Suchergebnisse - "Regulatory Factor X Transcription Factors"

Structural basis of nucleosome binding and destabilization by the extended DNA binding domain of RFX5.

Autoren: Xue W Han Y Tian Y et al.

Quelle: Nucleic acids research [Nucleic Acids Res] 2025 Jul 19; Vol. 53 (14).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

MeSH-Schlagworte: Nucleosomes*/metabolism , Nucleosomes*/chemistry , Nucleosomes*/ultrastructure , Nucleosomes*/genetics , DNA*/metabolism , DNA*/chemistry , Regulatory Factor X Transcription Factors*/chemistry , Regulatory Factor X Transcription Factors*/metabolism , Regulatory Factor X Transcription Factors*/genetics , Regulatory Factor X Transcription Factors*/ultrastructure , DNA-Binding Proteins*/chemistry , DNA-Binding Proteins*/metabolism, Protein Binding ; Humans ; Protein Domains ; Histones/metabolism ; Histones/chemistry ; Cryoelectron Microscopy ; Models, Molecular ; Binding Sites

RFX3 is essential for the generation of functional human pancreatic islets from stem cells.

Autoren: Memon B Aldous N Elsayed AK et al.

Quelle: Diabetologia [Diabetologia] 2025 Jul; Vol. 68 (7), pp. 1476-1491. Date of Electronic Publication: 2025 Apr 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

MeSH-Schlagworte: Islets of Langerhans*/metabolism , Islets of Langerhans*/cytology , Regulatory Factor X Transcription Factors*/metabolism , Regulatory Factor X Transcription Factors*/genetics , Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/cytology, Humans ; Cell Differentiation/physiology ; Cell Differentiation/genetics

RFX5 promotes the progression of triple-negative breast cancer through transcriptional activation of JAG1.

Autoren: Li C Wang X Shi D et al.

Quelle: Human cell [Hum Cell] 2025 Apr 12; Vol. 38 (3), pp. 86. Date of Electronic Publication: 2025 Apr 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Japan NLM ID: 8912329 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-0774 (Electronic) Linking ISSN: 09147470 NLM ISO Abbreviation: Hum Cell Subsets: MEDLINE

MeSH-Schlagworte: Triple Negative Breast Neoplasms*/genetics , Triple Negative Breast Neoplasms*/pathology , Disease Progression* , Jagged-1 Protein*/genetics , Jagged-1 Protein*/metabolism , Transcriptional Activation*/genetics , Regulatory Factor X Transcription Factors*/genetics , Regulatory Factor X Transcription Factors*/physiology, Humans ; Female ; Cell Proliferation/genetics ; Cell Movement/genetics ; Signal Transduction/genetics ; Apoptosis/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Neoplasm Invasiveness/genetics ; Cell Line, Tumor ; Up-Regulation/genetics ; Receptors, Notch/metabolism ; Gene Knockdown Techniques

A patient with RFX5 variant causing an expression defect in both HLA ABC and HLA DR.

Autoren: Goktas S Sonmez G Şahin A et al.

Quelle: Immunologic research [Immunol Res] 2025 Apr 16; Vol. 73 (1), pp. 72. Date of Electronic Publication: 2025 Apr 16.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 8611087 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-0755 (Electronic) Linking ISSN: 0257277X NLM ISO Abbreviation: Immunol Res Subsets: MEDLINE

MeSH-Schlagworte: Regulatory Factor X Transcription Factors*/genetics , HLA-DR Antigens*/genetics , HLA-DR Antigens*/metabolism , DNA-Binding Proteins*/genetics , Transcription Factors*/genetics , Severe Combined Immunodeficiency*/genetics , Severe Combined Immunodeficiency*/diagnosis, Humans ; Male ; Mutation ; Hematopoietic Stem Cell Transplantation

CKAP2L Plays a Pivotal Role in Colorectal Cancer Progression via the Dual Regulation of Cell Cycle and Epithelial-Mesenchymal Transition.

Autoren: Luo Q Zhu B Wang C et al.

Quelle: Discovery medicine [Discov Med] 2025 Jan; Vol. 37 (192), pp. 182-192.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Discovery medicine Country of Publication: United States NLM ID: 101250006 Publication Model: Print Cited Medium: Internet ISSN: 1944-7930 (Electronic) Linking ISSN: 15396509 NLM ISO Abbreviation: Discov Med Subsets: MEDLINE

MeSH-Schlagworte: Cytoskeletal Proteins*/analysis , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/metabolism , Regulatory Factor X Transcription Factors*/analysis , Regulatory Factor X Transcription Factors*/genetics , Regulatory Factor X Transcription Factors*/metabolism , Colonic Neoplasms*/diagnosis , Colonic Neoplasms*/genetics , Colonic Neoplasms*/pathology , Rectal Neoplasms*/diagnosis , Rectal Neoplasms*/genetics , Rectal Neoplasms*/pathology , Adenocarcinoma*/diagnosis , Adenocarcinoma*/genetics , Adenocarcinoma*/pathology, Disease Progression ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Humans ; Epithelial-Mesenchymal Transition/genetics ; Cell Proliferation/genetics ; Cell Movement/genetics ; Neoplasm Invasiveness/genetics ; G1 Phase Cell Cycle Checkpoints/genetics ; TOR Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/genetics ; Gene Expression Profiling

Rare forms of monogenic diabetes in non-European individuals. First reports of CEL and RFX6 mutations from the Indian subcontinent.

Autoren: Marucci A Menzaghi C Dodesini AR et al.

Quelle: Acta diabetologica [Acta Diabetol] 2025 Mar; Vol. 62 (3), pp. 323-328. Date of Electronic Publication: 2024 Aug 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9200299 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-5233 (Electronic) Linking ISSN: 09405429 NLM ISO Abbreviation: Acta Diabetol Subsets: MEDLINE

MeSH-Schlagworte: Diabetes Mellitus*/genetics , Mutation* , Regulatory Factor X Transcription Factors*/genetics, Humans ; India ; Pedigree

Deletion of RFX6 impairs iPSC-derived islet organoid development and survival, with no impact on PDX1 ⁺ /NKX6.1 ⁺ progenitors.

Autoren: Aldous N Elsayed AK Memon B et al.

Quelle: Diabetologia [Diabetologia] 2024 Dec; Vol. 67 (12), pp. 2786-2803. Date of Electronic Publication: 2024 Jul 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

MeSH-Schlagworte: Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/cytology , Regulatory Factor X Transcription Factors*/genetics , Regulatory Factor X Transcription Factors*/metabolism , Homeodomain Proteins*/metabolism , Homeodomain Proteins*/genetics , Cell Differentiation*/genetics , Cell Differentiation*/physiology , Organoids*/metabolism , Islets of Langerhans*/metabolism , Islets of Langerhans*/cytology , Trans-Activators*/genetics , Trans-Activators*/metabolism, Humans ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics

2-Chloroethanol induces hepatic toxicity by disrupting endoplasmic reticulum homeostasis ameliorated by dimethyl sulfoxide.

Autoren: Chou TH Hu MH Hua KT et al.

Quelle: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Nov; Vol. 1871 (8), pp. 168017. Date of Electronic Publication: 2025 Aug 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE

MeSH-Schlagworte: Dimethyl Sulfoxide*/pharmacology , Endoplasmic Reticulum*/metabolism , Endoplasmic Reticulum*/drug effects , Endoplasmic Reticulum*/pathology , Homeostasis*/drug effects , Liver*/metabolism , Liver*/drug effects , Liver*/pathology , Chemical and Drug Induced Liver Injury*/metabolism , Chemical and Drug Induced Liver Injury*/pathology , Chemical and Drug Induced Liver Injury*/drug therapy, Animals ; Mice ; Unfolded Protein Response/drug effects ; Endoplasmic Reticulum Stress/drug effects ; X-Box Binding Protein 1 ; Signal Transduction/drug effects ; Transcription Factor CHOP/metabolism ; Transcription Factor CHOP/genetics ; Humans ; Protein Serine-Threonine Kinases/metabolism ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Protein Serine-Threonine Kinases/genetics ; Male ; Endoribonucleases/metabolism ; Endoribonucleases/antagonists & inhibitors ; Endoribonucleases/genetics ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; Cell Line, Tumor ; Eukaryotic Initiation Factor-2/metabolism ; Mice, Inbred C57BL ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Regulatory Factor X Transcription Factors ; Apoptosis/drug effects ; Activating Transcription Factor 6/metabolism

An Inherited Allele Confers Prostate Cancer Progression and Drug Resistance via RFX6/HOXA10-Orchestrated TGFβ Signaling.

Autoren: Zhong M Xu W Tian P et al.

Quelle: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Aug; Vol. 11 (32), pp. e2401492. Date of Electronic Publication: 2024 Jun 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

MeSH-Schlagworte: Alleles* , Disease Progression* , Drug Resistance, Neoplasm*/genetics , Homeodomain Proteins*/genetics , Homeodomain Proteins*/metabolism , Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/metabolism , Prostatic Neoplasms*/pathology , Regulatory Factor X Transcription Factors*/genetics , Regulatory Factor X Transcription Factors*/metabolism , Signal Transduction*/genetics , Transforming Growth Factor beta*/metabolism , Transforming Growth Factor beta*/genetics, Animals ; Humans ; Male ; Mice ; Cell Line, Tumor ; Disease Models, Animal ; Genome-Wide Association Study/methods

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function.

Autoren: Ibrahim H Balboa D Saarimäki-Vire J et al.

Quelle: Diabetologia [Diabetologia] 2024 Aug; Vol. 67 (8), pp. 1642-1662. Date of Electronic Publication: 2024 May 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

MeSH-Schlagworte: Insulin-Secreting Cells*/metabolism , Haploinsufficiency* , Regulatory Factor X Transcription Factors*/genetics , Regulatory Factor X Transcription Factors*/metabolism, Animals ; Humans ; Mice ; Cell Differentiation/genetics ; Mice, Inbred NOD ; Mice, SCID ; Genetic Predisposition to Disease ; Female ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Nerve Tissue Proteins

MHC Class II Deficiency: Clinical, Immunological, and Genetic Insights in a Large Multicenter Cohort.

Autoren: Gulec Koksal Z Bilgic Eltan S Topyildiz E et al.

Quelle: The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2024 Sep; Vol. 12 (9), pp. 2490-2502.e6. Date of Electronic Publication: 2024 Jul 10.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101597220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2201 (Electronic) NLM ISO Abbreviation: J Allergy Clin Immunol Pract Subsets: MEDLINE

MeSH-Schlagworte: Mutation* , DNA-Binding Proteins*/genetics , Regulatory Factor X Transcription Factors*/genetics, Humans ; Male ; Female ; Child, Preschool ; Infant ; Retrospective Studies ; Child ; Transcription Factors/genetics ; Turkey/epidemiology ; Nuclear Proteins/genetics ; Trans-Activators/genetics ; Hematopoietic Stem Cell Transplantation ; Histocompatibility Antigens Class II/genetics ; Pneumonia/genetics ; Adolescent ; Cohort Studies ; Diarrhea/genetics ; Severe Combined Immunodeficiency/genetics ; Severe Combined Immunodeficiency/therapy ; Prognosis

RFX6 regulates human intestinal patterning and function upstream of PDX1.

Autoren: Sanchez JG Rankin S Paul E et al.

Quelle: Development (Cambridge, England) [Development] 2024 May 01; Vol. 151 (9). Date of Electronic Publication: 2024 May 09.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Info zur Zeitschrift: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

MeSH-Schlagworte: Regulatory Factor X Transcription Factors*/genetics , Regulatory Factor X Transcription Factors*/metabolism , Homeodomain Proteins*/metabolism , Homeodomain Proteins*/genetics , Trans-Activators*/metabolism , Trans-Activators*/genetics , Organoids*/metabolism , Organoids*/embryology , Gene Expression Regulation, Developmental*, Humans ; Animals ; Duodenum/metabolism ; Duodenum/embryology ; Intestines/embryology ; Intestinal Atresia/genetics ; Induced Pluripotent Stem Cells/metabolism ; Body Patterning/genetics ; Signal Transduction/genetics ; Mutation/genetics

Precise progerin targeting using RfxCas13d: A therapeutic avenue for Hutchinson-Gilford progeria syndrome.

Autoren: Chae U Yang HJ Kim H et al.

Quelle: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2025 Sep 03; Vol. 33 (9), pp. 4394-4413. Date of Electronic Publication: 2025 Jun 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

MeSH-Schlagworte: Progeria*/genetics , Progeria*/therapy , Progeria*/metabolism , Lamin Type A*/genetics , Lamin Type A*/metabolism, Animals ; Mice ; Humans ; Disease Models, Animal ; RNA, Messenger/genetics ; Regulatory Factor X Transcription Factors/genetics ; Phenotype ; RNA Splicing ; DNA Damage

Novel Sarcoidosis Epitope Augments MHCII, CD80, and CD86 Expression and Promotes B-Cell Differentiation and IgG Production.

Autoren: Talreja J Peng C Zhang K et al.

Quelle: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2025 Jul; Vol. 73 (1), pp. 135-146.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: Immunoglobulin G*/immunology , Immunoglobulin G*/biosynthesis , Cell Differentiation*/immunology , B-Lymphocytes*/immunology , B-Lymphocytes*/metabolism , Sarcoidosis*/immunology , Histocompatibility Antigens Class II*/immunology , Histocompatibility Antigens Class II*/metabolism , B7-2 Antigen*/immunology , B7-2 Antigen*/metabolism , Epitopes*/immunology , B7-1 Antigen*/immunology , B7-1 Antigen*/metabolism, Humans ; Animals ; X-Box Binding Protein 1 ; Positive Regulatory Domain I-Binding Factor 1 ; Lymphocyte Activation/immunology ; Plasma Cells/immunology ; Male ; Female ; Unfolded Protein Response ; Mice ; Adult ; Middle Aged ; Leukocytes, Mononuclear/immunology ; Regulatory Factor X Transcription Factors ; Transcription Factors/metabolism

Screening of Mutations in Maturity-onset Diabetes of the Young-related Genes and RFX6 in Children with Autoantibody-negative Type 1 Diabetes Mellitus

Autoren: Şimşek E Çilingir O Şimşek T et al.

Quelle: Journal of clinical research in pediatric endocrinology [J Clin Res Pediatr Endocrinol] 2024 May 31; Vol. 16 (2), pp. 137-145. Date of Electronic Publication: 2023 Dec 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Galenos Yayınevi Country of Publication: Turkey NLM ID: 101519456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1308-5735 (Electronic) NLM ISO Abbreviation: J Clin Res Pediatr Endocrinol Subsets: MEDLINE

MeSH-Schlagworte: Mutation* , Diabetes Mellitus, Type 1*/genetics , Diabetes Mellitus, Type 1*/diagnosis , Diabetes Mellitus, Type 1*/immunology , Regulatory Factor X Transcription Factors*/genetics , Autoantibodies*/blood , Genetic Testing*, Humans ; Child ; Male ; Female ; Adolescent ; Child, Preschool ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/diagnosis

SCR Disease Name: Mason-Type Diabetes

RFX4 is an intrinsic factor for neuronal differentiation through induction of proneural genes POU3F2 and NEUROD1.

Autoren: Choi W Choe MS Kim SM et al.

Quelle: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Feb 22; Vol. 81 (1), pp. 99. Date of Electronic Publication: 2024 Feb 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

MeSH-Schlagworte: Basic Helix-Loop-Helix Transcription Factors*/genetics , Neurons* , Homeodomain Proteins*/genetics , POU Domain Factors*/genetics , Regulatory Factor X Transcription Factors*/genetics, Humans ; Gene Expression Profiling ; Promoter Regions, Genetic ; RNA-Seq ; Cell Differentiation

Prognostic implications of MUC1 and XBP1 concordant expression in multiple myeloma: A retrospective study.

Autoren: Rajput SK Minhas K Azam I et al.

Quelle: PloS one [PLoS One] 2025 Apr 03; Vol. 20 (4), pp. e0320934. Date of Electronic Publication: 2025 Apr 03 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Mucin-1*/metabolism , Mucin-1*/genetics , X-Box Binding Protein 1*/metabolism , Multiple Myeloma*/metabolism , Multiple Myeloma*/pathology , Multiple Myeloma*/mortality , Multiple Myeloma*/diagnosis , Multiple Myeloma*/genetics , DNA-Binding Proteins*/metabolism , Transcription Factors*/metabolism, Humans ; Female ; Male ; Prognosis ; Middle Aged ; Aged ; Retrospective Studies ; Biomarkers, Tumor/metabolism ; Adult ; Aged, 80 and over ; Regulatory Factor X Transcription Factors ; Gene Expression Regulation, Neoplastic ; Kaplan-Meier Estimate ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology

Diff erent expression of genes involved in unfolded protein response in multiple myeloma and extramedullary dis ease patients.

Transliterierter Titel: Odlišná exprese genů spojených se signální drahou UPR u pacientů s mnohočetným myelomem a extramedulárním onemocněním.

Autoren: Dostálová A Vlachová M Růžičková T et al.

Quelle: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti [Klin Onkol] 2025; Vol. 38 (1), pp. 45-51.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Ceská lékarská spolecnost Country of Publication: Czech Republic NLM ID: 9425213 Publication Model: Print Cited Medium: Internet ISSN: 1802-5307 (Electronic) Linking ISSN: 0862495X NLM ISO Abbreviation: Klin Onkol Subsets: MEDLINE

MeSH-Schlagworte: Multiple Myeloma*/genetics , Multiple Myeloma*/metabolism , Multiple Myeloma*/pathology , Unfolded Protein Response*/genetics, Humans ; Endoplasmic Reticulum Chaperone BiP ; X-Box Binding Protein 1/genetics ; Endoribonucleases/genetics ; Heat-Shock Proteins/genetics ; Transcription Factor CHOP/genetics ; Protein Serine-Threonine Kinases/genetics ; Aged ; Middle Aged ; Male ; Regulatory Factor X Transcription Factors ; Female ; Plasma Cells/metabolism ; eIF-2 Kinase

Suppression of NF-κB and downstream XBP1 by DcR3 contributes to a decrease in antibody secretion.

Autoren: Liu PC Huang SY Lin KI et al.

Quelle: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2025 Jan 01; Vol. 214 (1), pp. 72-84.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Tumor Necrosis Factor, Member 6b*/genetics , Receptors, Tumor Necrosis Factor, Member 6b*/immunology , Receptors, Tumor Necrosis Factor, Member 6b*/metabolism , NF-kappa B*/metabolism , NF-kappa B*/immunology , NF-kappa B*/antagonists & inhibitors , NF-kappa B*/genetics , DNA-Binding Proteins*/genetics , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/immunology , B-Lymphocytes*/immunology , Antibody Formation*/immunology , Transcription Factors*/genetics , Transcription Factors*/metabolism , Transcription Factors*/immunology, Animals ; X-Box Binding Protein 1 ; Mice ; Mice, Transgenic ; Regulatory Factor X Transcription Factors ; Mice, Inbred C57BL ; Lymphocyte Activation/immunology ; Humans

Phenotype expansion and neurological manifestations of neurobehavioural disease caused by a variant in RFX7.

Autoren: Ledger ML Kaare M Mailo JA et al.

Quelle: European journal of medical genetics [Eur J Med Genet] 2023 Jan; Vol. 66 (1), pp. 104657. Date of Electronic Publication: 2022 Nov 09.

Publikationsart: Case Reports; Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101247089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0849 (Electronic) Linking ISSN: 17697212 NLM ISO Abbreviation: Eur J Med Genet Subsets: MEDLINE

MeSH-Schlagworte: Intellectual Disability*/genetics , Language Development Disorders*/genetics , Regulatory Factor X Transcription Factors*/genetics, Child ; Humans ; Infant ; Autism Spectrum Disorder/genetics ; Failure to Thrive ; Phenotype