Suchergebnisse - "Repair"

The histone chaperone CAF-1 prevents homologous recombination-mediated instability of the budding yeast ribosomal DNA during replication-coupled DNA double-strand break repair.

Autoren: Futami H Yamaji T Katayama Y et al.

Quelle: Nucleic acids research [Nucleic Acids Res] 2025 Nov 26; Vol. 53 (22).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

MeSH-Schlagworte: DNA, Ribosomal*/genetics , DNA, Ribosomal*/metabolism , Saccharomyces cerevisiae Proteins*/genetics , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/physiology , DNA Replication* , DNA Breaks, Double-Stranded* , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism , Homologous Recombination* , DNA Repair* , Recombinational DNA Repair* , Histone Chaperones*/genetics , Histone Chaperones*/metabolism, DNA-Binding Proteins/metabolism ; Rad52 DNA Repair and Recombination Protein/metabolism ; Rad52 DNA Repair and Recombination Protein/genetics ; Proliferating Cell Nuclear Antigen/metabolism

Biochemical Effects of Natural and Nanoparticle Fish and Algal Oils in Gilt Pregnancy Diets on Base Excision Repair Enzymes in Newborn Piglets-Socioeconomic Implications for Regional Pig Farming-Preliminary Results.

Autoren: Kowalczyk P Sobol M Makulska J et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 02; Vol. 26 (21). Date of Electronic Publication: 2025 Nov 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Fish Oils*/pharmacology , Fish Oils*/chemistry , Fish Oils*/administration & dosage , Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , DNA Repair*/drug effects , DNA Repair Enzymes*/metabolism , DNA Repair Enzymes*/genetics, Animals ; Female ; Pregnancy ; Swine ; Animals, Newborn ; Fatty Acids, Omega-3/pharmacology ; Dietary Supplements ; Oxidative Stress/drug effects ; Liver/metabolism ; Liver/drug effects ; Diet ; Animal Feed ; DNA Damage ; Excision Repair

Protective role of Cockayne Syndrome B (CSB) protein in maintaining genome integrity in human cells under oxidative stress.

Autoren: Low GKM Ng GY Zeegers D et al.

Quelle: Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2025 Oct; Vol. 907, pp. 503887. Date of Electronic Publication: 2025 Sep 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101632149 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3592 (Electronic) Linking ISSN: 13835718 NLM ISO Abbreviation: Mutat Res Genet Toxicol Environ Mutagen Subsets: MEDLINE

MeSH-Schlagworte: Oxidative Stress*/drug effects , Oxidative Stress*/genetics , DNA Repair Enzymes*/genetics , DNA Repair Enzymes*/metabolism , DNA Repair Enzymes*/physiology , DNA Helicases*/genetics , DNA Helicases*/metabolism , DNA Helicases*/physiology , Genomic Instability* , Genome, Human*, Humans ; Poly-ADP-Ribose Binding Proteins ; Fibroblasts/metabolism ; Fibroblasts/drug effects ; Hydrogen Peroxide/pharmacology ; Hydrogen Peroxide/toxicity ; DNA Damage ; Cellular Senescence/drug effects ; Cellular Senescence/genetics ; DNA Repair ; Cockayne Syndrome/genetics ; Cockayne Syndrome/metabolism ; Telomere/metabolism ; Telomere/genetics ; Cells, Cultured

Proinflammatory macrophage secretome enhances temozolomide sensitivity in glioblastoma via pSTAT3-mediated downregulation of DNA repair enzymes.

Autoren: López-López S Castro-Robles B García-Flores N et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 06; Vol. 15 (1), pp. 38875. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Temozolomide*/pharmacology , Glioblastoma*/drug therapy , Glioblastoma*/metabolism , Glioblastoma*/pathology , Glioblastoma*/genetics , STAT3 Transcription Factor*/metabolism , STAT3 Transcription Factor*/genetics , DNA Repair Enzymes*/metabolism , DNA Repair Enzymes*/genetics , Macrophages*/metabolism , Brain Neoplasms*/drug therapy , Brain Neoplasms*/metabolism , Brain Neoplasms*/pathology, Humans ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; DNA Modification Methylases/metabolism ; DNA Modification Methylases/genetics ; Antineoplastic Agents, Alkylating/pharmacology ; Tumor Suppressor Proteins/metabolism ; Tumor Suppressor Proteins/genetics ; Down-Regulation ; Gene Expression Regulation, Neoplastic/drug effects ; DNA Glycosylases/metabolism ; DNA Glycosylases/genetics ; DNA Repair ; Proteomics ; Tumor Microenvironment ; Phosphorylation

PolySUMOylation of PCNA and Rad52 restricts centromeric recombination in fission yeast.

Autoren: Markowska K Litwin I Misiorna D et al.

Quelle: Nature communications [Nat Commun] 2025 Dec 02; Vol. 16 (1), pp. 10837. Date of Electronic Publication: 2025 Dec 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Schizosaccharomyces*/genetics , Schizosaccharomyces*/metabolism , Schizosaccharomyces pombe Proteins*/metabolism , Schizosaccharomyces pombe Proteins*/genetics , Sumoylation* , Centromere*/metabolism , Centromere*/genetics , Rad52 DNA Repair and Recombination Protein*/metabolism , Rad52 DNA Repair and Recombination Protein*/genetics , Proliferating Cell Nuclear Antigen*/metabolism , Proliferating Cell Nuclear Antigen*/genetics , Recombination, Genetic*, DNA Replication ; DNA Repair ; DNA Damage ; Ubiquitination ; DNA-Binding Proteins

Exploring the interaction between nucleotide excision repair pathways and Huntington disease: Implications for neurodegeneration and phenotypic overlap.

Autoren: Natalia GR Emiliano CM Melisa E et al.

Quelle: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2025 Dec; Vol. 141, pp. 108091. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5126 (Electronic) Linking ISSN: 13538020 NLM ISO Abbreviation: Parkinsonism Relat Disord Subsets: MEDLINE

MeSH-Schlagworte: DNA Repair*/physiology , Huntington Disease*/genetics , Huntington Disease*/metabolism , Neurodegenerative Diseases*/genetics, Humans ; Phenotype ; Animals ; Cockayne Syndrome/genetics ; Xeroderma Pigmentosum/genetics ; DNA Damage ; Excision Repair

Emerging insights into alternative end‑joining: Mechanisms, genome instability and therapeutic opportunities in cancer (Review).

Autoren: Azam N Liu X Li X et al.

Quelle: International journal of oncology [Int J Oncol] 2025 Dec; Vol. 67 (6). Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9306042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-2423 (Electronic) Linking ISSN: 10196439 NLM ISO Abbreviation: Int J Oncol Subsets: MEDLINE

MeSH-Schlagworte: Neoplasms*/genetics , Neoplasms*/therapy , Neoplasms*/pathology , Neoplasms*/drug therapy , Genomic Instability* , DNA End-Joining Repair*/genetics, Humans ; DNA Breaks, Double-Stranded/drug effects ; Animals ; DNA Repair

Base excision repair in chromatin: A tug-of-war for DNA damage.

Autoren: Vito AF Boesch DJ Hammons AM et al.

Quelle: DNA repair [DNA Repair (Amst)] 2025 Nov; Vol. 155, pp. 103908. Date of Electronic Publication: 2025 Oct 23.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139138 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-7856 (Electronic) Linking ISSN: 15687856 NLM ISO Abbreviation: DNA Repair (Amst) Subsets: MEDLINE

MeSH-Schlagworte: DNA Repair* , DNA Damage* , Chromatin*/metabolism , Chromatin*/genetics , DNA*/metabolism , DNA*/chemistry, Nucleosomes/metabolism ; Nucleosomes/genetics ; Humans ; Chromatin Assembly and Disassembly ; Animals ; Histones/metabolism ; Excision Repair

Break-induced replication is activated to repair R-loop-associated double-strand breaks in SETX-deficient cells.

Autoren: Wu T Li Y Zhao Y et al.

Quelle: Cell reports [Cell Rep] 2025 Oct 28; Vol. 44 (10), pp. 116386. Date of Electronic Publication: 2025 Oct 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: DNA Breaks, Double-Stranded* , DNA Replication* , R-Loop Structures* , DNA Repair* , DNA Helicases*/metabolism , DNA Helicases*/deficiency , DNA Helicases*/genetics , RNA Helicases*/metabolism , RNA Helicases*/deficiency , RNA Helicases*/genetics, Humans ; Rad52 DNA Repair and Recombination Protein/metabolism ; Rad52 DNA Repair and Recombination Protein/genetics ; Multifunctional Enzymes/deficiency ; Proliferating Cell Nuclear Antigen/metabolism ; Ubiquitination ; DNA-Binding Proteins/metabolism ; DNA, Single-Stranded/metabolism

Population frequency of Predicted pathogenic MisMatch Repair (MMR) gene variants in Lynch syndrome from bioinformatic analyses of the general population.

Autoren: Guan Y Huang M Macrae F et al.

Quelle: Scientific reports [Sci Rep] 2025 Oct 03; Vol. 15 (1), pp. 34545. Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics , Colorectal Neoplasms, Hereditary Nonpolyposis*/epidemiology , DNA Mismatch Repair*/genetics , Computational Biology*/methods, Humans ; Genetic Predisposition to Disease ; DNA-Binding Proteins/genetics ; Germ-Line Mutation ; Gene Frequency ; Mismatch Repair Endonuclease PMS2/genetics ; MutL Protein Homolog 1/genetics

RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA.

Autoren: An H Xia A Liu S et al.

Quelle: Cell proliferation [Cell Prolif] 2025 Oct; Vol. 58 (10), pp. e70059. Date of Electronic Publication: 2025 May 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9105195 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2184 (Electronic) Linking ISSN: 09607722 NLM ISO Abbreviation: Cell Prolif Subsets: MEDLINE

MeSH-Schlagworte: DNA Glycosylases*/genetics , DNA Glycosylases*/metabolism , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Carcinoma, Hepatocellular*/genetics , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Liver Neoplasms*/genetics , Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , DNA Repair*/genetics, Humans ; Animals ; Cell Proliferation/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Mice ; Oxidative Stress ; Cell Line, Tumor ; Cell Movement/genetics ; Mice, Nude ; Gene Expression Regulation, Neoplastic ; Disease Progression ; Mice, Inbred BALB C ; Apoptosis/genetics ; RNA Stability ; Excision Repair

Transcription-coupled repair: tangled up in convoluted repair.

Autoren: Llerena Schiffmacher DA Pai YJ Pines A et al.

Quelle: The FEBS journal [FEBS J] 2025 Oct; Vol. 292 (20), pp. 5288-5323. Date of Electronic Publication: 2025 Apr 24.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

MeSH-Schlagworte: DNA Repair*/genetics , Transcription, Genetic* , Cockayne Syndrome*/genetics , Cockayne Syndrome*/pathology , Cockayne Syndrome*/metabolism, Humans ; RNA Polymerase II/genetics ; RNA Polymerase II/metabolism ; Cryoelectron Microscopy ; DNA Damage/genetics ; Animals ; Protein Processing, Post-Translational/genetics ; Chromatin/genetics ; Chromatin/ultrastructure ; Chromatin/metabolism ; Excision Repair

Inhibition of nucleotide excision repair proteins associated with cancer chemotherapy.

Autoren: Gentile F Cros-Perrial E Jordheim LP

Quelle: Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2025 Oct; Vol. 1880 (5), pp. 189408. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9806362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2561 (Electronic) Linking ISSN: 0304419X NLM ISO Abbreviation: Biochim Biophys Acta Rev Cancer Subsets: MEDLINE

MeSH-Schlagworte: DNA Repair*/drug effects , Neoplasms*/drug therapy , Neoplasms*/genetics , Neoplasms*/metabolism , DNA-Binding Proteins*/antagonists & inhibitors , DNA-Binding Proteins*/metabolism , Endonucleases*/antagonists & inhibitors , Endonucleases*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use, Humans ; Animals ; Excision Repair

Dysfunctional mismatch repair in patients with early triple-negative breast cancer.

Autoren: Muñiz-Castrillo M Blaya Boluda N García-Torralba E et al.

Quelle: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2025 Oct; Vol. 27 (10), pp. 3924-3937. Date of Electronic Publication: 2025 May 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Italia Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE

MeSH-Schlagworte: Triple Negative Breast Neoplasms*/genetics , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/mortality , DNA Mismatch Repair*/genetics, Humans ; Female ; Middle Aged ; Microsatellite Instability ; Mismatch Repair Endonuclease PMS2/genetics ; Adult ; Aged ; Prognosis ; Germ-Line Mutation

WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair.

Autoren: Lu YF Tang H Di L et al.

Quelle: Cell reports [Cell Rep] 2025 Nov 25; Vol. 44 (11), pp. 116520. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: Recombinational DNA Repair* , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/genetics, Humans ; MRE11 Homologue Protein/metabolism ; MRE11 Homologue Protein/genetics ; DNA Breaks, Double-Stranded ; Cell Cycle Proteins/metabolism ; Cell Cycle Proteins/genetics ; Phosphorylation ; Nuclear Proteins/metabolism ; DNA Repair Enzymes/metabolism ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Acid Anhydride Hydrolases ; Animals ; Checkpoint Kinase 2/metabolism ; HEK293 Cells ; Homologous Recombination ; Mice ; Multiprotein Complexes/metabolism

53BP1-RIF1 and DNA-PKcs show distinct genetic interactions with diverse chromosomal break repair outcomes.

Autoren: Makins K Cisneros-Aguirre M Lopezcolorado FW et al.

Quelle: Nature communications [Nat Commun] 2025 Nov 24; Vol. 16 (1), pp. 10361. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Tumor Suppressor p53-Binding Protein 1*/genetics , Tumor Suppressor p53-Binding Protein 1*/metabolism , DNA-Activated Protein Kinase*/metabolism , DNA-Activated Protein Kinase*/genetics , DNA End-Joining Repair*/genetics , Telomere-Binding Proteins*/metabolism , Telomere-Binding Proteins*/genetics, DNA Breaks, Double-Stranded ; Animals ; Humans ; Mice ; Radiation Tolerance/genetics ; DNA Repair

HAT1 functions as a lactyltransferase and mediates RPA1 lactylation to promote DNA repair and radioresistance in lung adenocarcinoma.

Autoren: He J Lai T Zhao Y et al.

Quelle: Cell death & disease [Cell Death Dis] 2025 Nov 21; Vol. 16 (1), pp. 851. Date of Electronic Publication: 2025 Nov 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

MeSH-Schlagworte: Adenocarcinoma of Lung*/genetics , Adenocarcinoma of Lung*/radiotherapy , Adenocarcinoma of Lung*/pathology , Adenocarcinoma of Lung*/metabolism , Replication Protein A*/metabolism , Replication Protein A*/genetics , DNA Repair*/genetics , Radiation Tolerance*/genetics , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/radiotherapy , Lung Neoplasms*/metabolism, Humans ; Cell Line, Tumor ; Homologous Recombination ; DNA-Binding Proteins/metabolism ; MRE11 Homologue Protein/metabolism ; DNA Repair Enzymes/metabolism ; Acid Anhydride Hydrolases

Investigating somatic variants and pathways in mismatch repair-deficient (dMMR) colorectal carcinoma in South Africa.

Autoren: Aldera AP van der Westhuizen J Tsai WJ et al.

Quelle: Journal of clinical pathology [J Clin Pathol] 2025 Nov 19; Vol. 78 (12), pp. 848-854. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 0376601 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-4146 (Electronic) Linking ISSN: 00219746 NLM ISO Abbreviation: J Clin Pathol Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , DNA Mismatch Repair*/genetics , Biomarkers, Tumor*/genetics, Humans ; Female ; South Africa ; Male ; Middle Aged ; Adult ; MutL Protein Homolog 1/genetics ; Mismatch Repair Endonuclease PMS2/genetics ; High-Throughput Nucleotide Sequencing ; Mutation ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; DNA-Binding Proteins/genetics ; Genetic Predisposition to Disease ; MutS Homolog 2 Protein/genetics ; DNA Polymerase III/genetics ; Young Adult

Expanding the landscape of nucleotide excision repair disorders: from discovery to therapy.

Autoren: Theil AF Hoeijmakers JH

Quelle: The Journal of clinical investigation [J Clin Invest] 2025 Nov 17; Vol. 135 (22). Date of Electronic Publication: 2025 Nov 17 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

MeSH-Schlagworte: DNA Repair* , Xeroderma Pigmentosum*/genetics , Xeroderma Pigmentosum*/therapy , Xeroderma Pigmentosum*/metabolism , Xeroderma Pigmentosum*/pathology , Transcription Factor TFIIH*/genetics , Transcription Factor TFIIH*/metabolism , Cockayne Syndrome*/genetics , Cockayne Syndrome*/therapy , Cockayne Syndrome*/metabolism , Cockayne Syndrome*/pathology , Trichothiodystrophy Syndromes*/genetics , Trichothiodystrophy Syndromes*/therapy , Trichothiodystrophy Syndromes*/metabolism , Trichothiodystrophy Syndromes*/pathology, Humans ; DNA Damage ; Excision Repair

Chromatin context shapes DNA damage formation and nucleotide excision repair dynamics in Caenorhabditis elegans.

Autoren: Kose C Azgari C Lindsey-Boltz LA et al.

Quelle: Nucleic acids research [Nucleic Acids Res] 2025 Oct 28; Vol. 53 (20).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

MeSH-Schlagworte: Caenorhabditis elegans*/genetics , Caenorhabditis elegans*/radiation effects , Caenorhabditis elegans*/metabolism , DNA Repair* , DNA Damage* , Chromatin*/metabolism , Chromatin*/genetics, Animals ; Ultraviolet Rays ; Nucleosomes/metabolism ; Transcription, Genetic ; Pyrimidine Dimers/metabolism ; Excision Repair