Transplant International, Vol 37 (2024)
Transplant International
de Boer, E, Sokolova, M, Jager, N M, Schjalm, C, Weiss, M G, Liavåg, O M, Maassen, H, van Goor, H, Thorgersen, E B, Pettersen, K, Christiansen, D, Ludviksen, J K, Jespersen, B, Mollnes, T E, Leuvenink, H G D & Pischke, S E 2024, 'Normothermic Machine Perfusion Reconstitutes Porcine Kidney Tissue Metabolism But Induces an Inflammatory Response, Which Is Reduced by Complement C5 Inhibition', Transplant International, vol. 37, 13348. https://doi.org/10.3389/ti.2024.13348

Schlagwörter: 0301 basic medicine, microdialysis, Swine, Microdialysis, ischemia-reperfusion injury, Specialties of internal medicine, Kidney, Health Archive, 03 medical and health sciences, 0302 clinical medicine, Perfusion/methods, Glucose/metabolism, Reperfusion Injury/prevention & control, Animals, Inflammation, Complement C5/antagonists & inhibitors, Microdialysis/methods, renal metabolism, Organ Preservation/methods, Complement C5, Organ Preservation, Kidney Transplantation, Perfusion, Kidney/metabolism, Glucose, RC581-951, inflammation, Reperfusion Injury, normothermic machine perfusion

Dateibeschreibung: application/octet-stream

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39606689
https://doaj.org/article/c476551ac52e4e81b7795f7c667c036c
https://hdl.handle.net/11370/b18887c3-d748-423d-8b98-0c8c16d6269b
https://research.rug.nl/en/publications/b18887c3-d748-423d-8b98-0c8c16d6269b
https://doi.org/10.3389/ti.2024.13348
https://hdl.handle.net/11250/3174682
http://www.scopus.com/inward/record.url?scp=85210491216&partnerID=8YFLogxK
https://pure.au.dk/portal/en/publications/803273bf-5367-465e-b116-5501e99b3b24
https://doi.org/10.3389/ti.2024.13348

Transient heat stress protects from severe endothelial damage and dysfunction during prolonged experimental ex-vivo lung perfusion

Autoren: Roumen Parapanov Anne Debonneville Manon Allouche et al.

Quelle: Front Immunol
Frontiers in Immunology, Vol 15 (2024)
Frontiers in immunology, vol. 15, pp. 1390026

Schlagwörter: Male, 0301 basic medicine, 0303 health sciences, animal model, Immunology, RC581-607, Rats, 3. Good health, Perfusion, Platelet Endothelial Cell Adhesion Molecule-1, 03 medical and health sciences, heat shock response, ex-vivo lung perfusion, pulmonary endothelium, lung ischemia-reperfusion, Reperfusion Injury, lung transplantation, Animals, Lung/pathology, Lung/metabolism, Heat-Shock Response, Perfusion/methods, Reperfusion Injury/metabolism, Reperfusion Injury/prevention & control, Lung Transplantation/adverse effects, Endothelium, Vascular/metabolism, Endothelium, Vascular/pathology, Platelet Endothelial Cell Adhesion Molecule-1/metabolism, heat therapy, Endothelium, Vascular, Immunologic diseases. Allergy, Lung, Lung Transplantation

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38807604
https://doaj.org/article/cf331092e980411e8e7d540934261cfb
https://serval.unil.ch/notice/serval:BIB_3B26095DE465
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_3B26095DE4650
https://serval.unil.ch/resource/serval:BIB_3B26095DE465.P001/REF.pdf

Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury

Autoren: Prag, Hiran A Aksentijevic, Dunja Dannhorn, Andreas et al.

Weitere Verfasser: Prag, Hiran A Aksentijevic, Dunja Dannhorn, Andreas et al.

Quelle: Circ Res
Circulation research, vol. 131, no. 6, pp. 528-541
Prag, H A, Aksentijevic, D, Dannhorn, A, Giles, A V, Mulvey, J F, Sauchanka, O, Du, L, Bates, G, Reinhold, J, Kula-Alwar, D, Xu, Z, Pellerin, L, Goodwin, R J A, Murphy, M P & Krieg, T 2022, 'Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury', Circulation research. https://doi.org/10.1161/CIRCRESAHA.121.320717

Schlagwörter: 0301 basic medicine, Myocardial Reperfusion Injury, ischemia, Mice, 03 medical and health sciences, Ischemia, Tandem Mass Spectrometry, Animals, Humans, Myocytes, Cardiac, Original Research, reactive oxygen species, 0303 health sciences, Chromatography, Liquid, HeLa Cells, Malonates/pharmacology, Malonates/therapeutic use, Mice, Inbred C57BL, Myocardial Reperfusion Injury/drug therapy, Myocardial Reperfusion Injury/prevention & control, mitochondria, myocardial infarction, reperfusion, Malonates, Mitochondria, 3. Good health, Myocardial infarction, Reperfusion, Reactive oxygen species

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/35959683
https://eprints.gla.ac.uk/277333/1/277333.pdf
https://ueaeprints.uea.ac.uk/id/eprint/88804/
https://serval.unil.ch/notice/serval:BIB_1291359D770D
https://serval.unil.ch/resource/serval:BIB_1291359D770D.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1291359D770D5
https://www.repository.cam.ac.uk/handle/1810/340994
https://doi.org/10.1161/circresaha.121.320717
https://doi.org/10.17863/cam.88431
https://www.repository.cam.ac.uk/handle/1810/340850
https://doi.org/10.17863/cam.88285
https://doi.org/10.1161/circresaha.121.320717

Gastric pentadecapeptide BPC 157 in cytoprotection to resolve major vessel occlusion disturbances, ischemia-reperfusion injury following Pringle maneuver, and Budd-Chiari syndrome

Autoren: Sikirić, Predrag Škrtić, Anita Gojković, Slaven et al.

Quelle: World Journal of Gastroenterology. 28:23-46

Schlagwörter: Budd-Chiari syndrome, 0301 basic medicine, 0303 health sciences, Major vessel occlusion disturbances, Therapy, Proteins, Budd-Chiari Syndrome, Anti-Ulcer Agents, Peptide Fragments, Pringle maneuver, 03 medical and health sciences, Reperfusion Injury / drug therapy, Reperfusion Injury / prevention & control, Cytoprotection, Gastric pentadecapeptide BPC 157, Humans

Dateibeschreibung: application/pdf

Exosome-based delivery of super-repressor IκBα ameliorates kidney ischemia-reperfusion injury

Autoren: Myung Yoon Kim Tae Hyun Yoo Dawool Han et al.

Weitere Verfasser: Myung Yoon Kim Tae Hyun Yoo Dawool Han et al.

Quelle: Kidney International. 100:570-584

Schlagwörter: 0301 basic medicine, 0303 health sciences, ischemia-reperfusion injury, NF-ĸB signaling, apoptosis, Acute Kidney Injury, Exosomes, Inbred C57BL, Kidney, 3. Good health, Acute Kidney Injury* / etiology, Mice, Inbred C57BL, Mice, 03 medical and health sciences, acute kidney injury, NF-KappaB Inhibitor alpha, inflammation, Reperfusion Injury, exosome, Animals, Reperfusion Injury* / prevention & control, Acute Kidney Injury* / prevention & control

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/34051264
https://europepmc.org/article/MED/34051264
https://facultyopinions.com/prime/740200041
https://www.ncbi.nlm.nih.gov/pubmed/34051264
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184772
https://pubmed.ncbi.nlm.nih.gov/34051264/
https://www.kidney-international.org/article/S0085-2538(21)00508-1/fulltext

Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial: a randomized trial

Autoren: Rijn, R. van Schurink, I.J. Vries, Y. de et al.

Weitere Verfasser: Rijn, R. van Schurink, I.J. Vries, Y. de et al.

Quelle: New England Journal of Medicine. 384:1391-1401

Schlagwörter: Adult, Male, Constriction, Pathologic, Sciences de la santé humaine, perfusion, 03 medical and health sciences, Medicine, General & Internal, 0302 clinical medicine, General & Internal Medicine, Reperfusion Injury/prevention & control, Humans, Human health sciences, Chirurgie, Biliary Tract, 11 Medical and Health Sciences, Constriction, Pathologic/prevention & control, Science & Technology, 42 Health sciences, liver transplantation, Cold Ischemia, Organ Preservation/methods, 32 Biomedical and clinical sciences, Organ Preservation, Middle Aged, Biliary Tract/pathology, Liver Transplantation, 3. Good health, Cold Temperature, Perfusion, DHOPE-DCD Trial Investigators, Reperfusion Injury, Surgery, Female, Life Sciences & Biomedicine

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/33626248
http://hdl.handle.net/11588/880645
https://research.rug.nl/en/publications/7fa64493-0fc6-4b85-a4c2-d51cb7c4fded
https://hdl.handle.net/11370/7fa64493-0fc6-4b85-a4c2-d51cb7c4fded
https://doi.org/10.1056/NEJMoa2031532
https://research.rug.nl/en/publications/hypothermic-machine-perfusion-in-liver-transplantation-a-randomiz
https://www.nejm.org/doi/full/10.1056/NEJMoa2031532
https://europepmc.org/article/MED/33626248
https://www.nejm.org/doi/suppl/10.1056/NEJMoa2031532/suppl_file/nejmoa2031532_data-sharing.pdf
https://www.ncbi.nlm.nih.gov/pubmed/33626248
https://pubmed.ncbi.nlm.nih.gov/33626248/
https://hdl.handle.net/1887/3270941
https://pure.amsterdamumc.nl/en/publications/86a1d5e6-dd77-4a46-bc39-f908477279a4
https://doi.org/10.1056/NEJMoa2031532
https://hdl.handle.net/2268/311978
https://doi.org/10.1056/NEJMoa2031532
https://biblio.vub.ac.be/vubir/hypothermic-machine-perfusion-in-liver-transplantation--a-randomized-trial(c42ce8b8-9f51-46a7-aa36-cfb5e028afb1).html

Tissue Injury Protection: The Other Face of Anticoagulant Treatments in the Context of Ischemia and Reperfusion Injury with a Focus on Transplantation

Autoren: Carré, Julie Kerforne, Thomas Hauet, Thierry et al.

Weitere Verfasser: Carré, Julie Kerforne, Thomas Hauet, Thierry et al.

Quelle: ISSN: 1661-6596.

Schlagwörter: coagulation, transplantation, thrombo-inflammation, ischemia–reperfusion injury, anticoagulant, MESH: Anticoagulants / therapeutic use, MESH: Humans, MESH: Ischemia, MESH: Organ Transplantation* / adverse effects, MESH: Quality of Life, MESH: Reperfusion Injury* / drug therapy, MESH: Reperfusion Injury* / prevention & control, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

Relation: info:eu-repo/semantics/altIdentifier/pmid/38139319; PUBMED: 38139319

Verfügbarkeit: https://hal.science/hal-04831676
https://hal.science/hal-04831676v1/document
https://hal.science/hal-04831676v1/file/Tissue%20Injury%20Protection_The%20Other%20Face%20of%20Anticoagulant.pdf
https://doi.org/10.3390/ijms242417491

Simplified, controlled limb reperfusion and simultaneous revascularization for acute aortic occlusion

Autoren: Vogt, P. R. von Segesser, L. K. Pagotto, E. et al.

Schlagwörter: Aortic Diseases/complications/*surgery Arterial Occlusive Diseases/complications/*surgery Blood Cardioplegic Solutions/therapeutic use Creatine Kinase/blood Femoral Artery/surgery Humans Ischemia/etiology/*surgery Leg/*blood supply/innervation/surgery Male Middle Aged Muscle, Skeletal/innervation/physiopathology Paralysis/etiology *Reperfusion/methods Reperfusion Injury/prevention & control Sensation Disorders/etiology

Relation: Journal of Vascular Surgery; https://iris.unil.ch/handle/iris/49321; serval:BIB_4C8E0538F612; A1996UJ12600030; 8627914

Verfügbarkeit: https://iris.unil.ch/handle/iris/49321
https://doi.org/10.1016/S0741-5214(96)80058-9

Relation of cardiac troponin I measurements at 24 and 48 hours to magnetic resonance-determined infarct size in patients with ST-elevation myocardial infarction.

Autoren: Hallén, J. Buser, P. Schwitter, J. et al.

Schlagwörter: Aged, Angioplasty, Balloon, Coronary, Austria, Biological Markers/blood, Electrocardiography, Female, Fibrin Fibrinogen Degradation Products/therapeutic use, Heart Conduction System/physiopathology, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Minnesota, Models, Statistical, Myocardial Infarction/blood, Myocardial Infarction/diagnosis, Myocardial Reperfusion Injury/prevention & control, Norway, Peptide Fragments/therapeutic use, Predictive Value of Tests, Prognosis, Randomized Controlled Trials as Topic, Regression Analysis, Research Design, Risk Factors, Sensitivity and Specificity, Switzerland

Relation: American journal of cardiology; https://iris.unil.ch/handle/iris/49105; serval:BIB_3C6C024EE79B; 000272637500003

Verfügbarkeit: https://iris.unil.ch/handle/iris/49105
https://doi.org/10.1016/j.amjcard.2009.07.019

Pilot Trial of Extended Hypothermic Lung Preservation to Analyze Ischemia-reperfusion Injury in Pigs.

Autoren: Ojanguren, A. Santamaría, M. Milla-Collado, L. et al.

Schlagwörter: Animals, Caspase 3, Cytokines, Ischemia/pathology, Lung/pathology, Lung Injury/etiology, Lung Transplantation, Organ Preservation, Pilot Projects, Random Allocation, Reperfusion Injury/prevention & control, Swine, Cold ischemia, Conservación pulmonar, Ischemia-reperfusion injury, Isquemia fría, Lesión de isquemia-reperfusión, Lung preservation, Lung transplant, Modelo porcino, Swine model, Trasplante de pulmón

Relation: Archivos de Bronconeumología; https://iris.unil.ch/handle/iris/225202; serval:BIB_763257483B71; 000674510300009

Verfügbarkeit: https://iris.unil.ch/handle/iris/225202
https://doi.org/10.1016/j.arbr.2021.03.015

Ectopic pacing at physiological rate improves postanoxic recovery of the developing heart.

Autoren: Rosa, A. Maury, J.P. Terrand, J. et al.

Schlagwörter: Animals, Anoxia/physiopathology, Atrioventricular Node/physiology, Cardiac Pacing, Artificial, Chick Embryo, Electrocardiography, Electrophysiology, Glycogen/metabolism, Heart/growth & development, Heart/physiology, Heart Atria, Heart Rate/physiology, Ischemic Preconditioning, Myocardial, Myocardial Contraction/physiology, Myocardial Reperfusion Injury/prevention & control, Myocardium/metabolism, Oxygen Consumption/physiology, Proteins/metabolism, Ventricular Function

Relation: American Journal of Physiology - Heart and Circulatory Physiology; https://iris.unil.ch/handle/iris/221428; serval:BIB_8F9F0B510314; 000182810000062

Verfügbarkeit: https://iris.unil.ch/handle/iris/221428
https://doi.org/10.1152/ajpheart.00758.2002

Impact of an intra-abdominal cooling device during open kidney transplantation in pigs.

Autoren: Longchamp, A. Meier, RPH Colucci, N. et al.

Schlagwörter: Abdominal Cavity, Animals, Body Temperature, Hypothermia, Induced/instrumentation, Kidney/pathology, Kidney Transplantation/methods, Models, Animal, Postoperative Period, Reperfusion Injury/prevention & control, Robotic Surgical Procedures, Swine, Urine, Warm Ischemia

Dateibeschreibung: application/pdf

Relation: Swiss Medical Weekly; https://iris.unil.ch/handle/iris/198036; serval:BIB_CDAD0E3A442A; 000504461600001

Verfügbarkeit: https://iris.unil.ch/handle/iris/198036
https://doi.org/10.4414/smw.2019.20143

1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding.

Autoren: Hannich, J.T. Haribowo, A.G. Gentina, S. et al.

Schlagwörter: Alanine/metabolism, Animals, Genetically Modified, Caenorhabditis elegans, Cell Division, Chaperonins/genetics, Chaperonins/metabolism, Feeding Behavior, Hypoxia/chemically induced, Ion Channels/metabolism, Mice, Inbred C57BL, Mutation, Myocardial Reperfusion Injury/prevention & control, Protein Folding/drug effects, Saccharomyces cerevisiae/metabolism, Serine/metabolism, Sphingosine/analogs & derivatives, Sphingosine/metabolism

Relation: Nature Metabolism; https://iris.unil.ch/handle/iris/186184; serval:BIB_62B2442C63AD; 000500746000011

Verfügbarkeit: https://iris.unil.ch/handle/iris/186184
https://doi.org/10.1038/s42255-019-0123-y

Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.

Autoren: Allam, R. Scherbaum, C.R. Darisipudi, M.N. et al.

Schlagwörter: Acute Kidney Injury/immunology, Acute Kidney Injury/metabolism, Animals, Capillary Permeability, Cytokines/metabolism, Endothelial Cells/physiology, Epithelial Cells/metabolism, Histones/metabolism, Injections, Intra-Arterial, Kidney/pathology, Kidney Tubules/metabolism, Leukocytes/physiology, Lipopolysaccharides, Mice, Inbred C57BL, Myeloid Differentiation Factor 88/metabolism, Necrosis, Renal Artery, Reperfusion Injury/prevention & control, Toll-Like Receptor 2/metabolism, Toll-Like Receptor 4/metabolism

Relation: Journal of the American Society of Nephrology; https://iris.unil.ch/handle/iris/160924; serval:BIB_D1CAA0DE9013; 000309783500015

Verfügbarkeit: https://iris.unil.ch/handle/iris/160924
https://doi.org/10.1681/ASN.2011111077

Poly(ADP-Ribose) polymerase inhibition reduces reperfusion injury after heart transplantation

Autoren: Szabo, G. Bahrle, S. Stumpf, N. et al.

Schlagwörter: Adenosine Diphosphate/metabolism Adenosine Monophosphate/metabolism Adenosine Triphosphate/metabolism Animals Coronary Circulation Enzyme Inhibitors/*pharmacology Heart/drug effects/physiopathology *Heart Transplantation Immunohistochemistry Intercellular Adhesion Molecule-1/analysis Male Myocardial Reperfusion Injury/*prevention & control Myocardium/chemistry/metabolism/pathology P-Selectin/analysis Phenanthrenes/*pharmacology Phosphocreatine/metabolism Poly(ADP-ribose) Polymerases/*antagonists & inhibitors/metabolism Rats Rats, Inbred Lew Time Factors

Relation: Circulation research; https://iris.unil.ch/handle/iris/160458; serval:BIB_B7B9C02D833E; 000173386700019

Verfügbarkeit: https://iris.unil.ch/handle/iris/160458
https://doi.org/10.1161/hh0102.102657

Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion.

Autoren: Seizer, P. Ochmann, C. Schönberger, T. et al.

Schlagwörter: Animals, Antigens, CD147/analysis, CD147/physiology, Cell Adhesion, Cell Movement, Cyclophilin A/analysis, Cyclophilin A/physiology, Humans, Macrophages/physiology, Mice, Inbred C57BL, Myocardial Infarction/metabolism, Myocardial Ischemia/physiopathology, Myocardial Reperfusion Injury/etiology, Myocardial Reperfusion Injury/prevention & control, Neutrophils/physiology, Systole

Dateibeschreibung: application/pdf

Relation: Arteriosclerosis, Thrombosis, and Vascular Biology; https://iris.unil.ch/handle/iris/147870; serval:BIB_B69449C7BC88; 000290719200022

Verfügbarkeit: https://iris.unil.ch/handle/iris/147870
https://doi.org/10.1161/ATVBAHA.111.225771